Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YHR016C
Length:
468
Number of sequences:
5887
Description:
YHR016C YSC84 SGDID:S000001058, Chr VIII from 138240-136881,138455-138409, Genome Release 64-1-1, reverse complement, Verified ORF, "Actin-binding protein involved in bundling of actin filaments and endocytosis of actin cortical patches; activity stimulated by Las17p; contains SH3 domain similar to Rvs167p"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
511Q08881    620   ITK_HUMAN Tyrosine-protein kinase ITK/TSK OS=...541.5     35     30     54GO:0005829; C:cytosol; TAS:Reactome.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IDA:UniProtKB.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0007202; P:activation of phospholipase C activity; ISS:UniProtKB.::GO:0002250; P:adaptive immune response; ISS:UniProtKB.::GO:0006968; P:cellular defense response; TAS:ProtInc.::GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0050852; P:T cell receptor signaling pathway; ISS:UniProtKB.
512P40996    536   SCD2_SCHPO Protein scd2/ral3 OS=Schizosacchar...561.6     35     25     59GO:0071521; C:Cdc42 GTPase complex; TAS:PomBase.::GO:0032153; C:cell division site; IDA:PomBase.::GO:0051286; C:cell tip; IDA:PomBase.::GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.
GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0032488; P:Cdc42 protein signal transduction; TAS:PomBase.::GO:0031137; P:regulation of conjugation with cellular fusion; IMP:PomBase.::GO:0032878; P:regulation of establishment or maintenance of cell polarity; IMP:PomBase.
513Q9UJU6    430   DBNL_HUMAN Drebrin-like protein OS=Homo sapie...801.6     34.7     28     48GO:0005938; C:cell cortex; ISS:UniProtKB.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0030027; C:lamellipodium; ISS:UniProtKB.
GO:0003779; F:actin binding; ISS:UniProtKB.::GO:0008047; F:enzyme activator activity; TAS:ProtInc.
GO:0007257; P:activation of JUN kinase activity; TAS:ProtInc.::GO:0006921; P:cellular component disassembly involved in apoptotic process; TAS:Reactome.::GO:0006897; P:endocytosis; IEA:UniProtKB-KW.::GO:0016601; P:Rac protein signal transduction; ISS:UniProtKB.
514Q6GNV5    610   FNBP1_XENLA Formin-binding protein 1 homolog ...571.6     35     30     56GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell.::GO:0016023; C:cytoplasmic membrane-bounded vesicle; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005764; C:lysosome; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0008289; F:lipid binding; IEA:UniProtKB-KW.
GO:0006897; P:endocytosis; IEA:UniProtKB-KW.
515Q96RU3    617   FNBP1_HUMAN Formin-binding protein 1 OS=Homo ...611.6     35     31     52GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell.::GO:0016023; C:cytoplasmic membrane-bounded vesicle; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005764; C:lysosome; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0042802; F:identical protein binding; IPI:IntAct.::GO:0008289; F:lipid binding; IEA:UniProtKB-KW.
GO:0006897; P:endocytosis; IEA:UniProtKB-KW.
516P38822    633   BZZ1_YEAST Protein BZZ1 OS=Saccharomyces cere...541.6     35     28     56GO:0030479; C:actin cortical patch; IDA:SGD.::GO:0043332; C:mating projection tip; IDA:SGD.
GO:0005515; F:protein binding; IPI:IntAct.
GO:0007015; P:actin filament organization; IPI:SGD.::GO:0006897; P:endocytosis; IGI:SGD.::GO:0009651; P:response to salt stress; IGI:SGD.
517B5DFQ4    759   RHG26_XENTR Rho GTPase-activating protein 26 ...521.8     35     38     48GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell.
GO:0008093; F:cytoskeletal adaptor activity; IEA:InterPro.::GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0017124; F:SH3 domain binding; IEA:InterPro.
GO:0046847; P:filopodium assembly; IEA:InterPro.::GO:0007165; P:signal transduction; IEA:InterPro.
518Q9DC07    270   LNEBL_MOUSE LIM zinc-binding domain-containin...501.8     34.3     28     60
GO:0008270; F:zinc ion binding; IEA:InterPro.
519Q9JHL4    436   DBNL_RAT Drebrin-like protein OS=Rattus norve...561.8     34.7     34     55GO:0005938; C:cell cortex; ISS:UniProtKB.::GO:0030027; C:lamellipodium; ISS:UniProtKB.::GO:0014069; C:postsynaptic density; IDA:RGD.
GO:0006897; P:endocytosis; IEA:UniProtKB-KW.::GO:0016601; P:Rac protein signal transduction; ISS:UniProtKB.
520Q8WV41    574   SNX33_HUMAN Sorting nexin-33 OS=Homo sapiens ...531.9     34.7     30     62
GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0007154; P:cell communication; IEA:InterPro.
521A1X283    911   SPD2B_HUMAN SH3 and PX domain-containing prot...681.9     34.7     24     49GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0042995; C:cell projection; IEA:UniProtKB-KW.::GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0002102; C:podosome; ISS:UniProtKB.
GO:0080025; F:phosphatidylinositol-3,5-bisphosphate binding; ISS:UniProtKB.::GO:0032266; F:phosphatidylinositol-3-phosphate binding; ISS:UniProtKB.::GO:0010314; F:phosphatidylinositol-5-phosphate binding; ISS:UniProtKB.::GO:0042169; F:SH2 domain binding; ISS:UniProtKB.
GO:0060612; P:adipose tissue development; ISS:UniProtKB.::GO:0060348; P:bone development; IMP:UniProtKB.::GO:0007154; P:cell communication; IEA:InterPro.::GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0022617; P:extracellular matrix disassembly; IMP:UniProtKB.::GO:0001654; P:eye development; IMP:UniProtKB.::GO:0007507; P:heart development; IMP:UniProtKB.::GO:0071800; P:podosome assembly; ISS:UniProtKB.::GO:0072657; P:protein localization in membrane; IDA:UniProtKB.::GO:0006801; P:superoxide metabolic process; IDA:UniProtKB.
522Q39H30    972   IF2_BURS3 Translation initiation factor IF-2 ...801.9     34.7     35     44GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.::GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW.
523Q4WUG9    288   SHO1_ASPFU High osmolarity signaling protein ...532     34.3     36     57GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0006950; P:response to stress; IEA:UniProtKB-KW.
524B0Y3Z4    288   SHO1_ASPFC High osmolarity signaling protein ...532     34.3     36     57GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0006950; P:response to stress; IEA:UniProtKB-KW.
525P20929    6669   NEBU_HUMAN Nebulin OS=Homo sapiens (Human). G...502     35     32     56GO:0015629; C:actin cytoskeleton; TAS:ProtInc.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0030018; C:Z disc; IDA:UniProtKB.
GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0008307; F:structural constituent of muscle; TAS:ProtInc.
GO:0030049; P:muscle filament sliding; TAS:Reactome.::GO:0007517; P:muscle organ development; TAS:ProtInc.::GO:0030832; P:regulation of actin filament length; NAS:UniProtKB.::GO:0007525; P:somatic muscle development; NAS:UniProtKB.
526Q62418    436   DBNL_MOUSE Drebrin-like protein OS=Mus muscul...562     34.7     34     55GO:0005938; C:cell cortex; IDA:MGI.::GO:0030027; C:lamellipodium; IDA:UniProtKB.::GO:0001726; C:ruffle; IDA:UniProtKB.
GO:0051015; F:actin filament binding; IDA:UniProtKB.::GO:0019904; F:protein domain specific binding; IDA:MGI.
GO:0006897; P:endocytosis; IEA:UniProtKB-KW.::GO:0016601; P:Rac protein signal transduction; IDA:MGI.
527A2AAY5    908   SPD2B_MOUSE SH3 and PX domain-containing prot...682.1     34.7     24     49GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0042995; C:cell projection; IEA:UniProtKB-KW.::GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0002102; C:podosome; IDA:UniProtKB.
GO:0080025; F:phosphatidylinositol-3,5-bisphosphate binding; IDA:UniProtKB.::GO:0032266; F:phosphatidylinositol-3-phosphate binding; IMP:UniProtKB.::GO:0070273; F:phosphatidylinositol-4-phosphate binding; IDA:UniProtKB.::GO:0010314; F:phosphatidylinositol-5-phosphate binding; IDA:UniProtKB.::GO:0042169; F:SH2 domain binding; IDA:UniProtKB.
GO:0060612; P:adipose tissue development; IMP:UniProtKB.::GO:0060348; P:bone development; IMP:UniProtKB.::GO:0007154; P:cell communication; IEA:InterPro.::GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0001654; P:eye development; IMP:UniProtKB.::GO:0007507; P:heart development; IMP:UniProtKB.::GO:0071800; P:podosome assembly; IMP:UniProtKB.::GO:0045600; P:positive regulation of fat cell differentiation; IMP:UniProtKB.::GO:0072657; P:protein localization in membrane; ISS:UniProtKB.::GO:0006801; P:superoxide metabolic process; ISS:UniProtKB.
528A7F1F4    317   SHO1_SCLS1 High osmolarity signaling protein ...752.2     34.3     32     51GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0006950; P:response to stress; IEA:UniProtKB-KW.
529B8R1V5    299   SHO1_CLALS High osmolarity signaling protein ...762.2     34.3     30     51GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0006950; P:response to stress; IEA:UniProtKB-KW.
530C4Y1G1    299   SHO1_CLAL4 High osmolarity signaling protein ...762.2     34.3     30     51GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0006950; P:response to stress; IEA:UniProtKB-KW.
531A1DEZ0    288   SHO1_NEOFI High osmolarity signaling protein ...532.2     34.3     36     57GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0006950; P:response to stress; IEA:UniProtKB-KW.
532Q00013    466   EM55_HUMAN 55 kDa erythrocyte membrane protei...392.5     34.3     46     59GO:0005887; C:integral to plasma membrane; TAS:ProtInc.::GO:0005624; C:membrane fraction; TAS:ProtInc.::GO:0032420; C:stereocilium; IEA:UniProtKB-SubCell.
GO:0004385; F:guanylate kinase activity; TAS:ProtInc.::GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0090022; P:regulation of neutrophil chemotaxis; ISS:UniProtKB.::GO:0007165; P:signal transduction; TAS:ProtInc.
533Q5RDW4    466   EM55_PONAB 55 kDa erythrocyte membrane protei...392.5     34.3     46     59GO:0016020; C:membrane; IEA:UniProtKB-SubCell.::GO:0032420; C:stereocilium; IEA:UniProtKB-SubCell.
GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
GO:0090022; P:regulation of neutrophil chemotaxis; ISS:UniProtKB.
534Q2US45    1261   MYO1_ASPOR Myosin-1 OS=Aspergillus oryzae (st...372.5     34.7     43     57GO:0030479; C:actin cortical patch; IEA:UniProtKB-SubCell.::GO:0016459; C:myosin complex; IEA:UniProtKB-KW.
GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003774; F:motor activity; IEA:InterPro.
535A9CB74    466   EM55_PAPAN 55 kDa erythrocyte membrane protei...392.6     34.3     46     59GO:0016020; C:membrane; IEA:UniProtKB-SubCell.::GO:0032420; C:stereocilium; IEA:UniProtKB-SubCell.
GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
GO:0090022; P:regulation of neutrophil chemotaxis; ISS:UniProtKB.
536Q17QN6    466   EM55_BOVIN 55 kDa erythrocyte membrane protei...282.7     34.3     54     61GO:0016020; C:membrane; IEA:UniProtKB-SubCell.::GO:0032420; C:stereocilium; IEA:UniProtKB-SubCell.
GO:0090022; P:regulation of neutrophil chemotaxis; ISS:UniProtKB.
537Q922K9    512   FRK_MOUSE Tyrosine-protein kinase FRK OS=Mus ...602.7     34.3     32     47GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC.
538Q9BVN2    902   RUSC1_HUMAN RUN and SH3 domain-containing pro...522.8     34.3     29     52GO:0005737; C:cytoplasm; IDA:HPA.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005070; F:SH3/SH2 adaptor activity; TAS:ProtInc.
539E5AD87    336   SHO1_LEPMJ High osmolarity signaling protein ...402.8     33.9     40     63GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0006950; P:response to stress; IEA:UniProtKB-KW.
540Q7TNF8    1846   RIMB1_MOUSE Peripheral-type benzodiazepine re...683.1     34.3     31     50GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.
541P70290    466   EM55_MOUSE 55 kDa erythrocyte membrane protei...393.1     33.9     46     59GO:0030863; C:cortical cytoskeleton; IDA:MGI.::GO:0016020; C:membrane; IDA:MGI.::GO:0032420; C:stereocilium; IEA:UniProtKB-SubCell.
GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0090022; P:regulation of neutrophil chemotaxis; IMP:UniProtKB.
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