Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YHR016C
Length:
468
Number of sequences:
5887
Description:
YHR016C YSC84 SGDID:S000001058, Chr VIII from 138240-136881,138455-138409, Genome Release 64-1-1, reverse complement, Verified ORF, "Actin-binding protein involved in bundling of actin filaments and endocytosis of actin cortical patches; activity stimulated by Las17p; contains SH3 domain similar to Rvs167p"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
481P34416    335   LASP1_CAEEL LIM and SH3 domain protein F42H10...530.87     35.4     34     58
GO:0008270; F:zinc ion binding; IEA:InterPro.
482Q6BVC2    304   SHO1_DEBHA High osmolarity signaling protein ...570.88     35.4     35     58GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0006950; P:response to stress; IEA:UniProtKB-KW.
483Q5ZMW5    760   RHG26_CHICK Rho GTPase-activating protein 26 ...520.95     35.8     38     48GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell.
GO:0008093; F:cytoskeletal adaptor activity; IEA:InterPro.::GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0017124; F:SH3 domain binding; IEA:InterPro.
GO:0046847; P:filopodium assembly; IEA:InterPro.::GO:0007165; P:signal transduction; IEA:InterPro.
484O94478    420   MU137_SCHPO Meiotically up-regulated gene 137...810.96     35.4     28     43GO:0032153; C:cell division site; IDA:PomBase.::GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.
GO:0007126; P:meiosis; IEP:PomBase.
485Q96JP2    1530   MY15B_HUMAN Putative unconventional myosin-XV...520.96     35.8     31     58GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016459; C:myosin complex; IEA:InterPro.
GO:0005524; F:ATP binding; IEA:InterPro.::GO:0003774; F:motor activity; IEA:InterPro.
486Q6CHN0    1136   SLA1_YARLI Actin cytoskeleton-regulatory comp...530.97     35.8     40     55GO:0030479; C:actin cortical patch; IEA:UniProtKB-SubCell.::GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0042802; F:identical protein binding; IEA:InterPro.::GO:0030674; F:protein binding, bridging; IEA:InterPro.::GO:0043130; F:ubiquitin binding; IEA:InterPro.
GO:0006897; P:endocytosis; IEA:UniProtKB-KW.
487Q8BYZ1    367   ABI3_MOUSE ABI gene family member 3 OS=Mus mu...551     35.4     31     53GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
488Q5ZJ00    468   EM55_CHICK 55 kDa erythrocyte membrane protei...281     35.4     54     64GO:0016020; C:membrane; IEA:UniProtKB-SubCell.::GO:0032420; C:stereocilium; IEA:UniProtKB-SubCell.
GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
489Q80TY0    616   FNBP1_MOUSE Formin-binding protein 1 OS=Mus m...601.1     35.4     32     55GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell.::GO:0016023; C:cytoplasmic membrane-bounded vesicle; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005764; C:lysosome; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0008289; F:lipid binding; IEA:UniProtKB-KW.
GO:0006897; P:endocytosis; IEA:UniProtKB-KW.
490Q8R511    616   FNBP1_RAT Formin-binding protein 1 OS=Rattus ...601.1     35.4     32     55GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell.::GO:0016023; C:cytoplasmic membrane-bounded vesicle; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005764; C:lysosome; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0008289; F:lipid binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0006897; P:endocytosis; IEA:UniProtKB-KW.::GO:0007399; P:nervous system development; IDA:RGD.
491A2R5J1    1270   MYO1_ASPNC Myosin-1 OS=Aspergillus niger (str...561.1     35.8     32     50GO:0030479; C:actin cortical patch; IEA:UniProtKB-SubCell.::GO:0016459; C:myosin complex; IEA:UniProtKB-KW.
GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003774; F:motor activity; IEA:InterPro.
492P26019    1488   DPOLA_DROME DNA polymerase alpha catalytic su...601.1     35.8     25     53GO:0005658; C:alpha DNA polymerase:primase complex; IDA:FlyBase.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003887; F:DNA-directed DNA polymerase activity; IDA:FlyBase.::GO:0004527; F:exonuclease activity; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0001882; F:nucleoside binding; IEA:InterPro.::GO:0000166; F:nucleotide binding; IEA:InterPro.
GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0006260; P:DNA replication; IDA:FlyBase.
493Q4VAA7    574   SNX33_MOUSE Sorting nexin-33 OS=Mus musculus ...531.2     35.4     30     62
GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.
GO:0007154; P:cell communication; IEA:InterPro.
494Q9H6Q3    261   SLAP2_HUMAN Src-like-adapter 2 OS=Homo sapien...691.2     35     30     51GO:0016023; C:cytoplasmic membrane-bounded vesicle; IEA:UniProtKB-SubCell.::GO:0010008; C:endosome membrane; NAS:UniProtKB.::GO:0005886; C:plasma membrane; TAS:UniProtKB.
GO:0047485; F:protein N-terminus binding; IPI:UniProtKB.::GO:0005070; F:SH3/SH2 adaptor activity; IDA:UniProtKB.
GO:0050851; P:antigen receptor-mediated signaling pathway; TAS:UniProtKB.::GO:0019724; P:B cell mediated immunity; TAS:UniProtKB.::GO:0030522; P:intracellular receptor mediated signaling pathway; TAS:UniProtKB.::GO:0050869; P:negative regulation of B cell activation; TAS:UniProtKB.::GO:0050849; P:negative regulation of calcium-mediated signaling; IDA:UniProtKB.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.::GO:0042110; P:T cell activation; TAS:UniProtKB.
495A6H7G2    423   DBNL_BOVIN Drebrin-like protein OS=Bos taurus...561.2     35.4     34     55GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0030027; C:lamellipodium; IEA:UniProtKB-SubCell.
GO:0006897; P:endocytosis; IEA:UniProtKB-KW.
496Q811P8    2089   RHG32_MOUSE Rho GTPase-activating protein 32 ...691.3     35.4     22     46GO:0015629; C:actin cytoskeleton; IDA:MGI.::GO:0005938; C:cell cortex; IDA:MGI.::GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.::GO:0014069; C:postsynaptic density; IEA:UniProtKB-SubCell.::GO:0045211; C:postsynaptic membrane; IEA:UniProtKB-KW.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.
GO:0007165; P:signal transduction; IEA:InterPro.
497Q80U40    1072   RIMB2_MOUSE RIMS-binding protein 2 OS=Mus mus...581.3     35.4     29     59GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0045202; C:synapse; IEA:UniProtKB-SubCell.
GO:0010923; P:negative regulation of phosphatase activity; ISS:UniProtKB.
498Q8QFX1    1325   RIMB2_CHICK RIMS-binding protein 2 OS=Gallus ...581.3     35.4     29     59GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0045202; C:synapse; IEA:UniProtKB-SubCell.
GO:0010923; P:negative regulation of phosphatase activity; ISS:UniProtKB.
499O15034    1052   RIMB2_HUMAN RIMS-binding protein 2 OS=Homo sa...581.3     35.4     29     59GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0045202; C:synapse; IEA:UniProtKB-SubCell.
GO:0010923; P:negative regulation of phosphatase activity; IDA:UniProtKB.
500A1C4A5    1253   MYO1_ASPCL Myosin-1 OS=3887 / NRRL 1). GN=myo...331.3     35.4     39     64GO:0030479; C:actin cortical patch; IEA:UniProtKB-SubCell.::GO:0016459; C:myosin complex; IEA:UniProtKB-KW.
GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003774; F:motor activity; IEA:InterPro.
501Q8N1I0    1966   DOCK4_HUMAN Dedicator of cytokinesis protein ...571.3     35.4     33     54GO:0005829; C:cytosol; IDA:UniProtKB.::GO:0012505; C:endomembrane system; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IDA:UniProtKB.::GO:0032420; C:stereocilium; ISS:HGNC.
GO:0005525; F:GTP binding; IEA:InterPro.::GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW.::GO:0030165; F:PDZ domain binding; IPI:HGNC.::GO:0030675; F:Rac GTPase activator activity; IDA:HGNC.::GO:0048365; F:Rac GTPase binding; IDA:HGNC.::GO:0030971; F:receptor tyrosine kinase binding; IPI:UniProtKB.::GO:0017124; F:SH3 domain binding; IEA:UniProtKB-KW.
GO:0060326; P:cell chemotaxis; IMP:UniProtKB.
502Q8R4L0    259   SLAP2_MOUSE Src-like-adapter 2 OS=Mus musculu...561.4     34.7     41     59GO:0016023; C:cytoplasmic membrane-bounded vesicle; IDA:MGI.::GO:0005770; C:late endosome; IDA:MGI.::GO:0005886; C:plasma membrane; IDA:MGI.
GO:0047485; F:protein N-terminus binding; ISS:UniProtKB.::GO:0005070; F:SH3/SH2 adaptor activity; ISS:UniProtKB.
GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0042110; P:T cell activation; IDA:MGI.
503A7KAX9    2087   RHG32_HUMAN Rho GTPase-activating protein 32 ...691.4     35.4     22     46GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell.::GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.::GO:0014069; C:postsynaptic density; IEA:UniProtKB-SubCell.::GO:0045211; C:postsynaptic membrane; IEA:UniProtKB-KW.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.
504P59764    1978   DOCK4_MOUSE Dedicator of cytokinesis protein ...571.4     35.4     33     54GO:0005829; C:cytosol; ISS:UniProtKB.::GO:0012505; C:endomembrane system; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; ISS:UniProtKB.::GO:0032420; C:stereocilium; IDA:HGNC.
GO:0005525; F:GTP binding; IEA:InterPro.::GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW.::GO:0017124; F:SH3 domain binding; IEA:UniProtKB-KW.
GO:0060326; P:cell chemotaxis; ISS:UniProtKB.
505Q9JIR1    1049   RIMB2_RAT RIMS-binding protein 2 OS=Rattus no...581.4     35.4     29     59GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0045202; C:synapse; IEA:UniProtKB-SubCell.
GO:0005515; F:protein binding; IPI:RGD.
GO:0010923; P:negative regulation of phosphatase activity; ISS:UniProtKB.
506Q8AXQ3    966   SH3B4_SERQU SH3 domain-binding protein 4 OS=S...701.4     35.4     31     47GO:0030136; C:clathrin-coated vesicle; IEA:UniProtKB-SubCell.::GO:0005905; C:coated pit; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0006897; P:endocytosis; IEA:UniProtKB-KW.
507Q6FTC4    353   SHO1_CANGA High osmolarity signaling protein ...551.5     34.7     29     62GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0006950; P:response to stress; IEA:UniProtKB-KW.
508A0K6X5    971   IF2_BURCH Translation initiation factor IF-2 ...801.5     35     35     44GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.::GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW.
509Q1BWS7    971   IF2_BURCA Translation initiation factor IF-2 ...801.5     35     35     44GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.::GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW.
510B1K0M0    971   IF2_BURCC Translation initiation factor IF-2 ...801.5     35     35     44GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.::GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW.
511Q08881    620   ITK_HUMAN Tyrosine-protein kinase ITK/TSK OS=...541.5     35     30     54GO:0005829; C:cytosol; TAS:Reactome.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IDA:UniProtKB.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0007202; P:activation of phospholipase C activity; ISS:UniProtKB.::GO:0002250; P:adaptive immune response; ISS:UniProtKB.::GO:0006968; P:cellular defense response; TAS:ProtInc.::GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0050852; P:T cell receptor signaling pathway; ISS:UniProtKB.
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