Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YHR016C
Length:
468
Number of sequences:
5887
Description:
YHR016C YSC84 SGDID:S000001058, Chr VIII from 138240-136881,138455-138409, Genome Release 64-1-1, reverse complement, Verified ORF, "Actin-binding protein involved in bundling of actin filaments and endocytosis of actin cortical patches; activity stimulated by Las17p; contains SH3 domain similar to Rvs167p"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
451Q5TCZ1    1133   SPD2A_HUMAN SH3 and PX domain-containing prot...523.2     34.3     29     56GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0042995; C:cell projection; IEA:UniProtKB-KW.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0002102; C:podosome; IDA:UniProtKB.
GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0007154; P:cell communication; IEA:InterPro.::GO:0006801; P:superoxide metabolic process; IDA:UniProtKB.
452Q9XVN3    769   IASPP_CAEEL Apoptotic enhancer 1 protein OS=C...510.34     37.4     31     53GO:0005634; C:nucleus; ISS:WormBase.
GO:0002039; F:p53 binding; IPI:WormBase.
GO:0006915; P:apoptotic process; IMP:WormBase.::GO:0043066; P:negative regulation of apoptotic process; IMP:WormBase.
453Q6Y5D8    786   RHG10_MOUSE Rho GTPase-activating protein 10 ...540.36     37     33     54GO:0005829; C:cytosol; IMP:UniProtKB.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0008093; F:cytoskeletal adaptor activity; IEA:InterPro.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005100; F:Rho GTPase activator activity; IPI:MGI.::GO:0017124; F:SH3 domain binding; IEA:InterPro.
GO:0007010; P:cytoskeleton organization; IMP:MGI.::GO:0046847; P:filopodium assembly; IEA:InterPro.::GO:0043066; P:negative regulation of apoptotic process; IMP:UniProtKB.::GO:0007165; P:signal transduction; IEA:InterPro.
454Q5RCJ1    601   CIP4_PONAB Cdc42-interacting protein 4 OS=Pon...570.37     37     32     60GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell.::GO:0042995; C:cell projection; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0005764; C:lysosome; IEA:UniProtKB-SubCell.::GO:0001891; C:phagocytic cup; IEA:UniProtKB-SubCell.
GO:0008289; F:lipid binding; IEA:UniProtKB-KW.
GO:0006897; P:endocytosis; IEA:UniProtKB-KW.
455Q15642    601   CIP4_HUMAN Cdc42-interacting protein 4 OS=Hom...570.39     37     32     60GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell.::GO:0042995; C:cell projection; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0005764; C:lysosome; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.::GO:0001891; C:phagocytic cup; IEA:UniProtKB-SubCell.
GO:0042802; F:identical protein binding; IPI:IntAct.::GO:0008289; F:lipid binding; IEA:UniProtKB-KW.
GO:0030036; P:actin cytoskeleton organization; NAS:UniProtKB.::GO:0006897; P:endocytosis; IEA:UniProtKB-KW.::GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.
456A1IGU3    676   ARH37_RAT Rho guanine nucleotide exchange fac...640.4     37     28     47GO:0005737; C:cytoplasm; IEA:InterPro.
GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro.
GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro.
457C5DE38    342   SHO1_LACTC High osmolarity signaling protein ...580.41     36.6     33     57GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0006950; P:response to stress; IEA:UniProtKB-KW.
458A1IGU4    676   ARH37_MOUSE Rho guanine nucleotide exchange f...640.44     37     28     47GO:0005737; C:cytoplasm; IEA:InterPro.
GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro.
GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro.
459Q6CAC5    300   SHO1_YARLI High osmolarity signaling protein ...550.44     36.2     40     53GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0006950; P:response to stress; IEA:UniProtKB-KW.
460Q62077    1302   PLCG1_MOUSE 1-phosphatidylinositol 4,5-bispho...510.46     37     35     59GO:0005829; C:cytosol; TAS:Reactome.::GO:0030027; C:lamellipodium; ISS:UniProtKB.::GO:0001726; C:ruffle; ISS:UniProtKB.
GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0035254; F:glutamate receptor binding; IPI:MGI.::GO:0004435; F:phosphatidylinositol phospholipase C activity; IEA:EC.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0030971; F:receptor tyrosine kinase binding; IPI:UniProtKB.::GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW.
GO:0071364; P:cellular response to epidermal growth factor stimulus; ISS:UniProtKB.::GO:0001701; P:in utero embryonic development; IMP:MGI.::GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0009395; P:phospholipid catabolic process; IEA:InterPro.::GO:0010634; P:positive regulation of epithelial cell migration; ISS:UniProtKB.::GO:0050852; P:T cell receptor signaling pathway; IDA:MGI.
461P97531    547   CIP4_RAT Cdc42-interacting protein 4 OS=Rattu...630.46     36.6     32     59GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell.::GO:0042995; C:cell projection; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0005764; C:lysosome; IEA:UniProtKB-SubCell.::GO:0001891; C:phagocytic cup; IEA:UniProtKB-SubCell.
GO:0008289; F:lipid binding; IEA:UniProtKB-KW.
GO:0006897; P:endocytosis; IEA:UniProtKB-KW.::GO:0042538; P:hyperosmotic salinity response; IDA:RGD.
462E7Q311    367   SHO1_YEASB High osmolarity signaling protein ...2010.47     36.6     25     42GO:0042995; C:cell projection; IEA:UniProtKB-SubCell.::GO:0005935; C:cellular bud neck; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0006950; P:response to stress; IEA:UniProtKB-KW.
463O74653    871   POB1_SCHPO Protein pob1 OS=Schizosaccharomyce...560.48     36.6     32     54GO:0051285; C:cell cortex of cell tip; IDA:PomBase.::GO:0032153; C:cell division site; IDA:PomBase.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
GO:0005543; F:phospholipid binding; IEA:InterPro.
GO:0000920; P:cytokinetic cell separation; IMP:PomBase.::GO:0008360; P:regulation of cell shape; IMP:PomBase.
464A1A4S6    786   RHG10_HUMAN Rho GTPase-activating protein 10 ...540.48     36.6     33     54GO:0005829; C:cytosol; TAS:Reactome.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0008093; F:cytoskeletal adaptor activity; IEA:InterPro.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0017124; F:SH3 domain binding; IEA:InterPro.
GO:0006915; P:apoptotic process; TAS:Reactome.::GO:0046847; P:filopodium assembly; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.
465Q08DP6    785   RHG10_BOVIN Rho GTPase-activating protein 10 ...540.5     36.6     33     54GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0008093; F:cytoskeletal adaptor activity; IEA:InterPro.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0017124; F:SH3 domain binding; IEA:InterPro.
GO:0046847; P:filopodium assembly; IEA:InterPro.::GO:0007165; P:signal transduction; IEA:InterPro.
466Q7ZXQ9    447   DBNLA_XENLA Drebrin-like protein A OS=Xenopus...560.5     36.6     36     55GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0030027; C:lamellipodium; IEA:UniProtKB-SubCell.
GO:0003779; F:actin binding; IEA:UniProtKB-KW.
467P10686    1290   PLCG1_RAT 1-phosphatidylinositol 4,5-bisphosp...510.5     36.6     35     59GO:0030027; C:lamellipodium; ISS:UniProtKB.::GO:0005886; C:plasma membrane; TAS:Reactome.::GO:0001726; C:ruffle; ISS:UniProtKB.
GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0005158; F:insulin receptor binding; IDA:RGD.::GO:0004435; F:phosphatidylinositol phospholipase C activity; IEA:EC.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0051219; F:phosphoprotein binding; IPI:RGD.::GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW.
GO:0006816; P:calcium ion transport; IMP:RGD.::GO:0071364; P:cellular response to epidermal growth factor stimulus; ISS:UniProtKB.::GO:0032959; P:inositol trisphosphate biosynthetic process; IMP:RGD.::GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0009395; P:phospholipid catabolic process; IEA:InterPro.::GO:0032236; P:positive regulation of calcium ion transport via store-operated calcium channel activity; IMP:RGD.::GO:0010634; P:positive regulation of epithelial cell migration; IMP:RGD.::GO:0009306; P:protein secretion; IMP:RGD.::GO:0009629; P:response to gravity; IEP:RGD.::GO:0042542; P:response to hydrogen peroxide; IEP:RGD.::GO:0043278; P:response to morphine; IEP:RGD.::GO:0010243; P:response to organic nitrogen; IEP:RGD.
468B2RY04    1868   DOCK5_MOUSE Dedicator of cytokinesis protein ...570.51     37     32     54GO:0005737; C:cytoplasm; IDA:UniProtKB.
GO:0005525; F:GTP binding; IEA:InterPro.::GO:0051020; F:GTPase binding; IEA:InterPro.::GO:0005085; F:guanyl-nucleotide exchange factor activity; IDA:UniProtKB.
469C7GKW5    367   SHO1_YEAS2 High osmolarity signaling protein ...420.51     36.2     38     67GO:0042995; C:cell projection; IEA:UniProtKB-SubCell.::GO:0005935; C:cellular bud neck; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0006950; P:response to stress; IEA:UniProtKB-KW.
470Q1LYG0    1119   SPD2A_DANRE SH3 and PX domain-containing prot...511.7     35     27     59GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0042995; C:cell projection; IEA:UniProtKB-KW.::GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0002102; C:podosome; ISS:UniProtKB.
GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.
GO:0007154; P:cell communication; IEA:InterPro.::GO:0006801; P:superoxide metabolic process; ISS:UniProtKB.
471O76041    1014   NEBL_HUMAN Nebulette OS=Homo sapiens (Human)....960.56     36.6     22     50GO:0001725; C:stress fiber; IDA:UniProtKB.::GO:0030018; C:Z disc; IDA:UniProtKB.
GO:0051015; F:actin filament binding; IDA:UniProtKB.::GO:0031005; F:filamin binding; IPI:UniProtKB.::GO:0008307; F:structural constituent of muscle; NAS:UniProtKB.::GO:0005523; F:tropomyosin binding; IPI:UniProtKB.
GO:0071691; P:cardiac muscle thin filament assembly; IMP:UniProtKB.
472Q9P2A4    366   ABI3_HUMAN ABI gene family member 3 OS=Homo s...550.57     36.2     31     53GO:0005737; C:cytoplasm; NAS:UniProtKB.::GO:0030027; C:lamellipodium; IDA:MGI.
GO:0005515; F:protein binding; IPI:IntAct.
GO:0006928; P:cellular component movement; NAS:UniProtKB.::GO:0030334; P:regulation of cell migration; IDA:MGI.
473Q92608    1830   DOCK2_HUMAN Dedicator of cytokinesis protein ...570.58     36.6     32     54GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0012505; C:endomembrane system; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IDA:HPA.::GO:0005886; C:plasma membrane; IDA:HPA.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0005525; F:GTP binding; IEA:InterPro.::GO:0051020; F:GTPase binding; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0030676; F:Rac guanyl-nucleotide exchange factor activity; IDA:UniProtKB.::GO:0042608; F:T cell receptor binding; IDA:UniProtKB.
GO:0030036; P:actin cytoskeleton organization; TAS:UniProtKB.::GO:0050690; P:regulation of defense response to virus by virus; TAS:Reactome.::GO:0016032; P:viral reproduction; TAS:Reactome.
474Q75JD4    533   Y1676_DICDI SH3 and FCH domain-containing pro...530.64     36.2     28     58
475Q8CIQ7    2027   DOCK3_MOUSE Dedicator of cytokinesis protein ...650.67     36.6     32     52GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:InterPro.::GO:0051020; F:GTPase binding; IEA:InterPro.::GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW.::GO:0017124; F:SH3 domain binding; IEA:UniProtKB-KW.
476O89032    1124   SPD2A_MOUSE SH3 and PX domain-containing prot...523.2     34.3     29     56GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0042995; C:cell projection; IEA:UniProtKB-KW.::GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0002102; C:podosome; ISS:UniProtKB.
GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0007154; P:cell communication; IEA:InterPro.
477Q5U4T3    771   RHG26_XENLA Rho GTPase-activating protein 26 ...520.72     36.2     38     48GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell.
GO:0008093; F:cytoskeletal adaptor activity; IEA:InterPro.::GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0017124; F:SH3 domain binding; IEA:InterPro.
GO:0046847; P:filopodium assembly; IEA:InterPro.::GO:0007165; P:signal transduction; IEA:InterPro.
478O14259    415   YFP2_SCHPO SH3 domain-containing protein C7D4...560.75     35.8     32     50GO:0005829; C:cytosol; IDA:PomBase.
GO:0005515; F:protein binding; IPI:PomBase.
GO:0034613; P:cellular protein localization; IGI:PomBase.::GO:2000157; P:negative regulation of ubiquitin-specific protease activity; IMP:PomBase.
479Q8N2Y8    1516   RUSC2_HUMAN Iporin OS=Homo sapiens (Human). G...630.76     36.2     33     48GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.
480Q8WZX5    1072   XRN2_NEUCR 5'-3' exoribonuclease 2 OS=1257 / ...1650.81     36.2     23     37GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0004534; F:5'-3' exoribonuclease activity; IEA:InterPro.::GO:0003676; F:nucleic acid binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.::GO:0006353; P:transcription termination, DNA-dependent; IEA:UniProtKB-KW.
481P34416    335   LASP1_CAEEL LIM and SH3 domain protein F42H10...530.87     35.4     34     58
GO:0008270; F:zinc ion binding; IEA:InterPro.
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