rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
421 | A7TI28 | 358 | SHO1_VANPO High osmolarity signaling protein ... | 58 | 0.12 | 38.5 | 36 | 64 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006950; P:response to stress; IEA:UniProtKB-KW. | 422 | P15891 | 592 | ABP1_YEAST Actin-binding protein OS=Saccharom... | 58 | 0.12 | 38.5 | 34 | 57 | GO:0030479; C:actin cortical patch; IDA:SGD.::GO:0043332; C:mating projection tip; IDA:SGD. | | | | | | | | | | GO:0051015; F:actin filament binding; IDA:SGD. | | | | | | | | | | GO:0000147; P:actin cortical patch assembly; IMP:SGD.::GO:0008104; P:protein localization; IMP:SGD. | 423 | Q66L42 | 940 | M3K10_MOUSE Mitogen-activated protein kinase ... | 60 | 0.12 | 38.5 | 30 | 57 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004709; F:MAP kinase kinase kinase activity; IEA:EC.::GO:0003714; F:transcription corepressor activity; IDA:MGI. | | | | | | | | | | GO:0045892; P:negative regulation of transcription, DNA-dependent; IDA:MGI. | 424 | Q6ZQ82 | 814 | RHG26_MOUSE Rho GTPase-activating protein 26 ... | 65 | 0.12 | 38.5 | 37 | 49 | GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008093; F:cytoskeletal adaptor activity; IEA:InterPro.::GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0017124; F:SH3 domain binding; IEA:InterPro. | | | | | | | | | | GO:0046847; P:filopodium assembly; IEA:InterPro.::GO:0007165; P:signal transduction; IEA:InterPro. | 425 | P34258 | 493 | YKA7_CAEEL Uncharacterized protein B0303.7 OS... | 61 | 4.2 | 33.5 | 31 | 51 | | | | | | | | | | | | | | | | | | | | | | 426 | Q8VDG6 | 1002 | M3KL4_MOUSE Mitogen-activated protein kinase ... | 52 | 0.13 | 38.5 | 29 | 56 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004709; F:MAP kinase kinase kinase activity; IEA:EC.::GO:0004713; F:protein tyrosine kinase activity; IEA:InterPro. | | | | | | | | | | | 427 | Q6NRL2 | 550 | SNX33_XENLA Sorting nexin-33 OS=Xenopus laevi... | 57 | 0.14 | 38.1 | 37 | 56 | | | | | | | | | | | GO:0035091; F:phosphatidylinositol binding; IEA:InterPro. | | | | | | | | | | GO:0007154; P:cell communication; IEA:InterPro. | 428 | Q6GPD0 | 1940 | RHG32_XENLA Rho GTPase-activating protein 32 ... | 69 | 0.15 | 38.5 | 23 | 49 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0035091; F:phosphatidylinositol binding; IEA:InterPro. | | | | | | | | | | GO:0007165; P:signal transduction; IEA:InterPro. | 429 | Q9H7D0 | 1870 | DOCK5_HUMAN Dedicator of cytokinesis protein ... | 54 | 0.16 | 38.5 | 31 | 56 | GO:0005737; C:cytoplasm; ISS:UniProtKB. | | | | | | | | | | GO:0005525; F:GTP binding; IEA:InterPro.::GO:0051020; F:GTPase binding; IEA:InterPro.::GO:0005085; F:guanyl-nucleotide exchange factor activity; ISS:UniProtKB. | | | | | | | | | | | 430 | P32790 | 1244 | SLA1_YEAST Actin cytoskeleton-regulatory comp... | 58 | 0.36 | 37.4 | 33 | 59 | GO:0030479; C:actin cortical patch; IDA:SGD.::GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.::GO:0043332; C:mating projection tip; IDA:SGD.::GO:0005634; C:nucleus; IDA:SGD.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0042802; F:identical protein binding; IEA:InterPro.::GO:0030674; F:protein binding, bridging; IPI:SGD.::GO:0043130; F:ubiquitin binding; IDA:SGD. | | | | | | | | | | GO:0000147; P:actin cortical patch assembly; TAS:SGD.::GO:0006897; P:endocytosis; IPI:SGD.::GO:0031505; P:fungal-type cell wall organization; TAS:SGD. | 431 | A6ZKU1 | 1244 | SLA1_YEAS7 Actin cytoskeleton-regulatory comp... | 58 | 0.37 | 37.4 | 33 | 59 | GO:0030479; C:actin cortical patch; IEA:UniProtKB-SubCell.::GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0042802; F:identical protein binding; IEA:InterPro.::GO:0030674; F:protein binding, bridging; IEA:InterPro.::GO:0043130; F:ubiquitin binding; IEA:InterPro. | | | | | | | | | | GO:0006897; P:endocytosis; IEA:UniProtKB-KW. | 432 | A6ZR73 | 367 | SHO1_YEAS7 High osmolarity signaling protein ... | 201 | 0.19 | 37.7 | 25 | 42 | GO:0042995; C:cell projection; IEA:UniProtKB-SubCell.::GO:0005935; C:cellular bud neck; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006950; P:response to stress; IEA:UniProtKB-KW. | 433 | E7RAI2 | 282 | SHO1_PICAD High osmolarity signaling protein ... | 42 | 0.21 | 37.4 | 40 | 67 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006950; P:response to stress; IEA:UniProtKB-KW. | 434 | E3RIP0 | 309 | SHO1_PYRTT High osmolarity signaling protein ... | 79 | 0.21 | 37.4 | 30 | 51 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006950; P:response to stress; IEA:UniProtKB-KW. | 435 | Q9NZQ3 | 722 | SPN90_HUMAN NCK-interacting protein with SH3 ... | 53 | 0.22 | 37.7 | 34 | 51 | GO:0005882; C:intermediate filament; NAS:UniProtKB.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008092; F:cytoskeletal protein binding; NAS:UniProtKB.::GO:0017124; F:SH3 domain binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007010; P:cytoskeleton organization; NAS:UniProtKB.::GO:0006607; P:NLS-bearing substrate import into nucleus; TAS:ProtInc.::GO:0007165; P:signal transduction; TAS:ProtInc. | 436 | Q8CJ53 | 603 | CIP4_MOUSE Cdc42-interacting protein 4 OS=Mus... | 57 | 0.24 | 37.7 | 32 | 60 | GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell.::GO:0042995; C:cell projection; IEA:UniProtKB-KW.::GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0005764; C:lysosome; IEA:UniProtKB-SubCell.::GO:0005874; C:microtubule; TAS:MGI.::GO:0001891; C:phagocytic cup; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008289; F:lipid binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006897; P:endocytosis; IEA:UniProtKB-KW. | 437 | Q9R144 | 448 | ANM2_MOUSE Protein arginine N-methyltransfera... | 51 | 0.24 | 37.4 | 33 | 57 | GO:0005829; C:cytosol; ISS:BHF-UCL.::GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0050681; F:androgen receptor binding; ISS:BHF-UCL.::GO:0008013; F:beta-catenin binding; IPI:UniProtKB.::GO:0030331; F:estrogen receptor binding; ISS:UniProtKB.::GO:0008469; F:histone-arginine N-methyltransferase activity; IDA:UniProtKB.::GO:0042975; F:peroxisome proliferator activated receptor binding; ISS:BHF-UCL.::GO:0033142; F:progesterone receptor binding; ISS:BHF-UCL.::GO:0042803; F:protein homodimerization activity; ISS:BHF-UCL.::GO:0042974; F:retinoic acid receptor binding; ISS:BHF-UCL.::GO:0046966; F:thyroid hormone receptor binding; ISS:BHF-UCL. | | | | | | | | | | GO:0048588; P:developmental cell growth; IMP:UniProtKB.::GO:0006917; P:induction of apoptosis; ISS:UniProtKB.::GO:0033210; P:leptin-mediated signaling pathway; NAS:BHF-UCL.::GO:2000134; P:negative regulation of G1/S transition of mitotic cell cycle; IMP:UniProtKB.::GO:0043433; P:negative regulation of sequence-specific DNA binding transcription factor activity; IMP:UniProtKB.::GO:0045892; P:negative regulation of transcription, DNA-dependent; IDA:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0060765; P:regulation of androgen receptor signaling pathway; ISS:UniProtKB.::GO:0042516; P:regulation of tyrosine phosphorylation of Stat3 protein; NAS:BHF-UCL.::GO:0001666; P:response to hypoxia; IDA:BHF-UCL. | 438 | Q751J2 | 330 | SHO1_ASHGO High osmolarity signaling protein ... | 58 | 0.26 | 37 | 34 | 59 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006950; P:response to stress; IEA:UniProtKB-KW. | 439 | A8MVU1 | 366 | NCF1C_HUMAN Putative neutrophil cytosol facto... | 78 | 0.27 | 37.4 | 28 | 51 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.::GO:0016175; F:superoxide-generating NADPH oxidase activity; IEA:InterPro. | | | | | | | | | | GO:0007154; P:cell communication; IEA:InterPro. | 440 | B3LRN4 | 367 | SHO1_YEAS1 High osmolarity signaling protein ... | 201 | 0.28 | 37 | 25 | 42 | GO:0042995; C:cell projection; IEA:UniProtKB-SubCell.::GO:0005935; C:cellular bud neck; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006950; P:response to stress; IEA:UniProtKB-KW. | 441 | E7QE10 | 367 | SHO1_YEASZ High osmolarity signaling protein ... | 201 | 0.29 | 37 | 25 | 42 | GO:0042995; C:cell projection; IEA:UniProtKB-SubCell.::GO:0005935; C:cellular bud neck; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006950; P:response to stress; IEA:UniProtKB-KW. | 442 | E7LTJ6 | 367 | SHO1_YEASV High osmolarity signaling protein ... | 201 | 0.29 | 37 | 25 | 42 | GO:0042995; C:cell projection; IEA:UniProtKB-SubCell.::GO:0005935; C:cellular bud neck; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006950; P:response to stress; IEA:UniProtKB-KW. | 443 | E7KMS3 | 367 | SHO1_YEASL High osmolarity signaling protein ... | 201 | 0.29 | 37 | 25 | 42 | GO:0042995; C:cell projection; IEA:UniProtKB-SubCell.::GO:0005935; C:cellular bud neck; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006950; P:response to stress; IEA:UniProtKB-KW. | 444 | E7KBW4 | 367 | SHO1_YEASA High osmolarity signaling protein ... | 201 | 0.29 | 37 | 25 | 42 | GO:0042995; C:cell projection; IEA:UniProtKB-SubCell.::GO:0005935; C:cellular bud neck; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006950; P:response to stress; IEA:UniProtKB-KW. | 445 | B5VHP4 | 367 | SHO1_YEAS6 High osmolarity signaling protein ... | 201 | 0.29 | 37 | 25 | 42 | GO:0042995; C:cell projection; IEA:UniProtKB-SubCell.::GO:0005935; C:cellular bud neck; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006950; P:response to stress; IEA:UniProtKB-KW. | 446 | Q6GM14 | 376 | DBNLB_XENLA Drebrin-like protein B OS=Xenopus... | 56 | 0.29 | 37 | 36 | 55 | GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0030027; C:lamellipodium; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW. | | | | | | | | | | | 447 | Q8C3J5 | 1828 | DOCK2_MOUSE Dedicator of cytokinesis protein ... | 57 | 0.3 | 37.4 | 32 | 54 | GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0012505; C:endomembrane system; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005525; F:GTP binding; IEA:InterPro.::GO:0051020; F:GTPase binding; IEA:InterPro.::GO:0030675; F:Rac GTPase activator activity; IMP:MGI.::GO:0030676; F:Rac guanyl-nucleotide exchange factor activity; ISS:UniProtKB.::GO:0042608; F:T cell receptor binding; ISS:UniProtKB. | | | | | | | | | | GO:0046633; P:alpha-beta T cell proliferation; IMP:MGI.::GO:0006935; P:chemotaxis; IMP:MGI.::GO:0007010; P:cytoskeleton organization; IDA:MGI.::GO:0001768; P:establishment of T cell polarity; IMP:MGI.::GO:0001771; P:immunological synapse formation; IMP:MGI.::GO:0001766; P:membrane raft polarization; IMP:MGI.::GO:0045060; P:negative thymic T cell selection; IMP:MGI.::GO:0035022; P:positive regulation of Rac protein signal transduction; IC:MGI.::GO:0045059; P:positive thymic T cell selection; IMP:MGI. | 448 | P40073 | 367 | SHO1_YEAST High osmolarity signaling protein ... | 201 | 0.3 | 37 | 25 | 42 | GO:0005935; C:cellular bud neck; IDA:SGD.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0043332; C:mating projection tip; IDA:SGD.::GO:0044459; C:plasma membrane part; IDA:SGD. | | | | | | | | | | GO:0005078; F:MAP-kinase scaffold activity; IMP:SGD.::GO:0005034; F:osmosensor activity; IPI:SGD. | | | | | | | | | | GO:0034605; P:cellular response to heat; IMP:SGD.::GO:0030010; P:establishment of cell polarity; IGI:SGD.::GO:0007231; P:osmosensory signaling pathway; IPI:SGD.::GO:0001402; P:signal transduction involved in filamentous growth; IMP:SGD. | 449 | Q8IZD9 | 2030 | DOCK3_HUMAN Dedicator of cytokinesis protein ... | 65 | 0.32 | 37.4 | 34 | 52 | GO:0005737; C:cytoplasm; IDA:HPA. | | | | | | | | | | GO:0005525; F:GTP binding; IEA:InterPro.::GO:0051020; F:GTPase binding; IEA:InterPro.::GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW.::GO:0017124; F:SH3 domain binding; IEA:UniProtKB-KW. | | | | | | | | | | | 450 | P08630 | 786 | BTKL_DROME Tyrosine-protein kinase Btk29A OS=... | 54 | 0.32 | 37.4 | 37 | 52 | GO:0005737; C:cytoplasm; IDA:FlyBase.::GO:0045172; C:germline ring canal; IDA:UniProtKB.::GO:0005886; C:plasma membrane; IDA:FlyBase. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC.::GO:0005543; F:phospholipid binding; IEA:InterPro. | | | | | | | | | | GO:0030036; P:actin cytoskeleton organization; IMP:FlyBase.::GO:0007349; P:cellularization; IMP:FlyBase.::GO:0007619; P:courtship behavior; NAS:FlyBase.::GO:0008340; P:determination of adult lifespan; IMP:UniProtKB.::GO:0042023; P:DNA endoreduplication; IMP:FlyBase.::GO:0007391; P:dorsal closure; TAS:FlyBase.::GO:0007301; P:female germline ring canal formation; IDA:UniProtKB.::GO:0008258; P:head involution; IMP:FlyBase.::GO:0007485; P:imaginal disc-derived male genitalia development; IMP:UniProtKB.::GO:0007254; P:JNK cascade; TAS:FlyBase.::GO:0030717; P:karyosome formation; IMP:FlyBase.::GO:0007424; P:open tracheal system development; IMP:FlyBase.::GO:0030723; P:ovarian fusome organization; IMP:FlyBase.::GO:0030833; P:regulation of actin filament polymerization; IMP:FlyBase.::GO:0007435; P:salivary gland morphogenesis; IMP:FlyBase.::GO:0046960; P:sensitization; IMP:FlyBase. | 451 | Q5TCZ1 | 1133 | SPD2A_HUMAN SH3 and PX domain-containing prot... | 52 | 3.2 | 34.3 | 29 | 56 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0042995; C:cell projection; IEA:UniProtKB-KW.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0002102; C:podosome; IDA:UniProtKB. | | | | | | | | | | GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:UniProtKB. | | | | | | | | | | GO:0007154; P:cell communication; IEA:InterPro.::GO:0006801; P:superoxide metabolic process; IDA:UniProtKB. |