rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
391 | Q4P3H6 | 1207 | SLA1_USTMA Actin cytoskeleton-regulatory comp... | 53 | 0.022 | 41.2 | 36 | 62 | GO:0030479; C:actin cortical patch; IEA:UniProtKB-SubCell.::GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0042802; F:identical protein binding; IEA:InterPro.::GO:0030674; F:protein binding, bridging; IEA:InterPro.::GO:0043130; F:ubiquitin binding; IEA:InterPro. | | | | | | | | | | GO:0006897; P:endocytosis; IEA:UniProtKB-KW. | 392 | Q02779 | 954 | M3K10_HUMAN Mitogen-activated protein kinase ... | 63 | 0.024 | 40.8 | 30 | 56 | GO:0005737; C:cytoplasm; IDA:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0043425; F:bHLH transcription factor binding; IPI:UniProtKB.::GO:0004706; F:JUN kinase kinase kinase activity; ISS:UniProtKB.::GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.::GO:0003714; F:transcription corepressor activity; ISS:UniProtKB. | | | | | | | | | | GO:0007257; P:activation of JUN kinase activity; ISS:UniProtKB.::GO:0006917; P:induction of apoptosis; TAS:ProtInc.::GO:0043433; P:negative regulation of sequence-specific DNA binding transcription factor activity; IMP:UniProtKB.::GO:0045892; P:negative regulation of transcription, DNA-dependent; IMP:UniProtKB.::GO:0018105; P:peptidyl-serine phosphorylation; IDA:UniProtKB.::GO:0018107; P:peptidyl-threonine phosphorylation; IDA:UniProtKB.::GO:0046330; P:positive regulation of JNK cascade; IMP:UniProtKB.::GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.::GO:0007224; P:smoothened signaling pathway; IMP:UniProtKB. | 393 | O14559 | 1287 | RHG33_HUMAN Rho GTPase-activating protein 33 ... | 69 | 0.028 | 40.8 | 23 | 52 | | | | | | | | | | | GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007165; P:signal transduction; IEA:InterPro. | 394 | Q6DCZ7 | 543 | FBP1L_XENLA Formin-binding protein 1-like OS=... | 55 | 0.028 | 40.4 | 36 | 62 | GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell.::GO:0016023; C:cytoplasmic membrane-bounded vesicle; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008289; F:lipid binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006897; P:endocytosis; IEA:UniProtKB-KW. | 395 | Q80YF9 | 1305 | RHG33_MOUSE Rho GTPase-activating protein 33 ... | 69 | 0.028 | 40.8 | 23 | 52 | GO:0005737; C:cytoplasm; IDA:MGI.::GO:0005886; C:plasma membrane; IDA:MGI. | | | | | | | | | | GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.::GO:0030675; F:Rac GTPase activator activity; IDA:MGI. | | | | | | | | | | GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007165; P:signal transduction; IEA:InterPro. | 396 | C5DQY5 | 371 | SHO1_ZYGRC High osmolarity signaling protein ... | 58 | 0.029 | 40.4 | 36 | 62 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006950; P:response to stress; IEA:UniProtKB-KW. | 397 | Q86WN1 | 690 | FCSD1_HUMAN FCH and double SH3 domains protei... | 86 | 0.03 | 40.4 | 31 | 49 | | | | | | | | | | | | | | | | | | | | | | 398 | A7E8B6 | 1150 | SLA1_SCLS1 Actin cytoskeleton-regulatory comp... | 53 | 1.1 | 35.8 | 30 | 55 | GO:0030479; C:actin cortical patch; IEA:UniProtKB-SubCell.::GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0042802; F:identical protein binding; IEA:InterPro.::GO:0030674; F:protein binding, bridging; IEA:InterPro.::GO:0043130; F:ubiquitin binding; IEA:InterPro. | | | | | | | | | | GO:0006897; P:endocytosis; IEA:UniProtKB-KW. | 399 | Q9P864 | 296 | SHO1_CYBJA High osmolarity signaling protein ... | 58 | 0.039 | 39.7 | 40 | 62 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006950; P:response to stress; IEA:UniProtKB-KW. | 400 | P55345 | 433 | ANM2_HUMAN Protein arginine N-methyltransfera... | 51 | 0.04 | 40 | 37 | 59 | GO:0005829; C:cytosol; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:UniProtKB. | | | | | | | | | | GO:0050681; F:androgen receptor binding; IPI:UniProtKB.::GO:0030331; F:estrogen receptor binding; IDA:UniProtKB.::GO:0008469; F:histone-arginine N-methyltransferase activity; ISS:UniProtKB.::GO:0008168; F:methyltransferase activity; IEA:InterPro.::GO:0042975; F:peroxisome proliferator activated receptor binding; IPI:UniProtKB.::GO:0033142; F:progesterone receptor binding; IPI:UniProtKB.::GO:0042803; F:protein homodimerization activity; IPI:UniProtKB.::GO:0042974; F:retinoic acid receptor binding; IPI:UniProtKB.::GO:0004871; F:signal transducer activity; TAS:ProtInc.::GO:0046966; F:thyroid hormone receptor binding; IPI:UniProtKB.::GO:0003713; F:transcription coactivator activity; IDA:UniProtKB. | | | | | | | | | | GO:0048588; P:developmental cell growth; ISS:UniProtKB.::GO:0006917; P:induction of apoptosis; IDA:UniProtKB.::GO:2000134; P:negative regulation of G1/S transition of mitotic cell cycle; ISS:UniProtKB.::GO:0032088; P:negative regulation of NF-kappaB transcription factor activity; IDA:UniProtKB.::GO:0045892; P:negative regulation of transcription, DNA-dependent; IDA:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; IDA:UniProtKB.::GO:0060765; P:regulation of androgen receptor signaling pathway; IDA:UniProtKB. | 401 | Q92266 | 380 | PEX13_PICPA Peroxisomal membrane protein PEX1... | 60 | 0.04 | 39.7 | 37 | 58 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005778; C:peroxisomal membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005515; F:protein binding; IPI:UniProtKB. | | | | | | | | | | GO:0016560; P:protein import into peroxisome matrix, docking; IEA:InterPro. | 402 | P16277 | 499 | BLK_MOUSE Tyrosine-protein kinase Blk OS=Mus ... | 54 | 0.041 | 40 | 37 | 57 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC. | | | | | | | | | | | 403 | P51451 | 505 | BLK_HUMAN Tyrosine-protein kinase Blk OS=Homo... | 54 | 0.041 | 40 | 37 | 56 | GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IDA:UniProtKB. | | | | | | | | | | GO:0050853; P:B cell receptor signaling pathway; IDA:UniProtKB.::GO:0007243; P:intracellular protein kinase cascade; TAS:ProtInc.::GO:0032024; P:positive regulation of insulin secretion; IMP:UniProtKB. | 404 | Q14185 | 1865 | DOCK1_HUMAN Dedicator of cytokinesis protein ... | 54 | 0.044 | 40 | 33 | 56 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005525; F:GTP binding; IEA:InterPro.::GO:0005096; F:GTPase activator activity; TAS:ProtInc.::GO:0051020; F:GTPase binding; IEA:InterPro.::GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW.::GO:0017124; F:SH3 domain binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006915; P:apoptotic process; TAS:ProtInc.::GO:0007411; P:axon guidance; TAS:Reactome.::GO:0007596; P:blood coagulation; TAS:Reactome.::GO:0007229; P:integrin-mediated signaling pathway; TAS:ProtInc.::GO:0006911; P:phagocytosis, engulfment; TAS:ProtInc.::GO:0007264; P:small GTPase mediated signal transduction; TAS:ProtInc. | 405 | Q8BUR4 | 1865 | DOCK1_MOUSE Dedicator of cytokinesis protein ... | 54 | 0.045 | 40 | 33 | 56 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005525; F:GTP binding; IEA:InterPro.::GO:0051020; F:GTPase binding; IEA:InterPro.::GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW.::GO:0017124; F:SH3 domain binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0016477; P:cell migration; IDA:MGI.::GO:0006909; P:phagocytosis; IEA:UniProtKB-KW. | 406 | P34092 | 1111 | MYOB_DICDI Myosin IB heavy chain OS=Dictyoste... | 62 | 0.047 | 40 | 35 | 60 | GO:0042641; C:actomyosin; IDA:dictyBase.::GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell.::GO:0031252; C:cell leading edge; TAS:dictyBase.::GO:0097203; C:phagocytic cup lip; IDA:dictyBase.::GO:0030670; C:phagocytic vesicle membrane; IDA:dictyBase.::GO:0031143; C:pseudopodium; IEA:UniProtKB-SubCell.::GO:0016461; C:unconventional myosin complex; IDA:dictyBase. | | | | | | | | | | GO:0051015; F:actin filament binding; IDA:dictyBase.::GO:0030898; F:actin-dependent ATPase activity; IDA:dictyBase.::GO:0005524; F:ATP binding; IDA:dictyBase.::GO:0000146; F:microfilament motor activity; IDA:dictyBase.::GO:0032031; F:myosin I head/neck binding; IDA:dictyBase. | | | | | | | | | | GO:0033275; P:actin-myosin filament sliding; IDA:dictyBase.::GO:0006935; P:chemotaxis; IEA:UniProtKB-KW.::GO:0006887; P:exocytosis; IEP:dictyBase.::GO:0006909; P:phagocytosis; IMP:dictyBase.::GO:0051707; P:response to other organism; TAS:dictyBase. | 407 | Q6TXD4 | 1580 | DNMBP_MOUSE Dynamin-binding protein OS=Mus mu... | 54 | 0.86 | 36.2 | 33 | 56 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005795; C:Golgi stack; IEA:UniProtKB-SubCell.::GO:0045202; C:synapse; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005515; F:protein binding; IPI:MGI.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro. | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro. | 408 | Q07840 | 426 | EM13_ECHMU Antigen EM13 OS=Echinococcus multi... | 46 | 0.055 | 39.7 | 37 | 61 | | | | | | | | | | | | | | | | | | | | | | 409 | Q6GUF4 | 550 | FBP1L_XENTR Formin-binding protein 1-like OS=... | 55 | 0.058 | 39.7 | 36 | 62 | GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell.::GO:0016023; C:cytoplasmic membrane-bounded vesicle; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008289; F:lipid binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006897; P:endocytosis; IEA:UniProtKB-KW. | 410 | P38479 | 617 | ABP1_SACEX Actin-binding protein OS=Saccharom... | 54 | 0.058 | 39.7 | 37 | 59 | GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW. | | | | | | | | | | | 411 | Q07839 | 416 | EG13_ECHGR Antigen EG13 OS=Echinococcus granu... | 46 | 0.058 | 39.3 | 37 | 61 | | | | | | | | | | | | | | | | | | | | | | 412 | B6QEE0 | 282 | SHO1_PENMQ High osmolarity signaling protein ... | 166 | 0.059 | 38.9 | 28 | 43 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006950; P:response to stress; IEA:UniProtKB-KW. | 413 | P14598 | 390 | NCF1_HUMAN Neutrophil cytosol factor 1 OS=Hom... | 78 | 0.062 | 39.3 | 29 | 51 | GO:0005829; C:cytosol; TAS:ProtInc.::GO:0043020; C:NADPH oxidase complex; TAS:BHF-UCL.::GO:0032010; C:phagolysosome; TAS:Reactome.::GO:0005625; C:soluble fraction; TAS:ProtInc. | | | | | | | | | | GO:0009055; F:electron carrier activity; TAS:UniProtKB.::GO:0005525; F:GTP binding; TAS:ProtInc.::GO:0003924; F:GTPase activity; TAS:ProtInc.::GO:0035091; F:phosphatidylinositol binding; IDA:UniProtKB.::GO:0017124; F:SH3 domain binding; IPI:BHF-UCL. | | | | | | | | | | GO:0002479; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; TAS:Reactome.::GO:0007154; P:cell communication; IEA:InterPro.::GO:0006968; P:cellular defense response; TAS:ProtInc.::GO:0045087; P:innate immune response; TAS:BHF-UCL.::GO:0006612; P:protein targeting to membrane; IDA:UniProtKB.::GO:0042554; P:superoxide anion generation; TAS:BHF-UCL. | 414 | A6NI72 | 391 | NCF1B_HUMAN Putative neutrophil cytosol facto... | 78 | 0.063 | 39.3 | 29 | 51 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0035091; F:phosphatidylinositol binding; IEA:InterPro. | | | | | | | | | | GO:0007154; P:cell communication; IEA:InterPro. | 415 | P41243 | 467 | MATK_RAT Megakaryocyte-associated tyrosine-pr... | 45 | 0.063 | 39.3 | 38 | 73 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC. | | | | | | | | | | | 416 | P97814 | 415 | PPIP1_MOUSE Proline-serine-threonine phosphat... | 58 | 0.098 | 38.5 | 28 | 53 | GO:0005826; C:actomyosin contractile ring; IDA:MGI.::GO:0032154; C:cleavage furrow; IDA:MGI.::GO:0030027; C:lamellipodium; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.::GO:0001725; C:stress fiber; IDA:MGI. | | | | | | | | | | GO:0003779; F:actin binding; IDA:MGI.::GO:0016491; F:oxidoreductase activity; IEA:InterPro.::GO:0019903; F:protein phosphatase binding; IDA:MGI. | | | | | | | | | | GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.::GO:0000910; P:cytokinesis; IC:MGI. | 417 | Q9UNA1 | 814 | RHG26_HUMAN Rho GTPase-activating protein 26 ... | 65 | 0.11 | 38.9 | 37 | 49 | GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008093; F:cytoskeletal adaptor activity; IEA:InterPro.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005100; F:Rho GTPase activator activity; NAS:UniProtKB.::GO:0017124; F:SH3 domain binding; IEA:InterPro. | | | | | | | | | | GO:0030036; P:actin cytoskeleton organization; NAS:UniProtKB.::GO:0046847; P:filopodium assembly; IEA:InterPro.::GO:0007399; P:nervous system development; NAS:UniProtKB.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome. | 418 | A7TKW4 | 1202 | SLA1_VANPO Actin cytoskeleton-regulatory comp... | 53 | 0.11 | 38.9 | 32 | 55 | GO:0030479; C:actin cortical patch; IEA:UniProtKB-SubCell.::GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0042802; F:identical protein binding; IEA:InterPro.::GO:0030674; F:protein binding, bridging; IEA:InterPro.::GO:0043130; F:ubiquitin binding; IEA:InterPro. | | | | | | | | | | GO:0006897; P:endocytosis; IEA:UniProtKB-KW. | 419 | P41242 | 505 | MATK_MOUSE Megakaryocyte-associated tyrosine-... | 45 | 0.11 | 38.5 | 38 | 71 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC. | | | | | | | | | | | 420 | C4QVD6 | 273 | SHO1_PICPG High osmolarity signaling protein ... | 123 | 0.11 | 38.1 | 28 | 43 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006950; P:response to stress; IEA:UniProtKB-KW. | 421 | A7TI28 | 358 | SHO1_VANPO High osmolarity signaling protein ... | 58 | 0.12 | 38.5 | 36 | 64 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006950; P:response to stress; IEA:UniProtKB-KW. |