Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YHR004C
Length:
446
Number of sequences:
5887
Description:
YHR004C NEM1 SGDID:S000001046, Chr VIII from 113094-111754, Genome Release 64-1-1, reverse complement, Verified ORF, "Probable catalytic subunit of Nem1p-Spo7p phosphatase holoenzyme; regulates nuclear growth by controlling phospholipid biosynthesis, required for normal nuclear envelope morphology and sporulation; homolog of the human protein Dullard"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
1P38757    446   NEM1_YEAST Nuclear envelope morphology protei...4460     911     100     100GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IDA:SGD.::GO:0005739; C:mitochondrion; IDA:SGD.::GO:0031965; C:nuclear membrane; IEA:UniProtKB-SubCell.
GO:0004721; F:phosphoprotein phosphatase activity; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0030437; P:ascospore formation; IMP:SGD.::GO:0071072; P:negative regulation of phospholipid biosynthetic process; IGI:SGD.::GO:0006998; P:nuclear envelope organization; IMP:SGD.
2O59718    476   NEM1_SCHPO Nuclear envelope morphology protei...1997e-50     181     50     67GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; NAS:PomBase.::GO:0031965; C:nuclear membrane; IEA:UniProtKB-SubCell.::GO:0008287; C:protein serine/threonine phosphatase complex; NAS:PomBase.
GO:0004721; F:phosphoprotein phosphatase activity; IEA:UniProtKB-KW.
GO:0030437; P:ascospore formation; ISS:PomBase.::GO:0033554; P:cellular response to stress; IEP:PomBase.::GO:0006998; P:nuclear envelope organization; ISS:PomBase.::GO:0046890; P:regulation of lipid biosynthetic process; ISS:PomBase.
3Q5U3T3    245   CNEPB_DANRE CTD nuclear envelope phosphatase ...1993e-43     157     44     62GO:0005789; C:endoplasmic reticulum membrane; ISS:UniProtKB.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0071595; C:Nem1-Spo7 phosphatase complex; ISS:UniProtKB.::GO:0031965; C:nuclear membrane; ISS:UniProtKB.
GO:0004722; F:protein serine/threonine phosphatase activity; ISS:UniProtKB.
GO:0006998; P:nuclear envelope organization; ISS:UniProtKB.::GO:0010867; P:positive regulation of triglyceride biosynthetic process; ISS:UniProtKB.::GO:0006470; P:protein dephosphorylation; ISS:UniProtKB.
4Q1RMV9    244   CNEP1_BOVIN CTD nuclear envelope phosphatase ...2053e-43     157     43     62GO:0005789; C:endoplasmic reticulum membrane; ISS:UniProtKB.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0071595; C:Nem1-Spo7 phosphatase complex; ISS:UniProtKB.::GO:0031965; C:nuclear membrane; ISS:UniProtKB.
GO:0004722; F:protein serine/threonine phosphatase activity; ISS:UniProtKB.
GO:0006998; P:nuclear envelope organization; ISS:UniProtKB.::GO:0010867; P:positive regulation of triglyceride biosynthetic process; ISS:UniProtKB.::GO:0006470; P:protein dephosphorylation; ISS:UniProtKB.::GO:0034504; P:protein localization to nucleus; ISS:UniProtKB.
5Q5U395    245   CNEPA_DANRE CTD nuclear envelope phosphatase ...2055e-43     157     43     62GO:0005789; C:endoplasmic reticulum membrane; ISS:UniProtKB.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0071595; C:Nem1-Spo7 phosphatase complex; ISS:UniProtKB.::GO:0031965; C:nuclear membrane; ISS:UniProtKB.
GO:0004722; F:protein serine/threonine phosphatase activity; ISS:UniProtKB.
GO:0006998; P:nuclear envelope organization; ISS:UniProtKB.::GO:0010867; P:positive regulation of triglyceride biosynthetic process; ISS:UniProtKB.::GO:0006470; P:protein dephosphorylation; ISS:UniProtKB.
6O95476    244   CNEP1_HUMAN CTD nuclear envelope phosphatase ...2056e-43     157     43     61GO:0005789; C:endoplasmic reticulum membrane; IDA:UniProtKB.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0071595; C:Nem1-Spo7 phosphatase complex; IDA:UniProtKB.::GO:0031965; C:nuclear membrane; IDA:UniProtKB.
GO:0005515; F:protein binding; IPI:IntAct.::GO:0004722; F:protein serine/threonine phosphatase activity; IMP:UniProtKB.
GO:0006998; P:nuclear envelope organization; IDA:UniProtKB.::GO:0010867; P:positive regulation of triglyceride biosynthetic process; IGI:UniProtKB.::GO:0006470; P:protein dephosphorylation; IDA:UniProtKB.::GO:0034504; P:protein localization to nucleus; IDA:UniProtKB.
7Q3B7T6    244   CNEP1_RAT CTD nuclear envelope phosphatase 1 ...2059e-43     156     43     61GO:0005789; C:endoplasmic reticulum membrane; ISS:UniProtKB.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0071595; C:Nem1-Spo7 phosphatase complex; ISS:UniProtKB.::GO:0031965; C:nuclear membrane; ISS:UniProtKB.
GO:0004722; F:protein serine/threonine phosphatase activity; ISS:UniProtKB.
GO:0006998; P:nuclear envelope organization; ISS:UniProtKB.::GO:0010867; P:positive regulation of triglyceride biosynthetic process; ISS:UniProtKB.::GO:0006470; P:protein dephosphorylation; ISS:UniProtKB.::GO:0034504; P:protein localization to nucleus; ISS:UniProtKB.
8Q3TP92    244   CNEP1_MOUSE CTD nuclear envelope phosphatase ...2059e-43     156     43     61GO:0005789; C:endoplasmic reticulum membrane; ISS:UniProtKB.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0071595; C:Nem1-Spo7 phosphatase complex; ISS:UniProtKB.::GO:0031965; C:nuclear membrane; ISS:UniProtKB.
GO:0004722; F:protein serine/threonine phosphatase activity; ISS:UniProtKB.
GO:0006998; P:nuclear envelope organization; ISS:UniProtKB.::GO:0010867; P:positive regulation of triglyceride biosynthetic process; ISS:UniProtKB.::GO:0006470; P:protein dephosphorylation; ISS:UniProtKB.::GO:0034504; P:protein localization to nucleus; ISS:UniProtKB.
9Q8JIL9    244   CNEP1_XENLA CTD nuclear envelope phosphatase ...1947e-42     154     44     62GO:0005789; C:endoplasmic reticulum membrane; ISS:UniProtKB.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0071595; C:Nem1-Spo7 phosphatase complex; ISS:UniProtKB.::GO:0031965; C:nuclear membrane; ISS:UniProtKB.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.
GO:0004722; F:protein serine/threonine phosphatase activity; ISS:UniProtKB.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0007399; P:nervous system development; IEA:UniProtKB-KW.::GO:0006998; P:nuclear envelope organization; ISS:UniProtKB.::GO:0010867; P:positive regulation of triglyceride biosynthetic process; ISS:UniProtKB.::GO:0006470; P:protein dephosphorylation; ISS:UniProtKB.
10Q28HW9    244   CNEP1_XENTR CTD nuclear envelope phosphatase ...1949e-42     154     44     62GO:0005789; C:endoplasmic reticulum membrane; ISS:UniProtKB.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0071595; C:Nem1-Spo7 phosphatase complex; ISS:UniProtKB.::GO:0031965; C:nuclear membrane; ISS:UniProtKB.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.
GO:0004722; F:protein serine/threonine phosphatase activity; ISS:UniProtKB.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0007399; P:nervous system development; IEA:UniProtKB-KW.::GO:0006998; P:nuclear envelope organization; ISS:UniProtKB.::GO:0010867; P:positive regulation of triglyceride biosynthetic process; ISS:UniProtKB.::GO:0006470; P:protein dephosphorylation; ISS:UniProtKB.
11Q9VRG7    243   CNEP1_DROME CTD nuclear envelope phosphatase ...2052e-39     147     41     60GO:0005789; C:endoplasmic reticulum membrane; ISS:UniProtKB.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0071595; C:Nem1-Spo7 phosphatase complex; ISS:UniProtKB.::GO:0031965; C:nuclear membrane; ISS:UniProtKB.
GO:0004722; F:protein serine/threonine phosphatase activity; ISS:UniProtKB.
GO:0007474; P:imaginal disc-derived wing vein specification; IMP:FlyBase.::GO:0030514; P:negative regulation of BMP signaling pathway; IMP:FlyBase.::GO:0006998; P:nuclear envelope organization; ISS:UniProtKB.::GO:0010867; P:positive regulation of triglyceride biosynthetic process; ISS:UniProtKB.::GO:0006470; P:protein dephosphorylation; ISS:UniProtKB.
12Q29I63    243   CNEP1_DROPS CTD nuclear envelope phosphatase ...2052e-39     147     41     60GO:0005789; C:endoplasmic reticulum membrane; ISS:UniProtKB.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0071595; C:Nem1-Spo7 phosphatase complex; ISS:UniProtKB.::GO:0031965; C:nuclear membrane; ISS:UniProtKB.
GO:0004722; F:protein serine/threonine phosphatase activity; ISS:UniProtKB.
GO:0006998; P:nuclear envelope organization; ISS:UniProtKB.::GO:0010867; P:positive regulation of triglyceride biosynthetic process; ISS:UniProtKB.::GO:0006470; P:protein dephosphorylation; ISS:UniProtKB.
13Q61C05    246   CNEP1_CAEBR CTD nuclear envelope phosphatase ...2044e-37     141     41     56GO:0005789; C:endoplasmic reticulum membrane; ISS:UniProtKB.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0071595; C:Nem1-Spo7 phosphatase complex; ISS:UniProtKB.::GO:0031965; C:nuclear membrane; ISS:UniProtKB.
GO:0004722; F:protein serine/threonine phosphatase activity; ISS:UniProtKB.
GO:0006998; P:nuclear envelope organization; ISS:UniProtKB.::GO:0010867; P:positive regulation of triglyceride biosynthetic process; ISS:UniProtKB.::GO:0006470; P:protein dephosphorylation; ISS:UniProtKB.
14Q20432    246   CNEP1_CAEEL CTD nuclear envelope phosphatase ...2041e-36     139     40     56GO:0005789; C:endoplasmic reticulum membrane; ISS:UniProtKB.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0071595; C:Nem1-Spo7 phosphatase complex; ISS:UniProtKB.::GO:0031965; C:nuclear membrane; ISS:UniProtKB.
GO:0004722; F:protein serine/threonine phosphatase activity; ISS:UniProtKB.
GO:0006998; P:nuclear envelope organization; ISS:UniProtKB.::GO:0010867; P:positive regulation of triglyceride biosynthetic process; ISS:UniProtKB.::GO:0006470; P:protein dephosphorylation; ISS:UniProtKB.::GO:0051783; P:regulation of nuclear division; IMP:WormBase.
15P58465    276   CTDSL_MOUSE CTD small phosphatase-like protei...1975e-32     127     37     58GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004721; F:phosphoprotein phosphatase activity; IEA:UniProtKB-KW.
16O15194    276   CTDSL_HUMAN CTD small phosphatase-like protei...1975e-32     127     37     58GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004721; F:phosphoprotein phosphatase activity; IEA:UniProtKB-KW.
17Q9PTJ6    275   CTDSL_CHICK CTD small phosphatase-like protei...1972e-31     125     37     58GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004721; F:phosphoprotein phosphatase activity; IEA:UniProtKB-KW.
18O14595    271   CTDS2_HUMAN Carboxy-terminal domain RNA polym...1967e-30     121     35     53GO:0005654; C:nucleoplasm; TAS:Reactome.::GO:0005625; C:soluble fraction; TAS:ProtInc.
GO:0008420; F:CTD phosphatase activity; IDA:UniProtKB.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0006987; P:activation of signaling protein activity involved in unfolded protein response; TAS:Reactome.::GO:0006470; P:protein dephosphorylation; IDA:UniProtKB.
19Q8BX07    270   CTDS2_MOUSE Carboxy-terminal domain RNA polym...1967e-30     121     35     55GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
20P58466    261   CTDS1_MOUSE Carboxy-terminal domain RNA polym...1952e-29     119     35     57GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0050768; P:negative regulation of neurogenesis; IDA:MGI.::GO:0045665; P:negative regulation of neuron differentiation; IDA:MGI.
21Q9GZU7    261   CTDS1_HUMAN Carboxy-terminal domain RNA polym...1952e-29     119     35     57GO:0005634; C:nucleus; IDA:UniProtKB.
GO:0008420; F:CTD phosphatase activity; IDA:UniProtKB.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0006470; P:protein dephosphorylation; IDA:UniProtKB.::GO:0006357; P:regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.
22Q54GB2    567   CTSL2_DICDI CTD small phosphatase-like protei...1957e-28     119     38     54
GO:0004721; F:phosphoprotein phosphatase activity; IEA:UniProtKB-KW.
23Q09695    325   YA22_SCHPO Uncharacterized protein C2F7.02c O...1985e-27     114     34     55GO:0005886; C:plasma membrane; ISS:PomBase.
GO:0004721; F:phosphoprotein phosphatase activity; ISS:PomBase.
GO:0033554; P:cellular response to stress; ISS:PomBase.::GO:0006470; P:protein dephosphorylation; IC:PomBase.::GO:0007165; P:signal transduction; NAS:PomBase.
24Q07800    427   PSR1_YEAST Phosphatase PSR1 OS=Saccharomyces ...2142e-25     110     34     54GO:0005886; C:plasma membrane; IDA:SGD.
GO:0004721; F:phosphoprotein phosphatase activity; IDA:SGD.::GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0009408; P:response to heat; IMP:UniProtKB.::GO:0009651; P:response to salt stress; IMP:UniProtKB.
25Q07949    397   PSR2_YEAST Probable phosphatase PSR2 OS=Sacch...1858e-25     108     35     57GO:0005886; C:plasma membrane; ISS:UniProtKB.
GO:0004721; F:phosphoprotein phosphatase activity; IEA:UniProtKB-KW.
GO:0009408; P:response to heat; IMP:UniProtKB.::GO:0009651; P:response to salt stress; IMP:UniProtKB.
26Q05D32    466   CTSL2_HUMAN CTD small phosphatase-like protei...1794e-21     99     35     51
GO:0004721; F:phosphoprotein phosphatase activity; IEA:UniProtKB-KW.
27Q9N4V4    287   SCPL3_CAEEL CTD small phosphatase-like protei...1864e-21     96.3     37     55
GO:0004721; F:phosphoprotein phosphatase activity; IEA:UniProtKB-KW.
28Q5XIK8    465   CTSL2_RAT CTD small phosphatase-like protein ...1795e-21     98.6     35     51
GO:0004721; F:phosphoprotein phosphatase activity; IEA:UniProtKB-KW.
29Q8BG15    465   CTSL2_MOUSE CTD small phosphatase-like protei...1795e-21     98.6     35     51
GO:0004721; F:phosphoprotein phosphatase activity; IEA:UniProtKB-KW.
30Q5F3Z7    466   CTSL2_CHICK CTD small phosphatase-like protei...1795e-21     98.6     35     51
GO:0004721; F:phosphoprotein phosphatase activity; IEA:UniProtKB-KW.
31A4QNX6    460   CTL2B_DANRE CTD small phosphatase-like protei...1792e-20     96.7     35     51
GO:0004721; F:phosphoprotein phosphatase activity; IEA:UniProtKB-KW.
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