Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YHL035C
Length:
1592
Number of sequences:
5887
Description:
YHL035C VMR1 SGDID:S000001027, Chr VIII from 32756-27978, Genome Release 64-1-1, reverse complement, Verified ORF, "Vacuolar membrane protein involved in multiple drug resistance and metal sensitivity; ATP-binding cassette (ABC) family member involved in drug transport; potential Cdc28p substrate; induced under respiratory conditions"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
301O35379    1528   MRP1_MOUSE Multidrug resistance-associated pr...2701e-16     90.1     27     47GO:0005887; C:integral to plasma membrane; IDA:MGI.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0042626; F:ATPase activity, coupled to transmembrane movement of substances; IEA:InterPro.
302O15438    1527   MRP3_HUMAN Canalicular multispecific organic ...5641e-16     90.5     22     42GO:0005887; C:integral to plasma membrane; TAS:ProtInc.::GO:0005624; C:membrane fraction; TAS:ProtInc.
GO:0005524; F:ATP binding; TAS:ProtInc.::GO:0042626; F:ATPase activity, coupled to transmembrane movement of substances; TAS:ProtInc.::GO:0008514; F:organic anion transmembrane transporter activity; TAS:ProtInc.
GO:0015721; P:bile acid and bile salt transport; TAS:Reactome.::GO:0008206; P:bile acid metabolic process; TAS:Reactome.
303Q04473    711   RTX3B_ACTPL Toxin RTX-III translocation ATP-b...3051e-16     89.7     28     47GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0030256; C:type I protein secretion system complex; IEA:InterPro.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0042626; F:ATPase activity, coupled to transmembrane movement of substances; IEA:InterPro.::GO:0008233; F:peptidase activity; IEA:InterPro.::GO:0008565; F:protein transporter activity; IEA:InterPro.
GO:0019835; P:cytolysis; IEA:UniProtKB-KW.::GO:0030253; P:protein secretion by the type I secretion system; IEA:InterPro.::GO:0006508; P:proteolysis; IEA:InterPro.
304Q1MAB5    587   NDVA_RHIL3 Beta-(1-->2)glucan export ATP-bind...3411e-16     89.4     26     44GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0015441; F:beta-glucan-transporting ATPase activity; IEA:EC.
305P36370    725   TAP1_RAT Antigen peptide transporter 1 OS=Rat...3971e-16     89.7     26     43GO:0005792; C:microsome; IDA:RGD.::GO:0005886; C:plasma membrane; IBA:RefGenome.::GO:0042825; C:TAP complex; IDA:RGD.
GO:0043531; F:ADP binding; IDA:RGD.::GO:0005524; F:ATP binding; IDA:UniProtKB.::GO:0042288; F:MHC class I protein binding; IDA:UniProtKB.::GO:0015421; F:oligopeptide-transporting ATPase activity; IBA:RefGenome.::GO:0015433; F:peptide antigen-transporting ATPase activity; TAS:RGD.::GO:0046982; F:protein heterodimerization activity; IDA:RGD.::GO:0042803; F:protein homodimerization activity; IPI:UniProtKB.::GO:0046978; F:TAP1 binding; IPI:UniProtKB.::GO:0046979; F:TAP2 binding; IPI:UniProtKB.::GO:0046980; F:tapasin binding; IPI:UniProtKB.
GO:0046968; P:peptide antigen transport; TAS:RGD.::GO:0001916; P:positive regulation of T cell mediated cytotoxicity; IBA:RefGenome.::GO:0042270; P:protection from natural killer cell mediated cytotoxicity; IMP:RGD.
306P23886    573   CYDC_ECOLI ATP-binding/permease protein CydC ...4531e-16     89     25     43GO:0016021; C:integral to membrane; IDA:EcoCyc.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0042626; F:ATPase activity, coupled to transmembrane movement of substances; IDA:EcoCyc.
GO:0033228; P:cysteine export; IDA:EcoCyc.::GO:0034775; P:glutathione transmembrane transport; IDA:EcoCyc.::GO:0070453; P:regulation of heme biosynthetic process; IMP:EcoCyc.
307Q8CG09    1532   MRP1_RAT Multidrug resistance-associated prot...5722e-16     89.7     23     42GO:0016323; C:basolateral plasma membrane; IDA:RGD.::GO:0005737; C:cytoplasm; IDA:RGD.::GO:0005887; C:integral to plasma membrane; IDA:RGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0015562; F:efflux transmembrane transporter activity; IDA:RGD.::GO:0015431; F:glutathione S-conjugate-exporting ATPase activity; IMP:RGD.::GO:0034634; F:glutathione transmembrane transporter activity; IMP:RGD.::GO:0034040; F:lipid-transporting ATPase activity; IDA:RGD.::GO:0005324; F:long-chain fatty acid transporter activity; IDA:RGD.::GO:0016491; F:oxidoreductase activity; IEA:InterPro.::GO:0046624; F:sphingolipid transporter activity; IMP:RGD.::GO:0008559; F:xenobiotic-transporting ATPase activity; IDA:RGD.
GO:0060326; P:cell chemotaxis; IMP:RGD.::GO:0043215; P:daunorubicin transport; IMP:RGD.::GO:0046618; P:drug export; IDA:RGD.::GO:0043526; P:neuroprotection; IMP:RGD.::GO:0033700; P:phospholipid efflux; IMP:RGD.::GO:0015911; P:plasma membrane long-chain fatty acid transport; IDA:RGD.::GO:0030335; P:positive regulation of cell migration; IMP:RGD.::GO:0006979; P:response to oxidative stress; IMP:RGD.
308Q5NIG3    609   MSBA_FRATT Lipid A export ATP-binding/permeas...2272e-16     88.2     32     52GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0042626; F:ATPase activity, coupled to transmembrane movement of substances; IEA:InterPro.
GO:0006869; P:lipid transport; IEA:UniProtKB-KW.
309Q14JW6    609   MSBA_FRAT1 Lipid A export ATP-binding/permeas...2272e-16     88.2     32     52GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0042626; F:ATPase activity, coupled to transmembrane movement of substances; IEA:InterPro.
GO:0006869; P:lipid transport; IEA:UniProtKB-KW.
310Q47908    593   MSBA_FRANO Lipid A export ATP-binding/permeas...2202e-16     88.6     32     52GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0042626; F:ATPase activity, coupled to transmembrane movement of substances; IEA:InterPro.
GO:0006869; P:lipid transport; IEA:UniProtKB-KW.
311Q28433    748   TAP1_GORGO Antigen peptide transporter 1 OS=G...3842e-16     89     25     44GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0042626; F:ATPase activity, coupled to transmembrane movement of substances; IEA:InterPro.::GO:0015197; F:peptide transporter activity; IEA:InterPro.
GO:0015031; P:protein transport; IEA:UniProtKB-KW.
312Q80WJ6    1366   MRP9_MOUSE Multidrug resistance-associated pr...2423e-16     89     25     49GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005739; C:mitochondrion; IDA:MGI.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0042626; F:ATPase activity, coupled to transmembrane movement of substances; IEA:InterPro.
313Q9M0M2    1236   AB9B_ARATH ABC transporter B family member 9 ...2363e-16     89     28     50GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0042626; F:ATPase activity, coupled to transmembrane movement of substances; IEA:InterPro.
314P33310    695   MDL1_YEAST ATP-dependent permease MDL1, mitoc...3793e-16     88.2     27     45GO:0016021; C:integral to membrane; IBA:RefGenome.::GO:0005743; C:mitochondrial inner membrane; IDA:SGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0015421; F:oligopeptide-transporting ATPase activity; IMP:SGD.
GO:0090374; P:oligopeptide export from mitochondrion; IMP:SGD.
315Q6UR05    1531   MRP1_CANFA Multidrug resistance-associated pr...2734e-16     88.6     26     48GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0042626; F:ATPase activity, coupled to transmembrane movement of substances; IEA:InterPro.
316Q9FHF1    1248   AB7B_ARATH ABC transporter B family member 7 ...4304e-16     88.2     22     43GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0042626; F:ATPase activity, coupled to transmembrane movement of substances; IEA:InterPro.
317P21958    724   TAP1_MOUSE Antigen peptide transporter 1 OS=M...3974e-16     87.8     25     43GO:0005739; C:mitochondrion; IDA:MGI.::GO:0005886; C:plasma membrane; IBA:RefGenome.::GO:0042825; C:TAP complex; IBA:RefGenome.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0042288; F:MHC class I protein binding; IPI:MGI.::GO:0015421; F:oligopeptide-transporting ATPase activity; IBA:RefGenome.::GO:0042605; F:peptide antigen binding; IBA:RefGenome.::GO:0046978; F:TAP1 binding; IBA:RefGenome.::GO:0046979; F:TAP2 binding; IBA:RefGenome.::GO:0046980; F:tapasin binding; IBA:RefGenome.
GO:0006952; P:defense response; IMP:MGI.::GO:0001916; P:positive regulation of T cell mediated cytotoxicity; IBA:RefGenome.
318Q03727    717   COMA_STRPN Transport/processing ATP-binding p...4454e-16     87.8     24     42GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0042626; F:ATPase activity, coupled to transmembrane movement of substances; IEA:InterPro.::GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.::GO:0019534; F:toxin transporter activity; IEA:InterPro.
GO:0030420; P:establishment of competence for transformation; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
319P21439    1286   MDR3_HUMAN Multidrug resistance protein 3 OS=...2875e-16     88.2     28     46GO:0016324; C:apical plasma membrane; IBA:RefGenome.::GO:0000139; C:Golgi membrane; IBA:RefGenome.::GO:0005887; C:integral to plasma membrane; TAS:ProtInc.::GO:0046581; C:intercellular canaliculus; IBA:RefGenome.::GO:0005624; C:membrane fraction; TAS:ProtInc.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008559; F:xenobiotic-transporting ATPase activity; IEA:EC.
GO:0044255; P:cellular lipid metabolic process; TAS:Reactome.
320P11599    707   HLYB_PROVU Alpha-hemolysin translocation ATP-...3087e-16     87     27     45GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0030256; C:type I protein secretion system complex; IEA:InterPro.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0042626; F:ATPase activity, coupled to transmembrane movement of substances; IEA:InterPro.::GO:0008233; F:peptidase activity; IEA:InterPro.::GO:0008565; F:protein transporter activity; IEA:InterPro.
GO:0019835; P:cytolysis; IEA:UniProtKB-KW.::GO:0044179; P:hemolysis in other organism; IEA:UniProtKB-KW.::GO:0030253; P:protein secretion by the type I secretion system; IEA:InterPro.::GO:0006508; P:proteolysis; IEA:InterPro.
321Q9ZR72    1286   AB1B_ARATH ABC transporter B family member 1 ...4408e-16     87.4     25     43GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IDA:TAIR.::GO:0009506; C:plasmodesma; IDA:TAIR.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0042626; F:ATPase activity, coupled to transmembrane movement of substances; IEA:InterPro.::GO:0010329; F:auxin efflux transmembrane transporter activity; IDA:TAIR.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0043481; P:anthocyanin accumulation in tissues in response to UV light; IMP:TAIR.::GO:0009926; P:auxin polar transport; IMP:TAIR.::GO:0009640; P:photomorphogenesis; IMP:TAIR.::GO:0009958; P:positive gravitropism; IGI:TAIR.::GO:0008361; P:regulation of cell size; IMP:TAIR.::GO:0009637; P:response to blue light; IMP:TAIR.::GO:0009624; P:response to nematode; IEP:TAIR.::GO:0048443; P:stamen development; IGI:TAIR.
322Q0BKJ3    609   MSBA_FRATO Lipid A export ATP-binding/permeas...2278e-16     86.7     32     51GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0042626; F:ATPase activity, coupled to transmembrane movement of substances; IEA:InterPro.
GO:0006869; P:lipid transport; IEA:UniProtKB-KW.
323Q2A1U9    609   MSBA_FRATH Lipid A export ATP-binding/permeas...2278e-16     86.7     32     51GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0042626; F:ATPase activity, coupled to transmembrane movement of substances; IEA:InterPro.
GO:0006869; P:lipid transport; IEA:UniProtKB-KW.
324Q4WLN7    727   ATM1_ASPFU Iron-sulfur clusters transporter a...4889e-16     86.7     22     44GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0042626; F:ATPase activity, coupled to transmembrane movement of substances; IEA:InterPro.
GO:0006811; P:ion transport; IEA:UniProtKB-KW.::GO:0055072; P:iron ion homeostasis; IEA:UniProtKB-KW.
325Q9M1Q9    1296   AB21B_ARATH ABC transporter B family member 2...2379e-16     87     28     49GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IDA:TAIR.::GO:0005774; C:vacuolar membrane; IDA:TAIR.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0042626; F:ATPase activity, coupled to transmembrane movement of substances; IEA:InterPro.
326P33527    1531   MRP1_HUMAN Multidrug resistance-associated pr...2680.000000000000001     87     25     46GO:0005794; C:Golgi apparatus; IDA:HPA.::GO:0005887; C:integral to plasma membrane; TAS:ProtInc.::GO:0005624; C:membrane fraction; TAS:ProtInc.::GO:0005634; C:nucleus; IDA:HPA.
GO:0005524; F:ATP binding; TAS:ProtInc.::GO:0042626; F:ATPase activity, coupled to transmembrane movement of substances; TAS:ProtInc.
GO:0019370; P:leukotriene biosynthetic process; TAS:Reactome.::GO:0006692; P:prostanoid metabolic process; TAS:Reactome.::GO:0042493; P:response to drug; TAS:ProtInc.
327P0AAG5    593   MDLB_ECOLI Multidrug resistance-like ATP-bind...3240.000000000000001     85.9     26     45GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008559; F:xenobiotic-transporting ATPase activity; IEA:EC.
328P0AAG6    593   MDLB_ECOL6 Multidrug resistance-like ATP-bind...3240.000000000000001     85.9     26     45GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008559; F:xenobiotic-transporting ATPase activity; IEA:EC.
329P0AAG7    593   MDLB_ECO57 Multidrug resistance-like ATP-bind...3240.000000000000001     85.9     26     45GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008559; F:xenobiotic-transporting ATPase activity; IEA:EC.
330P21448    1276   MDR1_CRIGR Multidrug resistance protein 1 OS=...4020.000000000000001     87     25     44GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008559; F:xenobiotic-transporting ATPase activity; IEA:EC.
331O14286    693   ATM1_SCHPO Iron-sulfur clusters transporter a...2910.000000000000001     86.3     25     47GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005743; C:mitochondrial inner membrane; IDA:PomBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0042626; F:ATPase activity, coupled to transmembrane movement of substances; IGI:PomBase.::GO:0005381; F:iron ion transmembrane transporter activity; TAS:PomBase.
GO:0006879; P:cellular iron ion homeostasis; IGI:PomBase.::GO:0034599; P:cellular response to oxidative stress; IMP:PomBase.
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