Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YHL027W
Length:
625
Number of sequences:
5887
Description:
YHL027W RIM101 SGDID:S000001019, Chr VIII from 51111-52988, Genome Release 64-1-1, Verified ORF, "Transcriptional repressor involved in response to pH and in cell wall construction; required for alkaline pH-stimulated haploid invasive growth and sporulation; activated by proteolytic processing; similar to A. nidulans PacC"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
91P79288    244   KLF9_PIG Krueppel-like factor 9 OS=Sus scrofa...890.0000002     56.2     33     43GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
92Q02447    781   SP3_HUMAN Transcription factor Sp3 OS=Homo sa...710.0005     47     34     51GO:0016605; C:PML body; IEA:UniProtKB-SubCell.
GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0045893; P:positive regulation of transcription, DNA-dependent; IDA:UniProtKB.
93P08047    785   SP1_HUMAN Transcription factor Sp1 OS=Homo sa...1040.0000002     58.2     29     39GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IC:UniProtKB.
GO:0043425; F:bHLH transcription factor binding; ISS:BHF-UCL.::GO:0003690; F:double-stranded DNA binding; IDA:BHF-UCL.::GO:0042826; F:histone deacetylase binding; IPI:BHF-UCL.::GO:0071837; F:HMG box domain binding; IPI:UniProtKB.::GO:0008022; F:protein C-terminus binding; IPI:UniProtKB.::GO:0042803; F:protein homodimerization activity; IDA:UniProtKB.::GO:0000978; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding; ISS:BHF-UCL.::GO:0001103; F:RNA polymerase II repressing transcription factor binding; ISS:BHF-UCL.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0043923; P:positive regulation by host of viral transcription; IDA:UniProtKB.
94O95600    359   KLF8_HUMAN Krueppel-like factor 8 OS=Homo sap...870.0000002     57     31     46GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
95Q60793    483   KLF4_MOUSE Krueppel-like factor 4 OS=Mus musc...880.0000002     57.4     32     43
GO:0001085; F:RNA polymerase II transcription factor binding; IPI:BHF-UCL.::GO:0043565; F:sequence-specific DNA binding; IDA:MGI.::GO:0001010; F:sequence-specific DNA binding transcription factor recruiting transcription factor activity; IDA:BHF-UCL.::GO:0044212; F:transcription regulatory region DNA binding; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0009913; P:epidermal cell differentiation; IMP:MGI.::GO:0048730; P:epidermis morphogenesis; IMP:MGI.::GO:0045444; P:fat cell differentiation; IMP:BHF-UCL.::GO:0045892; P:negative regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:BHF-UCL.::GO:0031077; P:post-embryonic camera-type eye development; IMP:MGI.::GO:0032526; P:response to retinoic acid; IDA:MGI.::GO:0019827; P:stem cell maintenance; IDA:UniProtKB.::GO:0006366; P:transcription from RNA polymerase II promoter; IDA:BHF-UCL.
96O35739    244   KLF9_MOUSE Krueppel-like factor 9 OS=Mus musc...2430.0000002     55.8     25     37GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
97Q5IS56    1580   GLI3_PANTR Transcriptional activator GLI3 OS=...1420.0005     47     23     37GO:0005929; C:cilium; IEA:UniProtKB-SubCell.::GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0045893; P:positive regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
98P10071    1580   GLI3_HUMAN Transcriptional activator GLI3 OS=...1420.0006     47     23     37GO:0005929; C:cilium; IDA:UniProtKB.::GO:0005829; C:cytosol; IDA:UniProtKB.::GO:0005730; C:nucleolus; IDA:HPA.
GO:0008013; F:beta-catenin binding; IPI:UniProtKB.::GO:0035035; F:histone acetyltransferase binding; IPI:UniProtKB.::GO:0042826; F:histone deacetylase binding; IDA:UniProtKB.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0042733; P:embryonic digit morphogenesis; TAS:BHF-UCL.::GO:0046639; P:negative regulation of alpha-beta T cell differentiation; ISS:BHF-UCL.::GO:0090090; P:negative regulation of canonical Wnt receptor signaling pathway; IDA:UniProtKB.::GO:0045879; P:negative regulation of smoothened signaling pathway; ISS:BHF-UCL.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.::GO:0045060; P:negative thymic T cell selection; ISS:BHF-UCL.::GO:0043585; P:nose morphogenesis; TAS:BHF-UCL.::GO:0046638; P:positive regulation of alpha-beta T cell differentiation; ISS:BHF-UCL.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.::GO:0070242; P:thymocyte apoptotic process; ISS:BHF-UCL.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
99P10070    1586   GLI2_HUMAN Zinc finger protein GLI2 OS=Homo s...940.002     45.4     29     41GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0043565; F:sequence-specific DNA binding; IDA:UniProtKB.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IDA:UniProtKB.
GO:0007411; P:axon guidance; ISS:UniProtKB.::GO:0048754; P:branching morphogenesis of a tube; ISS:UniProtKB.::GO:0008283; P:cell proliferation; IDA:UniProtKB.::GO:0021696; P:cerebellar cortex morphogenesis; ISS:UniProtKB.::GO:0048589; P:developmental growth; ISS:UniProtKB.::GO:0048566; P:embryonic digestive tract development; ISS:UniProtKB.::GO:0009913; P:epidermal cell differentiation; IDA:UniProtKB.::GO:0021508; P:floor plate formation; ISS:UniProtKB.::GO:0007507; P:heart development; ISS:UniProtKB.::GO:0007442; P:hindgut morphogenesis; ISS:UniProtKB.::GO:0001822; P:kidney development; ISS:UniProtKB.::GO:0030324; P:lung development; ISS:UniProtKB.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IMP:UniProtKB.::GO:0042475; P:odontogenesis of dentin-containing tooth; ISS:UniProtKB.::GO:0002076; P:osteoblast development; ISS:UniProtKB.::GO:0001649; P:osteoblast differentiation; IDA:UniProtKB.::GO:0021983; P:pituitary gland development; ISS:UniProtKB.::GO:0045740; P:positive regulation of DNA replication; IDA:UniProtKB.::GO:0033089; P:positive regulation of T cell differentiation in thymus; ISS:BHF-UCL.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.::GO:0009954; P:proximal/distal pattern formation; ISS:UniProtKB.::GO:0001501; P:skeletal system development; ISS:UniProtKB.::GO:0021775; P:smoothened signaling pathway involved in ventral spinal cord interneuron specification; ISS:UniProtKB.::GO:0021965; P:spinal cord ventral commissure morphogenesis; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
100Q8VDL9    521   GLIS2_MOUSE Zinc finger protein GLIS2 OS=Mus ...1210.73     36.6     24     36GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016607; C:nuclear speck; IDA:UniProtKB.
GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0001077; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; IDA:BHF-UCL.::GO:0044212; F:transcription regulatory region DNA binding; IDA:BHF-UCL.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0043433; P:negative regulation of sequence-specific DNA binding transcription factor activity; IDA:BHF-UCL.::GO:0045879; P:negative regulation of smoothened signaling pathway; IMP:UniProtKB.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:BHF-UCL.::GO:0007399; P:nervous system development; IEA:UniProtKB-KW.
101Q9Y5W3    355   KLF2_HUMAN Krueppel-like factor 2 OS=Homo sap...880.0000003     56.2     32     45GO:0005634; C:nucleus; NAS:UniProtKB.
GO:0003700; F:sequence-specific DNA binding transcription factor activity; NAS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0051247; P:positive regulation of protein metabolic process; IGI:BHF-UCL.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IGI:BHF-UCL.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
102Q0VA40    422   SP9_XENTR Transcription factor Sp9 OS=Xenopus...540.0005     46.6     37     56GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
103O14901    512   KLF11_HUMAN Krueppel-like factor 11 OS=Homo s...1300.0000003     56.6     27     44GO:0005634; C:nucleus; TAS:ProtInc.
GO:0000981; F:sequence-specific DNA binding RNA polymerase II transcription factor activity; IDA:BHF-UCL.::GO:0044212; F:transcription regulatory region DNA binding; IDA:BHF-UCL.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0008285; P:negative regulation of cell proliferation; IDA:BHF-UCL.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:BHF-UCL.::GO:0043065; P:positive regulation of apoptotic process; IDA:BHF-UCL.::GO:0000115; P:regulation of transcription involved in S phase of mitotic cell cycle; IDA:BHF-UCL.
104Q8BLM0    355   KLF8_MOUSE Krueppel-like factor 8 OS=Mus musc...870.0000004     56.2     31     46GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
105P47043    880   ZAP1_YEAST Zinc-responsive transcriptional re...860.035     40.8     33     41GO:0005634; C:nucleus; IDA:SGD.
GO:0000977; F:RNA polymerase II regulatory region sequence-specific DNA binding; IDA:SGD.::GO:0000981; F:sequence-specific DNA binding RNA polymerase II transcription factor activity; IDA:SGD.::GO:0008270; F:zinc ion binding; IDA:SGD.
GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:SGD.::GO:0034225; P:regulation of transcription from RNA polymerase II promoter in response to zinc ion starvation; IMP:SGD.
106Q6NW96    439   SP9_DANRE Transcription factor Sp9 OS=Danio r...540.0008     45.8     37     56GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0035118; P:embryonic pectoral fin morphogenesis; IMP:ZFIN.::GO:0045743; P:positive regulation of fibroblast growth factor receptor signaling pathway; IMP:ZFIN.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
107O43474    513   KLF4_HUMAN Krueppel-like factor 4 OS=Homo sap...880.0000004     56.6     32     43GO:0000790; C:nuclear chromatin; IDA:BHF-UCL.
GO:0000987; F:core promoter proximal region sequence-specific DNA binding; IDA:BHF-UCL.::GO:0001077; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; IMP:BHF-UCL.::GO:0001085; F:RNA polymerase II transcription factor binding; IPI:BHF-UCL.::GO:0001190; F:RNA polymerase II transcription factor binding transcription factor activity involved in positive regulation of transcription; IDA:BHF-UCL.::GO:0001010; F:sequence-specific DNA binding transcription factor recruiting transcription factor activity; ISS:BHF-UCL.::GO:0008270; F:zinc ion binding; NAS:UniProtKB.
GO:0071363; P:cellular response to growth factor stimulus; IDA:BHF-UCL.::GO:0045444; P:fat cell differentiation; ISS:BHF-UCL.::GO:0007500; P:mesodermal cell fate determination; TAS:ProtInc.::GO:0090051; P:negative regulation of cell migration involved in sprouting angiogenesis; IDA:BHF-UCL.::GO:0008285; P:negative regulation of cell proliferation; TAS:ProtInc.::GO:2000342; P:negative regulation of chemokine (C-X-C motif) ligand 2 production; IDA:BHF-UCL.::GO:0043154; P:negative regulation of cysteine-type endopeptidase activity involved in apoptotic process; IDA:BHF-UCL.::GO:0034115; P:negative regulation of heterotypic cell-cell adhesion; IDA:BHF-UCL.::GO:0050728; P:negative regulation of inflammatory response; TAS:BHF-UCL.::GO:0045415; P:negative regulation of interleukin-8 biosynthetic process; IDA:BHF-UCL.::GO:0032088; P:negative regulation of NF-kappaB transcription factor activity; IDA:BHF-UCL.::GO:0060761; P:negative regulation of response to cytokine stimulus; IDA:BHF-UCL.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:BHF-UCL.::GO:0046985; P:positive regulation of hemoglobin biosynthetic process; IMP:BHF-UCL.::GO:0035166; P:post-embryonic hemopoiesis; IMP:BHF-UCL.::GO:0019827; P:stem cell maintenance; ISS:UniProtKB.
108P55879    663   GLI2_CHICK Zinc finger protein GLI2 OS=Gallus...940.003     44.7     29     43GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0045893; P:positive regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
109P46099    358   KLF1_MOUSE Krueppel-like factor 1 OS=Mus musc...880.0000006     55.8     32     44GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0033613; F:activating transcription factor binding; IPI:BHF-UCL.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0019904; F:protein domain specific binding; IPI:BHF-UCL.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:BHF-UCL.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
110Q91661    1361   GLI4_XENLA Zinc finger protein GLI4 OS=Xenopu...624.3     34.3     29     45GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
111Q0VGT2    1544   GLI2_MOUSE Zinc finger protein GLI2 OS=Mus mu...940.002     45.1     29     41GO:0005737; C:cytoplasm; IDA:MGI.::GO:0005624; C:membrane fraction; IDA:MGI.::GO:0031512; C:motile primary cilium; IDA:MGI.::GO:0005634; C:nucleus; IDA:UniProtKB.
GO:0003682; F:chromatin binding; IDA:MGI.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0043565; F:sequence-specific DNA binding; IDA:MGI.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:MGI.::GO:0044212; F:transcription regulatory region DNA binding; IDA:MGI.
GO:0006915; P:apoptotic process; IGI:MGI.::GO:0007411; P:axon guidance; IMP:MGI.::GO:0048754; P:branching morphogenesis of a tube; IMP:MGI.::GO:0008283; P:cell proliferation; IGI:MGI.::GO:0071407; P:cellular response to organic cyclic compound; IDA:MGI.::GO:0021696; P:cerebellar cortex morphogenesis; IMP:MGI.::GO:0090103; P:cochlea morphogenesis; IMP:MGI.::GO:0048589; P:developmental growth; IMP:MGI.::GO:0048566; P:embryonic digestive tract development; IMP:MGI.::GO:0042733; P:embryonic digit morphogenesis; IMP:MGI.::GO:0021508; P:floor plate formation; IMP:MGI.::GO:0060322; P:head development; IMP:MGI.::GO:0007507; P:heart development; IGI:MGI.::GO:0007442; P:hindgut morphogenesis; IMP:MGI.::GO:0001701; P:in utero embryonic development; IMP:MGI.::GO:0001822; P:kidney development; IGI:MGI.::GO:0030324; P:lung development; IMP:MGI.::GO:0060603; P:mammary gland duct morphogenesis; IMP:MGI.::GO:0032331; P:negative regulation of chondrocyte differentiation; IMP:MGI.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IGI:MGI.::GO:0060032; P:notochord regression; IGI:MGI.::GO:0042475; P:odontogenesis of dentin-containing tooth; IMP:MGI.::GO:0002076; P:osteoblast development; IDA:MGI.::GO:0021983; P:pituitary gland development; IGI:MGI.::GO:0045666; P:positive regulation of neuron differentiation; IGI:MGI.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:MGI.::GO:0060513; P:prostatic bud formation; IMP:MGI.::GO:0008589; P:regulation of smoothened signaling pathway; IMP:MGI.::GO:0001501; P:skeletal system development; IMP:MGI.::GO:0060831; P:smoothened signaling pathway involved in dorsal/ventral neural tube patterning; IGI:MGI.::GO:0021938; P:smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation; IMP:MGI.::GO:0021776; P:smoothened signaling pathway involved in spinal cord motor neuron cell fate specification; IGI:MGI.::GO:0021775; P:smoothened signaling pathway involved in ventral spinal cord interneuron specification; IGI:MGI.::GO:0021965; P:spinal cord ventral commissure morphogenesis; IMP:MGI.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
112O70494    783   SP3_MOUSE Transcription factor Sp3 OS=Mus mus...710.0006     46.6     34     51GO:0016605; C:PML body; IEA:UniProtKB-SubCell.::GO:0017053; C:transcriptional repressor complex; IDA:UniProtKB.
GO:0003682; F:chromatin binding; IDA:MGI.::GO:0000987; F:core promoter proximal region sequence-specific DNA binding; IDA:MGI.::GO:0003690; F:double-stranded DNA binding; IDA:MGI.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0001078; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription; IDA:UniProtKB.::GO:0000979; F:RNA polymerase II core promoter sequence-specific DNA binding; IDA:MGI.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0030183; P:B cell differentiation; IMP:MGI.::GO:0060216; P:definitive hemopoiesis; IGI:MGI.::GO:0048596; P:embryonic camera-type eye morphogenesis; IGI:MGI.::GO:0001892; P:embryonic placenta development; IGI:MGI.::GO:0060136; P:embryonic process involved in female pregnancy; IGI:MGI.::GO:0048706; P:embryonic skeletal system development; IGI:MGI.::GO:0043353; P:enucleate erythrocyte differentiation; IGI:MGI.::GO:0030851; P:granulocyte differentiation; IMP:MGI.::GO:0001889; P:liver development; IGI:MGI.::GO:0030324; P:lung development; IGI:MGI.::GO:0030219; P:megakaryocyte differentiation; IGI:MGI.::GO:0030224; P:monocyte differentiation; IMP:MGI.::GO:0001779; P:natural killer cell differentiation; IMP:MGI.::GO:0001503; P:ossification; IGI:MGI.::GO:0030217; P:T cell differentiation; IMP:MGI.::GO:0001829; P:trophectodermal cell differentiation; IGI:MGI.
113Q61602    1583   GLI3_MOUSE Transcriptional activator GLI3 OS=...940.0006     47     30     43GO:0005929; C:cilium; IEA:UniProtKB-SubCell.::GO:0017053; C:transcriptional repressor complex; IDA:MGI.
GO:0003682; F:chromatin binding; IGI:MGI.::GO:0043565; F:sequence-specific DNA binding; IDA:MGI.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0060873; P:anterior semicircular canal development; IMP:MGI.::GO:0009952; P:anterior/posterior pattern specification; IMP:MGI.::GO:0060840; P:artery development; IGI:MGI.::GO:0007411; P:axon guidance; IMP:MGI.::GO:0001658; P:branching involved in ureteric bud morphogenesis; IGI:MGI.::GO:0048593; P:camera-type eye morphogenesis; IMP:MGI.::GO:0061005; P:cell differentiation involved in kidney development; IGI:MGI.::GO:0021801; P:cerebral cortex radial glia guided migration; IMP:MGI.::GO:0048589; P:developmental growth; IMP:MGI.::GO:0048557; P:embryonic digestive tract morphogenesis; IMP:MGI.::GO:0042733; P:embryonic digit morphogenesis; IMP:MGI.::GO:0048704; P:embryonic skeletal system morphogenesis; IGI:MGI.::GO:0021798; P:forebrain dorsal/ventral pattern formation; IMP:MGI.::GO:0021861; P:forebrain radial glial cell differentiation; IMP:MGI.::GO:0060364; P:frontal suture morphogenesis; IMP:MGI.::GO:0007507; P:heart development; IGI:MGI.::GO:0007442; P:hindgut morphogenesis; IGI:MGI.::GO:0001701; P:in utero embryonic development; IMP:MGI.::GO:0060366; P:lambdoid suture morphogenesis; IMP:MGI.::GO:0022018; P:lateral ganglionic eminence cell proliferation; IMP:MGI.::GO:0060875; P:lateral semicircular canal development; IMP:MGI.::GO:0030324; P:lung development; IMP:MGI.::GO:0060594; P:mammary gland specification; IGI:MGI.::GO:0030318; P:melanocyte differentiation; IMP:MGI.::GO:0001656; P:metanephros development; IGI:MGI.::GO:0046639; P:negative regulation of alpha-beta T cell differentiation; IMP:BHF-UCL.::GO:0043066; P:negative regulation of apoptotic process; IMP:MGI.::GO:0008285; P:negative regulation of cell proliferation; IMP:MGI.::GO:0045665; P:negative regulation of neuron differentiation; IMP:MGI.::GO:0045879; P:negative regulation of smoothened signaling pathway; IMP:BHF-UCL.::GO:0045060; P:negative thymic T cell selection; IMP:BHF-UCL.::GO:0042475; P:odontogenesis of dentin-containing tooth; IGI:MGI.::GO:0048709; P:oligodendrocyte differentiation; IGI:MGI.::GO:0021631; P:optic nerve morphogenesis; IMP:MGI.::GO:0060021; P:palate development; IMP:MGI.::GO:0046638; P:positive regulation of alpha-beta T cell differentiation; IMP:BHF-UCL.::GO:0032332; P:positive regulation of chondrocyte differentiation; IMP:MGI.::GO:0002052; P:positive regulation of neuroblast proliferation; IMP:MGI.::GO:0045669; P:positive regulation of osteoblast differentiation; IMP:MGI.::GO:0042307; P:positive regulation of protein import into nucleus; IGI:MGI.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:BHF-UCL.::GO:0016485; P:protein processing; IDA:MGI.::GO:0009954; P:proximal/distal pattern formation; IMP:MGI.::GO:0060367; P:sagittal suture morphogenesis; IMP:MGI.::GO:0060831; P:smoothened signaling pathway involved in dorsal/ventral neural tube patterning; IGI:MGI.::GO:0021776; P:smoothened signaling pathway involved in spinal cord motor neuron cell fate specification; IGI:MGI.::GO:0021775; P:smoothened signaling pathway involved in ventral spinal cord interneuron specification; IGI:MGI.::GO:0070242; P:thymocyte apoptotic process; IMP:BHF-UCL.::GO:0043586; P:tongue development; IMP:MGI.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
114Q6P0J3    437   SP8_DANRE Transcription factor Sp8 OS=Danio r...870.0000008     55.5     32     45GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0030326; P:embryonic limb morphogenesis; IMP:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
115Q8BMJ8    486   SP8_MOUSE Transcription factor Sp8 OS=Mus mus...540.0007     46.2     37     56GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0009953; P:dorsal/ventral pattern formation; IMP:MGI.::GO:0030326; P:embryonic limb morphogenesis; IMP:UniProtKB.::GO:0009954; P:proximal/distal pattern formation; IMP:MGI.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
116Q64HY5    480   SP8_CHICK Transcription factor Sp8 OS=Gallus ...540.0007     46.2     37     56GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0030326; P:embryonic limb morphogenesis; IMP:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
117Q8K1M4    789   GLIS1_MOUSE Zinc finger protein GLIS1 OS=Mus ...890.003     44.7     30     43GO:0005634; C:nucleus; IDA:MGI.
GO:0003677; F:DNA binding; IDA:MGI.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:MGI.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
118Q8IXZ3    490   SP8_HUMAN Transcription factor Sp8 OS=Homo sa...540.0007     46.2     37     56GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
119O89091    479   KLF10_MOUSE Krueppel-like factor 10 OS=Mus mu...1020.000001     55.5     28     41GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0030282; P:bone mineralization; IMP:MGI.::GO:0045672; P:positive regulation of osteoclast differentiation; IMP:MGI.::GO:0006355; P:regulation of transcription, DNA-dependent; IMP:MGI.::GO:0035019; P:somatic stem cell maintenance; IDA:MGI.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
120Q8CFA7    341   KLF17_MOUSE Krueppel-like factor 17 OS=Mus mu...880.000001     54.7     30     47GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:UniProtKB.::GO:0044212; F:transcription regulatory region DNA binding; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007276; P:gamete generation; IDA:MGI.::GO:0006357; P:regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
121Q8NBF1    620   GLIS1_HUMAN Zinc finger protein GLIS1 OS=Homo...890.004     43.9     30     43GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0006366; P:transcription from RNA polymerase II promoter; ISS:UniProtKB.
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