Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YHL022C
Length:
398
Number of sequences:
5887
Description:
YHL022C SPO11 SGDID:S000001014, Chr VIII from 64157-62961, Genome Release 64-1-1, reverse complement, Verified ORF, "Meiosis-specific protein that initiates meiotic recombination by catalyzing the formation of double-strand breaks in DNA via a transesterification reaction; required for homologous chromosome pairing and synaptonemal complex formation"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
1P23179    398   SPO11_YEAST Meiosis-specific protein SPO11 OS...3980     825     100     100GO:0000228; C:nuclear chromosome; IPI:SGD.::GO:0005654; C:nucleoplasm; TAS:Reactome.
GO:0005524; F:ATP binding; IEA:InterPro.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0016889; F:endodeoxyribonuclease activity, producing 3'-phosphomonoesters; IMP:SGD.
GO:0006259; P:DNA metabolic process; IEA:InterPro.::GO:0042138; P:meiotic DNA double-strand break formation; IMP:SGD.::GO:0030435; P:sporulation resulting in formation of a cellular spore; IEA:UniProtKB-KW.
2P40384    345   REC12_SCHPO Meiotic recombination protein rec...2867e-18     87.4     30     47GO:0005829; C:cytosol; IDA:PomBase.::GO:0000228; C:nuclear chromosome; ISS:PomBase.
GO:0005524; F:ATP binding; IEA:InterPro.::GO:0003677; F:DNA binding; IEA:InterPro.::GO:0016889; F:endodeoxyribonuclease activity, producing 3'-phosphomonoesters; ISS:PomBase.
GO:0045143; P:homologous chromosome segregation; IMP:PomBase.::GO:0042138; P:meiotic DNA double-strand break formation; IMP:PomBase.::GO:0045144; P:meiotic sister chromatid segregation; IMP:PomBase.::GO:0007131; P:reciprocal meiotic recombination; IMP:PomBase.
3Q9M4A2    362   SPO11_ARATH Meiotic recombination protein SPO...2400.00000000000002     77.8     28     46GO:0005694; C:chromosome; IEA:InterPro.::GO:0005634; C:nucleus; IDA:TAIR.
GO:0005524; F:ATP binding; IEA:InterPro.::GO:0003677; F:DNA binding; IDA:TAIR.::GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
GO:0051026; P:chiasma assembly; IMP:TAIR.::GO:0034090; P:maintenance of meiotic sister chromatid cohesion; IGI:TAIR.::GO:0042138; P:meiotic DNA double-strand break formation; IGI:TAIR.::GO:0000706; P:meiotic DNA double-strand break processing; IGI:TAIR.::GO:0007131; P:reciprocal meiotic recombination; IMP:TAIR.
4Q9WTK8    396   SPO11_MOUSE Meiotic recombination protein SPO...2030.0000000000004     73.9     31     50GO:0000781; C:chromosome, telomeric region; IDA:MGI.::GO:0005654; C:nucleoplasm; TAS:Reactome.
GO:0005524; F:ATP binding; IEA:InterPro.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
GO:0007141; P:male meiosis I; IMP:MGI.::GO:0001541; P:ovarian follicle development; IMP:MGI.::GO:0034502; P:protein localization to chromosome; IMP:MGI.::GO:0007131; P:reciprocal meiotic recombination; IMP:MGI.::GO:0007286; P:spermatid development; IMP:MGI.::GO:0000238; P:zygotene; IMP:MGI.
5Q9LZ03    427   TOP6A_ARATH DNA topoisomerase 6 subunit A OS=...1830.000000000007     70.1     30     49GO:0005694; C:chromosome; IEA:InterPro.::GO:0005634; C:nucleus; IDA:TAIR.
GO:0005524; F:ATP binding; IEA:InterPro.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; TAS:TAIR.::GO:0042802; F:identical protein binding; IPI:TAIR.
GO:0006265; P:DNA topological change; IEA:InterPro.::GO:0009957; P:epidermal cell fate specification; IMP:TAIR.
6Q9Y5K1    396   SPO11_HUMAN Meiotic recombination protein SPO...3450.0000000001     65.9     25     44GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:InterPro.::GO:0003677; F:DNA binding; TAS:ProtInc.::GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
GO:0007292; P:female gamete generation; TAS:ProtInc.::GO:0007131; P:reciprocal meiotic recombination; TAS:ProtInc.
7Q22236    425   SPO11_CAEEL Meiotic recombination protein spo...2670.000001     53.9     25     46GO:0005694; C:chromosome; IEA:InterPro.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:InterPro.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
GO:0006259; P:DNA metabolic process; IEA:InterPro.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0040007; P:growth; IMP:WormBase.::GO:0007126; P:meiosis; IMP:WormBase.::GO:0002119; P:nematode larval development; IMP:WormBase.::GO:0030435; P:sporulation resulting in formation of a cellular spore; IEA:UniProtKB-KW.
8Q8SVS9    303   SPO11_ENCCU Probable meiosis-specific protein...2090.000002     53.1     25     43GO:0005694; C:chromosome; IEA:InterPro.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:InterPro.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
GO:0006259; P:DNA metabolic process; IEA:InterPro.::GO:0007126; P:meiosis; IEA:UniProtKB-KW.::GO:0030435; P:sporulation resulting in formation of a cellular spore; IEA:UniProtKB-KW.
9Q9YE67    389   TOP6A_AERPE Type II DNA topoisomerase VI subu...1580.000002     53.1     28     43GO:0005694; C:chromosome; IEA:InterPro.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0006265; P:DNA topological change; IEA:InterPro.
10Q971T1    387   TOP6A_SULTO Type II DNA topoisomerase VI subu...1090.00001     50.4     30     52GO:0005694; C:chromosome; IEA:InterPro.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0006265; P:DNA topological change; IEA:InterPro.
11A2BLE8    387   TOP6A_HYPBU Type 2 DNA topoisomerase 6 subuni...2620.00002     50.1     26     42GO:0005694; C:chromosome; IEA:InterPro.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0006265; P:DNA topological change; IEA:InterPro.
12O05208    389   TOP6A_SULSH Type II DNA topoisomerase VI subu...1270.00007     48.1     30     47GO:0005694; C:chromosome; IEA:InterPro.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0006265; P:DNA topological change; IEA:InterPro.
13Q468I6    369   TOP6A_METBF Type 2 DNA topoisomerase 6 subuni...1990.0002     47     23     45GO:0005694; C:chromosome; IEA:InterPro.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0006265; P:DNA topological change; IEA:InterPro.
14Q9M4A1    383   SPO12_ARATH Meiotic recombination protein SPO...1320.0002     46.6     29     48GO:0005694; C:chromosome; IEA:InterPro.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:InterPro.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
GO:0051026; P:chiasma assembly; IMP:TAIR.::GO:0006259; P:DNA metabolic process; IEA:InterPro.::GO:0009553; P:embryo sac development; IMP:TAIR.::GO:0042138; P:meiotic DNA double-strand break formation; IGI:TAIR.::GO:0009555; P:pollen development; IMP:TAIR.::GO:0048316; P:seed development; IMP:TAIR.
15C4VB43    271   SPO11_NOSCE Probable meiosis-specific protein...1790.002     43.1     29     44GO:0005694; C:chromosome; IEA:InterPro.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:InterPro.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
GO:0006259; P:DNA metabolic process; IEA:InterPro.::GO:0007126; P:meiosis; IEA:UniProtKB-KW.::GO:0030435; P:sporulation resulting in formation of a cellular spore; IEA:UniProtKB-KW.
16Q8PUB7    369   TOP6A_METMA Type II DNA topoisomerase VI subu...2130.003     43.1     22     44GO:0005694; C:chromosome; IEA:InterPro.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0006265; P:DNA topological change; IEA:InterPro.
17Q8TQF8    373   TOP6A_METAC Type II DNA topoisomerase VI subu...1990.003     43.1     22     45GO:0005694; C:chromosome; IEA:InterPro.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0006265; P:DNA topological change; IEA:InterPro.
18Q3IPW7    368   TOP6A_NATPD Type 2 DNA topoisomerase 6 subuni...2340.012     41.2     22     40GO:0005694; C:chromosome; IEA:InterPro.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0006265; P:DNA topological change; IEA:InterPro.
19Q9HR32    366   TOP6A_HALSA Type II DNA topoisomerase VI subu...2280.044     39.3     22     40GO:0005694; C:chromosome; IEA:InterPro.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0006265; P:DNA topological change; IEA:InterPro.
20B0R4D2    366   TOP6A_HALS3 Type 2 DNA topoisomerase 6 subuni...2280.044     39.3     22     40GO:0005694; C:chromosome; IEA:InterPro.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0006265; P:DNA topological change; IEA:InterPro.
21Q57815    369   TOP6A_METJA Type II DNA topoisomerase VI subu...660.2     37.4     33     55GO:0005694; C:chromosome; IEA:InterPro.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0006265; P:DNA topological change; IEA:InterPro.
22Q5V4R4    368   TOP6A_HALMA Type II DNA topoisomerase VI subu...2330.36     36.6     21     43GO:0005694; C:chromosome; IEA:InterPro.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0006265; P:DNA topological change; IEA:InterPro.
23Q13CR0    274   PSTB_RHOPS Phosphate import ATP-binding prote...911.6     34.3     29     51GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005315; F:inorganic phosphate transmembrane transporter activity; IEA:InterPro.::GO:0015415; F:phosphate ion transmembrane-transporting ATPase activity; IEA:EC.
24Q1QQH1    272   PSTB_NITHX Phosphate import ATP-binding prote...322.4     33.5     47     72GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005315; F:inorganic phosphate transmembrane transporter activity; IEA:InterPro.::GO:0015415; F:phosphate ion transmembrane-transporting ATPase activity; IEA:EC.
25Q6N0I5    273   PSTB_RHOPA Phosphate import ATP-binding prote...912.4     33.5     32     51GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005315; F:inorganic phosphate transmembrane transporter activity; IEA:InterPro.::GO:0015415; F:phosphate ion transmembrane-transporting ATPase activity; IEA:EC.
26Q9XBG1    261   PSTB_BURSP Phosphate import ATP-binding prote...682.8     33.5     31     57GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005315; F:inorganic phosphate transmembrane transporter activity; IEA:InterPro.::GO:0015415; F:phosphate ion transmembrane-transporting ATPase activity; IEA:EC.
27Q3SVB5    273   PSTB_NITWN Phosphate import ATP-binding prote...913.7     33.1     30     51GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005315; F:inorganic phosphate transmembrane transporter activity; IEA:InterPro.::GO:0015415; F:phosphate ion transmembrane-transporting ATPase activity; IEA:EC.
28Q2J220    274   PSTB_RHOP2 Phosphate import ATP-binding prote...675.2     32.7     34     58GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005315; F:inorganic phosphate transmembrane transporter activity; IEA:InterPro.::GO:0015415; F:phosphate ion transmembrane-transporting ATPase activity; IEA:EC.
29P40186    285   PCL7_YEAST PHO85 cyclin-7 OS=Saccharomyces ce...836.8     32.3     28     46GO:0000307; C:cyclin-dependent protein kinase holoenzyme complex; IPI:SGD.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IDA:SGD.
GO:0016538; F:cyclin-dependent protein kinase regulator activity; IDA:SGD.::GO:0019901; F:protein kinase binding; IEA:InterPro.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0005977; P:glycogen metabolic process; IEA:UniProtKB-KW.::GO:0000079; P:regulation of cyclin-dependent protein kinase activity; IDA:SGD.::GO:0031647; P:regulation of protein stability; IMP:SGD.
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