Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YHL011C
Length:
320
Number of sequences:
5887
Description:
YHL011C PRS3 SGDID:S000001003, Chr VIII from 81616-80654, Genome Release 64-1-1, reverse complement, Verified ORF, "5-phospho-ribosyl-1(alpha)-pyrophosphate synthetase, synthesizes PRPP, which is required for nucleotide, histidine, and tryptophan biosynthesis; one of five related enzymes, which are active as heteromultimeric complexes"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
1P38689    320   KPR3_YEAST Ribose-phosphate pyrophosphokinase...3200     650     100     100GO:0005737; C:cytoplasm; IDA:SGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016301; F:kinase activity; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004749; F:ribose phosphate diphosphokinase activity; IEA:EC.
GO:0006015; P:5-phosphoribose 1-diphosphate biosynthetic process; IMP:SGD.::GO:0031505; P:fungal-type cell wall organization; IPI:SGD.::GO:0009116; P:nucleoside metabolic process; IEA:InterPro.::GO:0008361; P:regulation of cell size; IMP:SGD.::GO:0009156; P:ribonucleoside monophosphate biosynthetic process; IEA:InterPro.
2P46585    321   KPR1_CANAX Ribose-phosphate pyrophosphokinase...3190     559     86     92
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016301; F:kinase activity; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0004749; F:ribose phosphate diphosphokinase activity; IEA:EC.
GO:0009116; P:nucleoside metabolic process; IEA:InterPro.::GO:0009156; P:ribonucleoside monophosphate biosynthetic process; IEA:InterPro.
3O94413    321   KPR2_SCHPO Ribose-phosphate pyrophosphokinase...3211e-148     428     66     81GO:0005829; C:cytosol; IDA:PomBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016301; F:kinase activity; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0004749; F:ribose phosphate diphosphokinase activity; ISS:PomBase.
GO:0009116; P:nucleoside metabolic process; IEA:InterPro.::GO:0006163; P:purine nucleotide metabolic process; NAS:PomBase.::GO:0009156; P:ribonucleoside monophosphate biosynthetic process; IEA:InterPro.
4P38620    318   KPR2_YEAST Ribose-phosphate pyrophosphokinase...3215e-146     421     63     81GO:0005737; C:cytoplasm; IDA:SGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016301; F:kinase activity; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004749; F:ribose phosphate diphosphokinase activity; IEA:EC.
GO:0006015; P:5-phosphoribose 1-diphosphate biosynthetic process; IMP:SGD.::GO:0031505; P:fungal-type cell wall organization; IPI:SGD.::GO:0009116; P:nucleoside metabolic process; IEA:InterPro.::GO:0009156; P:ribonucleoside monophosphate biosynthetic process; IEA:InterPro.
5P38063    326   KPR4_YEAST Ribose-phosphate pyrophosphokinase...3214e-144     416     64     80GO:0005737; C:cytoplasm; IDA:SGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016301; F:kinase activity; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0004749; F:ribose phosphate diphosphokinase activity; IEA:EC.
GO:0006015; P:5-phosphoribose 1-diphosphate biosynthetic process; IMP:SGD.::GO:0031505; P:fungal-type cell wall organization; IPI:SGD.::GO:0009116; P:nucleoside metabolic process; IEA:InterPro.::GO:0009156; P:ribonucleoside monophosphate biosynthetic process; IEA:InterPro.
6Q5XGI0    318   PRPS2_XENTR Ribose-phosphate pyrophosphokinas...3215e-141     408     62     79
GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0016301; F:kinase activity; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.::GO:0004749; F:ribose phosphate diphosphokinase activity; ISS:UniProtKB.
GO:0009116; P:nucleoside metabolic process; IEA:InterPro.::GO:0009156; P:ribonucleoside monophosphate biosynthetic process; IEA:InterPro.
7Q7ZXC9    318   PRPS2_XENLA Ribose-phosphate pyrophosphokinas...3217e-140     405     61     79
GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0016301; F:kinase activity; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.::GO:0004749; F:ribose phosphate diphosphokinase activity; ISS:UniProtKB.
GO:0009116; P:nucleoside metabolic process; IEA:InterPro.::GO:0009156; P:ribonucleoside monophosphate biosynthetic process; IEA:InterPro.
8P09330    318   PRPS2_RAT Ribose-phosphate pyrophosphokinase ...3212e-139     404     61     78GO:0002189; C:ribose phosphate diphosphokinase complex; IDA:RGD.::GO:0005625; C:soluble fraction; IDA:RGD.
GO:0043531; F:ADP binding; IDA:RGD.::GO:0016208; F:AMP binding; IDA:RGD.::GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0030246; F:carbohydrate binding; IDA:RGD.::GO:0019003; F:GDP binding; IDA:RGD.::GO:0016301; F:kinase activity; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IDA:RGD.::GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.::GO:0004749; F:ribose phosphate diphosphokinase activity; ISS:UniProtKB.
GO:0006015; P:5-phosphoribose 1-diphosphate biosynthetic process; IDA:RGD.::GO:0006167; P:AMP biosynthetic process; IDA:RGD.::GO:0009116; P:nucleoside metabolic process; IEA:InterPro.::GO:0031100; P:organ regeneration; IEP:RGD.
9Q5R8F8    318   PRPS2_PONAB Ribose-phosphate pyrophosphokinas...3212e-139     404     61     78
GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0016301; F:kinase activity; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.::GO:0004749; F:ribose phosphate diphosphokinase activity; ISS:UniProtKB.
GO:0009116; P:nucleoside metabolic process; IEA:InterPro.::GO:0009156; P:ribonucleoside monophosphate biosynthetic process; IEA:InterPro.
10Q4R4R7    318   PRPS2_MACFA Ribose-phosphate pyrophosphokinas...3212e-139     404     61     78
GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0016301; F:kinase activity; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.::GO:0004749; F:ribose phosphate diphosphokinase activity; ISS:UniProtKB.
GO:0009116; P:nucleoside metabolic process; IEA:InterPro.::GO:0009156; P:ribonucleoside monophosphate biosynthetic process; IEA:InterPro.
11P11908    318   PRPS2_HUMAN Ribose-phosphate pyrophosphokinas...3212e-139     404     61     78
GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0016301; F:kinase activity; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.::GO:0004749; F:ribose phosphate diphosphokinase activity; ISS:UniProtKB.
GO:0009116; P:nucleoside metabolic process; IEA:InterPro.::GO:0009156; P:ribonucleoside monophosphate biosynthetic process; IEA:InterPro.
12Q9CS42    318   PRPS2_MOUSE Ribose-phosphate pyrophosphokinas...3211e-138     402     61     78
GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0016301; F:kinase activity; IEA:UniProtKB-KW.::GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.::GO:0004749; F:ribose phosphate diphosphokinase activity; ISS:UniProtKB.
GO:0009116; P:nucleoside metabolic process; IEA:InterPro.
13P60892    318   PRPS1_RAT Ribose-phosphate pyrophosphokinase ...3212e-138     402     60     79GO:0002189; C:ribose phosphate diphosphokinase complex; IDA:RGD.::GO:0005625; C:soluble fraction; IDA:RGD.
GO:0043531; F:ADP binding; IDA:RGD.::GO:0016208; F:AMP binding; IDA:RGD.::GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0030246; F:carbohydrate binding; IDA:RGD.::GO:0019003; F:GDP binding; IDA:RGD.::GO:0016301; F:kinase activity; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IDA:RGD.::GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.::GO:0004749; F:ribose phosphate diphosphokinase activity; ISS:UniProtKB.
GO:0006015; P:5-phosphoribose 1-diphosphate biosynthetic process; IDA:RGD.::GO:0006167; P:AMP biosynthetic process; IDA:RGD.::GO:0009116; P:nucleoside metabolic process; IEA:InterPro.::GO:0031100; P:organ regeneration; IEP:RGD.
14Q5RFJ7    318   PRPS1_PONAB Ribose-phosphate pyrophosphokinas...3212e-138     402     60     79
GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0016301; F:kinase activity; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.::GO:0004749; F:ribose phosphate diphosphokinase activity; ISS:UniProtKB.
GO:0009116; P:nucleoside metabolic process; IEA:InterPro.::GO:0009156; P:ribonucleoside monophosphate biosynthetic process; IEA:InterPro.
15Q9D7G0    318   PRPS1_MOUSE Ribose-phosphate pyrophosphokinas...3212e-138     402     60     79
GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0016301; F:kinase activity; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.::GO:0004749; F:ribose phosphate diphosphokinase activity; ISS:UniProtKB.
GO:0009116; P:nucleoside metabolic process; IEA:InterPro.::GO:0009156; P:ribonucleoside monophosphate biosynthetic process; IEA:InterPro.
16P60891    318   PRPS1_HUMAN Ribose-phosphate pyrophosphokinas...3212e-138     402     60     79GO:0005829; C:cytosol; TAS:Reactome.
GO:0005524; F:ATP binding; IDA:UniProtKB.::GO:0016301; F:kinase activity; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0042803; F:protein homodimerization activity; IPI:UniProtKB.::GO:0004749; F:ribose phosphate diphosphokinase activity; IDA:UniProtKB.
GO:0006015; P:5-phosphoribose 1-diphosphate biosynthetic process; TAS:Reactome.::GO:0046101; P:hypoxanthine biosynthetic process; IMP:UniProtKB.::GO:0007399; P:nervous system development; IMP:UniProtKB.::GO:0009116; P:nucleoside metabolic process; IEA:InterPro.::GO:0006164; P:purine nucleotide biosynthetic process; IMP:UniProtKB.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; NAS:UniProtKB.::GO:0009156; P:ribonucleoside monophosphate biosynthetic process; IEA:InterPro.::GO:0034418; P:urate biosynthetic process; IMP:UniProtKB.
17Q2HJ58    318   PRPS1_BOVIN Ribose-phosphate pyrophosphokinas...3212e-138     402     60     79
GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0016301; F:kinase activity; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.::GO:0004749; F:ribose phosphate diphosphokinase activity; ISS:UniProtKB.
GO:0009116; P:nucleoside metabolic process; IEA:InterPro.::GO:0009156; P:ribonucleoside monophosphate biosynthetic process; IEA:InterPro.
18Q4R4U3    318   PRPS1_MACFA Ribose-phosphate pyrophosphokinas...3217e-138     400     60     78
GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0016301; F:kinase activity; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.::GO:0004749; F:ribose phosphate diphosphokinase activity; ISS:UniProtKB.
GO:0009116; P:nucleoside metabolic process; IEA:InterPro.::GO:0009156; P:ribonucleoside monophosphate biosynthetic process; IEA:InterPro.
19Q5ZI49    325   PRPS2_CHICK Ribose-phosphate pyrophosphokinas...3289e-138     400     60     76
GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0016301; F:kinase activity; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.::GO:0004749; F:ribose phosphate diphosphokinase activity; ISS:UniProtKB.
GO:0009116; P:nucleoside metabolic process; IEA:InterPro.::GO:0009156; P:ribonucleoside monophosphate biosynthetic process; IEA:InterPro.
20P21108    318   PRPS3_HUMAN Ribose-phosphate pyrophosphokinas...3217e-132     385     59     77
GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0016301; F:kinase activity; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.::GO:0004749; F:ribose phosphate diphosphokinase activity; ISS:UniProtKB.
GO:0009116; P:nucleoside metabolic process; IEA:InterPro.::GO:0009156; P:ribonucleoside monophosphate biosynthetic process; NAS:UniProtKB.
21Q54PA9    317   PRPSA_DICDI Ribose-phosphate pyrophosphokinas...3124e-122     360     56     74GO:0045335; C:phagocytic vesicle; IDA:dictyBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016301; F:kinase activity; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0004749; F:ribose phosphate diphosphokinase activity; IEA:EC.
GO:0000105; P:histidine biosynthetic process; ISS:dictyBase.::GO:0009116; P:nucleoside metabolic process; IEA:InterPro.::GO:0009617; P:response to bacterium; IEP:dictyBase.::GO:0009156; P:ribonucleoside monophosphate biosynthetic process; IEA:InterPro.::GO:0000162; P:tryptophan biosynthetic process; ISS:dictyBase.
22Q6AJL7    313   KPRS_DESPS Ribose-phosphate pyrophosphokinase...3154e-95     291     47     67GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016301; F:kinase activity; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0004749; F:ribose phosphate diphosphokinase activity; IEA:EC.
GO:0009116; P:nucleoside metabolic process; IEA:InterPro.::GO:0009156; P:ribonucleoside monophosphate biosynthetic process; IEA:InterPro.
23Q54QU9    321   PRPSC_DICDI Ribose-phosphate pyrophosphokinas...3091e-94     290     45     72GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016301; F:kinase activity; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0004749; F:ribose phosphate diphosphokinase activity; IEA:EC.
GO:0000105; P:histidine biosynthetic process; ISS:dictyBase.::GO:0009165; P:nucleotide biosynthetic process; IEA:UniProtKB-KW.::GO:0000162; P:tryptophan biosynthetic process; ISS:dictyBase.
24Q97E93    319   KPRS_CLOAB Ribose-phosphate pyrophosphokinase...3132e-90     279     48     66GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016301; F:kinase activity; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0004749; F:ribose phosphate diphosphokinase activity; IEA:EC.
GO:0009116; P:nucleoside metabolic process; IEA:InterPro.::GO:0009156; P:ribonucleoside monophosphate biosynthetic process; IEA:InterPro.
25P44328    315   KPRS_HAEIN Ribose-phosphate pyrophosphokinase...3175e-89     275     48     66GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016301; F:kinase activity; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0004749; F:ribose phosphate diphosphokinase activity; IEA:EC.
GO:0009116; P:nucleoside metabolic process; IEA:InterPro.::GO:0009156; P:ribonucleoside monophosphate biosynthetic process; IEA:InterPro.
26Q7VL55    316   KPRS_HAEDU Ribose-phosphate pyrophosphokinase...3175e-89     275     48     67GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016301; F:kinase activity; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0004749; F:ribose phosphate diphosphokinase activity; IEA:EC.
GO:0009116; P:nucleoside metabolic process; IEA:InterPro.::GO:0009156; P:ribonucleoside monophosphate biosynthetic process; IEA:InterPro.
27Q92N73    310   KPRS_RHIME Ribose-phosphate pyrophosphokinase...3106e-89     275     46     66GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016301; F:kinase activity; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0004749; F:ribose phosphate diphosphokinase activity; IEA:EC.
GO:0009116; P:nucleoside metabolic process; IEA:InterPro.::GO:0009156; P:ribonucleoside monophosphate biosynthetic process; IEA:InterPro.
28Q7NQS9    327   KPRS_CHRVO Ribose-phosphate pyrophosphokinase...3002e-88     275     48     68GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016301; F:kinase activity; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0004749; F:ribose phosphate diphosphokinase activity; IEA:EC.
GO:0009116; P:nucleoside metabolic process; IEA:InterPro.::GO:0009156; P:ribonucleoside monophosphate biosynthetic process; IEA:InterPro.
29Q0C5A1    312   KPRS_HYPNA Ribose-phosphate pyrophosphokinase...3112e-88     274     48     67GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016301; F:kinase activity; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0004749; F:ribose phosphate diphosphokinase activity; IEA:EC.
GO:0009116; P:nucleoside metabolic process; IEA:InterPro.::GO:0009156; P:ribonucleoside monophosphate biosynthetic process; IEA:InterPro.
30Q9CP22    315   KPRS_PASMU Ribose-phosphate pyrophosphokinase...3173e-88     273     48     65GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016301; F:kinase activity; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0004749; F:ribose phosphate diphosphokinase activity; IEA:EC.
GO:0009116; P:nucleoside metabolic process; IEA:InterPro.::GO:0009156; P:ribonucleoside monophosphate biosynthetic process; IEA:InterPro.
31Q8FZF0    310   KPRS_BRUSU Ribose-phosphate pyrophosphokinase...3105e-88     273     46     65GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016301; F:kinase activity; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0004749; F:ribose phosphate diphosphokinase activity; IEA:EC.
GO:0009116; P:nucleoside metabolic process; IEA:InterPro.::GO:0009156; P:ribonucleoside monophosphate biosynthetic process; IEA:InterPro.
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