Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YHL003C
Length:
411
Number of sequences:
5887
Description:
YHL003C LAG1 SGDID:S000000995, Chr VIII from 101883-100648, Genome Release 64-1-1, reverse complement, Verified ORF, "Ceramide synthase component, involved in synthesis of ceramide from C26(acyl)-coenzyme A and dihydrosphingosine or phytosphingosine, functionally equivalent to Lac1p"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
1P38703    411   LAG1_YEAST Sphingosine N-acyltransferase LAG1...4110     852     100     100GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0005515; F:protein binding; IPI:IntAct.::GO:0050291; F:sphingosine N-acyltransferase activity; IDA:SGD.
GO:0046513; P:ceramide biosynthetic process; IDA:SGD.::GO:0001302; P:replicative cell aging; IMP:SGD.
2A6ZSP9    411   LAG1_YEAS7 Sphingosine N-acyltransferase LAG1...4110     848     99     99GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0050291; F:sphingosine N-acyltransferase activity; IEA:EC.
GO:0008610; P:lipid biosynthetic process; IEA:UniProtKB-KW.
3P28496    418   LAC1_YEAST Sphingosine N-acyltransferase LAC1...3780     585     73     84GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0005515; F:protein binding; IPI:IntAct.::GO:0050291; F:sphingosine N-acyltransferase activity; IDA:SGD.
GO:0046513; P:ceramide biosynthetic process; IDA:SGD.
4A6ZZV7    418   LAC1_YEAS7 Sphingosine N-acyltransferase LAC1...3780     585     73     84GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0050291; F:sphingosine N-acyltransferase activity; IEA:EC.
GO:0008610; P:lipid biosynthetic process; IEA:UniProtKB-KW.
5O59735    384   LAC1_SCHPO Sphingosine N-acyltransferase lac1...3693e-90     284     42     60GO:0030176; C:integral to endoplasmic reticulum membrane; NAS:PomBase.::GO:0005773; C:vacuole; IMP:GOC.
GO:0050291; F:sphingosine N-acyltransferase activity; IEA:EC.
GO:0071277; P:cellular response to calcium ion; IMP:PomBase.::GO:0034605; P:cellular response to heat; IMP:PomBase.::GO:0071294; P:cellular response to zinc ion; IMP:PomBase.::GO:0046513; P:ceramide biosynthetic process; ISS:PomBase.::GO:0007126; P:meiosis; IEA:UniProtKB-KW.::GO:0007009; P:plasma membrane organization; IMP:PomBase.::GO:0042493; P:response to drug; IMP:PomBase.::GO:0009636; P:response to toxin; IGI:PomBase.::GO:0007035; P:vacuolar acidification; IMP:PomBase.::GO:0070072; P:vacuolar proton-transporting V-type ATPase complex assembly; ISS:PomBase.
6P78970    390   LAG1_SCHPO Sphingosine N-acyltransferase lag1...3037e-40     151     38     53GO:0030176; C:integral to endoplasmic reticulum membrane; NAS:PomBase.::GO:0005773; C:vacuole; IGI:GOC.
GO:0050291; F:sphingosine N-acyltransferase activity; IEA:EC.
GO:0046513; P:ceramide biosynthetic process; ISS:PomBase.::GO:0042493; P:response to drug; IMP:PomBase.::GO:0009636; P:response to toxin; IMP:PomBase.::GO:0007035; P:vacuolar acidification; IGI:PomBase.
7Q5E9R6    393   CERS4_BOVIN Ceramide synthase 4 OS=Bos taurus...2230.000000000000001     81.6     30     53GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0031965; C:nuclear membrane; IEA:UniProtKB-SubCell.
GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
8Q9D6J1    393   CERS4_MOUSE Ceramide synthase 4 OS=Mus muscul...2340.000000000000003     80.5     29     47GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0031965; C:nuclear membrane; IEA:UniProtKB-SubCell.
GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.::GO:0050291; F:sphingosine N-acyltransferase activity; IDA:MGI.
GO:0046513; P:ceramide biosynthetic process; IDA:MGI.
9Q6NQI8    308   LAG13_ARATH LAG1 longevity assurance homolog ...2990.0000000000002     74.3     27     43GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0050291; F:sphingosine N-acyltransferase activity; IGI:TAIR.
GO:0042761; P:very long-chain fatty acid biosynthetic process; IGI:TAIR.
10Q9LJK3    296   LAG12_ARATH LAG1 longevity assurance homolog ...2280.00000000002     67.8     25     46GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005794; C:Golgi apparatus; IDA:TAIR.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IDA:TAIR.
GO:0050291; F:sphingosine N-acyltransferase activity; IMP:TAIR.
GO:0042759; P:long-chain fatty acid biosynthetic process; IMP:TAIR.::GO:0002238; P:response to molecule of fungal origin; IMP:TAIR.
11Q6EUN0    309   ASCL1_ORYSJ ASC1-like protein 1 OS=Oryza sati...2040.0000000008     63.2     28     46GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0008610; P:lipid biosynthetic process; IEA:UniProtKB-KW.
12Q9HA82    394   CERS4_HUMAN Ceramide synthase 4 OS=Homo sapie...2320.000000001     63.2     30     49GO:0005789; C:endoplasmic reticulum membrane; TAS:Reactome.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0031965; C:nuclear membrane; IEA:UniProtKB-SubCell.
GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
GO:0044281; P:small molecule metabolic process; TAS:Reactome.
13Q9LDF2    310   LAG11_ARATH LAG1 longevity assurance homolog ...3010.000000002     62     24     43GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005794; C:Golgi apparatus; IDA:TAIR.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IDA:TAIR.
GO:0008610; P:lipid biosynthetic process; IEA:UniProtKB-KW.
14Q96G23    380   CERS2_HUMAN Ceramide synthase 2 OS=Homo sapie...1970.000000005     61.2     26     48GO:0005789; C:endoplasmic reticulum membrane; TAS:Reactome.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0031965; C:nuclear membrane; IDA:HPA.
GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
GO:0044281; P:small molecule metabolic process; TAS:Reactome.
15Q84QC0    284   ASCL3_ORYSJ ASC1-like protein 3 OS=Oryza sati...2720.000000005     60.5     26     44GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0008610; P:lipid biosynthetic process; IEA:UniProtKB-KW.
16Q3ZBF8    380   CERS2_BOVIN Ceramide synthase 2 OS=Bos taurus...1970.00000002     59.7     25     48GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0031965; C:nuclear membrane; IEA:UniProtKB-SubCell.
GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
17Q924Z4    380   CERS2_MOUSE Ceramide synthase 2 OS=Mus muscul...2080.00000004     58.2     25     45GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0031965; C:nuclear membrane; IEA:UniProtKB-SubCell.
GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.::GO:0050291; F:sphingosine N-acyltransferase activity; IDA:MGI.
GO:0046513; P:ceramide biosynthetic process; IDA:MGI.
18Q6YWS8    303   ASCL2_ORYSJ ASC1-like protein 2 OS=Oryza sati...1810.0000003     55.1     28     46GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0008610; P:lipid biosynthetic process; IEA:UniProtKB-KW.
19Q6DED0    373   TR1L1_XENLA Translocating chain-associated me...2010.000003     52.8     25     42GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0015031; P:protein transport; IEA:UniProtKB-KW.
20Q8W4Y5    303   ASCL_SOLLC ASC1-like protein OS=Solanum lycop...2490.000005     51.6     24     41GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0008610; P:lipid biosynthetic process; IEA:UniProtKB-KW.
21P27545    350   CERS1_MOUSE Ceramide synthase 1 OS=Mus muscul...770.00004     48.9     38     56GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005792; C:microsome; IDA:HGNC.
GO:0050291; F:sphingosine N-acyltransferase activity; IDA:HGNC.
GO:0046513; P:ceramide biosynthetic process; IDA:HGNC.
22Q9M6A3    308   ASC1_SOLLC Protein ASC1 OS=Solanum lycopersic...1640.00007     48.1     27     50GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0008610; P:lipid biosynthetic process; IEA:UniProtKB-KW.
23Q8QZR0    363   TR1L1_MOUSE Translocating chain-associated me...1060.0002     46.6     29     50GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0015031; P:protein transport; IEA:UniProtKB-KW.
24Q5XI41    374   TRAM1_RAT Translocating chain-associated memb...1570.0005     45.8     29     43GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0015031; P:protein transport; IEA:UniProtKB-KW.
25Q01685    374   TRAM1_CANFA Translocating chain-associated me...1570.0006     45.4     27     44GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0015031; P:protein transport; IEA:UniProtKB-KW.
26Q15629    374   TRAM1_HUMAN Translocating chain-associated me...1570.0008     44.7     29     44GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; TAS:ProtInc.
GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004872; F:receptor activity; TAS:ProtInc.
GO:0006614; P:SRP-dependent cotranslational protein targeting to membrane; TAS:Reactome.::GO:0006412; P:translation; TAS:Reactome.
27Q6ZMG9    384   CERS6_HUMAN Ceramide synthase 6 OS=Homo sapie...1490.001     44.7     28     48GO:0005789; C:endoplasmic reticulum membrane; TAS:Reactome.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0031965; C:nuclear membrane; IEA:UniProtKB-SubCell.
GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
GO:0044281; P:small molecule metabolic process; TAS:Reactome.::GO:0030148; P:sphingolipid biosynthetic process; TAS:Reactome.
28P27544    350   CERS1_HUMAN Ceramide synthase 1 OS=Homo sapie...2870.001     44.7     24     39GO:0005789; C:endoplasmic reticulum membrane; TAS:Reactome.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005792; C:microsome; ISS:HGNC.
GO:0050291; F:sphingosine N-acyltransferase activity; ISS:HGNC.
GO:0046513; P:ceramide biosynthetic process; ISS:HGNC.::GO:0044281; P:small molecule metabolic process; TAS:Reactome.
29Q5R7Z3    374   TRAM1_PONAB Translocating chain-associated me...1570.001     44.3     29     44GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0015031; P:protein transport; IEA:UniProtKB-KW.
30Q91V04    374   TRAM1_MOUSE Translocating chain-associated me...1570.001     44.3     29     44GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0015031; P:protein transport; IEA:UniProtKB-KW.
31Q9GKZ4    374   TRAM1_BOVIN Translocating chain-associated me...1570.002     43.5     28     45GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0015031; P:protein transport; IEA:UniProtKB-KW.
records
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