Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YHL002W
Length:
452
Number of sequences:
5887
Description:
YHL002W HSE1 SGDID:S000000994, Chr VIII from 102612-103970, Genome Release 64-1-1, Verified ORF, "Subunit of the endosomal Vps27p-Hse1p complex required for sorting of ubiquitinated membrane proteins into intralumenal vesicles prior to vacuolar degradation, as well as for recycling of Golgi proteins and formation of lumenal membranes"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
91O08641    340   SH3Y1_MOUSE SH3 domain-containing YSC84-like ...530.00000005     58.2     49     62
GO:0005515; F:protein binding; IPI:IntAct.
92P49710    486   HCLS1_MOUSE Hematopoietic lineage cell-specif...470.00000005     58.5     51     62GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IDA:UniProtKB.
GO:0032403; F:protein complex binding; IPI:MGI.::GO:0017124; F:SH3 domain binding; IDA:MGI.
GO:0030218; P:erythrocyte differentiation; IMP:UniProtKB.::GO:0008284; P:positive regulation of cell proliferation; IMP:UniProtKB.::GO:0042531; P:positive regulation of tyrosine phosphorylation of STAT protein; IMP:UniProtKB.::GO:0009725; P:response to hormone stimulus; IDA:UniProtKB.
93Q99961    368   SH3G1_HUMAN Endophilin-A2 OS=Homo sapiens (Hu...540.00000005     58.2     44     61GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell.
GO:0008289; F:lipid binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0007417; P:central nervous system development; TAS:ProtInc.::GO:0006897; P:endocytosis; IEA:UniProtKB-KW.::GO:0007165; P:signal transduction; TAS:ProtInc.
94Q6DFH5    335   SH3Y1_XENLA SH3 domain-containing YSC84-like ...2150.00000006     58.2     25     41
95Q8MJ50    214   OSTF1_BOVIN Osteoclast-stimulating factor 1 O...580.00000006     56.6     41     55GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
96P34109    1109   MYOD_DICDI Myosin ID heavy chain OS=Dictyoste...610.00000007     58.5     44     57GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell.::GO:0031252; C:cell leading edge; IDA:dictyBase.::GO:0016459; C:myosin complex; IEA:UniProtKB-KW.::GO:0031143; C:pseudopodium; IEA:UniProtKB-SubCell.
GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003774; F:motor activity; IEA:InterPro.
GO:0006935; P:chemotaxis; IEA:UniProtKB-KW.::GO:0006909; P:phagocytosis; IEA:UniProtKB-KW.
97Q2KJA1    368   SH3G1_BOVIN Endophilin-A2 OS=Bos taurus (Bovi...540.00000007     57.8     43     61GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell.
GO:0008289; F:lipid binding; IEA:UniProtKB-KW.
GO:0006897; P:endocytosis; IEA:UniProtKB-KW.
98A5D8S5    867   SH3R1_DANRE E3 ubiquitin-protein ligase SH3RF...590.39     37     31     51GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0030027; C:lamellipodium; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
99Q6XJU9    214   OSTF1_MONAL Osteoclast-stimulating factor 1 O...970.00000008     56.2     28     49GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
100Q8AXU9    353   SH3G3_CHICK Endophilin-A3 OS=Gallus gallus (C...540.00000009     57.4     43     61GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell.
GO:0008289; F:lipid binding; IEA:UniProtKB-KW.
GO:0006897; P:endocytosis; IEA:UniProtKB-KW.
101Q62422    215   OSTF1_MOUSE Osteoclast-stimulating factor 1 O...580.00000009     55.8     41     53GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0017124; F:SH3 domain binding; IDA:MGI.
102Q6P686    214   OSTF1_RAT Osteoclast-stimulating factor 1 OS=...580.00000009     55.8     41     53GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
103Q9Y5K6    639   CD2AP_HUMAN CD2-associated protein OS=Homo sa...500.12     38.5     36     58GO:0005737; C:cytoplasm; IDA:HPA.::GO:0031941; C:filamentous actin; IDA:UniProtKB.::GO:0005730; C:nucleolus; IDA:HPA.::GO:0005886; C:plasma membrane; IDA:HPA.::GO:0001726; C:ruffle; IDA:UniProtKB.
GO:0017124; F:SH3 domain binding; IPI:UniProtKB.::GO:0005200; F:structural constituent of cytoskeleton; TAS:ProtInc.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0006461; P:protein complex assembly; TAS:ProtInc.::GO:0007165; P:signal transduction; NAS:ProtInc.::GO:0006930; P:substrate-dependent cell migration, cell extension; TAS:ProtInc.
104Q9Z0R6    1659   ITSN2_MOUSE Intersectin-2 OS=Mus musculus (Mo...500.0002     47.8     44     62GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro.
GO:0006897; P:endocytosis; IEA:UniProtKB-KW.::GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro.
105Q6TGW5    214   OSTF1_DANRE Osteoclast-stimulating factor 1 O...970.0000001     55.8     28     49GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
106Q8VCZ6    750   SGSM3_MOUSE Small G protein signaling modulat...1260.0000001     57.8     29     48GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005921; C:gap junction; IDA:UniProtKB.
GO:0005097; F:Rab GTPase activator activity; IEA:InterPro.::GO:0017137; F:Rab GTPase binding; ISS:UniProtKB.
GO:0007050; P:cell cycle arrest; IEA:UniProtKB-KW.::GO:0045732; P:positive regulation of protein catabolic process; IDA:UniProtKB.::GO:0032486; P:Rap protein signal transduction; ISS:UniProtKB.
107P97306    403   STAC_MOUSE SH3 and cysteine-rich domain-conta...820.0000001     57.4     37     51GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0034605; P:cellular response to heat; IDA:MGI.::GO:0035556; P:intracellular signal transduction; IEA:InterPro.
108O13154    448   PACN2_CHICK Protein kinase C and casein kinas...560.0000001     57.4     52     66GO:0005829; C:cytosol; ISS:AgBase.::GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell.
GO:0008092; F:cytoskeletal protein binding; ISS:AgBase.
GO:0006897; P:endocytosis; IEA:UniProtKB-KW.::GO:0045806; P:negative regulation of endocytosis; ISS:AgBase.
109Q6P6R7    749   SGSM3_RAT Small G protein signaling modulator...1260.0000001     57.8     29     48GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005097; F:Rab GTPase activator activity; IEA:InterPro.::GO:0017137; F:Rab GTPase binding; ISS:UniProtKB.
GO:0007050; P:cell cycle arrest; IEA:UniProtKB-KW.::GO:0032486; P:Rap protein signal transduction; ISS:UniProtKB.
110Q6NRD3    826   SH3R1_XENLA E3 ubiquitin-protein ligase SH3RF...550.79     35.8     29     51GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0030027; C:lamellipodium; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
111A0JNJ1    403   STAC_BOVIN SH3 and cysteine-rich domain-conta...660.0000001     57     41     56GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0035556; P:intracellular signal transduction; IEA:InterPro.
112Q7ZYG4    214   OSTF1_XENLA Osteoclast-stimulating factor 1 O...580.0000001     55.5     40     55GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
113Q96HU1    749   SGSM3_HUMAN Small G protein signaling modulat...1250.0000001     57.8     29     49GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005097; F:Rab GTPase activator activity; IEA:InterPro.::GO:0017137; F:Rab GTPase binding; IDA:UniProtKB.
GO:0007050; P:cell cycle arrest; IEA:UniProtKB-KW.::GO:0032486; P:Rap protein signal transduction; IEP:UniProtKB.
114P97369    339   NCF4_MOUSE Neutrophil cytosol factor 4 OS=Mus...510.0000001     57     47     67GO:0005737; C:cytoplasm; IDA:MGI.
GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:MGI.
GO:0007154; P:cell communication; IEA:InterPro.
115P56945    870   BCAR1_HUMAN Breast cancer anti-estrogen resis...570.0000001     57.8     49     61GO:0005829; C:cytosol; TAS:Reactome.::GO:0005925; C:focal adhesion; ISS:UniProtKB.::GO:0005624; C:membrane fraction; IDA:UniProtKB.::GO:0001726; C:ruffle; IDA:UniProtKB.
GO:0019901; F:protein kinase binding; IPI:UniProtKB.::GO:0019903; F:protein phosphatase binding; IPI:UniProtKB.::GO:0017124; F:SH3 domain binding; IEA:UniProtKB-KW.::GO:0004871; F:signal transducer activity; TAS:ProtInc.
GO:0007015; P:actin filament organization; IDA:UniProtKB.::GO:0050853; P:B cell receptor signaling pathway; IDA:UniProtKB.::GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.::GO:0060326; P:cell chemotaxis; IMP:BHF-UCL.::GO:0051301; P:cell division; NAS:UniProtKB.::GO:0008283; P:cell proliferation; TAS:ProtInc.::GO:0035729; P:cellular response to hepatocyte growth factor stimulus; IMP:BHF-UCL.::GO:0007173; P:epidermal growth factor receptor signaling pathway; ISS:UniProtKB.::GO:0007186; P:G-protein coupled receptor signaling pathway; ISS:UniProtKB.::GO:0048012; P:hepatocyte growth factor receptor signaling pathway; IMP:BHF-UCL.::GO:0008286; P:insulin receptor signaling pathway; ISS:UniProtKB.::GO:0007229; P:integrin-mediated signaling pathway; IDA:UniProtKB.::GO:0048011; P:nerve growth factor receptor signaling pathway; ISS:UniProtKB.::GO:0030168; P:platelet activation; TAS:Reactome.::GO:0048008; P:platelet-derived growth factor receptor signaling pathway; ISS:UniProtKB.::GO:0030335; P:positive regulation of cell migration; IDA:UniProtKB.::GO:0042981; P:regulation of apoptotic process; TAS:UniProtKB.::GO:0001558; P:regulation of cell growth; TAS:UniProtKB.::GO:0050852; P:T cell receptor signaling pathway; NAS:UniProtKB.::GO:0048010; P:vascular endothelial growth factor receptor signaling pathway; IMP:BHF-UCL.
116Q9CX99    217   GRAP_MOUSE GRB2-related adapter protein OS=Mu...490.0007     44.7     43     59
117Q8MJ49    214   OSTF1_PIG Osteoclast-stimulating factor 1 OS=...580.0000002     55.1     41     55GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
118Q92882    214   OSTF1_HUMAN Osteoclast-stimulating factor 1 O...580.0000002     55.1     41     55GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0001503; P:ossification; TAS:ProtInc.::GO:0007165; P:signal transduction; TAS:ProtInc.
119P14317    486   HCLS1_HUMAN Hematopoietic lineage cell-specif...480.0000002     57     50     60GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; ISS:UniProtKB.::GO:0005886; C:plasma membrane; IDA:HPA.
GO:0003677; F:DNA binding; TAS:ProtInc.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.
GO:0030218; P:erythrocyte differentiation; ISS:UniProtKB.::GO:0035556; P:intracellular signal transduction; TAS:ProtInc.::GO:0008284; P:positive regulation of cell proliferation; ISS:UniProtKB.::GO:0042531; P:positive regulation of tyrosine phosphorylation of STAT protein; ISS:UniProtKB.::GO:0009725; P:response to hormone stimulus; ISS:UniProtKB.
120Q99469    402   STAC_HUMAN SH3 and cysteine-rich domain-conta...480.0000002     56.6     46     63GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005625; C:soluble fraction; TAS:ProtInc.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0035556; P:intracellular signal transduction; IEA:InterPro.
121Q10199    670   IMP2_SCHPO Septation protein imp2 OS=Schizosa...640.0000002     57     44     56GO:0005826; C:actomyosin contractile ring; IDA:PomBase.::GO:0005829; C:cytosol; IDA:PomBase.
GO:0005515; F:protein binding; IPI:PomBase.
GO:0000915; P:cytokinesis, actomyosin contractile ring assembly; IMP:PomBase.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.
records
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