Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YHL002W
Length:
452
Number of sequences:
5887
Description:
YHL002W HSE1 SGDID:S000000994, Chr VIII from 102612-103970, Genome Release 64-1-1, Verified ORF, "Subunit of the endosomal Vps27p-Hse1p complex required for sorting of ubiquitinated membrane proteins into intralumenal vesicles prior to vacuolar degradation, as well as for recycling of Golgi proteins and formation of lumenal membranes"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
61A4FU49    640   SH321_HUMAN SH3 domain-containing protein 21 ...530.000000005     62     45     62
62Q8AXV0    367   SH3G1_CHICK Endophilin-A2 OS=Gallus gallus (C...700.000000006     61.2     39     57GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell.
GO:0008289; F:lipid binding; IEA:UniProtKB-KW.
GO:0006897; P:endocytosis; IEA:UniProtKB-KW.
63P87379    229   GRB2A_XENLA Growth factor receptor-bound prot...550.0001     47     42     56GO:0005768; C:endosome; ISS:UniProtKB.::GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0005154; F:epidermal growth factor receptor binding; ISS:UniProtKB.::GO:0043560; F:insulin receptor substrate binding; ISS:UniProtKB.
GO:0007143; P:female meiosis; IDA:UniProtKB.::GO:0008286; P:insulin receptor signaling pathway; ISS:UniProtKB.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
64Q68FJ8    507   TM1L2_XENLA TOM1-like protein 2 OS=Xenopus la...1310.000000006     61.6     24     56GO:0005622; C:intracellular; IEA:InterPro.
GO:0006886; P:intracellular protein transport; IEA:InterPro.
65Q15811    1721   ITSN1_HUMAN Intersectin-1 OS=Homo sapiens (Hu...1080.028     40.8     31     45GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005905; C:coated pit; IDA:UniProtKB.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0030027; C:lamellipodium; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IDA:UniProtKB.::GO:0045202; C:synapse; IEA:UniProtKB-KW.::GO:0019717; C:synaptosome; IEA:UniProtKB-SubCell.
GO:0005509; F:calcium ion binding; NAS:UniProtKB.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0070064; F:proline-rich region binding; IPI:UniProtKB.::GO:0032947; F:protein complex scaffold; IDA:UniProtKB.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro.
GO:0006915; P:apoptotic process; TAS:Reactome.::GO:0008624; P:induction of apoptosis by extracellular signals; TAS:Reactome.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.::GO:0048488; P:synaptic vesicle endocytosis; TAS:ProtInc.
66P29355    228   SEM5_CAEEL Sex muscle abnormal protein 5 OS=C...490.007     41.6     41     57
GO:0016477; P:cell migration; IMP:WormBase.::GO:0008340; P:determination of adult lifespan; IMP:WormBase.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0040035; P:hermaphrodite genitalia development; IMP:WormBase.::GO:0019915; P:lipid storage; IMP:WormBase.::GO:0030539; P:male genitalia development; IMP:WormBase.::GO:0007517; P:muscle organ development; IMP:WormBase.::GO:0040015; P:negative regulation of multicellular organism growth; IMP:WormBase.::GO:0002119; P:nematode larval development; IMP:WormBase.::GO:0040010; P:positive regulation of growth rate; IMP:WormBase.::GO:0006898; P:receptor-mediated endocytosis; IMP:WormBase.::GO:0031344; P:regulation of cell projection organization; IMP:WormBase.::GO:0040028; P:regulation of vulval development; IMP:WormBase.::GO:0032940; P:secretion by cell; IMP:WormBase.
67Q13588    217   GRAP_HUMAN GRB2-related adapter protein OS=Ho...490.0009     44.3     43     59GO:0005829; C:cytosol; TAS:Reactome.
GO:0005070; F:SH3/SH2 adaptor activity; TAS:ProtInc.
GO:0007267; P:cell-cell signaling; TAS:ProtInc.::GO:0007265; P:Ras protein signal transduction; TAS:ProtInc.
68O60784    492   TOM1_HUMAN Target of Myb protein 1 OS=Homo sa...1310.00000001     60.8     22     58GO:0005829; C:cytosol; IDA:UniProtKB.::GO:0005769; C:early endosome; IDA:UniProtKB.::GO:0016020; C:membrane; IDA:UniProtKB.
GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0006897; P:endocytosis; NAS:UniProtKB.::GO:0016197; P:endosome transport; NAS:UniProtKB.::GO:0006886; P:intracellular protein transport; IEA:InterPro.
69Q6ZVM7    507   TM1L2_HUMAN TOM1-like protein 2 OS=Homo sapie...1370.00000001     60.8     25     57GO:0005622; C:intracellular; IEA:InterPro.
GO:0006886; P:intracellular protein transport; IEA:InterPro.
70Q99963    347   SH3G3_HUMAN Endophilin-A3 OS=Homo sapiens (Hu...540.00000001     60.1     43     61GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell.
GO:0042802; F:identical protein binding; IPI:IntAct.::GO:0008289; F:lipid binding; IEA:UniProtKB-KW.
GO:0007417; P:central nervous system development; TAS:ProtInc.::GO:0006897; P:endocytosis; IEA:UniProtKB-KW.::GO:0007165; P:signal transduction; TAS:ProtInc.
71Q0V8S0    777   HGS_BOVIN Hepatocyte growth factor-regulated ...1380.00000001     60.8     23     52GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell.::GO:0032585; C:multivesicular body membrane; IEA:UniProtKB-SubCell.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0006886; P:intracellular protein transport; IEA:InterPro.
72Q5SRX1    507   TM1L2_MOUSE TOM1-like protein 2 OS=Mus muscul...1370.00000001     60.5     24     57GO:0005622; C:intracellular; IEA:InterPro.
GO:0006886; P:intracellular protein transport; IEA:InterPro.
73P43603    459   LSB3_YEAST LAS seventeen-binding protein 3 OS...880.00000002     60.1     36     49GO:0005935; C:cellular bud neck; IDA:SGD.::GO:0005739; C:mitochondrion; IDA:SGD.
GO:0005515; F:protein binding; IPI:IntAct.
GO:0051666; P:actin cortical patch localization; IMP:SGD.
74A7A261    459   LSB3_YEAS7 LAS seventeen-binding protein 3 OS...880.00000002     60.1     36     49GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
75O35964    368   SH3G1_RAT Endophilin-A2 OS=Rattus norvegicus ...540.00000002     59.7     44     63GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell.::GO:0005626; C:insoluble fraction; IDA:RGD.::GO:0005625; C:soluble fraction; IDA:RGD.
GO:0051020; F:GTPase binding; IPI:RGD.::GO:0008289; F:lipid binding; IEA:UniProtKB-KW.::GO:0019902; F:phosphatase binding; IPI:RGD.
GO:0006897; P:endocytosis; IEA:UniProtKB-KW.
76Q62419    368   SH3G1_MOUSE Endophilin-A2 OS=Mus musculus (Mo...540.00000002     59.7     44     63GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell.
GO:0008289; F:lipid binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:MGI.
GO:0006897; P:endocytosis; IEA:UniProtKB-KW.
77Q7TSG5    549   SH321_MOUSE SH3 domain-containing protein 21 ...540.00000002     60.1     43     61
78Q9JJ50    776   HGS_RAT Hepatocyte growth factor-regulated ty...1380.00000002     60.5     22     52GO:0005829; C:cytosol; IDA:RGD.::GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell.::GO:0032585; C:multivesicular body membrane; IEA:UniProtKB-SubCell.::GO:0030141; C:secretory granule; IDA:RGD.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0019904; F:protein domain specific binding; NAS:RGD.
GO:0008333; P:endosome to lysosome transport; IMP:RGD.::GO:0006886; P:intracellular protein transport; IEA:InterPro.
79Q99LI8    775   HGS_MOUSE Hepatocyte growth factor-regulated ...1380.00000002     60.1     22     52GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell.::GO:0032585; C:multivesicular body membrane; IEA:UniProtKB-SubCell.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0006886; P:intracellular protein transport; IEA:InterPro.
80O42287    1270   ITSN1_XENLA Intersectin-1 OS=Xenopus laevis (...510.041     40     39     49GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0012505; C:endomembrane system; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-KW.::GO:0045202; C:synapse; IEA:UniProtKB-KW.::GO:0019717; C:synaptosome; IEA:UniProtKB-SubCell.
GO:0005509; F:calcium ion binding; IEA:InterPro.
GO:0006897; P:endocytosis; IEA:UniProtKB-KW.
81Q5ZJJ9    202   OSTF1_CHICK Osteoclast-stimulating factor 1 O...970.00000002     57.4     30     49GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
82O12940    515   TOM1_CHICK Target of Myb protein 1 OS=Gallus ...1310.00000002     59.7     22     56GO:0005829; C:cytosol; ISS:AgBase.::GO:0005769; C:early endosome; ISS:AgBase.::GO:0016020; C:membrane; ISS:AgBase.
GO:0006886; P:intracellular protein transport; IEA:InterPro.
83O14964    777   HGS_HUMAN Hepatocyte growth factor-regulated ...1380.00000003     60.1     22     52GO:0005829; C:cytosol; TAS:Reactome.::GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell.::GO:0032585; C:multivesicular body membrane; IEA:UniProtKB-SubCell.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0019904; F:protein domain specific binding; IPI:UniProtKB.
GO:0016044; P:cellular membrane organization; TAS:Reactome.::GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.::GO:0006886; P:intracellular protein transport; IEA:InterPro.::GO:0008285; P:negative regulation of cell proliferation; TAS:ProtInc.::GO:0042059; P:negative regulation of epidermal growth factor receptor signaling pathway; TAS:Reactome.::GO:0046426; P:negative regulation of JAK-STAT cascade; IDA:HGNC.::GO:0042176; P:regulation of protein catabolic process; TAS:HGNC.
84O35413    1196   SRBS2_RAT Sorbin and SH3 domain-containing pr...520.004     43.5     40     54GO:0043025; C:neuronal cell body; IDA:RGD.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.::GO:0014069; C:postsynaptic density; IDA:RGD.
GO:0008270; F:zinc ion binding; IEA:InterPro.
85P32793    468   YSC84_YEAST Protein YSC84 OS=Saccharomyces ce...790.00000003     59.3     38     53GO:0030479; C:actin cortical patch; IDA:SGD.
GO:0051015; F:actin filament binding; IDA:SGD.
GO:0051666; P:actin cortical patch localization; IMP:SGD.::GO:0051017; P:actin filament bundle assembly; IDA:SGD.::GO:0006897; P:endocytosis; IGI:SGD.
86Q3UTJ2    1180   SRBS2_MOUSE Sorbin and SH3 domain-containing ...520.004     43.5     40     54GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.::GO:0030018; C:Z disc; IEA:UniProtKB-SubCell.
GO:0008270; F:zinc ion binding; IEA:InterPro.
87B0BNA1    340   SH3Y1_RAT SH3 domain-containing YSC84-like pr...530.00000004     58.5     49     62
88O88746    492   TOM1_MOUSE Target of Myb protein 1 OS=Mus mus...1310.00000004     58.9     21     56GO:0005829; C:cytosol; ISS:UniProtKB.::GO:0005769; C:early endosome; ISS:UniProtKB.::GO:0016020; C:membrane; ISS:UniProtKB.
GO:0005515; F:protein binding; IPI:IntAct.
GO:0006886; P:intracellular protein transport; IEA:InterPro.
89P53281    241   LSB1_YEAST LAS seventeen-binding protein 1 OS...520.00000004     57.4     46     62GO:0030479; C:actin cortical patch; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IDA:SGD.
GO:0005515; F:protein binding; IPI:IntAct.
90O94875    1100   SRBS2_HUMAN Sorbin and SH3 domain-containing ...520.002     44.3     42     54GO:0015629; C:actin cytoskeleton; TAS:ProtInc.::GO:0005622; C:intracellular; IEA:InterPro.::GO:0005634; C:nucleus; NAS:UniProtKB.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.::GO:0030018; C:Z disc; NAS:UniProtKB.
GO:0008093; F:cytoskeletal adaptor activity; TAS:ProtInc.::GO:0005200; F:structural constituent of cytoskeleton; TAS:ProtInc.::GO:0008307; F:structural constituent of muscle; TAS:ProtInc.::GO:0008270; F:zinc ion binding; IEA:InterPro.
91O08641    340   SH3Y1_MOUSE SH3 domain-containing YSC84-like ...530.00000005     58.2     49     62
GO:0005515; F:protein binding; IPI:IntAct.
records
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