Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YHL002W
Length:
452
Number of sequences:
5887
Description:
YHL002W HSE1 SGDID:S000000994, Chr VIII from 102612-103970, Genome Release 64-1-1, Verified ORF, "Subunit of the endosomal Vps27p-Hse1p complex required for sorting of ubiquitinated membrane proteins into intralumenal vesicles prior to vacuolar degradation, as well as for recycling of Golgi proteins and formation of lumenal membranes"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
571A1C4A5    1253   MYO1_ASPCL Myosin-1 OS=3887 / NRRL 1). GN=myo...311.9     34.7     32     65GO:0030479; C:actin cortical patch; IEA:UniProtKB-SubCell.::GO:0016459; C:myosin complex; IEA:UniProtKB-KW.
GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003774; F:motor activity; IEA:InterPro.
572Q9JLB2    675   MPP5_MOUSE MAGUK p55 subfamily member 5 OS=Mu...891.9     34.7     29     48GO:0012505; C:endomembrane system; IEA:UniProtKB-SubCell.::GO:0043219; C:lateral loop; IDA:BHF-UCL.::GO:0035749; C:myelin sheath adaxonal region; IDA:BHF-UCL.::GO:0043220; C:Schmidt-Lanterman incisure; IDA:BHF-UCL.::GO:0005923; C:tight junction; IEA:UniProtKB-SubCell.
GO:0032287; P:peripheral nervous system myelin maintenance; IMP:BHF-UCL.::GO:0035750; P:protein localization to myelin sheath abaxonal region; IMP:BHF-UCL.
573Q12774    1597   ARHG5_HUMAN Rho guanine nucleotide exchange f...722.1     34.7     33     46GO:0005737; C:cytoplasm; IDA:HPA.::GO:0005886; C:plasma membrane; IDA:HPA.
GO:0005525; F:GTP binding; TAS:ProtInc.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro.
GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro.
574C5DE38    342   SHO1_LACTC High osmolarity signaling protein ...592.1     34.3     39     56GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0006950; P:response to stress; IEA:UniProtKB-KW.
575A7TI28    358   SHO1_VANPO High osmolarity signaling protein ...552.3     34.3     40     56GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0006950; P:response to stress; IEA:UniProtKB-KW.
576P40996    536   SCD2_SCHPO Protein scd2/ral3 OS=Schizosacchar...632.3     34.3     32     46GO:0071521; C:Cdc42 GTPase complex; TAS:PomBase.::GO:0032153; C:cell division site; IDA:PomBase.::GO:0051286; C:cell tip; IDA:PomBase.::GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.
GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0032488; P:Cdc42 protein signal transduction; TAS:PomBase.::GO:0031137; P:regulation of conjugation with cellular fusion; IMP:PomBase.::GO:0032878; P:regulation of establishment or maintenance of cell polarity; IMP:PomBase.
577Q62915    909   CSKP_RAT Peripheral plasma membrane protein C...752.5     34.3     28     45GO:0060170; C:cilium membrane; IDA:BHF-UCL.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0030425; C:dendrite; IDA:RGD.::GO:0005624; C:membrane fraction; IDA:RGD.::GO:0005634; C:nucleus; IDA:BHF-UCL.::GO:0042734; C:presynaptic membrane; IDA:BHF-UCL.::GO:0043234; C:protein complex; IDA:RGD.::GO:0005625; C:soluble fraction; IDA:RGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; TAS:RGD.::GO:0004683; F:calmodulin-dependent protein kinase activity; TAS:RGD.::GO:0030165; F:PDZ domain binding; IPI:RGD.::GO:0008022; F:protein C-terminus binding; IMP:RGD.::GO:0032403; F:protein complex binding; IPI:RGD.::GO:0003713; F:transcription coactivator activity; TAS:RGD.
GO:0006886; P:intracellular protein transport; IMP:RGD.::GO:0006461; P:protein complex assembly; TAS:RGD.
578Q13625    1128   ASPP2_HUMAN Apoptosis-stimulating of p53 prot...662.5     34.3     27     47GO:0005634; C:nucleus; IDA:UniProtKB.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.
GO:0051059; F:NF-kappaB binding; IPI:UniProtKB.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0017124; F:SH3 domain binding; IEA:UniProtKB-KW.::GO:0005070; F:SH3/SH2 adaptor activity; TAS:ProtInc.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0006917; P:induction of apoptosis; IDA:UniProtKB.::GO:0045786; P:negative regulation of cell cycle; TAS:UniProtKB.::GO:0007165; P:signal transduction; TAS:ProtInc.
579P42679    507   MATK_HUMAN Megakaryocyte-associated tyrosine-...272.6     34.3     52     67GO:0005737; C:cytoplasm; IDA:HPA.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IDA:HPA.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC.::GO:0004713; F:protein tyrosine kinase activity; IEA:UniProtKB-KW.
GO:0008283; P:cell proliferation; TAS:ProtInc.::GO:0007498; P:mesoderm development; TAS:ProtInc.::GO:0008284; P:positive regulation of cell proliferation; TAS:ProtInc.
580Q17QN6    466   EM55_BOVIN 55 kDa erythrocyte membrane protei...1122.6     34.3     25     43GO:0016020; C:membrane; IEA:UniProtKB-SubCell.::GO:0032420; C:stereocilium; IEA:UniProtKB-SubCell.
GO:0090022; P:regulation of neutrophil chemotaxis; ISS:UniProtKB.
581B2RQE8    841   RHG42_MOUSE Rho GTPase-activating protein 42 ...542.7     34.3     33     46GO:0005622; C:intracellular; IEA:InterPro.
GO:0008093; F:cytoskeletal adaptor activity; IEA:InterPro.::GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0017124; F:SH3 domain binding; IEA:InterPro.
GO:0046847; P:filopodium assembly; IEA:InterPro.::GO:0007165; P:signal transduction; IEA:InterPro.
582E5AD87    336   SHO1_LEPMJ High osmolarity signaling protein ...782.7     33.9     33     46GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0006950; P:response to stress; IEA:UniProtKB-KW.
583Q5U2Y3    576   MPP7_RAT MAGUK p55 subfamily member 7 OS=Ratt...672.9     33.9     28     48GO:0005923; C:tight junction; IEA:UniProtKB-SubCell.
584D8PSG0    331   SHO1_SCHCM High osmolarity signaling protein ...533     33.9     34     58GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0006950; P:response to stress; IEA:UniProtKB-KW.
585Q7Z8J6    1282   MYO1_USTMA Myosin-1 OS=Ustilago maydis (strai...603     34.3     33     47GO:0030479; C:actin cortical patch; IEA:UniProtKB-SubCell.::GO:0016459; C:myosin complex; IEA:UniProtKB-KW.
GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003774; F:motor activity; IEA:InterPro.
586Q00013    466   EM55_HUMAN 55 kDa erythrocyte membrane protei...1123     33.9     24     42GO:0005887; C:integral to plasma membrane; TAS:ProtInc.::GO:0005624; C:membrane fraction; TAS:ProtInc.::GO:0032420; C:stereocilium; IEA:UniProtKB-SubCell.
GO:0004385; F:guanylate kinase activity; TAS:ProtInc.::GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0090022; P:regulation of neutrophil chemotaxis; ISS:UniProtKB.::GO:0007165; P:signal transduction; TAS:ProtInc.
587A9CB74    466   EM55_PAPAN 55 kDa erythrocyte membrane protei...1213.2     33.9     24     41GO:0016020; C:membrane; IEA:UniProtKB-SubCell.::GO:0032420; C:stereocilium; IEA:UniProtKB-SubCell.
GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
GO:0090022; P:regulation of neutrophil chemotaxis; ISS:UniProtKB.
588A6QQZ7    576   MPP7_BOVIN MAGUK p55 subfamily member 7 OS=Bo...573.2     33.9     30     49GO:0005923; C:tight junction; IEA:UniProtKB-SubCell.
589Q5T0N5    605   FBP1L_HUMAN Formin-binding protein 1-like OS=...833.3     33.9     24     45GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell.::GO:0016023; C:cytoplasmic membrane-bounded vesicle; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0008289; F:lipid binding; IEA:UniProtKB-KW.
GO:0006897; P:endocytosis; IEA:UniProtKB-KW.
590Q5RDW4    466   EM55_PONAB 55 kDa erythrocyte membrane protei...1123.3     33.9     24     42GO:0016020; C:membrane; IEA:UniProtKB-SubCell.::GO:0032420; C:stereocilium; IEA:UniProtKB-SubCell.
GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
GO:0090022; P:regulation of neutrophil chemotaxis; ISS:UniProtKB.
591Q92968    403   PEX13_HUMAN Peroxisomal membrane protein PEX1...543.7     33.5     39     52GO:0005779; C:integral to peroxisomal membrane; IDA:UniProtKB.::GO:0005624; C:membrane fraction; IDA:UniProtKB.
GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0021795; P:cerebral cortex cell migration; ISS:UniProtKB.::GO:0001561; P:fatty acid alpha-oxidation; ISS:UniProtKB.::GO:0007626; P:locomotory behavior; ISS:UniProtKB.::GO:0060152; P:microtubule-based peroxisome localization; ISS:UniProtKB.::GO:0001764; P:neuron migration; ISS:UniProtKB.::GO:0016560; P:protein import into peroxisome matrix, docking; IMP:UniProtKB.::GO:0001967; P:suckling behavior; ISS:UniProtKB.
592A1CEK1    714   VPS27_ASPCL Vacuolar protein sorting-associat...544     33.5     26     59GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0006886; P:intracellular protein transport; IEA:InterPro.
593Q2HWF0    605   FBP1L_RAT Formin-binding protein 1-like OS=Ra...834     33.5     24     43GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell.::GO:0016023; C:cytoplasmic membrane-bounded vesicle; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0008289; F:lipid binding; IEA:UniProtKB-KW.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0006897; P:endocytosis; IEA:UniProtKB-KW.::GO:0007399; P:nervous system development; IEA:UniProtKB-KW.
594Q751J2    330   SHO1_ASHGO High osmolarity signaling protein ...594.2     33.1     36     56GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0006950; P:response to stress; IEA:UniProtKB-KW.
595Q6A065    1588   CE170_MOUSE Centrosomal protein of 170 kDa OS...654.2     33.9     32     49GO:0005814; C:centriole; IEA:UniProtKB-SubCell.::GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0005819; C:spindle; IEA:UniProtKB-SubCell.
596Q7SDM3    1235   MYO1_NEUCR Myosin-1 OS=1257 / FGSC 987). GN=m...504.2     33.5     28     44GO:0030479; C:actin cortical patch; IEA:UniProtKB-SubCell.::GO:0016459; C:myosin complex; IEA:UniProtKB-KW.
GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003774; F:motor activity; IEA:InterPro.
597Q06336    557   GGA1_YEAST ADP-ribosylation factor-binding pr...614.3     33.5     33     46GO:0030131; C:clathrin adaptor complex; IEA:InterPro.::GO:0044431; C:Golgi apparatus part; IEA:InterPro.::GO:0005802; C:trans-Golgi network; IDA:SGD.
GO:0043130; F:ubiquitin binding; IDA:SGD.
GO:0006895; P:Golgi to endosome transport; IMP:SGD.::GO:0006896; P:Golgi to vacuole transport; IPI:SGD.::GO:0043328; P:protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway; IMP:SGD.
598Q62662    506   FRK_RAT Tyrosine-protein kinase FRK OS=Rattus...584.7     33.5     34     45GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IDA:RGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC.
GO:0030154; P:cell differentiation; IEP:RGD.
599Q9D0K1    405   PEX13_MOUSE Peroxisomal membrane protein PEX1...554.8     33.1     38     51
GO:0000268; F:peroxisome targeting sequence binding; TAS:MGI.
GO:0021795; P:cerebral cortex cell migration; IMP:MGI.::GO:0001561; P:fatty acid alpha-oxidation; IMP:MGI.::GO:0007626; P:locomotory behavior; IMP:MGI.::GO:0060152; P:microtubule-based peroxisome localization; IMP:MGI.::GO:0001764; P:neuron migration; IMP:MGI.::GO:0016560; P:protein import into peroxisome matrix, docking; IMP:MGI.::GO:0001967; P:suckling behavior; IMP:MGI.
600Q0P5B1    403   PEX13_BOVIN Peroxisomal membrane protein PEX1...554.9     33.1     38     51GO:0005779; C:integral to peroxisomal membrane; ISS:UniProtKB.::GO:0005624; C:membrane fraction; ISS:UniProtKB.
GO:0016560; P:protein import into peroxisome matrix, docking; ISS:UniProtKB.
601P10447    439   ABL_FSVHY Tyrosine-protein kinase transformin...525     33.1     33     52
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC.
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