Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YHL002W
Length:
452
Number of sequences:
5887
Description:
YHL002W HSE1 SGDID:S000000994, Chr VIII from 102612-103970, Genome Release 64-1-1, Verified ORF, "Subunit of the endosomal Vps27p-Hse1p complex required for sorting of ubiquitinated membrane proteins into intralumenal vesicles prior to vacuolar degradation, as well as for recycling of Golgi proteins and formation of lumenal membranes"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
1P38753    452   HSE1_YEAST Class E vacuolar protein-sorting m...4520     934     100     100GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.::GO:0033565; C:ESCRT-0 complex; IPI:SGD.
GO:0043130; F:ubiquitin binding; IDA:SGD.
GO:0045324; P:late endosome to vacuole transport; IMP:SGD.::GO:0006623; P:protein targeting to vacuole; IMP:SGD.
2Q6FN49    450   HSE1_CANGA Class E vacuolar protein-sorting m...4601e-143     425     51     66GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.
GO:0006886; P:intracellular protein transport; IEA:InterPro.
3Q6CVA8    508   HSE1_KLULA Class E vacuolar protein-sorting m...4062e-127     386     52     72GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.
GO:0006886; P:intracellular protein transport; IEA:InterPro.
4Q75DS3    443   HSE1_ASHGO Class E vacuolar protein-sorting m...4374e-127     382     46     66GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.
GO:0006886; P:intracellular protein transport; IEA:InterPro.
5Q6C2N2    685   HSE1_YARLI Class E vacuolar protein-sorting m...3972e-88     290     40     57GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.
GO:0006886; P:intracellular protein transport; IEA:InterPro.
6Q5A895    498   HSE1_CANAL Class E vacuolar protein-sorting m...3742e-86     279     42     64GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.
GO:0006886; P:intracellular protein transport; IEA:InterPro.
7Q6BNP6    512   HSE1_DEBHA Class E vacuolar protein-sorting m...4323e-85     277     39     58GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.
GO:0006886; P:intracellular protein transport; IEA:InterPro.
8A3LXQ8    475   HSE1_PICST Class E vacuolar protein-sorting m...4132e-82     268     38     63GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.
GO:0006886; P:intracellular protein transport; IEA:InterPro.
9Q1E878    612   HSE1_COCIM Class E vacuolar protein-sorting m...4441e-79     265     37     55GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.
GO:0006886; P:intracellular protein transport; IEA:InterPro.
10Q5BBL4    581   HSE1_EMENI Class E vacuolar protein-sorting m...3657e-75     251     37     58GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.
GO:0006886; P:intracellular protein transport; IEA:InterPro.
11Q0U6X7    618   HSE1_PHANO Class E vacuolar protein-sorting m...3662e-74     251     37     58GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.
GO:0006886; P:intracellular protein transport; IEA:InterPro.
12A1DFN5    603   HSE1_NEOFI Class E vacuolar protein-sorting m...4515e-74     249     35     53GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.
GO:0006886; P:intracellular protein transport; IEA:InterPro.
13A2QW93    611   HSE1_ASPNC Class E vacuolar protein-sorting m...4433e-73     248     35     53GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.
GO:0006886; P:intracellular protein transport; IEA:InterPro.
14A1CEK6    599   HSE1_ASPCL Class E vacuolar protein-sorting m...3751e-71     243     37     57GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.
GO:0006886; P:intracellular protein transport; IEA:InterPro.
15Q0CJU8    597   HSE1_ASPTN Class E vacuolar protein-sorting m...4427e-71     241     34     51GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.
GO:0006886; P:intracellular protein transport; IEA:InterPro.
16Q7S6J4    745   HSE1_NEUCR Class E vacuolar protein-sorting m...4345e-69     239     35     53GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.
GO:0006886; P:intracellular protein transport; IEA:InterPro.
17A4RF61    718   HSE1_MAGO7 Class E vacuolar protein-sorting m...4413e-68     236     34     53GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.
GO:0006886; P:intracellular protein transport; IEA:InterPro.
18Q4WHP5    584   HSE1_ASPFU Class E vacuolar protein-sorting m...4518e-68     233     35     51GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.
GO:0006886; P:intracellular protein transport; IEA:InterPro.
19Q2GT05    713   HSE1_CHAGB Class E vacuolar protein-sorting m...3153e-65     228     39     60GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.
GO:0006886; P:intracellular protein transport; IEA:InterPro.
20O74749    373   HSE1_SCHPO Class E vacuolar protein-sorting m...3672e-63     215     35     56GO:0005829; C:cytosol; IDA:PomBase.::GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.::GO:0033565; C:ESCRT-0 complex; IPI:PomBase.::GO:0005794; C:Golgi apparatus; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.
GO:0031321; P:ascospore-type prospore assembly; IGI:PomBase.::GO:0033554; P:cellular response to stress; IEP:PomBase.::GO:0006900; P:membrane budding; IC:PomBase.::GO:0043328; P:protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway; IMP:PomBase.
21Q4P5J4    593   HSE1_USTMA Class E vacuolar protein-sorting m...4032e-54     196     30     51GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.
GO:0006886; P:intracellular protein transport; IEA:InterPro.
22P0CR78    660   HSE1_CRYNJ Class E vacuolar protein-sorting m...4084e-47     176     29     49GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.
GO:0006886; P:intracellular protein transport; IEA:InterPro.
23O93436    468   STAM2_CHICK Signal transducing adapter molecu...2632e-29     122     28     50GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell.
GO:0006886; P:intracellular protein transport; IEA:InterPro.
24O75886    525   STAM2_HUMAN Signal transducing adapter molecu...2644e-28     120     28     51GO:0005829; C:cytosol; TAS:Reactome.::GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IDA:HPA.
GO:0005515; F:protein binding; IPI:IntAct.
GO:0016044; P:cellular membrane organization; TAS:Reactome.::GO:0016197; P:endosome transport; TAS:Reactome.::GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.::GO:0006886; P:intracellular protein transport; IEA:InterPro.::GO:0042059; P:negative regulation of epidermal growth factor receptor signaling pathway; TAS:Reactome.
25Q5XHY7    523   STAM2_RAT Signal transducing adapter molecule...2631e-26     115     28     51GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell.
GO:0006886; P:intracellular protein transport; IEA:InterPro.
26O88811    523   STAM2_MOUSE Signal transducing adapter molecu...2682e-26     114     27     49GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell.
GO:0006886; P:intracellular protein transport; IEA:InterPro.
27Q92783    540   STAM1_HUMAN Signal transducing adapter molecu...3033e-26     114     26     48GO:0005829; C:cytosol; TAS:Reactome.::GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell.
GO:0005070; F:SH3/SH2 adaptor activity; TAS:ProtInc.
GO:0016044; P:cellular membrane organization; TAS:Reactome.::GO:0016197; P:endosome transport; TAS:Reactome.::GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.::GO:0006886; P:intracellular protein transport; IEA:InterPro.::GO:0042059; P:negative regulation of epidermal growth factor receptor signaling pathway; TAS:Reactome.
28P70297    548   STAM1_MOUSE Signal transducing adapter molecu...4631e-25     113     26     44GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell.
GO:0005515; F:protein binding; IPI:MGI.
GO:0006886; P:intracellular protein transport; IEA:InterPro.
29O01498    457   STAM1_CAEEL Signal transducing adapter molecu...3232e-23     105     29     46GO:0044441; C:cilium part; IDA:UniProtKB.::GO:0005769; C:early endosome; IDA:WormBase.::GO:0033565; C:ESCRT-0 complex; IPI:WormBase.
GO:0008022; F:protein C-terminus binding; IPI:WormBase.::GO:0043130; F:ubiquitin binding; IDA:WormBase.
GO:0008333; P:endosome to lysosome transport; IMP:WormBase.::GO:0048013; P:ephrin receptor signaling pathway; IGI:UniProtKB.::GO:0006886; P:intracellular protein transport; IEA:InterPro.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0043409; P:negative regulation of MAPK cascade; IMP:UniProtKB.
30P0CR79    660   HSE1_CRYNB Class E vacuolar protein-sorting m...1483e-22     103     33     57GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.
GO:0006886; P:intracellular protein transport; IEA:InterPro.
31Q07883    217   GRB2_CHICK Growth factor receptor-bound prote...490.0001     46.6     43     61GO:0005768; C:endosome; ISS:UniProtKB.::GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; ISS:UniProtKB.
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