Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YGR281W
Length:
1477
Number of sequences:
5887
Description:
YGR281W YOR1 SGDID:S000003513, Chr VII from 1052824-1057257, Genome Release 64-1-1, Verified ORF, "Plasma membrane ATP-binding cassette (ABC) transporter, multidrug transporter mediates export of many different organic anions including oligomycin; similar to human cystic fibrosis transmembrane receptor (CFTR)"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
1P53049    1477   YOR1_YEAST Oligomycin resistance ATP-dependen...14770     3051     100     100GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005624; C:membrane fraction; IDA:SGD.::GO:0005886; C:plasma membrane; IDA:SGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008559; F:xenobiotic-transporting ATPase activity; TAS:SGD.
2O15439    1325   MRP4_HUMAN Multidrug resistance-associated pr...13870     695     32     51GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005624; C:membrane fraction; IDA:MGI.::GO:0005886; C:plasma membrane; IDA:MGI.::GO:0031088; C:platelet dense granule membrane; IDA:MGI.
GO:0016404; F:15-hydroxyprostaglandin dehydrogenase (NAD+) activity; NAS:UniProtKB.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0042626; F:ATPase activity, coupled to transmembrane movement of substances; IEA:InterPro.::GO:0005254; F:chloride channel activity; IEA:InterPro.
GO:0030168; P:platelet activation; TAS:Reactome.::GO:0002576; P:platelet degranulation; TAS:Reactome.
3Q5F364    1525   MRP1_CHICK Multidrug resistance-associated pr...14260     697     31     51GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0042626; F:ATPase activity, coupled to transmembrane movement of substances; IEA:InterPro.
4Q864R9    1531   MRP1_MACFA Multidrug resistance-associated pr...14340     694     31     51GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0042626; F:ATPase activity, coupled to transmembrane movement of substances; IEA:InterPro.
5P33527    1531   MRP1_HUMAN Multidrug resistance-associated pr...14280     691     31     51GO:0005794; C:Golgi apparatus; IDA:HPA.::GO:0005887; C:integral to plasma membrane; TAS:ProtInc.::GO:0005624; C:membrane fraction; TAS:ProtInc.::GO:0005634; C:nucleus; IDA:HPA.
GO:0005524; F:ATP binding; TAS:ProtInc.::GO:0042626; F:ATPase activity, coupled to transmembrane movement of substances; TAS:ProtInc.
GO:0019370; P:leukotriene biosynthetic process; TAS:Reactome.::GO:0006692; P:prostanoid metabolic process; TAS:Reactome.::GO:0042493; P:response to drug; TAS:ProtInc.
6Q6UR05    1531   MRP1_CANFA Multidrug resistance-associated pr...14320     689     31     52GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0042626; F:ATPase activity, coupled to transmembrane movement of substances; IEA:InterPro.
7Q8HXQ5    1530   MRP1_BOVIN Multidrug resistance-associated pr...14340     687     31     51GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0042626; F:ATPase activity, coupled to transmembrane movement of substances; IEA:InterPro.
8Q54JR2    1412   ABCC3_DICDI ABC transporter C family member 3...13050     683     34     52GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0042626; F:ATPase activity, coupled to transmembrane movement of substances; ISS:dictyBase.
9O35379    1528   MRP1_MOUSE Multidrug resistance-associated pr...14280     669     30     50GO:0005887; C:integral to plasma membrane; IDA:MGI.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0042626; F:ATPase activity, coupled to transmembrane movement of substances; IEA:InterPro.
10Q8CG09    1532   MRP1_RAT Multidrug resistance-associated prot...14540     667     30     50GO:0016323; C:basolateral plasma membrane; IDA:RGD.::GO:0005737; C:cytoplasm; IDA:RGD.::GO:0005887; C:integral to plasma membrane; IDA:RGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0015562; F:efflux transmembrane transporter activity; IDA:RGD.::GO:0015431; F:glutathione S-conjugate-exporting ATPase activity; IMP:RGD.::GO:0034634; F:glutathione transmembrane transporter activity; IMP:RGD.::GO:0034040; F:lipid-transporting ATPase activity; IDA:RGD.::GO:0005324; F:long-chain fatty acid transporter activity; IDA:RGD.::GO:0016491; F:oxidoreductase activity; IEA:InterPro.::GO:0046624; F:sphingolipid transporter activity; IMP:RGD.::GO:0008559; F:xenobiotic-transporting ATPase activity; IDA:RGD.
GO:0060326; P:cell chemotaxis; IMP:RGD.::GO:0043215; P:daunorubicin transport; IMP:RGD.::GO:0046618; P:drug export; IDA:RGD.::GO:0043526; P:neuroprotection; IMP:RGD.::GO:0033700; P:phospholipid efflux; IMP:RGD.::GO:0015911; P:plasma membrane long-chain fatty acid transport; IDA:RGD.::GO:0030335; P:positive regulation of cell migration; IMP:RGD.::GO:0006979; P:response to oxidative stress; IMP:RGD.
11Q42093    1623   AB2C_ARATH ABC transporter C family member 2 ...14050     667     32     51GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0000325; C:plant-type vacuole; IDA:TAIR.::GO:0005774; C:vacuolar membrane; IDA:TAIR.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0008559; F:xenobiotic-transporting ATPase activity; IEA:EC.
12Q54U44    1323   ABCCC_DICDI ABC transporter C family member 1...13800     658     33     50GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0042626; F:ATPase activity, coupled to transmembrane movement of substances; ISS:dictyBase.
13O15438    1527   MRP3_HUMAN Canalicular multispecific organic ...14320     663     31     50GO:0005887; C:integral to plasma membrane; TAS:ProtInc.::GO:0005624; C:membrane fraction; TAS:ProtInc.
GO:0005524; F:ATP binding; TAS:ProtInc.::GO:0042626; F:ATPase activity, coupled to transmembrane movement of substances; TAS:ProtInc.::GO:0008514; F:organic anion transmembrane transporter activity; TAS:ProtInc.
GO:0015721; P:bile acid and bile salt transport; TAS:Reactome.::GO:0008206; P:bile acid metabolic process; TAS:Reactome.
14Q9R1X5    1436   MRP5_MOUSE Multidrug resistance-associated pr...14010     654     32     50GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0042626; F:ATPase activity, coupled to transmembrane movement of substances; IEA:InterPro.
15Q9QYM0    1436   MRP5_RAT Multidrug resistance-associated prot...11970     651     34     52GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0048471; C:perinuclear region of cytoplasm; IDA:RGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0042626; F:ATPase activity, coupled to transmembrane movement of substances; IEA:InterPro.
GO:0032868; P:response to insulin stimulus; IEP:RGD.::GO:0032496; P:response to lipopolysaccharide; IEP:RGD.
16Q8ST87    1334   ABCCA_DICDI ABC transporter C family member 1...13790     645     32     50GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0042626; F:ATPase activity, coupled to transmembrane movement of substances; ISS:dictyBase.
17Q9C8G9    1622   AB1C_ARATH ABC transporter C family member 1 ...13960     649     31     50GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0000325; C:plant-type vacuole; IDA:TAIR.::GO:0009506; C:plasmodesma; IDA:TAIR.::GO:0005774; C:vacuolar membrane; IDA:TAIR.
GO:0015446; F:arsenite-transmembrane transporting ATPase activity; IDA:TAIR.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0071992; F:phytochelatin transmembrane transporter activity; IDA:TAIR.::GO:0008559; F:xenobiotic-transporting ATPase activity; IEA:EC.
GO:0046685; P:response to arsenic-containing substance; IMP:TAIR.
18O15440    1437   MRP5_HUMAN Multidrug resistance-associated pr...12010     643     34     52GO:0005887; C:integral to plasma membrane; TAS:ProtInc.::GO:0005624; C:membrane fraction; IDA:MGI.
GO:0005524; F:ATP binding; TAS:ProtInc.::GO:0042626; F:ATPase activity, coupled to transmembrane movement of substances; IEA:InterPro.::GO:0008514; F:organic anion transmembrane transporter activity; TAS:ProtInc.
19B2RX12    1523   MRP3_MOUSE Canalicular multispecific organic ...14130     643     30     49GO:0005887; C:integral to plasma membrane; IDA:MGI.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0042626; F:ATPase activity, coupled to transmembrane movement of substances; IEA:InterPro.
20Q80WJ6    1366   MRP9_MOUSE Multidrug resistance-associated pr...13990     634     32     50GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005739; C:mitochondrion; IDA:MGI.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0042626; F:ATPase activity, coupled to transmembrane movement of substances; IEA:InterPro.
21Q63120    1541   MRP2_RAT Canalicular multispecific organic an...14540     637     30     49GO:0016324; C:apical plasma membrane; IDA:UniProtKB.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0042626; F:ATPase activity, coupled to transmembrane movement of substances; IEA:InterPro.::GO:0008514; F:organic anion transmembrane transporter activity; TAS:RGD.::GO:0019904; F:protein domain specific binding; IPI:RGD.
GO:0030644; P:cellular chloride ion homeostasis; IDA:RGD.::GO:0006855; P:drug transmembrane transport; IMP:RGD.::GO:0015732; P:prostaglandin transport; IMP:RGD.::GO:0046685; P:response to arsenic-containing substance; IEP:RGD.::GO:0009408; P:response to heat; IEP:RGD.::GO:0031427; P:response to methotrexate; IEP:RGD.::GO:0006979; P:response to oxidative stress; IEP:RGD.::GO:0070327; P:thyroid hormone transport; IMP:RGD.
22Q92887    1545   MRP2_HUMAN Canalicular multispecific organic ...14340     637     30     49GO:0016324; C:apical plasma membrane; ISS:UniProtKB.::GO:0005887; C:integral to plasma membrane; TAS:ProtInc.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0042626; F:ATPase activity, coupled to transmembrane movement of substances; TAS:ProtInc.::GO:0008514; F:organic anion transmembrane transporter activity; TAS:ProtInc.::GO:0005515; F:protein binding; IPI:IntAct.
23Q6Y306    1366   MRP9_RAT Multidrug resistance-associated prot...14100     630     31     50GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0042626; F:ATPase activity, coupled to transmembrane movement of substances; IEA:InterPro.
24O88563    1522   MRP3_RAT Canalicular multispecific organic an...14130     631     30     49GO:0016323; C:basolateral plasma membrane; IDA:RGD.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0015432; F:bile acid-exporting ATPase activity; IMP:RGD.::GO:0008559; F:xenobiotic-transporting ATPase activity; IMP:RGD.
GO:0015722; P:canalicular bile acid transport; IDA:MGI.::GO:0032355; P:response to estradiol stimulus; IEP:RGD.::GO:0032496; P:response to lipopolysaccharide; IEP:RGD.::GO:0014070; P:response to organic cyclic compound; IEP:RGD.::GO:0010243; P:response to organic nitrogen; IEP:RGD.
25Q28689    1564   MRP2_RABIT Canalicular multispecific organic ...14490     630     30     48GO:0016324; C:apical plasma membrane; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0042626; F:ATPase activity, coupled to transmembrane movement of substances; IEA:InterPro.
26Q96J65    1359   MRP9_HUMAN Multidrug resistance-associated pr...13940     620     32     49GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0042626; F:ATPase activity, coupled to transmembrane movement of substances; IEA:InterPro.
27Q9C8H0    1495   AB12C_ARATH ABC transporter C family member 1...13820     614     32     50GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008559; F:xenobiotic-transporting ATPase activity; IEA:EC.
28Q10185    1478   ABC2_SCHPO ATP-binding cassette transporter a...14060     612     31     49GO:0000329; C:fungal-type vacuole membrane; IDA:PomBase.::GO:0005794; C:Golgi apparatus; IDA:PomBase.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0071997; F:glutathione S-conjugate-transporting ATPase activity; IMP:PomBase.::GO:0071992; F:phytochelatin transmembrane transporter activity; IMP:PomBase.
GO:0071276; P:cellular response to cadmium ion; IGI:PomBase.::GO:0071996; P:glutathione import into vacuole; IMP:PomBase.::GO:0071995; P:phytochelatin import into vacuole; IMP:PomBase.::GO:0009636; P:response to toxin; IEA:UniProtKB-KW.
29Q8VI47    1543   MRP2_MOUSE Canalicular multispecific organic ...14470     602     30     49GO:0016324; C:apical plasma membrane; IDA:MGI.::GO:0005887; C:integral to plasma membrane; IDA:MGI.::GO:0046581; C:intercellular canaliculus; IDA:MGI.::GO:0005624; C:membrane fraction; IDA:MGI.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0042626; F:ATPase activity, coupled to transmembrane movement of substances; IEA:InterPro.::GO:0005515; F:protein binding; IPI:MGI.
30Q96J66    1382   ABCCB_HUMAN ATP-binding cassette sub-family C...14030     595     31     48GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; TAS:Reactome.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0042626; F:ATPase activity, coupled to transmembrane movement of substances; IEA:InterPro.
31P14772    1559   BPT1_YEAST Bile pigment transporter 1 OS=Sacc...14211e-177     579     31     49GO:0000329; C:fungal-type vacuole membrane; IDA:SGD.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0042626; F:ATPase activity, coupled to transmembrane movement of substances; IEA:InterPro.::GO:0015127; F:bilirubin transmembrane transporter activity; IGI:SGD.::GO:0015086; F:cadmium ion transmembrane transporter activity; IDA:SGD.
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