UniProt_SwissProt BLAST: Single locus

Species:

Saccharomyces cerevisiae S288C

Locus:

YGR271W

Length:

1967

Number of sequences:

5887

Description:

YGR271W SLH1 SGDID:S000003503, Chr VII from 1031791-1037694, Genome Release 64-1-1, Verified ORF, "Putative RNA helicase related to Ski2p, involved in translation inhibition of non-poly(A) mRNAs; required for repressing propagation of dsRNA viruses"

rec.	Subject	Hit Length	Description	Align.Len	E value	Bit score	% ident.	% pos.	GO associations
151	Q6C024	575	PRP28_YARLI Pre-mRNA-splicing ATP-dependent R...	131	0.13	40.8	27	50	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003676; F:nucleic acid binding; IEA:InterPro.
									GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
152	Q8L4E9	501	RH36_ORYSJ DEAD-box ATP-dependent RNA helicas...	145	0.13	40.8	27	47
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
153	Q9Y7C4	578	ROK1_CANAL ATP-dependent RNA helicase CHR1 OS...	396	0.13	40.8	22	37	GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
									GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
154	Q6TV19	1865	DICER_DANRE Endoribonuclease Dicer OS=Danio r...	171	0.14	41.2	27	46	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016442; C:RNA-induced silencing complex; ISS:UniProtKB.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003725; F:double-stranded RNA binding; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0070883; F:pre-miRNA binding; IDA:ZFIN.::GO:0004525; F:ribonuclease III activity; IEA:InterPro.
									GO:0035279; P:mRNA cleavage involved in gene silencing by miRNA; IGI:ZFIN.::GO:0031054; P:pre-miRNA processing; ISS:UniProtKB.::GO:0030422; P:production of siRNA involved in RNA interference; ISS:UniProtKB.::GO:0030423; P:targeting of mRNA for destruction involved in RNA interference; ISS:UniProtKB.::GO:0021591; P:ventricular system development; IMP:ZFIN.
155	A5DAC8	534	DBP3_PICGU ATP-dependent RNA helicase DBP3 OS...	437	0.14	40.8	23	38	GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
									GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
156	A7TSV4	1012	MPH1_VANPO ATP-dependent DNA helicase MPH1 OS...	145	0.14	40.8	26	45	GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
									GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
157	Q6AYJ1	621	RECQ1_RAT ATP-dependent DNA helicase Q1 OS=Ra...	110	0.16	40.4	28	46	GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0043140; F:ATP-dependent 3'-5' DNA helicase activity; IEA:InterPro.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
									GO:0006310; P:DNA recombination; IEA:InterPro.::GO:0006281; P:DNA repair; IEA:InterPro.::GO:0006260; P:DNA replication; IEA:InterPro.
158	A7EFH4	1235	MPH1_SCLS1 ATP-dependent DNA helicase mph1 OS...	233	0.5	39.3	26	40	GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
									GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
159	Q55681	831	RECG_SYNY3 ATP-dependent DNA helicase recG OS...	91	0.17	40.4	25	51
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004003; F:ATP-dependent DNA helicase activity; IEA:InterPro.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
									GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
160	Q6FN65	565	ROK1_CANGA ATP-dependent RNA helicase ROK1 OS...	234	0.18	40.4	25	44	GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
									GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
161	Q9BYX4	1025	IFIH1_HUMAN Interferon-induced helicase C dom...	156	6.1	35.4	26	49	GO:0005829; C:cytosol; TAS:Reactome.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:InterPro.::GO:0003725; F:double-stranded RNA binding; IDA:UniProtKB.::GO:0004386; F:helicase activity; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0043021; F:ribonucleoprotein complex binding; IPI:UniProtKB.::GO:0003727; F:single-stranded RNA binding; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IDA:UniProtKB.
									GO:0039528; P:cytoplasmic pattern recognition receptor signaling pathway in response to virus; TAS:UniProtKB.::GO:0009597; P:detection of virus; TAS:BHF-UCL.::GO:0045087; P:innate immune response; TAS:UniProtKB.::GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW.::GO:0032480; P:negative regulation of type I interferon production; TAS:Reactome.::GO:0032727; P:positive regulation of interferon-alpha production; IMP:UniProtKB.::GO:0032728; P:positive regulation of interferon-beta production; IMP:UniProtKB.::GO:0016925; P:protein sumoylation; IDA:UniProtKB.::GO:0042981; P:regulation of apoptotic process; IEA:InterPro.::GO:0034344; P:regulation of type III interferon production; TAS:UniProtKB.
162	Q75AE1	569	ROK1_ASHGO ATP-dependent RNA helicase ROK1 OS...	195	0.19	40.4	27	48	GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
									GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
163	Q0CEI2	1377	DCL2_ASPTN Dicer-like protein 2 OS=Aspergillu...	153	0.29	40	27	44
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004525; F:ribonuclease III activity; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
									GO:0050688; P:regulation of defense response to virus; IEA:UniProtKB-KW.::GO:0009615; P:response to virus; IEA:UniProtKB-KW.::GO:0006396; P:RNA processing; IEA:InterPro.
164	A3GGE9	765	DBP4_PICST ATP-dependent RNA helicase DBP4 OS...	145	0.19	40.4	23	47	GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
									GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
165	Q8SQK9	489	DHH1_ENCCU ATP-dependent RNA helicase DHH1 OS...	96	0.2	40	34	48	GO:0000932; C:cytoplasmic mRNA processing body; IEA:UniProtKB-SubCell.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
									GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0051028; P:mRNA transport; IEA:UniProtKB-KW.::GO:0006417; P:regulation of translation; IEA:UniProtKB-KW.
166	P15424	664	MS116_YEAST ATP-dependent RNA helicase MSS116...	414	0.2	40.4	23	40	GO:0005759; C:mitochondrial matrix; IMP:SGD.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004004; F:ATP-dependent RNA helicase activity; IDA:SGD.::GO:0033592; F:RNA strand annealing activity; IDA:SGD.
									GO:0000372; P:Group I intron splicing; IMP:SGD.::GO:0000373; P:Group II intron splicing; IDA:SGD.::GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0006417; P:regulation of translation; IEA:UniProtKB-KW.::GO:0034337; P:RNA folding; IMP:SGD.
167	Q55750	1199	MFD_SYNY3 Transcription-repair-coupling facto...	80	0.21	40.4	31	46
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003684; F:damaged DNA binding; IEA:InterPro.
									GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
168	Q6CQX2	1002	MPH1_KLULA ATP-dependent DNA helicase MPH1 OS...	120	0.22	40.4	26	45	GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
									GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
169	A5DC85	586	DBP9_PICGU ATP-dependent RNA helicase DBP9 OS...	153	0.24	40	26	48	GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
									GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
170	Q8CSV3	682	RECG_STAES ATP-dependent DNA helicase recG OS...	91	0.24	40	29	49
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004003; F:ATP-dependent DNA helicase activity; IEA:InterPro.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
									GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
171	A6ZU15	564	ROK1_YEAS7 ATP-dependent RNA helicase ROK1 OS...	154	0.27	39.7	29	47	GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
									GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
172	P45818	564	ROK1_YEAST ATP-dependent RNA helicase ROK1 OS...	233	0.27	39.7	25	46	GO:0030686; C:90S preribosome; IDA:SGD.::GO:0005730; C:nucleolus; TAS:SGD.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004004; F:ATP-dependent RNA helicase activity; TAS:SGD.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
									GO:0006364; P:rRNA processing; TAS:SGD.::GO:0048254; P:snoRNA localization; IMP:SGD.
173	A4RHU9	1485	DCL2_MAGO7 Dicer-like protein 2 OS=blast fung...	123	0.28	40	31	49	GO:0005622; C:intracellular; IEA:InterPro.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003725; F:double-stranded RNA binding; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004525; F:ribonuclease III activity; IEA:InterPro.
									GO:0050688; P:regulation of defense response to virus; IEA:UniProtKB-KW.::GO:0009615; P:response to virus; IEA:UniProtKB-KW.::GO:0006396; P:RNA processing; IEA:InterPro.
174	Q4WRH5	739	ROK1_ASPFU ATP-dependent RNA helicase rok1 OS...	64	0.29	39.7	41	61	GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
									GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
175	Q6FQU5	507	DHH1_CANGA ATP-dependent RNA helicase DHH1 OS...	108	0.32	39.7	29	43	GO:0000932; C:cytoplasmic mRNA processing body; IEA:UniProtKB-SubCell.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
									GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0051028; P:mRNA transport; IEA:UniProtKB-KW.::GO:0006417; P:regulation of translation; IEA:UniProtKB-KW.
176	Q2UQW3	725	ROK1_ASPOR ATP-dependent RNA helicase rok1 OS...	81	0.33	39.7	33	59	GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
									GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
177	Q6FM43	582	PRP28_CANGA Pre-mRNA-splicing ATP-dependent R...	100	0.34	39.7	30	46	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003676; F:nucleic acid binding; IEA:InterPro.
									GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
178	Q99J87	678	DHX58_MOUSE Probable ATP-dependent RNA helica...	169	0.36	39.7	23	47	GO:0005737; C:cytoplasm; IDA:MGI.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:InterPro.::GO:0003725; F:double-stranded RNA binding; ISS:UniProtKB.::GO:0004386; F:helicase activity; IEA:UniProtKB-KW.::GO:0003727; F:single-stranded RNA binding; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; ISS:UniProtKB.
									GO:0051607; P:defense response to virus; IMP:UniProtKB.::GO:0045087; P:innate immune response; IEA:UniProtKB-KW.::GO:0045824; P:negative regulation of innate immune response; IMP:UniProtKB.::GO:0039534; P:negative regulation of MDA-5 signaling pathway; ISS:UniProtKB.::GO:0039536; P:negative regulation of RIG-I signaling pathway; IMP:UniProtKB.::GO:0032480; P:negative regulation of type I interferon production; IMP:UniProtKB.::GO:1900245; P:positive regulation of MDA-5 signaling pathway; IMP:UniProtKB.::GO:1900246; P:positive regulation of RIG-I signaling pathway; IMP:UniProtKB.::GO:0032481; P:positive regulation of type I interferon production; IMP:UniProtKB.
179	Q6BXG0	766	DBP4_DEBHA ATP-dependent RNA helicase DBP4 OS...	147	0.36	39.7	23	46	GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
									GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
180	O34942	682	RECG_BACSU ATP-dependent DNA helicase recG OS...	85	0.37	39.3	27	51
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004003; F:ATP-dependent DNA helicase activity; IEA:InterPro.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
									GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
181	A6QXC1	487	DBP3_AJECN ATP-dependent RNA helicase DBP3 OS...	99	1.6	37.4	28	47	GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
									GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.

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