Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YGR256W
Length:
492
Number of sequences:
5887
Description:
YGR256W GND2 SGDID:S000003488, Chr VII from 1004624-1006102, Genome Release 64-1-1, Verified ORF, "6-phosphogluconate dehydrogenase (decarboxylating), catalyzes an NADPH regenerating reaction in the pentose phosphate pathway; required for growth on D-glucono-delta-lactone"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
61P31937    336   3HIDH_HUMAN 3-hydroxyisobutyrate dehydrogenas...2100.002     44.3     23     44GO:0005759; C:mitochondrial matrix; TAS:Reactome.
GO:0008442; F:3-hydroxyisobutyrate dehydrogenase activity; NAS:UniProtKB.::GO:0051287; F:NAD binding; IEA:InterPro.::GO:0004616; F:phosphogluconate dehydrogenase (decarboxylating) activity; IEA:InterPro.
GO:0009083; P:branched chain family amino acid catabolic process; TAS:Reactome.::GO:0006098; P:pentose-phosphate shunt; IEA:InterPro.::GO:0006573; P:valine metabolic process; NAS:UniProtKB.
62Q5R5E7    336   3HIDH_PONAB 3-hydroxyisobutyrate dehydrogenas...2100.002     44.3     23     44GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.
GO:0008442; F:3-hydroxyisobutyrate dehydrogenase activity; IEA:EC.::GO:0051287; F:NAD binding; IEA:InterPro.::GO:0004616; F:phosphogluconate dehydrogenase (decarboxylating) activity; IEA:InterPro.
GO:0006098; P:pentose-phosphate shunt; IEA:InterPro.::GO:0006573; P:valine metabolic process; IEA:InterPro.
63Q2HJD7    336   3HIDH_BOVIN 3-hydroxyisobutyrate dehydrogenas...2100.002     44.3     23     44GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.
GO:0008442; F:3-hydroxyisobutyrate dehydrogenase activity; IEA:EC.::GO:0051287; F:NAD binding; IEA:InterPro.::GO:0004616; F:phosphogluconate dehydrogenase (decarboxylating) activity; IEA:InterPro.
GO:0006098; P:pentose-phosphate shunt; IEA:InterPro.
64Q9V8M5    324   3HIDH_DROME Probable 3-hydroxyisobutyrate deh...2070.007     42.4     24     44GO:0005811; C:lipid particle; IDA:FlyBase.::GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.
GO:0008442; F:3-hydroxyisobutyrate dehydrogenase activity; IEA:EC.::GO:0051287; F:NAD binding; IEA:InterPro.::GO:0004616; F:phosphogluconate dehydrogenase (decarboxylating) activity; IEA:InterPro.
GO:0006098; P:pentose-phosphate shunt; IEA:InterPro.::GO:0006573; P:valine metabolic process; IEA:InterPro.
65Q99L13    335   3HIDH_MOUSE 3-hydroxyisobutyrate dehydrogenas...2040.007     42.4     21     42GO:0005739; C:mitochondrion; IDA:MGI.
GO:0008442; F:3-hydroxyisobutyrate dehydrogenase activity; IEA:EC.::GO:0051287; F:NAD binding; IEA:InterPro.::GO:0004616; F:phosphogluconate dehydrogenase (decarboxylating) activity; IEA:InterPro.
GO:0006098; P:pentose-phosphate shunt; IEA:InterPro.::GO:0006573; P:valine metabolic process; IEA:InterPro.
66P29266    335   3HIDH_RAT 3-hydroxyisobutyrate dehydrogenase,...2060.011     41.6     23     42GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.
GO:0008442; F:3-hydroxyisobutyrate dehydrogenase activity; IEA:EC.::GO:0051287; F:NAD binding; IEA:InterPro.::GO:0004616; F:phosphogluconate dehydrogenase (decarboxylating) activity; IEA:InterPro.
GO:0006098; P:pentose-phosphate shunt; IEA:InterPro.::GO:0006573; P:valine metabolic process; IEA:InterPro.
67P77161    292   GLXR_ECOLI 2-hydroxy-3-oxopropionate reductas...2080.029     40     24     42
GO:0008679; F:2-hydroxy-3-oxopropionate reductase activity; IDA:EcoCyc.::GO:0008442; F:3-hydroxyisobutyrate dehydrogenase activity; IEA:InterPro.::GO:0050662; F:coenzyme binding; IEA:InterPro.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0004616; F:phosphogluconate dehydrogenase (decarboxylating) activity; IEA:InterPro.
GO:0009442; P:allantoin assimilation pathway; IEP:EcoCyc.::GO:0009436; P:glyoxylate catabolic process; IMP:EcoCyc.::GO:0006098; P:pentose-phosphate shunt; IEA:InterPro.::GO:0006573; P:valine metabolic process; IEA:InterPro.
68Q5RKH0    552   GLYR1_RAT Putative oxidoreductase GLYR1 OS=Ra...2390.035     40.4     22     41GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0050662; F:coenzyme binding; IEA:InterPro.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0035064; F:methylated histone residue binding; ISS:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0004616; F:phosphogluconate dehydrogenase (decarboxylating) activity; IEA:InterPro.
GO:0006098; P:pentose-phosphate shunt; IEA:InterPro.
69A4FUF0    553   GLYR1_BOVIN Putative oxidoreductase GLYR1 OS=...2390.047     40     22     41GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0050662; F:coenzyme binding; IEA:InterPro.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0035064; F:methylated histone residue binding; ISS:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0004616; F:phosphogluconate dehydrogenase (decarboxylating) activity; IEA:InterPro.
GO:0006098; P:pentose-phosphate shunt; IEA:InterPro.
70Q5ZLS7    553   GLYR1_CHICK Putative oxidoreductase GLYR1 OS=...2390.059     39.7     22     41GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0050662; F:coenzyme binding; IEA:InterPro.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0035064; F:methylated histone residue binding; ISS:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0004616; F:phosphogluconate dehydrogenase (decarboxylating) activity; IEA:InterPro.
GO:0006098; P:pentose-phosphate shunt; IEA:InterPro.
71Q49A26    553   GLYR1_HUMAN Putative oxidoreductase GLYR1 OS=...2390.073     39.3     22     41GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0050662; F:coenzyme binding; IEA:InterPro.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0035064; F:methylated histone residue binding; IDA:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0004616; F:phosphogluconate dehydrogenase (decarboxylating) activity; IEA:InterPro.
GO:0006098; P:pentose-phosphate shunt; IEA:InterPro.
72Q5R7T2    553   GLYR1_PONAB Putative oxidoreductase GLYR1 OS=...2390.11     38.9     21     42GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0050662; F:coenzyme binding; IEA:InterPro.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0035064; F:methylated histone residue binding; ISS:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0004616; F:phosphogluconate dehydrogenase (decarboxylating) activity; IEA:InterPro.
GO:0006098; P:pentose-phosphate shunt; IEA:InterPro.
73Q9V3L1    1048   NDST_DROME Bifunctional heparan sulfate N-dea...360.56     36.6     44     64GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0015016; F:[heparan sulfate-glucosamine N-sulfotransferase activity; TAS:FlyBase.::GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
GO:0007427; P:epithelial cell migration, open tracheal system; IMP:UniProtKB.::GO:0008543; P:fibroblast growth factor receptor signaling pathway; IMP:UniProtKB.::GO:0006024; P:glycosaminoglycan biosynthetic process; IMP:UniProtKB.::GO:0007507; P:heart development; NAS:FlyBase.::GO:0015014; P:heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process; IMP:UniProtKB.::GO:0008587; P:imaginal disc-derived wing margin morphogenesis; IMP:FlyBase.::GO:0007474; P:imaginal disc-derived wing vein specification; IMP:FlyBase.::GO:0048312; P:intracellular distribution of mitochondria; IMP:FlyBase.::GO:0007509; P:mesoderm migration involved in gastrulation; IMP:UniProtKB.::GO:0007428; P:primary branching, open tracheal system; TAS:FlyBase.::GO:0060828; P:regulation of canonical Wnt receptor signaling pathway; IMP:FlyBase.::GO:0090097; P:regulation of decapentaplegic signaling pathway; IMP:FlyBase.::GO:0045570; P:regulation of imaginal disc growth; IMP:FlyBase.::GO:0007367; P:segment polarity determination; IMP:FlyBase.::GO:0048488; P:synaptic vesicle endocytosis; IMP:FlyBase.::GO:0016055; P:Wnt receptor signaling pathway; IMP:UniProtKB.]
74Q562D5    534   GLYR1_XENTR Putative oxidoreductase GLYR1 OS=...420.66     36.2     38     55GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0050662; F:coenzyme binding; IEA:InterPro.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0035064; F:methylated histone residue binding; ISS:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0004616; F:phosphogluconate dehydrogenase (decarboxylating) activity; IEA:InterPro.
GO:0006098; P:pentose-phosphate shunt; IEA:InterPro.
75Q0QLF5    301   HMGD_EUBBA 2-(hydroxymethyl)glutarate dehydro...2180.92     35.4     23     43
GO:0043718; F:2-hydroxymethylglutarate dehydrogenase activity; IDA:UniProtKB.::GO:0008442; F:3-hydroxyisobutyrate dehydrogenase activity; IEA:InterPro.::GO:0050662; F:coenzyme binding; IEA:InterPro.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0004616; F:phosphogluconate dehydrogenase (decarboxylating) activity; IEA:InterPro.
GO:0051187; P:cofactor catabolic process; IDA:UniProtKB.::GO:0006098; P:pentose-phosphate shunt; IEA:InterPro.::GO:0006573; P:valine metabolic process; IEA:InterPro.
76Q175F8    559   GLYR1_AEDAE Putative oxidoreductase GLYR1 hom...371.2     35.4     38     62
GO:0008442; F:3-hydroxyisobutyrate dehydrogenase activity; IEA:InterPro.::GO:0050662; F:coenzyme binding; IEA:InterPro.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0004616; F:phosphogluconate dehydrogenase (decarboxylating) activity; IEA:InterPro.
GO:0006098; P:pentose-phosphate shunt; IEA:InterPro.::GO:0006573; P:valine metabolic process; IEA:InterPro.
77Q5RKN4    462   GLYR1_DANRE Putative oxidoreductase GLYR1 OS=...581.3     35     31     52GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0050662; F:coenzyme binding; IEA:InterPro.::GO:0035064; F:methylated histone residue binding; ISS:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0004616; F:phosphogluconate dehydrogenase (decarboxylating) activity; IEA:InterPro.
GO:0006098; P:pentose-phosphate shunt; IEA:InterPro.
78A8A9U3    441   HEM1_IGNH4 Glutamyl-tRNA reductase OS=Ignicoc...953.1     33.9     31     55
GO:0008883; F:glutamyl-tRNA reductase activity; IEA:EC.::GO:0050661; F:NADP binding; IEA:InterPro.
GO:0006779; P:porphyrin-containing compound biosynthetic process; IEA:UniProtKB-KW.
79P0ABQ2    294   GARR_ECOLI 2-hydroxy-3-oxopropionate reductas...2174.7     33.1     23     43
GO:0008679; F:2-hydroxy-3-oxopropionate reductase activity; IDA:EcoCyc.::GO:0008442; F:3-hydroxyisobutyrate dehydrogenase activity; IEA:InterPro.::GO:0050662; F:coenzyme binding; IEA:InterPro.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0004616; F:phosphogluconate dehydrogenase (decarboxylating) activity; IEA:InterPro.
GO:0019582; P:D-galactarate catabolic process; IDA:EcoCyc.::GO:0042838; P:D-glucarate catabolic process; IDA:EcoCyc.::GO:0046487; P:glyoxylate metabolic process; IEA:InterPro.::GO:0006098; P:pentose-phosphate shunt; IEA:InterPro.::GO:0006573; P:valine metabolic process; IEA:InterPro.
80P0ABQ3    294   GARR_ECOL6 2-hydroxy-3-oxopropionate reductas...2174.7     33.1     23     43
GO:0008679; F:2-hydroxy-3-oxopropionate reductase activity; IEA:EC.::GO:0008442; F:3-hydroxyisobutyrate dehydrogenase activity; IEA:InterPro.::GO:0050662; F:coenzyme binding; IEA:InterPro.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0004616; F:phosphogluconate dehydrogenase (decarboxylating) activity; IEA:InterPro.
GO:0046487; P:glyoxylate metabolic process; IEA:InterPro.::GO:0006098; P:pentose-phosphate shunt; IEA:InterPro.::GO:0006573; P:valine metabolic process; IEA:InterPro.
81P37741    464   MANC7_ECOLX Mannose-1-phosphate guanylyltrans...975.6     33.1     27     45
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0004475; F:mannose-1-phosphate guanylyltransferase activity; IEA:EC.
GO:0009103; P:lipopolysaccharide biosynthetic process; IEA:UniProtKB-KW.
82Q8RM03    776   ACXB_XANP2 Acetone carboxylase alpha subunit ...926.7     33.1     28     49
GO:0018710; F:acetone carboxylase activity; IDA:UniProtKB.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
GO:0043443; P:acetone metabolic process; IDA:UniProtKB.
83B2G9H5    421   HEM1_LACRJ Glutamyl-tRNA reductase OS=Lactoba...977.2     32.7     30     51
GO:0008883; F:glutamyl-tRNA reductase activity; IEA:EC.::GO:0050661; F:NADP binding; IEA:InterPro.
GO:0006779; P:porphyrin-containing compound biosynthetic process; IEA:UniProtKB-KW.
84A5VM68    421   HEM1_LACRD Glutamyl-tRNA reductase OS=Lactoba...977.2     32.7     30     51
GO:0008883; F:glutamyl-tRNA reductase activity; IEA:EC.::GO:0050661; F:NADP binding; IEA:InterPro.
GO:0006779; P:porphyrin-containing compound biosynthetic process; IEA:UniProtKB-KW.
85Q7Q161    566   GLYR1_ANOGA Putative oxidoreductase GLYR1 hom...378.8     32.7     38     57
GO:0050662; F:coenzyme binding; IEA:InterPro.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0004616; F:phosphogluconate dehydrogenase (decarboxylating) activity; IEA:InterPro.
GO:0006098; P:pentose-phosphate shunt; IEA:InterPro.
records
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