UniProt_SwissProt BLAST: Single locus

Species:

Saccharomyces cerevisiae S288C

Locus:

YGR255C

Length:

479

Number of sequences:

5887

Description:

YGR255C COQ6 SGDID:S000003487, Chr VII from 1003962-1002523, Genome Release 64-1-1, reverse complement, Verified ORF, "Putative flavin-dependent monooxygenase; involved in ubiquinone (Coenzyme Q) biosynthesis; localizes to the matrix face of the mitochondrial inner membrane in a large complex with other ubiquinone biosynthetic enzymes; human COX6 can rescue a yeast cox6 mutant and is implicated in steroid-resistant nephrotic syndrome (SRNS)"

rec.	Subject	Hit Length	Description	Align.Len	E value	Bit score	% ident.	% pos.	GO associations
1	P53318	479	COQ6_YEAST Ubiquinone biosynthesis monooxygen...	479	0	986	100	100	GO:0005743; C:mitochondrial inner membrane; IDA:SGD.
									GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0016709; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen; IEA:InterPro.
									GO:0006744; P:ubiquinone biosynthetic process; IMP:SGD.
2	Q9Y7Z9	466	COQ6_SCHPO Probable ubiquinone biosynthesis m...	482	3e-88	284	37	56	GO:0005743; C:mitochondrial inner membrane; ISS:PomBase.
									GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0016709; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen; ISS:PomBase.
									GO:0006744; P:ubiquinone biosynthetic process; ISS:PomBase.
3	Q8R1S0	469	COQ6_MOUSE Ubiquinone biosynthesis monooxygen...	480	2e-65	224	34	51
									GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0016709; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen; IEA:InterPro.
									GO:0006744; P:ubiquinone biosynthetic process; IEA:UniProtKB-KW.
4	O01884	451	COQ6_CAEEL Probable ubiquinone biosynthesis m...	464	8e-65	222	33	50
									GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0016709; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen; IEA:InterPro.
									GO:0008340; P:determination of adult lifespan; IMP:WormBase.::GO:0006744; P:ubiquinone biosynthetic process; IMP:WormBase.
5	Q9Y2Z9	468	COQ6_HUMAN Ubiquinone biosynthesis monooxygen...	409	4e-64	221	34	51	GO:0005739; C:mitochondrion; IDA:LIFEdb.
									GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0016709; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen; IEA:InterPro.
									GO:0006744; P:ubiquinone biosynthetic process; IEA:UniProtKB-KW.
6	Q2KIL4	469	COQ6_BOVIN Ubiquinone biosynthesis monooxygen...	399	3e-63	218	34	52
									GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0016709; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen; IEA:InterPro.
									GO:0006744; P:ubiquinone biosynthetic process; IEA:UniProtKB-KW.
7	Q9VMQ5	477	COQ6_DROME Putative ubiquinone biosynthesis m...	436	2e-50	184	29	49
									GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0016709; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen; IEA:InterPro.
									GO:0006744; P:ubiquinone biosynthetic process; IEA:UniProtKB-KW.
8	Q54EN1	495	COQ6_DICDI Ubiquinone biosynthesis monooxygen...	466	3e-50	184	30	48
									GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0016709; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen; IEA:InterPro.
									GO:0006744; P:ubiquinone biosynthetic process; IEA:UniProtKB-KW.
9	P72835	414	Y1300_SYNY3 Uncharacterized protein slr1300 O...	460	2e-34	137	25	43
									GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0016709; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen; IEA:InterPro.
									GO:0006744; P:ubiquinone biosynthetic process; IEA:InterPro.
10	P75728	391	UBIF_ECOLI 2-octaprenyl-3-methyl-6-methoxy-1,...	451	8e-30	123	25	42
									GO:0008682; F:2-octoprenyl-3-methyl-6-methoxy-1,4-benzoquinone hydroxylase activity; IMP:EcoliWiki.::GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0016709; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen; IEA:InterPro.
									GO:0006744; P:ubiquinone biosynthetic process; IMP:EcoCyc.
11	P25535	400	VISC_ECOLI Protein visC OS=Escherichia coli (...	458	3e-28	119	25	42
									GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0016709; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen; IEA:InterPro.
									GO:0006744; P:ubiquinone biosynthetic process; IEA:InterPro.
12	P25534	392	UBIH_ECOLI 2-octaprenyl-6-methoxyphenol hydro...	453	5e-28	118	25	40
									GO:0008681; F:2-octaprenyl-6-methoxyphenol hydroxylase activity; IMP:EcoCyc.::GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0016709; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen; IEA:InterPro.
									GO:0009416; P:response to light stimulus; IMP:EcoliWiki.::GO:0006979; P:response to oxidative stress; IMP:EcoliWiki.::GO:0006744; P:ubiquinone biosynthetic process; IMP:EcoCyc.
13	A4JQH4	546	MHPA2_BURVG 3-(3-hydroxy-phenyl)propionate/3-...	144	0.000002	53.9	33	47
									GO:0008688; F:3-(3-hydroxyphenyl)propionate hydroxylase activity; IEA:InterPro.
									GO:0019622; P:3-(3-hydroxy)phenylpropionate catabolic process; IEA:InterPro.::GO:0019439; P:aromatic compound catabolic process; IEA:UniProtKB-KW.
14	O07561	499	YHJG_BACSU Uncharacterized aromatic compound ...	92	0.00005	49.3	37	50
									GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.
									GO:0019439; P:aromatic compound catabolic process; IEA:UniProtKB-KW.
15	A0KE38	542	MHPA_BURCH 3-(3-hydroxy-phenyl)propionate/3-h...	162	0.0001	48.1	30	44
									GO:0008688; F:3-(3-hydroxyphenyl)propionate hydroxylase activity; IEA:InterPro.
									GO:0019622; P:3-(3-hydroxy)phenylpropionate catabolic process; IEA:InterPro.::GO:0019439; P:aromatic compound catabolic process; IEA:UniProtKB-KW.
16	Q1BGA7	542	MHPA_BURCA 3-(3-hydroxy-phenyl)propionate/3-h...	162	0.0001	48.1	30	44
									GO:0008688; F:3-(3-hydroxyphenyl)propionate hydroxylase activity; IEA:InterPro.
									GO:0019622; P:3-(3-hydroxy)phenylpropionate catabolic process; IEA:InterPro.::GO:0019439; P:aromatic compound catabolic process; IEA:UniProtKB-KW.
17	A1Z746	465	KMO_DROME Kynurenine 3-monooxygenase OS=Droso...	114	0.0006	45.8	27	47	GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005741; C:mitochondrial outer membrane; ISS:UniProtKB.
									GO:0004502; F:kynurenine 3-monooxygenase activity; ISS:UniProtKB.
									GO:0048072; P:compound eye pigmentation; TAS:FlyBase.::GO:0019674; P:NAD metabolic process; ISS:UniProtKB.::GO:0006727; P:ommochrome biosynthetic process; IMP:FlyBase.::GO:0019363; P:pyridine nucleotide biosynthetic process; IEA:UniProtKB-KW.::GO:0006569; P:tryptophan catabolic process; TAS:FlyBase.
18	A8LVF4	454	KMO_SALAI Kynurenine 3-monooxygenase OS=Salin...	200	0.003	43.5	26	40
									GO:0004502; F:kynurenine 3-monooxygenase activity; IEA:EC.
									GO:0019363; P:pyridine nucleotide biosynthetic process; IEA:UniProtKB-KW.
19	Q03298	404	PHHY_ACIAD p-hydroxybenzoate hydroxylase OS=A...	415	0.004	43.1	24	40
									GO:0018659; F:4-hydroxybenzoate 3-monooxygenase activity; IEA:EC.::GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.
									GO:0019439; P:aromatic compound catabolic process; IEA:UniProtKB-KW.::GO:0043639; P:benzoate catabolic process; IEA:InterPro.
20	Q5B2N0	506	KMO_EMENI Kynurenine 3-monooxygenase OS=194 /...	107	0.004	43.1	35	47	GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.
									GO:0004502; F:kynurenine 3-monooxygenase activity; IEA:EC.
									GO:0019363; P:pyridine nucleotide biosynthetic process; IEA:UniProtKB-KW.
21	Q4P0N0	600	KMO_USTMA Kynurenine 3-monooxygenase OS=Ustil...	76	0.012	42	36	53	GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.
									GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0004502; F:kynurenine 3-monooxygenase activity; IEA:EC.
									GO:0019363; P:pyridine nucleotide biosynthetic process; IEA:UniProtKB-KW.
22	A1CT23	512	KMO_ASPCL Kynurenine 3-monooxygenase OS=3887 ...	75	0.015	41.6	37	45	GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.
									GO:0004502; F:kynurenine 3-monooxygenase activity; IEA:EC.
									GO:0019363; P:pyridine nucleotide biosynthetic process; IEA:UniProtKB-KW.
23	P93236	669	ABA2_SOLLC Zeaxanthin epoxidase, chloroplasti...	72	0.018	41.2	36	49	GO:0009507; C:chloroplast; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:InterPro.
									GO:0052663; F:antheraxanthin epoxidase activity; IEA:EC.::GO:0009540; F:zeaxanthin epoxidase [overall activity; IEA:EC.::GO:0052662; F:zeaxanthin epoxidase activity; IEA:EC.
									GO:0009688; P:abscisic acid biosynthetic process; IEA:UniProtKB-KW.]
24	A6H1P4	447	KMO_FLAPJ Kynurenine 3-monooxygenase OS=Flavo...	29	0.024	40.8	55	72
									GO:0004502; F:kynurenine 3-monooxygenase activity; IEA:EC.
									GO:0019363; P:pyridine nucleotide biosynthetic process; IEA:UniProtKB-KW.
25	A5FMP6	446	KMO_FLAJ1 Kynurenine 3-monooxygenase OS=(Cyto...	37	0.035	40	46	62
									GO:0004502; F:kynurenine 3-monooxygenase activity; IEA:EC.
									GO:0019363; P:pyridine nucleotide biosynthetic process; IEA:UniProtKB-KW.
26	Q96375	660	ABA2_CAPAN Zeaxanthin epoxidase, chloroplasti...	72	0.048	40	36	49	GO:0031969; C:chloroplast membrane; IEA:UniProtKB-SubCell.::GO:0009535; C:chloroplast thylakoid membrane; IEA:UniProtKB-SubCell.
									GO:0052663; F:antheraxanthin epoxidase activity; IEA:EC.::GO:0009540; F:zeaxanthin epoxidase [overall activity; IEA:EC.::GO:0052662; F:zeaxanthin epoxidase activity; IEA:EC.
									GO:0009688; P:abscisic acid biosynthetic process; IEA:UniProtKB-KW.]
27	Q4WN75	512	KMO_ASPFU Kynurenine 3-monooxygenase OS=A1100...	42	0.05	39.7	45	55	GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.
									GO:0004502; F:kynurenine 3-monooxygenase activity; IEA:EC.
									GO:0019363; P:pyridine nucleotide biosynthetic process; IEA:UniProtKB-KW.
28	B0Y7C3	512	KMO_ASPFC Kynurenine 3-monooxygenase OS=(Aspe...	42	0.05	39.7	45	55	GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.
									GO:0004502; F:kynurenine 3-monooxygenase activity; IEA:EC.
									GO:0019363; P:pyridine nucleotide biosynthetic process; IEA:UniProtKB-KW.
29	Q0JCU7	659	ZEP_ORYSJ Zeaxanthin epoxidase, chloroplastic...	130	0.054	39.7	27	45	GO:0031969; C:chloroplast membrane; IEA:UniProtKB-SubCell.::GO:0009535; C:chloroplast thylakoid membrane; IEA:UniProtKB-SubCell.
									GO:0052663; F:antheraxanthin epoxidase activity; IEA:EC.::GO:0009540; F:zeaxanthin epoxidase [overall activity; IEA:EC.::GO:0052662; F:zeaxanthin epoxidase activity; IMP:UniProtKB.
									GO:0009688; P:abscisic acid biosynthetic process; IMP:UniProtKB.::GO:0050891; P:multicellular organismal water homeostasis; IMP:UniProtKB.::GO:0009414; P:response to water deprivation; IMP:UniProtKB.::GO:0016123; P:xanthophyll biosynthetic process; IMP:UniProtKB.]
30	A2Q9N7	475	KMO1_ASPNC Kynurenine 3-monooxygenase 1 OS=As...	88	0.079	39.3	32	41	GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.
									GO:0004502; F:kynurenine 3-monooxygenase activity; IEA:EC.
									GO:0019363; P:pyridine nucleotide biosynthetic process; IEA:UniProtKB-KW.
31	A3LNF8	478	KMO_PICST Kynurenine 3-monooxygenase OS=NRRL ...	252	0.08	38.9	24	38	GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.
									GO:0004502; F:kynurenine 3-monooxygenase activity; IEA:EC.
									GO:0019363; P:pyridine nucleotide biosynthetic process; IEA:UniProtKB-KW.

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