UniProt_SwissProt BLAST: Single locus

Species:

Saccharomyces cerevisiae S288C

Locus:

YGR253C

Length:

260

Number of sequences:

5887

Description:

YGR253C PUP2 SGDID:S000003485, Chr VII from 999140-998358, Genome Release 64-1-1, reverse complement, Verified ORF, "Alpha 5 subunit of the 20S proteasome involved in ubiquitin-dependent catabolism; human homolog is subunit zeta"

rec.	Subject	Hit Length	Description	Align.Len	E value	Bit score	% ident.	% pos.	GO associations
91	Q6L0W3	234	PSA_PICTO Proteasome subunit alpha OS=100828)...	233	1e-40	145	35	58	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0019773; C:proteasome core complex, alpha-subunit complex; IEA:InterPro.
									GO:0004298; F:threonine-type endopeptidase activity; IEA:UniProtKB-KW.
									GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
92	Q10329	259	PSA7_SCHPO Probable proteasome subunit alpha ...	247	2e-40	145	33	55	GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.::GO:0019773; C:proteasome core complex, alpha-subunit complex; IDA:PomBase.
									GO:0004298; F:threonine-type endopeptidase activity; IEA:UniProtKB-KW.
									GO:0043161; P:proteasomal ubiquitin-dependent protein catabolic process; ISS:PomBase.::GO:0007346; P:regulation of mitotic cell cycle; IC:PomBase.
93	Q9U793	231	PSA2_TRYBB Proteasome subunit alpha type-2 OS...	214	2e-40	145	35	57	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0019773; C:proteasome core complex, alpha-subunit complex; IEA:InterPro.
									GO:0004298; F:threonine-type endopeptidase activity; IEA:UniProtKB-KW.
									GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
94	Q24178	249	PSA72_DROME Proteasome subunit alpha type-7-1...	245	7e-40	144	34	56	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0019773; C:proteasome core complex, alpha-subunit complex; IEA:InterPro.
									GO:0004298; F:threonine-type endopeptidase activity; IEA:UniProtKB-KW.
									GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
95	Q9V2V5	249	PSA2_HALVD Proteasome subunit alpha 2 OS=1474...	235	8e-40	144	37	58	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0019773; C:proteasome core complex, alpha-subunit complex; IDA:UniProtKB.
									GO:0004298; F:threonine-type endopeptidase activity; IEA:UniProtKB-KW.
									GO:0010498; P:proteasomal protein catabolic process; IDA:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
96	P23638	258	PSA4_YEAST Proteasome component Y13 OS=Saccha...	204	9e-40	144	40	59	GO:0005739; C:mitochondrion; IC:SGD.::GO:0042175; C:nuclear outer membrane-endoplasmic reticulum membrane network; IC:SGD.::GO:0005634; C:nucleus; IC:SGD.::GO:0019773; C:proteasome core complex, alpha-subunit complex; IDA:SGD.::GO:0034515; C:proteasome storage granule; IDA:SGD.
									GO:0005515; F:protein binding; IPI:IntAct.::GO:0004298; F:threonine-type endopeptidase activity; IEA:UniProtKB-KW.
									GO:0043161; P:proteasomal ubiquitin-dependent protein catabolic process; IDA:SGD.::GO:0010499; P:proteasomal ubiquitin-independent protein catabolic process; IDA:SGD.::GO:0080129; P:proteasome core complex assembly; IMP:SGD.
97	P48004	254	PSA7_RAT Proteasome subunit alpha type-7 OS=R...	236	1e-39	144	36	59	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0019773; C:proteasome core complex, alpha-subunit complex; IEA:InterPro.
									GO:0004298; F:threonine-type endopeptidase activity; IEA:UniProtKB-KW.
									GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
98	Q8SRU3	232	PSA5_ENCCU Probable proteasome subunit alpha ...	210	2e-39	142	38	63	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0019773; C:proteasome core complex, alpha-subunit complex; IEA:InterPro.
									GO:0004298; F:threonine-type endopeptidase activity; IEA:UniProtKB-KW.
									GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
99	Q27575	252	PSA73_DROME Proteasome subunit alpha type-7-1...	251	7e-39	141	31	54	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0019773; C:proteasome core complex, alpha-subunit complex; IEA:InterPro.
									GO:0004298; F:threonine-type endopeptidase activity; IEA:UniProtKB-KW.
									GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
100	P25789	261	PSA4_HUMAN Proteasome subunit alpha type-4 OS...	244	3e-38	140	34	55	GO:0005829; C:cytosol; TAS:Reactome.::GO:0005654; C:nucleoplasm; TAS:Reactome.::GO:0019773; C:proteasome core complex, alpha-subunit complex; IEA:InterPro.
									GO:0005515; F:protein binding; IPI:IntAct.::GO:0004298; F:threonine-type endopeptidase activity; IEA:UniProtKB-KW.
									GO:0031145; P:anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; TAS:Reactome.::GO:0002479; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; TAS:Reactome.::GO:0006915; P:apoptotic process; TAS:Reactome.::GO:0006977; P:DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest; TAS:Reactome.::GO:0000082; P:G1/S transition of mitotic cell cycle; TAS:Reactome.::GO:0010467; P:gene expression; TAS:Reactome.::GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW.::GO:0000216; P:M/G1 transition of mitotic cell cycle; TAS:Reactome.::GO:0016071; P:mRNA metabolic process; TAS:Reactome.::GO:0051436; P:negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.::GO:0051437; P:positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.::GO:0000209; P:protein polyubiquitination; TAS:Reactome.::GO:0042981; P:regulation of apoptotic process; TAS:Reactome.::GO:0006521; P:regulation of cellular amino acid metabolic process; TAS:Reactome.::GO:0000084; P:S phase of mitotic cell cycle; TAS:Reactome.::GO:0044281; P:small molecule metabolic process; TAS:Reactome.::GO:0016032; P:viral reproduction; TAS:Reactome.
101	Q3ZCK9	261	PSA4_BOVIN Proteasome subunit alpha type-4 OS...	244	3e-38	140	34	55	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0019773; C:proteasome core complex, alpha-subunit complex; IEA:InterPro.
									GO:0004298; F:threonine-type endopeptidase activity; IEA:UniProtKB-KW.
									GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
102	Q8TAA3	256	PSA7L_HUMAN Proteasome subunit alpha type-7-l...	235	3e-38	140	35	57	GO:0005829; C:cytosol; TAS:Reactome.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0019773; C:proteasome core complex, alpha-subunit complex; IEA:InterPro.
									GO:0004298; F:threonine-type endopeptidase activity; IEA:UniProtKB-KW.
									GO:0031145; P:anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; TAS:Reactome.::GO:0002479; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; TAS:Reactome.::GO:0006915; P:apoptotic process; TAS:Reactome.::GO:0006977; P:DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest; TAS:Reactome.::GO:0010467; P:gene expression; TAS:Reactome.::GO:0000216; P:M/G1 transition of mitotic cell cycle; TAS:Reactome.::GO:0016071; P:mRNA metabolic process; TAS:Reactome.::GO:0051437; P:positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.::GO:0000209; P:protein polyubiquitination; TAS:Reactome.::GO:0042981; P:regulation of apoptotic process; TAS:Reactome.::GO:0006521; P:regulation of cellular amino acid metabolic process; TAS:Reactome.::GO:0000084; P:S phase of mitotic cell cycle; TAS:Reactome.::GO:0044281; P:small molecule metabolic process; TAS:Reactome.::GO:0016032; P:viral reproduction; TAS:Reactome.
103	P21670	261	PSA4_RAT Proteasome subunit alpha type-4 OS=R...	244	3e-38	140	34	55	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0019773; C:proteasome core complex, alpha-subunit complex; IEA:InterPro.
									GO:0004298; F:threonine-type endopeptidase activity; IEA:UniProtKB-KW.
									GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
104	P40303	254	PSA7_YEAST Proteasome component PRE6 OS=Sacch...	209	3e-38	140	38	59	GO:0005739; C:mitochondrion; IDA:SGD.::GO:0042175; C:nuclear outer membrane-endoplasmic reticulum membrane network; IDA:SGD.::GO:0005634; C:nucleus; IDA:SGD.::GO:0019773; C:proteasome core complex, alpha-subunit complex; IDA:SGD.::GO:0034515; C:proteasome storage granule; IDA:SGD.
									GO:0005515; F:protein binding; IPI:IntAct.::GO:0004298; F:threonine-type endopeptidase activity; IEA:UniProtKB-KW.
									GO:0043161; P:proteasomal ubiquitin-dependent protein catabolic process; IDA:SGD.::GO:0010499; P:proteasomal ubiquitin-independent protein catabolic process; IDA:SGD.
105	O24362	249	PSA3_SPIOL Proteasome subunit alpha type-3 OS...	236	5e-38	139	36	55	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0019773; C:proteasome core complex, alpha-subunit complex; IEA:InterPro.
									GO:0004298; F:threonine-type endopeptidase activity; IEA:UniProtKB-KW.
									GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
106	P30186	250	PSA7A_ARATH Proteasome subunit alpha type-7-A...	243	5e-38	139	34	56	GO:0009507; C:chloroplast; IDA:TAIR.::GO:0022626; C:cytosolic ribosome; IDA:TAIR.::GO:0005634; C:nucleus; IDA:TAIR.::GO:0009524; C:phragmoplast; IDA:TAIR.::GO:0019773; C:proteasome core complex, alpha-subunit complex; IEA:InterPro.::GO:0005819; C:spindle; IDA:TAIR.::GO:0005774; C:vacuolar membrane; IDA:TAIR.
									GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004298; F:threonine-type endopeptidase activity; IEA:UniProtKB-KW.
									GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
107	Q9R1P0	261	PSA4_MOUSE Proteasome subunit alpha type-4 OS...	244	7e-38	139	34	55	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0019773; C:proteasome core complex, alpha-subunit complex; IEA:InterPro.
									GO:0004298; F:threonine-type endopeptidase activity; IEA:UniProtKB-KW.
									GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
108	Q4R932	261	PSA4_MACFA Proteasome subunit alpha type-4 OS...	244	7e-38	139	34	55	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0019773; C:proteasome core complex, alpha-subunit complex; IEA:InterPro.
									GO:0004298; F:threonine-type endopeptidase activity; IEA:UniProtKB-KW.
									GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
109	O23712	277	PSA1B_ARATH Proteasome subunit alpha type-1-B...	241	2e-37	138	34	55	GO:0005829; C:cytosol; IDA:TAIR.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IDA:TAIR.::GO:0009506; C:plasmodesma; IDA:TAIR.::GO:0019773; C:proteasome core complex, alpha-subunit complex; IEA:InterPro.
									GO:0004298; F:threonine-type endopeptidase activity; IEA:UniProtKB-KW.
									GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
110	O24616	250	PSA7B_ARATH Proteasome subunit alpha type-7-B...	222	3e-37	137	35	57	GO:0009507; C:chloroplast; IDA:TAIR.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0019773; C:proteasome core complex, alpha-subunit complex; IEA:InterPro.::GO:0005773; C:vacuole; IDA:TAIR.
									GO:0004298; F:threonine-type endopeptidase activity; IEA:UniProtKB-KW.
									GO:0006511; P:ubiquitin-dependent protein catabolic process; TAS:TAIR.
111	P40301	234	PSA2_DROME Proteasome subunit alpha type-2 OS...	226	3e-37	137	35	53	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0019773; C:proteasome core complex, alpha-subunit complex; IEA:InterPro.
									GO:0005515; F:protein binding; IPI:IntAct.::GO:0004298; F:threonine-type endopeptidase activity; IEA:UniProtKB-KW.
									GO:0008283; P:cell proliferation; IMP:FlyBase.::GO:0000022; P:mitotic spindle elongation; IMP:FlyBase.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
112	O16811	247	PSA71_DROVI Proteasome subunit alpha type-7-1...	172	3e-37	137	41	60	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0019773; C:proteasome core complex, alpha-subunit complex; IEA:InterPro.
									GO:0004298; F:threonine-type endopeptidase activity; IEA:UniProtKB-KW.
									GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
113	Q9LSU0	249	PSA3_ORYSJ Proteasome subunit alpha type-3 OS...	213	7e-37	136	37	55	GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0019773; C:proteasome core complex, alpha-subunit complex; IEA:InterPro.
									GO:0004298; F:threonine-type endopeptidase activity; IEA:UniProtKB-KW.
									GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
114	O23715	249	PSA3_ARATH Proteasome subunit alpha type-3 OS...	213	8e-37	136	36	56	GO:0048046; C:apoplast; IDA:TAIR.::GO:0005829; C:cytosol; IDA:TAIR.::GO:0005634; C:nucleus; IDA:TAIR.::GO:0019773; C:proteasome core complex, alpha-subunit complex; IEA:InterPro.::GO:0005774; C:vacuolar membrane; IDA:TAIR.
									GO:0004298; F:threonine-type endopeptidase activity; IEA:UniProtKB-KW.
									GO:0046686; P:response to cadmium ion; IEP:TAIR.::GO:0009409; P:response to cold; IEP:TAIR.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
115	P23639	250	PSA2_YEAST Proteasome component Y7 OS=Sacchar...	216	9e-37	135	34	56	GO:0005739; C:mitochondrion; IC:SGD.::GO:0042175; C:nuclear outer membrane-endoplasmic reticulum membrane network; IC:SGD.::GO:0005634; C:nucleus; IC:SGD.::GO:0019773; C:proteasome core complex, alpha-subunit complex; IDA:SGD.::GO:0034515; C:proteasome storage granule; IDA:SGD.
									GO:0005515; F:protein binding; IPI:IntAct.::GO:0004298; F:threonine-type endopeptidase activity; IEA:UniProtKB-KW.
									GO:0043161; P:proteasomal ubiquitin-dependent protein catabolic process; IDA:SGD.::GO:0010499; P:proteasomal ubiquitin-independent protein catabolic process; IDA:SGD.
116	O70435	255	PSA3_MOUSE Proteasome subunit alpha type-3 OS...	250	1e-36	136	36	55	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0019773; C:proteasome core complex, alpha-subunit complex; IEA:InterPro.
									GO:0005515; F:protein binding; IPI:MGI.::GO:0004298; F:threonine-type endopeptidase activity; IEA:UniProtKB-KW.
									GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
117	P34066	278	PSA1A_ARATH Proteasome subunit alpha type-1-A...	241	2e-36	136	34	54	GO:0005829; C:cytosol; IDA:TAIR.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IDA:TAIR.::GO:0019773; C:proteasome core complex, alpha-subunit complex; IEA:InterPro.
									GO:0004298; F:threonine-type endopeptidase activity; IEA:UniProtKB-KW.
									GO:0046685; P:response to arsenic-containing substance; IMP:TAIR.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
118	Q27562	248	PSA1_DICDI Proteasome subunit alpha type-1 OS...	253	3e-36	134	32	53	GO:0005634; C:nucleus; IPI:dictyBase.::GO:0045335; C:phagocytic vesicle; IDA:dictyBase.::GO:0019773; C:proteasome core complex, alpha-subunit complex; ISS:dictyBase.
									GO:0004298; F:threonine-type endopeptidase activity; IEA:UniProtKB-KW.
									GO:0006511; P:ubiquitin-dependent protein catabolic process; ISS:dictyBase.
119	P25788	255	PSA3_HUMAN Proteasome subunit alpha type-3 OS...	250	3e-36	134	35	54	GO:0005829; C:cytosol; TAS:Reactome.::GO:0005654; C:nucleoplasm; TAS:Reactome.::GO:0019773; C:proteasome core complex, alpha-subunit complex; IEA:InterPro.
									GO:0005515; F:protein binding; IPI:IntAct.::GO:0004298; F:threonine-type endopeptidase activity; IEA:UniProtKB-KW.
									GO:0031145; P:anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; TAS:Reactome.::GO:0002479; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; TAS:Reactome.::GO:0006915; P:apoptotic process; TAS:Reactome.::GO:0006977; P:DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest; TAS:Reactome.::GO:0000082; P:G1/S transition of mitotic cell cycle; TAS:Reactome.::GO:0010467; P:gene expression; TAS:Reactome.::GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW.::GO:0000216; P:M/G1 transition of mitotic cell cycle; TAS:Reactome.::GO:0016071; P:mRNA metabolic process; TAS:Reactome.::GO:0051436; P:negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.::GO:0051437; P:positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.::GO:0000209; P:protein polyubiquitination; TAS:Reactome.::GO:0042981; P:regulation of apoptotic process; TAS:Reactome.::GO:0006521; P:regulation of cellular amino acid metabolic process; TAS:Reactome.::GO:0000084; P:S phase of mitotic cell cycle; TAS:Reactome.::GO:0044281; P:small molecule metabolic process; TAS:Reactome.::GO:0016032; P:viral reproduction; TAS:Reactome.
120	Q58DU5	255	PSA3_BOVIN Proteasome subunit alpha type-3 OS...	250	5e-36	134	35	54	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0019773; C:proteasome core complex, alpha-subunit complex; IEA:InterPro.
									GO:0004298; F:threonine-type endopeptidase activity; IEA:UniProtKB-KW.
									GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
121	P18422	255	PSA3_RAT Proteasome subunit alpha type-3 OS=R...	250	6e-36	134	35	54	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0019773; C:proteasome core complex, alpha-subunit complex; IEA:InterPro.
									GO:0004298; F:threonine-type endopeptidase activity; IEA:UniProtKB-KW.
									GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.

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