Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YGR252W
Length:
439
Number of sequences:
5887
Description:
YGR252W GCN5 SGDID:S000003484, Chr VII from 996869-998188, Genome Release 64-1-1, Verified ORF, "Acetyltransferase, modifies N-terminal lysines on histones H2B and H3; acetylates Rsc4p, a subunit of the RSC chromatin-remodeling complex, altering replication stress tolerance; catalytic subunit of the ADA and SAGA histone acetyltransferase complexes; founding member of the Gcn5p-related N-acetyltransferase superfamily; mutant displays reduced transcription elongation in the G-less-based run-on (GLRO) assay"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
91Q9ULU4    1186   PKCB1_HUMAN Protein kinase C-binding protein ...800.00000006     58.9     36     56GO:0005634; C:nucleus; ISS:BHF-UCL.
GO:0070491; F:repressing transcription factor binding; ISS:BHF-UCL.::GO:0001106; F:RNA polymerase II transcription corepressor activity; ISS:BHF-UCL.::GO:0008270; F:zinc ion binding; IEA:InterPro.
92Q7Y214    590   GTE7_ARATH Transcription factor GTE7 OS=Arabi...890.00000006     58.5     36     53GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0009294; P:DNA mediated transformation; IMP:TAIR.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
93Q9NPI1    651   BRD7_HUMAN Bromodomain-containing protein 7 O...900.00000008     58.2     36     53GO:0005737; C:cytoplasm; TAS:ProtInc.::GO:0005634; C:nucleus; IDA:UniProtKB.
GO:0070577; F:histone acetyl-lysine binding; IDA:UniProtKB.::GO:0002039; F:p53 binding; IPI:UniProtKB.::GO:0003713; F:transcription coactivator activity; IDA:UniProtKB.::GO:0003714; F:transcription corepressor activity; IDA:UniProtKB.::GO:0008134; F:transcription factor binding; IDA:MGI.::GO:0044212; F:transcription regulatory region DNA binding; IDA:UniProtKB.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0008285; P:negative regulation of cell proliferation; IDA:UniProtKB.::GO:2000134; P:negative regulation of G1/S transition of mitotic cell cycle; IDA:UniProtKB.::GO:0045892; P:negative regulation of transcription, DNA-dependent; IDA:UniProtKB.::GO:0035066; P:positive regulation of histone acetylation; IDA:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; IDA:UniProtKB.::GO:0006357; P:regulation of transcription from RNA polymerase II promoter; IDA:MGI.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
94Q6NVM8    596   BRD9_XENTR Bromodomain-containing protein 9 O...900.00000008     58.2     36     52
95Q5R8B0    651   BRD7_PONAB Bromodomain-containing protein 7 O...900.00000008     58.2     36     53GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0070577; F:histone acetyl-lysine binding; ISS:UniProtKB.::GO:0002039; F:p53 binding; ISS:UniProtKB.::GO:0003713; F:transcription coactivator activity; ISS:UniProtKB.::GO:0003714; F:transcription corepressor activity; ISS:UniProtKB.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0008285; P:negative regulation of cell proliferation; ISS:UniProtKB.::GO:2000134; P:negative regulation of G1/S transition of mitotic cell cycle; ISS:UniProtKB.::GO:0045892; P:negative regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0035066; P:positive regulation of histone acetylation; ISS:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
96Q67W65    1810   TAF1_ORYSJ Transcription initiation factor TF...720.00000008     58.5     36     60GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003676; F:nucleic acid binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
97Q5ZKG2    651   BRD7_CHICK Bromodomain-containing protein 7 O...900.00000009     58.2     36     53GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
98O88665    651   BRD7_MOUSE Bromodomain-containing protein 7 O...900.0000001     57.8     36     53GO:0005634; C:nucleus; IPI:MGI.
GO:0070577; F:histone acetyl-lysine binding; ISS:UniProtKB.::GO:0002039; F:p53 binding; ISS:UniProtKB.::GO:0003713; F:transcription coactivator activity; ISS:UniProtKB.::GO:0003714; F:transcription corepressor activity; IDA:UniProtKB.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0008285; P:negative regulation of cell proliferation; ISS:UniProtKB.::GO:2000134; P:negative regulation of G1/S transition of mitotic cell cycle; ISS:UniProtKB.::GO:0045892; P:negative regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0035066; P:positive regulation of histone acetylation; ISS:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
99Q8R3B7    951   BRD8_MOUSE Bromodomain-containing protein 8 O...960.0000002     57.4     30     51GO:0035267; C:NuA4 histone acetyltransferase complex; ISS:UniProtKB.
GO:0043968; P:histone H2A acetylation; ISS:UniProtKB.::GO:0043967; P:histone H4 acetylation; ISS:UniProtKB.::GO:0040008; P:regulation of growth; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
100O74350    299   BDC1_SCHPO Bromodomain-containing protein 1 O...790.0000002     56.2     30     57GO:0035267; C:NuA4 histone acetyltransferase complex; IDA:PomBase.::GO:0000790; C:nuclear chromatin; NAS:PomBase.
GO:0016573; P:histone acetylation; IC:PomBase.
101Q6GLP7    527   BRD9_XENLA Bromodomain-containing protein 9 O...900.0000003     56.6     34     52
102Q3UQU0    596   BRD9_MOUSE Bromodomain-containing protein 9 O...850.0000004     56.2     34     54
103Q9H8M2    597   BRD9_HUMAN Bromodomain-containing protein 9 O...850.0000004     55.8     34     54
GO:0003676; F:nucleic acid binding; NAS:UniProtKB.
104Q9LNC4    766   GTE4_ARATH Transcription factor GTE4 OS=Arabi...880.0000006     55.5     35     49GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0007049; P:cell cycle; IMP:TAIR.::GO:0009294; P:DNA mediated transformation; IMP:TAIR.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0048364; P:root development; IMP:TAIR.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
105Q8LRK9    1919   TAF1A_ARATH Transcription initiation factor T...700.0000006     55.8     40     60GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0009294; P:DNA mediated transformation; IMP:TAIR.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
106Q9ULI0    1458   ATD2B_HUMAN ATPase family AAA domain-containi...980.0000007     55.5     35     52
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
107Q6PL18    1390   ATAD2_HUMAN ATPase family AAA domain-containi...560.000001     54.3     43     70GO:0005634; C:nucleus; IDA:HPA.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016887; F:ATPase activity; IEA:EC.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
108Q8CDM1    1040   ATAD2_MOUSE ATPase family AAA domain-containi...560.000002     54.3     43     70GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016887; F:ATPase activity; IEA:EC.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
109Q5RDX4    1091   ATAD2_PONAB ATPase family AAA domain-containi...560.000002     53.9     43     70GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016887; F:ATPase activity; IEA:EC.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
110Q924W6    1242   TRI66_MOUSE Tripartite motif-containing prote...990.000002     53.9     32     51GO:0010369; C:chromocenter; IDA:MGI.::GO:0005634; C:nucleus; IDA:MGI.
GO:0042803; F:protein homodimerization activity; IPI:MGI.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0045892; P:negative regulation of transcription, DNA-dependent; IDA:MGI.
111Q6E2N3    1163   TRI33_DANRE E3 ubiquitin-protein ligase TRIM3...1740.000002     53.9     26     44GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
112O15016    1216   TRI66_HUMAN Tripartite motif-containing prote...1890.000005     52.8     26     43GO:0016235; C:aggresome; IDA:HPA.::GO:0005634; C:nucleus; IDA:HPA.
GO:0008270; F:zinc ion binding; IEA:InterPro.
113Q9UTN6    1199   SNF21_SCHPO Chromatin structure-remodeling co...820.000007     52.4     33     54GO:0000790; C:nuclear chromatin; IC:PomBase.::GO:0016586; C:RSC complex; IDA:PomBase.
GO:0005524; F:ATP binding; IC:PomBase.::GO:0004003; F:ATP-dependent DNA helicase activity; ISS:PomBase.::GO:0000991; F:core RNA polymerase II binding transcription factor activity; ISS:PomBase.::GO:0003677; F:DNA binding; IC:PomBase.
GO:0006338; P:chromatin remodeling; ISS:PomBase.
114O94421    1680   SNF22_SCHPO SWI/SNF chromatin-remodeling comp...800.000008     52     33     59GO:0000790; C:nuclear chromatin; IC:PomBase.::GO:0005819; C:spindle; IDA:PomBase.::GO:0016514; C:SWI/SNF complex; IDA:PomBase.
GO:0005524; F:ATP binding; IC:PomBase.::GO:0000991; F:core RNA polymerase II binding transcription factor activity; ISS:PomBase.::GO:0003677; F:DNA binding; IC:PomBase.::GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
GO:0043044; P:ATP-dependent chromatin remodeling; ISS:PomBase.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IEP:PomBase.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEP:PomBase.::GO:0007131; P:reciprocal meiotic recombination; IMP:PomBase.
115Q6PUA2    1786   TAF1B_ARATH Transcription initiation factor T...700.000009     52     39     59GO:0016020; C:membrane; IDA:TAIR.::GO:0005669; C:transcription factor TFIID complex; TAS:TAIR.
GO:0003712; F:transcription cofactor activity; TAS:TAIR.
GO:0016573; P:histone acetylation; IMP:TAIR.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0009416; P:response to light stimulus; IEP:TAIR.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
116P22082    1703   SNF2_YEAST Transcription regulatory protein S...800.00003     50.1     34     53GO:0016514; C:SWI/SNF complex; IDA:SGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008094; F:DNA-dependent ATPase activity; IDA:SGD.::GO:0004386; F:helicase activity; IEA:UniProtKB-KW.::GO:0070577; F:histone acetyl-lysine binding; IDA:SGD.::GO:0031492; F:nucleosomal DNA binding; IDA:SGD.
GO:0043044; P:ATP-dependent chromatin remodeling; IDA:SGD.::GO:0044109; P:cellular alcohol catabolic process; IMP:SGD.::GO:0006261; P:DNA-dependent DNA replication; IMP:SGD.::GO:0006302; P:double-strand break repair; IMP:SGD.::GO:0042766; P:nucleosome mobilization; IDA:SGD.::GO:0031496; P:positive regulation of mating type switching; IMP:SGD.::GO:0061412; P:positive regulation of transcription from RNA polymerase II promoter in response to amino acid starvation; IMP:SGD.::GO:0042148; P:strand invasion; IMP:SGD.::GO:0005987; P:sucrose catabolic process; IMP:SGD.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
117O74964    803   RSC1_SCHPO Chromatin structure-remodeling com...790.00003     50.1     28     59GO:0000790; C:nuclear chromatin; ISS:PomBase.::GO:0016586; C:RSC complex; IDA:PomBase.
GO:0003677; F:DNA binding; IEA:InterPro.
GO:0006338; P:chromatin remodeling; ISS:PomBase.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IEP:PomBase.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEP:PomBase.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
118P51531    1590   SMCA2_HUMAN Probable global transcription act...800.00003     50.1     26     63GO:0045111; C:intermediate filament cytoskeleton; IDA:HPA.::GO:0071565; C:nBAF complex; ISS:UniProtKB.::GO:0071564; C:npBAF complex; ISS:UniProtKB.::GO:0000790; C:nuclear chromatin; IDA:BHF-UCL.::GO:0005654; C:nucleoplasm; TAS:ProtInc.::GO:0016514; C:SWI/SNF complex; IDA:UniProtKB.::GO:0071778; C:WINAC complex; IDA:BHF-UCL.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008094; F:DNA-dependent ATPase activity; TAS:BHF-UCL.::GO:0004386; F:helicase activity; TAS:ProtInc.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0001105; F:RNA polymerase II transcription coactivator activity; IDA:UniProtKB.::GO:0044212; F:transcription regulatory region DNA binding; IDA:UniProtKB.
GO:0006338; P:chromatin remodeling; TAS:BHF-UCL.::GO:0030308; P:negative regulation of cell growth; IMP:BHF-UCL.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; TAS:BHF-UCL.::GO:0007399; P:nervous system development; IEA:UniProtKB-KW.
119Q20318    1042   LIN49_CAEEL Protein lin-49 OS=Caenorhabditis ...920.00005     49.7     32     46GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0040011; P:locomotion; IMP:WormBase.::GO:0040010; P:positive regulation of growth rate; IMP:WormBase.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0000003; P:reproduction; IMP:WormBase.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
120A7Z019    1606   SMCA4_BOVIN Transcription activator BRG1 OS=B...800.00007     49.3     26     61GO:0071565; C:nBAF complex; ISS:UniProtKB.::GO:0071564; C:npBAF complex; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
121A2AHJ4    1799   BRWD3_MOUSE Bromodomain and WD repeat-contain...1070.002     44.3     25     50
GO:0007010; P:cytoskeleton organization; ISS:UniProtKB.::GO:0008360; P:regulation of cell shape; ISS:UniProtKB.
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