Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YGR252W
Length:
439
Number of sequences:
5887
Description:
YGR252W GCN5 SGDID:S000003484, Chr VII from 996869-998188, Genome Release 64-1-1, Verified ORF, "Acetyltransferase, modifies N-terminal lysines on histones H2B and H3; acetylates Rsc4p, a subunit of the RSC chromatin-remodeling complex, altering replication stress tolerance; catalytic subunit of the ADA and SAGA histone acetyltransferase complexes; founding member of the Gcn5p-related N-acetyltransferase superfamily; mutant displays reduced transcription elongation in the G-less-based run-on (GLRO) assay"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
61Q8IZX4    1826   TAF1L_HUMAN Transcription initiation factor T...970.000003     53.5     29     48GO:0005669; C:transcription factor TFIID complex; IEA:InterPro.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0004402; F:histone acetyltransferase activity; ISS:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.::GO:0017025; F:TBP-class protein binding; IPI:UniProtKB.
GO:0007140; P:male meiosis; IEP:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; IDA:UniProtKB.::GO:0006357; P:regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.::GO:0006352; P:transcription initiation, DNA-dependent; IEA:InterPro.
62P55201    1214   BRPF1_HUMAN Peregrin OS=Homo sapiens (Human)....850.00000000004     68.9     41     59GO:0005737; C:cytoplasm; IDA:HPA.::GO:0070776; C:MOZ/MORF histone acetyltransferase complex; IDA:UniProtKB.::GO:0005886; C:plasma membrane; IDA:HPA.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0043966; P:histone H3 acetylation; IDA:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; IDA:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
63Q6BER5    2266   NU301_CAEEL Nucleosome-remodeling factor subu...880.00000000008     68.2     36     59GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0040027; P:negative regulation of vulval development; IMP:WormBase.::GO:0040010; P:positive regulation of growth rate; IMP:WormBase.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0000003; P:reproduction; IMP:WormBase.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
64Q9S7T1    461   GTE3_ARATH Transcription factor GTE3, chlorop...950.0000000001     66.6     37     53GO:0009507; C:chloroplast; IEA:UniProtKB-SubCell.
GO:0042393; F:histone binding; IPI:TAIR.
GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
65Q9UIG0    1483   BAZ1B_HUMAN Tyrosine-protein kinase BAZ1B OS=...980.0000000002     66.6     32     54GO:0071778; C:WINAC complex; IDA:BHF-UCL.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003682; F:chromatin binding; IDA:UniProtKB.::GO:0070577; F:histone acetyl-lysine binding; IDA:UniProtKB.::GO:0035173; F:histone kinase activity; IDA:UniProtKB.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC.::GO:0032947; F:protein complex scaffold; IDA:BHF-UCL.::GO:0071884; F:vitamin D receptor activator activity; IMP:BHF-UCL.::GO:0042809; F:vitamin D receptor binding; IPI:BHF-UCL.::GO:0008270; F:zinc ion binding; NAS:UniProtKB.
GO:0043044; P:ATP-dependent chromatin remodeling; IDA:BHF-UCL.::GO:0048096; P:chromatin-mediated maintenance of transcription; ISS:BHF-UCL.::GO:0034725; P:DNA replication-dependent nucleosome disassembly; IMP:BHF-UCL.::GO:0006302; P:double-strand break repair; ISS:BHF-UCL.::GO:0003007; P:heart morphogenesis; ISS:BHF-UCL.::GO:0006351; P:transcription, DNA-dependent; NAS:BHF-UCL.
66Q9FT54    369   GTE6_ARATH Transcription factor GTE6 OS=Arabi...920.0000000003     65.5     38     55GO:0005634; C:nucleus; IDA:TAIR.
GO:0004402; F:histone acetyltransferase activity; IDA:TAIR.
GO:0006338; P:chromatin remodeling; IDA:TAIR.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
67Q93YS6    688   GTE9_ARATH Transcription factor GTE9 OS=Arabi...910.0000000004     65.5     37     52GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
68Q02206    625   RSC4_YEAST Chromatin structure-remodeling com...750.0000000005     65.1     41     63GO:0016586; C:RSC complex; IDA:UniProtKB.
GO:0070577; F:histone acetyl-lysine binding; IDA:SGD.
GO:0043044; P:ATP-dependent chromatin remodeling; IDA:UniProtKB.::GO:0000086; P:G2/M transition of mitotic cell cycle; IMP:SGD.::GO:0006337; P:nucleosome disassembly; IDA:SGD.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006368; P:transcription elongation from RNA polymerase II promoter; IDA:SGD.
69Q921C3    2304   BRWD1_MOUSE Bromodomain and WD repeat-contain...1210.002     44.3     26     46GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005515; F:protein binding; IPI:MGI.
GO:0007010; P:cytoskeleton organization; ISS:UniProtKB.::GO:0008360; P:regulation of cell shape; ISS:UniProtKB.::GO:0006357; P:regulation of transcription from RNA polymerase II promoter; IDA:MGI.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
70A8DZJ1    1441   BAZ1B_XENLA Tyrosine-protein kinase BAZ1B OS=...1020.0000000009     64.7     29     53GO:0016585; C:chromatin remodeling complex; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003682; F:chromatin binding; ISS:UniProtKB.::GO:0070577; F:histone acetyl-lysine binding; ISS:UniProtKB.::GO:0035173; F:histone kinase activity; ISS:UniProtKB.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006974; P:response to DNA damage stimulus; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
71Q64127    1051   TIF1A_MOUSE Transcription intermediary factor...980.000000001     64.3     37     54GO:0005737; C:cytoplasm; IDA:MGI.::GO:0005719; C:nuclear euchromatin; IDA:MGI.::GO:0005726; C:perichromatin fibrils; IDA:MGI.
GO:0003682; F:chromatin binding; IDA:MGI.::GO:0034056; F:estrogen response element binding; ISS:UniProtKB.::GO:0070577; F:histone acetyl-lysine binding; ISS:UniProtKB.::GO:0016922; F:ligand-dependent nuclear receptor binding; IDA:MGI.::GO:0002039; F:p53 binding; IPI:UniProtKB.::GO:0004672; F:protein kinase activity; IDA:MGI.::GO:0043565; F:sequence-specific DNA binding; IDA:MGI.::GO:0003713; F:transcription coactivator activity; IDA:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; ISS:UniProtKB.
GO:0055074; P:calcium ion homeostasis; IMP:MGI.::GO:0071391; P:cellular response to estrogen stimulus; ISS:UniProtKB.::GO:0008285; P:negative regulation of cell proliferation; IMP:MGI.::GO:0045892; P:negative regulation of transcription, DNA-dependent; IDA:MGI.::GO:0045893; P:positive regulation of transcription, DNA-dependent; IGI:MGI.::GO:0046777; P:protein autophosphorylation; IDA:MGI.::GO:0030163; P:protein catabolic process; IMP:UniProtKB.::GO:0042981; P:regulation of apoptotic process; IMP:UniProtKB.::GO:0031647; P:regulation of protein stability; IMP:UniProtKB.::GO:0070562; P:regulation of vitamin D receptor signaling pathway; IMP:MGI.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
72O15164    1050   TIF1A_HUMAN Transcription intermediary factor...980.000000001     63.9     37     54GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0003682; F:chromatin binding; IDA:UniProtKB.::GO:0034056; F:estrogen response element binding; IDA:UniProtKB.::GO:0070577; F:histone acetyl-lysine binding; IDA:UniProtKB.::GO:0002039; F:p53 binding; IPI:UniProtKB.::GO:0003713; F:transcription coactivator activity; IDA:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IDA:UniProtKB.
GO:0071391; P:cellular response to estrogen stimulus; IDA:UniProtKB.::GO:0030163; P:protein catabolic process; IMP:UniProtKB.::GO:0042981; P:regulation of apoptotic process; IMP:UniProtKB.::GO:0031647; P:regulation of protein stability; IMP:UniProtKB.::GO:0006366; P:transcription from RNA polymerase II promoter; TAS:ProtInc.
73Q7ZUF2    631   BRD9_DANRE Bromodomain-containing protein 9 O...1120.000000001     63.9     35     50
74Q9LS28    494   GTE12_ARATH Transcription factor GTE12 OS=Ara...880.000000002     62.8     36     53GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
75P34545    2056   CBP1_CAEEL Protein cbp-1 OS=Caenorhabditis el...880.000000003     63.2     36     56GO:0005737; C:cytoplasm; IDA:WormBase.::GO:0005634; C:nucleus; IEA:InterPro.
GO:0004402; F:histone acetyltransferase activity; IDA:WormBase.::GO:0004468; F:lysine N-acetyltransferase activity; IDA:WormBase.::GO:0003712; F:transcription cofactor activity; IEA:InterPro.::GO:0008134; F:transcription factor binding; IPI:WormBase.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006915; P:apoptotic process; IMP:WormBase.::GO:0008340; P:determination of adult lifespan; IMP:WormBase.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0040039; P:inductive cell migration; IMP:WormBase.::GO:0019915; P:lipid storage; IMP:WormBase.::GO:0018996; P:molting cycle, collagen and cuticulin-based cuticle; IMP:WormBase.::GO:0048477; P:oogenesis; IMP:WormBase.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IGI:WormBase.::GO:0007283; P:spermatogenesis; IMP:WormBase.
76Q55C84    1578   Y0170_DICDI Bromodomain-containing protein DD...1370.000000003     63.2     33     45
GO:0005524; F:ATP binding; ISS:dictyBase.::GO:0004672; F:protein kinase activity; ISS:dictyBase.
77Q86U86    1689   PB1_HUMAN Protein polybromo-1 OS=Homo sapiens...730.001     45.4     29     55GO:0000228; C:nuclear chromosome; NAS:UniProtKB.
GO:0003682; F:chromatin binding; NAS:UniProtKB.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0006338; P:chromatin remodeling; TAS:UniProtKB.::GO:0007067; P:mitosis; TAS:UniProtKB.::GO:0008285; P:negative regulation of cell proliferation; IMP:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
78Q56R14    1091   TRI33_XENLA E3 ubiquitin-protein ligase TRIM3...940.000000005     62.4     38     53GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
79Q8BSQ9    1634   PB1_MOUSE Protein polybromo-1 OS=Mus musculus...730.001     45.4     29     55GO:0000776; C:kinetochore; IDA:MGI.::GO:0005634; C:nucleus; IC:MGI.
GO:0003682; F:chromatin binding; IDA:MGI.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0001974; P:blood vessel remodeling; TAS:DFLAT.::GO:0060948; P:cardiac vascular smooth muscle cell development; TAS:DFLAT.::GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0003349; P:epicardium-derived cardiac endothelial cell differentiation; TAS:DFLAT.::GO:0003007; P:heart morphogenesis; TAS:DFLAT.::GO:0008285; P:negative regulation of cell proliferation; ISS:UniProtKB.::GO:0001890; P:placenta development; IMP:MGI.::GO:0045893; P:positive regulation of transcription, DNA-dependent; TAS:DFLAT.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0060979; P:vasculogenesis involved in coronary vascular morphogenesis; TAS:DFLAT.
80Q90941    1633   PB1_CHICK Protein polybromo-1 OS=Gallus gallu...730.0007     45.8     29     56GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
81Q8WWQ0    1821   PHIP_HUMAN PH-interacting protein OS=Homo sap...900.002     44.3     27     50GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0005158; F:insulin receptor binding; NAS:UniProtKB.
GO:0007010; P:cytoskeleton organization; IMP:UniProtKB.::GO:0008286; P:insulin receptor signaling pathway; NAS:UniProtKB.::GO:0043066; P:negative regulation of apoptotic process; ISS:UniProtKB.::GO:0008284; P:positive regulation of cell proliferation; ISS:UniProtKB.::GO:0043568; P:positive regulation of insulin-like growth factor receptor signaling pathway; ISS:UniProtKB.::GO:0045840; P:positive regulation of mitosis; ISS:UniProtKB.::GO:0022604; P:regulation of cell morphogenesis; IMP:UniProtKB.
82Q9LK27    813   GTE8_ARATH Transcription factor GTE8 OS=Arabi...950.00000001     61.2     36     48GO:0009507; C:chloroplast; IDA:TAIR.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
83P35177    1332   SPT7_YEAST Transcriptional activator SPT7 OS=...820.00000001     61.6     35     63GO:0005739; C:mitochondrion; IDA:SGD.::GO:0000124; C:SAGA complex; IDA:SGD.::GO:0046695; C:SLIK (SAGA-like) complex; IDA:SGD.
GO:0005515; F:protein binding; IPI:IntAct.::GO:0005198; F:structural molecule activity; IDA:SGD.
GO:0000747; P:conjugation with cellular fusion; IMP:SGD.::GO:0016573; P:histone acetylation; IDA:SGD.::GO:0006461; P:protein complex assembly; IMP:SGD.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
84Q9UPN9    1127   TRI33_HUMAN E3 ubiquitin-protein ligase TRIM3...1740.00000001     61.2     30     47GO:0005634; C:nucleus; IDA:UniProtKB.
GO:0070410; F:co-SMAD binding; IPI:BHF-UCL.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0070412; F:R-SMAD binding; IPI:BHF-UCL.::GO:0008270; F:zinc ion binding; NAS:UniProtKB.
GO:0030514; P:negative regulation of BMP signaling pathway; IDA:UniProtKB.::GO:0045892; P:negative regulation of transcription, DNA-dependent; NAS:UniProtKB.::GO:0016567; P:protein ubiquitination; IDA:UniProtKB.::GO:0017015; P:regulation of transforming growth factor beta receptor signaling pathway; IDA:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
85Q9NSI6    2320   BRWD1_HUMAN Bromodomain and WD repeat-contain...1370.005     43.1     25     45GO:0005737; C:cytoplasm; IDA:HPA.::GO:0005730; C:nucleolus; IDA:HPA.
GO:0007010; P:cytoskeleton organization; IMP:UniProtKB.::GO:0008360; P:regulation of cell shape; IMP:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
86Q9H0E9    1235   BRD8_HUMAN Bromodomain-containing protein 8 O...880.0000002     57     33     51GO:0005739; C:mitochondrion; IDA:HPA.::GO:0035267; C:NuA4 histone acetyltransferase complex; IDA:UniProtKB.
GO:0004887; F:thyroid hormone receptor activity; TAS:ProtInc.
GO:0007166; P:cell surface receptor signaling pathway; TAS:ProtInc.::GO:0043968; P:histone H2A acetylation; IDA:UniProtKB.::GO:0043967; P:histone H4 acetylation; IDA:UniProtKB.::GO:0040008; P:regulation of growth; IEA:UniProtKB-KW.
87Q8VDD9    1821   PHIP_MOUSE PH-interacting protein OS=Mus musc...900.003     43.5     27     49GO:0005634; C:nucleus; IDA:UniProtKB.
GO:0005515; F:protein binding; IPI:IntAct.
GO:0007010; P:cytoskeleton organization; ISS:UniProtKB.::GO:0043066; P:negative regulation of apoptotic process; IDA:UniProtKB.::GO:0008284; P:positive regulation of cell proliferation; IMP:UniProtKB.::GO:0043568; P:positive regulation of insulin-like growth factor receptor signaling pathway; IDA:UniProtKB.::GO:0045840; P:positive regulation of mitosis; IMP:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; IDA:UniProtKB.::GO:0022604; P:regulation of cell morphogenesis; ISS:UniProtKB.::GO:0001932; P:regulation of protein phosphorylation; IDA:UniProtKB.
88P87152    992   SPT7_SCHPO Transcriptional activator spt7 OS=...750.00000002     60.5     37     64GO:0000790; C:nuclear chromatin; IC:PomBase.::GO:0000124; C:SAGA complex; IDA:PomBase.
GO:0006338; P:chromatin remodeling; IC:PomBase.::GO:0016573; P:histone acetylation; ISS:PomBase.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006366; P:transcription from RNA polymerase II promoter; IC:PomBase.
89Q9LXA7    581   GTE2_ARATH Transcription factor GTE2 OS=Arabi...890.00000002     60.1     36     52GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0009294; P:DNA mediated transformation; IMP:TAIR.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
90Q99PP7    1142   TRI33_MOUSE E3 ubiquitin-protein ligase TRIM3...1740.00000002     60.1     30     47GO:0005634; C:nucleus; IDA:MGI.
GO:0070410; F:co-SMAD binding; ISS:BHF-UCL.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0070412; F:R-SMAD binding; ISS:BHF-UCL.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0030514; P:negative regulation of BMP signaling pathway; ISS:UniProtKB.::GO:0016567; P:protein ubiquitination; ISS:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0017015; P:regulation of transforming growth factor beta receptor signaling pathway; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
91Q9ULU4    1186   PKCB1_HUMAN Protein kinase C-binding protein ...800.00000006     58.9     36     56GO:0005634; C:nucleus; ISS:BHF-UCL.
GO:0070491; F:repressing transcription factor binding; ISS:BHF-UCL.::GO:0001106; F:RNA polymerase II transcription corepressor activity; ISS:BHF-UCL.::GO:0008270; F:zinc ion binding; IEA:InterPro.
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