Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YGR252W
Length:
439
Number of sequences:
5887
Description:
YGR252W GCN5 SGDID:S000003484, Chr VII from 996869-998188, Genome Release 64-1-1, Verified ORF, "Acetyltransferase, modifies N-terminal lysines on histones H2B and H3; acetylates Rsc4p, a subunit of the RSC chromatin-remodeling complex, altering replication stress tolerance; catalytic subunit of the ADA and SAGA histone acetyltransferase complexes; founding member of the Gcn5p-related N-acetyltransferase superfamily; mutant displays reduced transcription elongation in the G-less-based run-on (GLRO) assay"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
31Q9ULD4    1205   BRPF3_HUMAN Bromodomain and PHD finger-contai...900.00000000000003     79     43     61GO:0005829; C:cytosol; TAS:Reactome.::GO:0005576; C:extracellular region; TAS:Reactome.::GO:0070776; C:MOZ/MORF histone acetyltransferase complex; IDA:UniProtKB.
GO:0005515; F:protein binding; IPI:IntAct.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0043966; P:histone H3 acetylation; IDA:UniProtKB.::GO:0030168; P:platelet activation; TAS:Reactome.::GO:0002576; P:platelet degranulation; TAS:Reactome.
32Q8K2F0    726   BRD3_MOUSE Bromodomain-containing protein 3 O...1010.0000000000002     76.3     39     57GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
33Q4R8Y1    947   BRDT_MACFA Bromodomain testis-specific protei...860.0000000004     65.9     38     55GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
34Q9ESU6    1400   BRD4_MOUSE Bromodomain-containing protein 4 O...1000.0000000000001     77     41     62GO:0000794; C:condensed nuclear chromosome; IDA:MGI.::GO:0000790; C:nuclear chromatin; IDA:MGI.
GO:0003677; F:DNA binding; IDA:MGI.::GO:0005515; F:protein binding; IPI:MGI.
GO:0007059; P:chromosome segregation; IMP:MGI.::GO:0044154; P:histone H3-K14 acetylation; IMP:MGI.::GO:0043983; P:histone H4-K12 acetylation; IMP:MGI.::GO:0001833; P:inner cell mass cell proliferation; IMP:MGI.::GO:0043388; P:positive regulation of DNA binding; IDA:MGI.::GO:0006468; P:protein phosphorylation; IPI:MGI.
35O60885    1362   BRD4_HUMAN Bromodomain-containing protein 4 O...1000.0000000000004     75.5     40     62GO:0000794; C:condensed nuclear chromosome; IDA:MGI.::GO:0005737; C:cytoplasm; IDA:HPA.
GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW.::GO:0010971; P:positive regulation of G2/M transition of mitotic cell cycle; IMP:MGI.::GO:0032968; P:positive regulation of transcription elongation from RNA polymerase II promoter; IMP:MGI.::GO:0000114; P:regulation of transcription involved in G1 phase of mitotic cell cycle; IMP:MGI.
36Q15059    726   BRD3_HUMAN Bromodomain-containing protein 3 O...1010.0000000000002     76.3     39     57GO:0005634; C:nucleus; NAS:UniProtKB.
GO:0005515; F:protein binding; IPI:IntAct.
37A2BIL7    1536   BAZ1B_DANRE Tyrosine-protein kinase BAZ1B OS=...1370.0000000000001     77.4     34     55GO:0016585; C:chromatin remodeling complex; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003682; F:chromatin binding; ISS:UniProtKB.::GO:0070577; F:histone acetyl-lysine binding; ISS:UniProtKB.::GO:0035173; F:histone kinase activity; ISS:UniProtKB.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006974; P:response to DNA damage stimulus; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
38Q5TJG6    803   BRD2_CANFA Bromodomain-containing protein 2 O...970.0000000000004     75.1     38     56GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
39Q7JJ13    798   BRD2_MOUSE Bromodomain-containing protein 2 O...970.0000000000004     75.1     38     56GO:0005737; C:cytoplasm; IDA:MGI.::GO:0005634; C:nucleus; IDA:MGI.
40Q32S26    803   BRD2_BOVIN Bromodomain-containing protein 2 O...970.0000000000004     75.1     38     56GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
41Q6MGA9    798   BRD2_RAT Bromodomain-containing protein 2 OS=...970.0000000000004     75.1     38     56GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
42Q8UVR5    627   BAZ1A_XENLA Bromodomain adjacent to zinc fing...910.0000000000002     76.3     36     63GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
43P25440    801   BRD2_HUMAN Bromodomain-containing protein 2 O...970.0000000000005     74.7     38     56GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0004674; F:protein serine/threonine kinase activity; TAS:ProtInc.
GO:0007283; P:spermatogenesis; TAS:ProtInc.
44Q93ZB7    620   GTE11_ARATH Transcription factor GTE11 OS=Ara...1020.0000000000005     74.7     37     54GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0045893; P:positive regulation of transcription, DNA-dependent; IDA:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
45B2RWS6    2415   EP300_MOUSE Histone acetyltransferase p300 OS...830.0000000000006     74.7     40     66GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0000123; C:histone acetyltransferase complex; IEA:InterPro.::GO:0005667; C:transcription factor complex; IDA:UniProtKB.
GO:0003677; F:DNA binding; ISS:UniProtKB.::GO:0004402; F:histone acetyltransferase activity; ISS:UniProtKB.::GO:0003713; F:transcription coactivator activity; IMP:UniProtKB.::GO:0008134; F:transcription factor binding; IPI:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006915; P:apoptotic process; ISS:UniProtKB.::GO:0051216; P:cartilage development; NAS:UniProtKB.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0043967; P:histone H4 acetylation; ISS:UniProtKB.::GO:0018076; P:N-terminal peptidyl-lysine acetylation; ISS:UniProtKB.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0051091; P:positive regulation of sequence-specific DNA binding transcription factor activity; ISS:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.::GO:0043627; P:response to estrogen stimulus; ISS:UniProtKB.::GO:0001666; P:response to hypoxia; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
46Q09472    2414   EP300_HUMAN Histone acetyltransferase p300 OS...830.0000000000009     74.3     39     66GO:0005813; C:centrosome; IDA:HPA.
GO:0050681; F:androgen receptor binding; IPI:BHF-UCL.::GO:0008013; F:beta-catenin binding; IPI:BHF-UCL.::GO:0001047; F:core promoter binding; IDA:UniProtKB.::GO:0004402; F:histone acetyltransferase activity; IDA:UniProtKB.::GO:0001102; F:RNA polymerase II activating transcription factor binding; IPI:BHF-UCL.::GO:0003713; F:transcription coactivator activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006915; P:apoptotic process; IMP:UniProtKB.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0042771; P:DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis; IDA:UniProtKB.::GO:0043967; P:histone H4 acetylation; IMP:UniProtKB.::GO:0045087; P:innate immune response; TAS:Reactome.::GO:0018076; P:N-terminal peptidyl-lysine acetylation; IDA:UniProtKB.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.::GO:0007219; P:Notch signaling pathway; TAS:Reactome.::GO:0043923; P:positive regulation by host of viral transcription; IDA:BHF-UCL.::GO:0051091; P:positive regulation of sequence-specific DNA binding transcription factor activity; IDA:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.::GO:0060765; P:regulation of androgen receptor signaling pathway; IDA:BHF-UCL.::GO:0043627; P:response to estrogen stimulus; IDA:UniProtKB.::GO:0001666; P:response to hypoxia; IDA:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
47Q9HGP4    727   YK82_SCHPO Bromodomain-containing protein C63...990.00000000003     68.9     35     55GO:0005634; C:nucleus; IDA:PomBase.
GO:0006338; P:chromatin remodeling; ISS:PomBase.
48Q92793    2442   CBP_HUMAN CREB-binding protein OS=Homo sapien...830.000000000002     73.2     37     66GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0016604; C:nuclear body; IDA:UniProtKB.::GO:0000790; C:nuclear chromatin; IDA:BHF-UCL.
GO:0000987; F:core promoter proximal region sequence-specific DNA binding; IDA:BHF-UCL.::GO:0004402; F:histone acetyltransferase activity; IDA:UniProtKB.::GO:0043426; F:MRF binding; IDA:UniProtKB.::GO:0002039; F:p53 binding; IPI:UniProtKB.::GO:0001102; F:RNA polymerase II activating transcription factor binding; TAS:BHF-UCL.::GO:0001078; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription; IDA:BHF-UCL.::GO:0001105; F:RNA polymerase II transcription coactivator activity; TAS:BHF-UCL.::GO:0001191; F:RNA polymerase II transcription factor binding transcription factor activity involved in negative regulation of transcription; IDA:BHF-UCL.::GO:0004871; F:signal transducer activity; TAS:ProtInc.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0044255; P:cellular lipid metabolic process; TAS:Reactome.::GO:0042733; P:embryonic digit morphogenesis; TAS:BHF-UCL.::GO:0042592; P:homeostatic process; NAS:UniProtKB.::GO:0045087; P:innate immune response; TAS:Reactome.::GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW.::GO:0018076; P:N-terminal peptidyl-lysine acetylation; IDA:UniProtKB.::GO:0007219; P:Notch signaling pathway; TAS:Reactome.::GO:0006461; P:protein complex assembly; TAS:ProtInc.::GO:0008589; P:regulation of smoothened signaling pathway; TAS:BHF-UCL.::GO:0001666; P:response to hypoxia; TAS:UniProtKB.::GO:0044281; P:small molecule metabolic process; TAS:Reactome.::GO:0006367; P:transcription initiation from RNA polymerase II promoter; TAS:Reactome.
49Q6JHU9    2442   CBP_RAT CREB-binding protein OS=Rattus norveg...830.000000000002     73.2     37     66GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0000123; C:histone acetyltransferase complex; IEA:InterPro.::GO:0005667; C:transcription factor complex; IDA:RGD.
GO:0033613; F:activating transcription factor binding; IPI:RGD.::GO:0004402; F:histone acetyltransferase activity; ISS:UniProtKB.::GO:0043426; F:MRF binding; ISS:UniProtKB.::GO:0042975; F:peroxisome proliferator activated receptor binding; IDA:RGD.::GO:0046332; F:SMAD binding; IPI:RGD.::GO:0003713; F:transcription coactivator activity; TAS:RGD.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0008283; P:cell proliferation; IDA:RGD.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:RGD.::GO:0033261; P:regulation of S phase; IMP:RGD.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
50P45481    2441   CBP_MOUSE CREB-binding protein OS=Mus musculu...830.000000000002     73.2     37     66GO:0000940; C:condensed chromosome outer kinetochore; IDA:MGI.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0000123; C:histone acetyltransferase complex; IDA:MGI.::GO:0000790; C:nuclear chromatin; IDA:BHF-UCL.::GO:0005667; C:transcription factor complex; IDA:MGI.
GO:0003682; F:chromatin binding; IDA:MGI.::GO:0003677; F:DNA binding; IDA:MGI.::GO:0004402; F:histone acetyltransferase activity; ISS:UniProtKB.::GO:0043426; F:MRF binding; ISS:UniProtKB.::GO:0003713; F:transcription coactivator activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0030718; P:germ-line stem cell maintenance; IMP:MGI.::GO:0018076; P:N-terminal peptidyl-lysine acetylation; ISS:UniProtKB.::GO:0051091; P:positive regulation of sequence-specific DNA binding transcription factor activity; TAS:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IGI:MGI.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
51Q54UW4    1823   Y0777_DICDI Bromodomain-containing protein DD...900.000000000003     72.8     40     66
52Q80UV9    1891   TAF1_MOUSE Transcription initiation factor TF...970.0000009     55.1     29     49GO:0071339; C:MLL1 complex; ISS:UniProtKB.::GO:0045120; C:pronucleus; IDA:MGI.::GO:0005669; C:transcription factor TFIID complex; IEA:InterPro.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IDA:MGI.::GO:0004402; F:histone acetyltransferase activity; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006352; P:transcription initiation, DNA-dependent; IEA:InterPro.
53Q8H1D7    487   GTE5_ARATH Transcription factor GTE5, chlorop...920.000000000006     70.9     39     59GO:0009507; C:chloroplast; IEA:UniProtKB-SubCell.
GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
54Q9FGW9    1061   GTE10_ARATH Transcription factor GTE10 OS=Ara...1290.000000000006     71.6     31     47GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0009738; P:abscisic acid mediated signaling pathway; IEA:UniProtKB-KW.::GO:0051365; P:cellular response to potassium ion starvation; IEP:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0009409; P:response to cold; IEP:UniProtKB.::GO:0009651; P:response to salt stress; IEP:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
55Q60544    1865   TAF1_MESAU Transcription initiation factor TF...970.0000009     55.1     29     49GO:0071339; C:MLL1 complex; ISS:UniProtKB.::GO:0005669; C:transcription factor TFIID complex; IEA:InterPro.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0004402; F:histone acetyltransferase activity; ISS:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.
GO:0000080; P:G1 phase of mitotic cell cycle; IMP:BHF-UCL.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:BHF-UCL.::GO:0006352; P:transcription initiation, DNA-dependent; IEA:InterPro.
56P21675    1872   TAF1_HUMAN Transcription initiation factor TF...970.0000009     55.1     29     49GO:0071339; C:MLL1 complex; IDA:UniProtKB.::GO:0005669; C:transcription factor TFIID complex; IDA:BHF-UCL.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0070577; F:histone acetyl-lysine binding; IDA:BHF-UCL.::GO:0004402; F:histone acetyltransferase activity; IDA:UniProtKB.::GO:0002039; F:p53 binding; IPI:BHF-UCL.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.::GO:0043565; F:sequence-specific DNA binding; ISS:BHF-UCL.::GO:0017025; F:TBP-class protein binding; IPI:BHF-UCL.::GO:0003713; F:transcription coactivator activity; IDA:BHF-UCL.
GO:0000080; P:G1 phase of mitotic cell cycle; IGI:BHF-UCL.::GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW.::GO:0018105; P:peptidyl-serine phosphorylation; IDA:BHF-UCL.::GO:0018107; P:peptidyl-threonine phosphorylation; IDA:BHF-UCL.::GO:0032436; P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process; IDA:BHF-UCL.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:BHF-UCL.::GO:0060261; P:positive regulation of transcription initiation from RNA polymerase II promoter; ISS:BHF-UCL.::GO:0046777; P:protein autophosphorylation; TAS:UniProtKB.::GO:0000117; P:regulation of transcription involved in G2/M-phase of mitotic cell cycle; ISS:BHF-UCL.::GO:0006974; P:response to DNA damage stimulus; IC:BHF-UCL.::GO:0051123; P:RNA polymerase II transcriptional preinitiation complex assembly; ISS:BHF-UCL.::GO:0006368; P:transcription elongation from RNA polymerase II promoter; TAS:Reactome.::GO:0016032; P:viral reproduction; TAS:Reactome.
57Q9Z277    1479   BAZ1B_MOUSE Tyrosine-protein kinase BAZ1B OS=...1120.00000000002     70.1     30     53GO:0005721; C:centromeric heterochromatin; IDA:MGI.::GO:0000793; C:condensed chromosome; IDA:MGI.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003682; F:chromatin binding; ISS:UniProtKB.::GO:0070577; F:histone acetyl-lysine binding; ISS:UniProtKB.::GO:0035173; F:histone kinase activity; ISS:UniProtKB.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC.::GO:0071884; F:vitamin D receptor activator activity; IMP:BHF-UCL.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0048096; P:chromatin-mediated maintenance of transcription; IMP:BHF-UCL.::GO:0006302; P:double-strand break repair; IMP:BHF-UCL.::GO:0003007; P:heart morphogenesis; IMP:BHF-UCL.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
58Q54BA2    806   Y3800_DICDI Ankyrin repeat, bromo and BTB dom...820.00000000002     69.7     40     62
GO:0005524; F:ATP binding; ISS:dictyBase.::GO:0004672; F:protein kinase activity; ISS:dictyBase.
59Q07442    638   BDF2_YEAST Bromodomain-containing factor 2 OS...920.0000000002     66.6     36     57GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IC:SGD.
GO:0001047; F:core promoter binding; IDA:SGD.::GO:0070577; F:histone acetyl-lysine binding; IDA:SGD.::GO:0001094; F:TFIID-class transcription factor binding; IPI:SGD.
GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0031452; P:negative regulation of heterochromatin assembly; IMP:SGD.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0030435; P:sporulation resulting in formation of a cellular spore; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
60Q84XV2    386   GTE1_ARATH Transcription factor GTE1 OS=Arabi...880.00000000002     68.6     41     59GO:0005634; C:nucleus; IDA:TAIR.
GO:0010030; P:positive regulation of seed germination; IMP:TAIR.::GO:0045893; P:positive regulation of transcription, DNA-dependent; IMP:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
61Q8IZX4    1826   TAF1L_HUMAN Transcription initiation factor T...970.000003     53.5     29     48GO:0005669; C:transcription factor TFIID complex; IEA:InterPro.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0004402; F:histone acetyltransferase activity; ISS:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.::GO:0017025; F:TBP-class protein binding; IPI:UniProtKB.
GO:0007140; P:male meiosis; IEP:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; IDA:UniProtKB.::GO:0006357; P:regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.::GO:0006352; P:transcription initiation, DNA-dependent; IEA:InterPro.
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