Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YGR252W
Length:
439
Number of sequences:
5887
Description:
YGR252W GCN5 SGDID:S000003484, Chr VII from 996869-998188, Genome Release 64-1-1, Verified ORF, "Acetyltransferase, modifies N-terminal lysines on histones H2B and H3; acetylates Rsc4p, a subunit of the RSC chromatin-remodeling complex, altering replication stress tolerance; catalytic subunit of the ADA and SAGA histone acetyltransferase complexes; founding member of the Gcn5p-related N-acetyltransferase superfamily; mutant displays reduced transcription elongation in the G-less-based run-on (GLRO) assay"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
121A2AHJ4    1799   BRWD3_MOUSE Bromodomain and WD repeat-contain...1070.002     44.3     25     50
GO:0007010; P:cytoskeleton organization; ISS:UniProtKB.::GO:0008360; P:regulation of cell shape; ISS:UniProtKB.
122P51532    1647   SMCA4_HUMAN Transcription activator BRG1 OS=H...800.00007     49.3     26     61GO:0071565; C:nBAF complex; ISS:UniProtKB.::GO:0071564; C:npBAF complex; ISS:UniProtKB.::GO:0005634; C:nucleus; IEA:InterPro.::GO:0016514; C:SWI/SNF complex; IDA:UniProtKB.::GO:0071778; C:WINAC complex; IDA:BHF-UCL.
GO:0050681; F:androgen receptor binding; IPI:BHF-UCL.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:InterPro.::GO:0008094; F:DNA-dependent ATPase activity; IGI:BHF-UCL.::GO:0004386; F:helicase activity; TAS:ProtInc.::GO:0070577; F:histone acetyl-lysine binding; IDA:BHF-UCL.::GO:0002039; F:p53 binding; IPI:BHF-UCL.::GO:0047485; F:protein N-terminus binding; IPI:UniProtKB.::GO:0030957; F:Tat protein binding; IPI:BHF-UCL.::GO:0003713; F:transcription coactivator activity; IMP:BHF-UCL.::GO:0003714; F:transcription corepressor activity; IDA:UniProtKB.
GO:0006338; P:chromatin remodeling; IDA:BHF-UCL.::GO:0060766; P:negative regulation of androgen receptor signaling pathway; IMP:BHF-UCL.::GO:0030308; P:negative regulation of cell growth; IMP:BHF-UCL.::GO:0045749; P:negative regulation of S phase of mitotic cell cycle; TAS:BHF-UCL.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; TAS:BHF-UCL.::GO:0003407; P:neural retina development; IEP:BHF-UCL.::GO:0006337; P:nucleosome disassembly; IDA:BHF-UCL.::GO:0043923; P:positive regulation by host of viral transcription; IMP:BHF-UCL.::GO:0051091; P:positive regulation of sequence-specific DNA binding transcription factor activity; IDA:BHF-UCL.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:BHF-UCL.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:InterPro.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
123Q3TKT4    1613   SMCA4_MOUSE Transcription activator BRG1 OS=M...800.00007     48.9     26     61GO:0000792; C:heterochromatin; IDA:MGI.::GO:0071565; C:nBAF complex; IDA:UniProtKB.::GO:0071564; C:npBAF complex; IDA:UniProtKB.::GO:0005719; C:nuclear euchromatin; IDA:MGI.::GO:0005726; C:perichromatin fibrils; IDA:MGI.::GO:0005625; C:soluble fraction; IDA:MGI.::GO:0016514; C:SWI/SNF complex; IDA:MGI.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003682; F:chromatin binding; IDA:MGI.::GO:0004386; F:helicase activity; IEA:UniProtKB-KW.::GO:0000977; F:RNA polymerase II regulatory region sequence-specific DNA binding; IDA:MGI.::GO:0003714; F:transcription corepressor activity; ISS:UniProtKB.
GO:0035887; P:aortic smooth muscle cell differentiation; IMP:MGI.::GO:0001832; P:blastocyst growth; IMP:MGI.::GO:0001835; P:blastocyst hatching; IMP:MGI.::GO:0000902; P:cell morphogenesis; IMP:MGI.::GO:0006338; P:chromatin remodeling; IMP:MGI.::GO:0060318; P:definitive erythrocyte differentiation; IMP:MGI.::GO:0010424; P:DNA methylation on cytosine within a CG sequence; IMP:MGI.::GO:0035116; P:embryonic hindlimb morphogenesis; IMP:MGI.::GO:0048562; P:embryonic organ morphogenesis; IMP:MGI.::GO:0048730; P:epidermis morphogenesis; IMP:MGI.::GO:0030198; P:extracellular matrix organization; IMP:MGI.::GO:0030900; P:forebrain development; IMP:MGI.::GO:0007403; P:glial cell fate determination; IMP:MGI.::GO:0060347; P:heart trabecula formation; IGI:MGI.::GO:0030902; P:hindbrain development; IMP:MGI.::GO:0043966; P:histone H3 acetylation; IMP:MGI.::GO:0030216; P:keratinocyte differentiation; IMP:MGI.::GO:0001889; P:liver development; IMP:MGI.::GO:0006346; P:methylation-dependent chromatin silencing; IDA:MGI.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:MGI.::GO:0006334; P:nucleosome assembly; TAS:MGI.::GO:0043388; P:positive regulation of DNA binding; IGI:MGI.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:MGI.::GO:0019827; P:stem cell maintenance; IMP:MGI.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0001570; P:vasculogenesis; IMP:MGI.
124Q8K1P7    1613   SMCA4_RAT Transcription activator BRG1 OS=Rat...800.00007     48.9     26     61GO:0071565; C:nBAF complex; ISS:UniProtKB.::GO:0071564; C:npBAF complex; ISS:UniProtKB.::GO:0005625; C:soluble fraction; IDA:RGD.::GO:0016514; C:SWI/SNF complex; IDA:RGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:InterPro.::GO:0004386; F:helicase activity; IEA:UniProtKB-KW.::GO:0032403; F:protein complex binding; IDA:RGD.::GO:0003714; F:transcription corepressor activity; ISS:UniProtKB.
GO:0043044; P:ATP-dependent chromatin remodeling; IDA:RGD.::GO:0007399; P:nervous system development; IEA:UniProtKB-KW.::GO:0006337; P:nucleosome disassembly; IDA:RGD.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
125Q6DIC0    1577   SMCA2_MOUSE Probable global transcription act...800.00008     48.9     25     63GO:0071565; C:nBAF complex; IDA:UniProtKB.::GO:0071564; C:npBAF complex; IDA:UniProtKB.::GO:0016514; C:SWI/SNF complex; TAS:MGI.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004386; F:helicase activity; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0035887; P:aortic smooth muscle cell differentiation; IMP:MGI.::GO:0008285; P:negative regulation of cell proliferation; IMP:MGI.::GO:0007399; P:nervous system development; IEA:UniProtKB-KW.::GO:0006334; P:nucleosome assembly; TAS:MGI.
126P53236    928   RSC1_YEAST Chromatin structure-remodeling com...1050.007     42.7     30     49GO:0016586; C:RSC complex; IDA:UniProtKB.
GO:0003677; F:DNA binding; IEA:InterPro.
GO:0043044; P:ATP-dependent chromatin remodeling; IC:UniProtKB.::GO:0006303; P:double-strand break repair via nonhomologous end joining; IPI:SGD.::GO:0006337; P:nucleosome disassembly; IDA:SGD.::GO:0042173; P:regulation of sporulation resulting in formation of a cellular spore; IMP:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0030435; P:sporulation resulting in formation of a cellular spore; IEA:UniProtKB-KW.::GO:0006368; P:transcription elongation from RNA polymerase II promoter; IDA:SGD.
127F4IAE9    1210   Y1591_ARATH ATPase family AAA domain-containi...680.0002     47.8     29     56
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
128P25439    1638   BRM_DROME ATP-dependent helicase brm OS=Droso...740.0002     47.8     30     57GO:0035060; C:brahma complex; IDA:FlyBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016887; F:ATPase activity; ISS:FlyBase.::GO:0003677; F:DNA binding; IEA:InterPro.::GO:0004386; F:helicase activity; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0043044; P:ATP-dependent chromatin remodeling; IDA:FlyBase.::GO:0007409; P:axonogenesis; IMP:FlyBase.::GO:0070983; P:dendrite guidance; IMP:FlyBase.::GO:0035172; P:hemocyte proliferation; TAS:FlyBase.::GO:0007480; P:imaginal disc-derived leg morphogenesis; IGI:FlyBase.::GO:0008587; P:imaginal disc-derived wing margin morphogenesis; IMP:FlyBase.::GO:0008586; P:imaginal disc-derived wing vein morphogenesis; IMP:FlyBase.::GO:0007474; P:imaginal disc-derived wing vein specification; IMP:FlyBase.::GO:0007517; P:muscle organ development; IMP:FlyBase.::GO:0045749; P:negative regulation of S phase of mitotic cell cycle; IGI:FlyBase.::GO:0048477; P:oogenesis; TAS:FlyBase.::GO:0006911; P:phagocytosis, engulfment; IMP:FlyBase.::GO:0045742; P:positive regulation of epidermal growth factor receptor signaling pathway; IMP:FlyBase.::GO:0045893; P:positive regulation of transcription, DNA-dependent; IDA:FlyBase.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
129A8X0L9    1285   TBP7_CAEBR Tat-binding homolog 7 OS=Caenorhab...800.0002     47.4     30     53
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
130Q54MP8    2200   Y5837_DICDI Bromodomain and WD repeat-contain...1070.0002     47.4     29     53
131Q09948    542   RSC4_SCHPO Chromatin structure-remodeling com...610.013     41.6     34     54GO:0005829; C:cytosol; IDA:PomBase.::GO:0000790; C:nuclear chromatin; IC:PomBase.::GO:0016586; C:RSC complex; IDA:PomBase.
GO:0006338; P:chromatin remodeling; IC:PomBase.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IEP:PomBase.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEP:PomBase.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
132Q6RI45    1802   BRWD3_HUMAN Bromodomain and WD repeat-contain...1080.004     43.5     28     47
GO:0007010; P:cytoskeleton organization; IMP:UniProtKB.::GO:0008360; P:regulation of cell shape; IMP:UniProtKB.
133Q9NR48    2969   ASH1L_HUMAN Histone-lysine N-methyltransferas...850.0007     45.8     33     49GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.::GO:0005794; C:Golgi apparatus; IDA:HPA.::GO:0005634; C:nucleus; IDA:HPA.::GO:0005923; C:tight junction; TAS:ProtInc.
GO:0003677; F:DNA binding; IEA:InterPro.::GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:EC.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007267; P:cell-cell signaling; TAS:ProtInc.::GO:0006323; P:DNA packaging; TAS:ProtInc.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006366; P:transcription from RNA polymerase II promoter; TAS:ProtInc.
134Q55BK3    234   Y1118_DICDI Bromodomain-containing protein DD...520.0008     44.3     38     63
135Q99MY8    2958   ASH1L_MOUSE Histone-lysine N-methyltransferas...760.002     44.7     34     51GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005923; C:tight junction; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:InterPro.::GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:EC.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
136P32597    1359   STH1_YEAST Nuclear protein STH1/NPS1 OS=Sacch...910.002     44.3     27     52GO:0000775; C:chromosome, centromeric region; IDA:UniProtKB.::GO:0016586; C:RSC complex; IDA:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:InterPro.::GO:0008094; F:DNA-dependent ATPase activity; IDA:SGD.::GO:0004386; F:helicase activity; IDA:UniProtKB.::GO:0070577; F:histone acetyl-lysine binding; IDA:SGD.
GO:0043044; P:ATP-dependent chromatin remodeling; IDA:UniProtKB.::GO:0031055; P:chromatin remodeling at centromere; IMP:SGD.::GO:0007010; P:cytoskeleton organization; IGI:UniProtKB.::GO:0006302; P:double-strand break repair; IMP:SGD.::GO:0000086; P:G2/M transition of mitotic cell cycle; IMP:UniProtKB.::GO:0007126; P:meiosis; IMP:UniProtKB.::GO:0006337; P:nucleosome disassembly; IDA:SGD.::GO:0016584; P:nucleosome positioning; IMP:SGD.::GO:0006355; P:regulation of transcription, DNA-dependent; IMP:UniProtKB.::GO:0006368; P:transcription elongation from RNA polymerase II promoter; IDA:SGD.
137Q06488    889   RSC2_YEAST Chromatin structure-remodeling com...710.002     43.9     31     55GO:0016586; C:RSC complex; IDA:UniProtKB.
GO:0003677; F:DNA binding; IEA:InterPro.
GO:0043044; P:ATP-dependent chromatin remodeling; IDA:UniProtKB.::GO:0000724; P:double-strand break repair via homologous recombination; IMP:SGD.::GO:0006303; P:double-strand break repair via nonhomologous end joining; IPI:SGD.::GO:0006337; P:nucleosome disassembly; IDA:SGD.::GO:0006276; P:plasmid maintenance; IMP:UniProtKB.::GO:0042173; P:regulation of sporulation resulting in formation of a cellular spore; IMP:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0007062; P:sister chromatid cohesion; IMP:SGD.::GO:0030435; P:sporulation resulting in formation of a cellular spore; IEA:UniProtKB-KW.::GO:0006368; P:transcription elongation from RNA polymerase II promoter; IDA:SGD.
138P54816    1291   TBP7_CAEEL Tat-binding homolog 7 OS=Caenorhab...940.01     42     26     47
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0008406; P:gonad development; IMP:WormBase.::GO:0045132; P:meiotic chromosome segregation; IMP:WormBase.::GO:0031445; P:regulation of heterochromatin assembly; IMP:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
139Q54DH8    2310   TAF1_DICDI Transcription initiation factor TF...770.012     42     31     51GO:0005669; C:transcription factor TFIID complex; ISS:dictyBase.
GO:0005524; F:ATP binding; ISS:dictyBase.::GO:0004402; F:histone acetyltransferase activity; ISS:dictyBase.
GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:dictyBase.::GO:0006461; P:protein complex assembly; ISS:dictyBase.::GO:0006468; P:protein phosphorylation; ISS:dictyBase.::GO:0000114; P:regulation of transcription involved in G1 phase of mitotic cell cycle; ISS:dictyBase.
140C6KTD2    6753   HKNMT_PLAF7 Putative histone-lysine N-methylt...730.044     40     36     53
GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:EC.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
141Q13342    867   LY10_HUMAN Nuclear body protein SP140 OS=Homo...830.21     37.7     33     48GO:0005737; C:cytoplasm; IDA:HPA.::GO:0005635; C:nuclear envelope; TAS:ProtInc.::GO:0005730; C:nucleolus; IDA:HPA.::GO:0005654; C:nucleoplasm; TAS:ProtInc.::GO:0005634; C:nucleus; IEA:InterPro.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006952; P:defense response; TAS:ProtInc.
142Q9H930    580   LY10L_HUMAN Nuclear body protein SP140-like p...840.29     37.4     32     49GO:0005634; C:nucleus; IEA:InterPro.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
143P40903    467   ISP6_SCHPO Sexual differentiation process put...1690.96     35.4     26     40GO:0005619; C:ascospore wall; ISS:RefGenome.::GO:0000324; C:fungal-type vacuole; TAS:PomBase.::GO:0005794; C:Golgi apparatus; IDA:PomBase.
GO:0042802; F:identical protein binding; IEA:InterPro.::GO:0004252; F:serine-type endopeptidase activity; ISS:RefGenome.
GO:0006914; P:autophagy; IMP:PomBase.::GO:0006995; P:cellular response to nitrogen starvation; IMP:PomBase.::GO:0000747; P:conjugation with cellular fusion; IMP:PomBase.::GO:0043086; P:negative regulation of catalytic activity; IEA:InterPro.::GO:0051603; P:proteolysis involved in cellular protein catabolic process; IMP:PomBase.::GO:0051171; P:regulation of nitrogen compound metabolic process; IMP:PomBase.::GO:0006401; P:RNA catabolic process; IGI:PomBase.::GO:0007033; P:vacuole organization; IMP:PomBase.
144Q55FT8    729   Y7958_DICDI Bromo and FHA domain-containing p...675.8     33.1     28     46
GO:0005488; F:binding; IEA:InterPro.
145Q8R5C8    562   ZMY11_MOUSE Zinc finger MYND domain-containin...706.5     32.7     26     53GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
146Q15326    562   ZMY11_HUMAN Zinc finger MYND domain-containin...708.2     32.7     26     53GO:0005737; C:cytoplasm; IDA:HPA.::GO:0005634; C:nucleus; IDA:HPA.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0008283; P:cell proliferation; TAS:ProtInc.::GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW.::GO:2001237; P:negative regulation of extrinsic apoptotic signaling pathway; IMP:UniProtKB.::GO:0043124; P:negative regulation of I-kappaB kinase/NF-kappaB cascade; IMP:UniProtKB.::GO:0046329; P:negative regulation of JNK cascade; IMP:UniProtKB.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; TAS:ProtInc.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
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