Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YGR252W
Length:
439
Number of sequences:
5887
Description:
YGR252W GCN5 SGDID:S000003484, Chr VII from 996869-998188, Genome Release 64-1-1, Verified ORF, "Acetyltransferase, modifies N-terminal lysines on histones H2B and H3; acetylates Rsc4p, a subunit of the RSC chromatin-remodeling complex, altering replication stress tolerance; catalytic subunit of the ADA and SAGA histone acetyltransferase complexes; founding member of the Gcn5p-related N-acetyltransferase superfamily; mutant displays reduced transcription elongation in the G-less-based run-on (GLRO) assay"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
1Q03330    439   GCN5_YEAST Histone acetyltransferase GCN5 OS=...4390     912     100     100GO:0005671; C:Ada2/Gcn5/Ada3 transcription activator complex; IDA:SGD.::GO:0000775; C:chromosome, centromeric region; IDA:SGD.::GO:0000124; C:SAGA complex; IDA:SGD.::GO:0046695; C:SLIK (SAGA-like) complex; IDA:SGD.
GO:0010484; F:H3 histone acetyltransferase activity; IDA:SGD.::GO:0070577; F:histone acetyl-lysine binding; IDA:SGD.::GO:0003713; F:transcription coactivator activity; TAS:SGD.
GO:0032968; P:positive regulation of transcription elongation from RNA polymerase II promoter; IMP:SGD.::GO:0034401; P:regulation of transcription by chromatin organization; IMP:SGD.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
2Q6FTW5    546   GCN5_CANGA Histone acetyltransferase GCN5 OS=...3820     732     89     95GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0004402; F:histone acetyltransferase activity; IEA:EC.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
3Q6CXW4    516   GCN5_KLULA Histone acetyltransferase GCN5 OS=...4310     722     81     89GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0004402; F:histone acetyltransferase activity; IEA:EC.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
4Q756G9    452   GCN5_ASHGO Histone acetyltransferase GCN5 OS=...4330     717     79     88GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0004402; F:histone acetyltransferase activity; IEA:EC.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
5Q8WZM0    464   GCN5_YARLI Histone acetyltransferase GCN5 OS=...3660     627     78     90GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0004402; F:histone acetyltransferase activity; IEA:EC.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
6Q6BGW1    455   GCN5_DEBHA Histone acetyltransferase GCN5 OS=...3700     590     75     85GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0004402; F:histone acetyltransferase activity; IEA:EC.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
7Q9UUK2    454   GCN5_SCHPO Histone acetyltransferase gcn5 OS=...3741e-173     501     62     81GO:0000790; C:nuclear chromatin; IC:PomBase.::GO:0000124; C:SAGA complex; IDA:PomBase.
GO:0010484; F:H3 histone acetyltransferase activity; IDA:PomBase.
GO:0006338; P:chromatin remodeling; IGI:PomBase.::GO:0044154; P:histone H3-K14 acetylation; TAS:PomBase.::GO:0043971; P:histone H3-K18 acetylation; TAS:PomBase.::GO:0043972; P:histone H3-K23 acetylation; TAS:PomBase.::GO:0043970; P:histone H3-K9 acetylation; TAS:PomBase.::GO:0007131; P:reciprocal meiotic recombination; IMP:PomBase.::GO:0006357; P:regulation of transcription from RNA polymerase II promoter; IMP:PomBase.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
8Q338B9    511   GCN5_ORYSJ Histone acetyltransferase GCN5 OS=...3571e-109     339     48     66
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
9Q9AR19    568   GCN5_ARATH Histone acetyltransferase GCN5 OS=...3661e-108     338     47     64GO:0005634; C:nucleus; IDA:TAIR.
GO:0003677; F:DNA binding; IDA:TAIR.::GO:0010484; F:H3 histone acetyltransferase activity; IDA:TAIR.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0009908; P:flower development; IMP:TAIR.::GO:0045893; P:positive regulation of transcription, DNA-dependent; TAS:TAIR.::GO:0009416; P:response to light stimulus; IMP:TAIR.::GO:0010015; P:root morphogenesis; IMP:TAIR.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
10Q92831    832   KAT2B_HUMAN Histone acetyltransferase KAT2B O...3572e-93     306     47     64GO:0005671; C:Ada2/Gcn5/Ada3 transcription activator complex; IDA:BHF-UCL.::GO:0016585; C:chromatin remodeling complex; IDA:UniProtKB.::GO:0000125; C:PCAF complex; NAS:UniProtKB.
GO:0004861; F:cyclin-dependent protein kinase inhibitor activity; ISS:UniProtKB.::GO:0004402; F:histone acetyltransferase activity; IEA:EC.::GO:0042826; F:histone deacetylase binding; IPI:UniProtKB.::GO:0004468; F:lysine N-acetyltransferase activity; ISS:UniProtKB.::GO:0019901; F:protein kinase binding; ISS:UniProtKB.::GO:0003713; F:transcription coactivator activity; IDA:UniProtKB.::GO:0008134; F:transcription factor binding; IPI:UniProtKB.
GO:0007050; P:cell cycle arrest; TAS:ProtInc.::GO:0032869; P:cellular response to insulin stimulus; IDA:BHF-UCL.::GO:0006338; P:chromatin remodeling; NAS:UniProtKB.::GO:0043966; P:histone H3 acetylation; IDA:BHF-UCL.::GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW.::GO:0018076; P:N-terminal peptidyl-lysine acetylation; IDA:UniProtKB.::GO:0008285; P:negative regulation of cell proliferation; IDA:UniProtKB.::GO:0007219; P:Notch signaling pathway; TAS:Reactome.::GO:0006361; P:transcription initiation from RNA polymerase I promoter; TAS:Reactome.::GO:0006367; P:transcription initiation from RNA polymerase II promoter; TAS:Reactome.
11Q9JHD1    813   KAT2B_MOUSE Histone acetyltransferase KAT2B O...3661e-92     303     47     63GO:0031672; C:A band; IDA:MGI.::GO:0042641; C:actomyosin; IDA:MGI.::GO:0016585; C:chromatin remodeling complex; ISS:UniProtKB.::GO:0031674; C:I band; IDA:MGI.::GO:0000776; C:kinetochore; IDA:MGI.
GO:0004861; F:cyclin-dependent protein kinase inhibitor activity; IDA:UniProtKB.::GO:0004402; F:histone acetyltransferase activity; IDA:MGI.::GO:0004468; F:lysine N-acetyltransferase activity; IDA:UniProtKB.::GO:0019901; F:protein kinase binding; IPI:UniProtKB.::GO:0003713; F:transcription coactivator activity; IDA:MGI.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0045736; P:negative regulation of cyclin-dependent protein kinase activity; IDA:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IGI:MGI.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
12Q92830    837   KAT2A_HUMAN Histone acetyltransferase KAT2A O...3485e-91     299     46     64GO:0005671; C:Ada2/Gcn5/Ada3 transcription activator complex; IDA:BHF-UCL.::GO:0030914; C:STAGA complex; IDA:UniProtKB.::GO:0033276; C:transcription factor TFTC complex; IDA:UniProtKB.
GO:0010484; F:H3 histone acetyltransferase activity; IDA:BHF-UCL.::GO:0042826; F:histone deacetylase binding; IPI:UniProtKB.::GO:0003713; F:transcription coactivator activity; IDA:UniProtKB.
GO:0006338; P:chromatin remodeling; TAS:ProtInc.::GO:0016578; P:histone deubiquitination; IDA:UniProtKB.::GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW.::GO:0006357; P:regulation of transcription from RNA polymerase II promoter; TAS:ProtInc.::GO:0006366; P:transcription from RNA polymerase II promoter; TAS:ProtInc.
13Q9JHD2    830   KAT2A_MOUSE Histone acetyltransferase KAT2A O...3482e-90     298     46     64GO:0030914; C:STAGA complex; IDA:MGI.
GO:0003682; F:chromatin binding; IDA:MGI.::GO:0010484; F:H3 histone acetyltransferase activity; IDA:MGI.::GO:0043997; F:histone acetyltransferase activity (H4-K12 specific); IDA:MGI.
GO:0008283; P:cell proliferation; IMP:MGI.::GO:0044154; P:histone H3-K14 acetylation; IDA:MGI.::GO:0001701; P:in utero embryonic development; IMP:MGI.::GO:0022037; P:metencephalon development; IMP:MGI.::GO:0030901; P:midbrain development; IMP:MGI.::GO:0035264; P:multicellular organism growth; IMP:MGI.::GO:0001843; P:neural tube closure; IMP:MGI.::GO:0042981; P:regulation of apoptotic process; IMP:MGI.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0001756; P:somitogenesis; IMP:MGI.::GO:0021537; P:telencephalon development; IMP:MGI.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
14Q9W0T1    2669   NU301_DROME Nucleosome-remodeling factor subu...983e-26     116     51     71GO:0016589; C:NURF complex; IDA:FlyBase.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0016922; F:ligand-dependent nuclear receptor binding; IPI:FlyBase.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0048813; P:dendrite morphogenesis; IMP:FlyBase.::GO:0035076; P:ecdysone receptor-mediated signaling pathway; IGI:FlyBase.::GO:0030097; P:hemopoiesis; IMP:FlyBase.::GO:0007095; P:mitotic cell cycle G2/M transition DNA damage checkpoint; IGI:FlyBase.::GO:0042766; P:nucleosome mobilization; IDA:FlyBase.::GO:0045747; P:positive regulation of Notch signaling pathway; IMP:FlyBase.::GO:0035073; P:pupariation; IMP:FlyBase.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IDA:FlyBase.
15Q12830    3046   BPTF_HUMAN Nucleosome-remodeling factor subun...952e-22     104     45     67GO:0005737; C:cytoplasm; TAS:ProtInc.::GO:0016589; C:NURF complex; IDA:UniProtKB.
GO:0005515; F:protein binding; IPI:IntAct.::GO:0043565; F:sequence-specific DNA binding; IDA:HGNC.::GO:0008134; F:transcription factor binding; IDA:MGI.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007420; P:brain development; IMP:HGNC.::GO:0006338; P:chromatin remodeling; IDA:HGNC.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:MGI.::GO:0045893; P:positive regulation of transcription, DNA-dependent; IMP:HGNC.::GO:0006351; P:transcription, DNA-dependent; IMP:HGNC.
16Q9BXF3    1484   CECR2_HUMAN Cat eye syndrome critical region ...1552e-19     94.7     34     56
GO:0005515; F:protein binding; IPI:HGNC.
GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0000910; P:cytokinesis; NAS:UniProtKB.::GO:0007010; P:cytoskeleton organization; NAS:UniProtKB.::GO:0006309; P:DNA fragmentation involved in apoptotic nuclear change; TAS:HGNC.::GO:0016192; P:vesicle-mediated transport; NAS:UniProtKB.
17Q9DE13    2130   BAZ2B_CHICK Bromodomain adjacent to zinc fing...1091e-18     92.8     44     61GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
18Q9UIF8    2168   BAZ2B_HUMAN Bromodomain adjacent to zinc fing...1054e-18     91.3     43     62GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:BHF-UCL.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; NAS:BHF-UCL.::GO:0006351; P:transcription, DNA-dependent; NAS:BHF-UCL.
19B7ZS37    1698   BAZ2A_XENLA Bromodomain adjacent to zinc fing...953e-17     88.2     43     63GO:0005677; C:chromatin silencing complex; ISS:UniProtKB.::GO:0005730; C:nucleolus; ISS:UniProtKB.::GO:0033553; C:rDNA heterochromatin; ISS:UniProtKB.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0070577; F:histone acetyl-lysine binding; ISS:UniProtKB.::GO:0003723; F:RNA binding; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0000183; P:chromatin silencing at rDNA; ISS:UniProtKB.::GO:0006306; P:DNA methylation; ISS:UniProtKB.::GO:0016575; P:histone deacetylation; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
20O88379    1555   BAZ1A_MOUSE Bromodomain adjacent to zinc fing...1033e-16     85.1     40     64GO:0000228; C:nuclear chromosome; IDA:MGI.
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006338; P:chromatin remodeling; TAS:MGI.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
21Q9NRL2    1556   BAZ1A_HUMAN Bromodomain adjacent to zinc fing...1034e-16     85.1     40     64GO:0016590; C:ACF complex; TAS:BHF-UCL.::GO:0008623; C:chromatin accessibility complex; IDA:UniProtKB.
GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006338; P:chromatin remodeling; TAS:BHF-UCL.::GO:0006261; P:DNA-dependent DNA replication; IDA:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; NAS:BHF-UCL.::GO:0006351; P:transcription, DNA-dependent; NAS:BHF-UCL.
22Q91YE5    1889   BAZ2A_MOUSE Bromodomain adjacent to zinc fing...1315e-16     84.3     36     52GO:0005677; C:chromatin silencing complex; IDA:UniProtKB.::GO:0005730; C:nucleolus; IDA:UniProtKB.::GO:0033553; C:rDNA heterochromatin; IDA:UniProtKB.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0070577; F:histone acetyl-lysine binding; IDA:UniProtKB.::GO:0003723; F:RNA binding; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0000183; P:chromatin silencing at rDNA; IDA:UniProtKB.::GO:0006306; P:DNA methylation; IDA:UniProtKB.::GO:0016575; P:histone deacetylation; IDA:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
23P35817    686   BDF1_YEAST Bromodomain-containing factor 1 OS...860.000000007     61.6     38     56GO:0000812; C:Swr1 complex; IDA:SGD.
GO:0003682; F:chromatin binding; IDA:SGD.::GO:0001047; F:core promoter binding; IDA:SGD.::GO:0070577; F:histone acetyl-lysine binding; IDA:SGD.::GO:0001094; F:TFIID-class transcription factor binding; IDA:SGD.
GO:0006338; P:chromatin remodeling; IPI:SGD.::GO:0006281; P:DNA repair; IMP:SGD.::GO:0031452; P:negative regulation of heterochromatin assembly; IMP:SGD.::GO:1900051; P:positive regulation of histone exchange; IMP:SGD.::GO:0090054; P:regulation of chromatin silencing at silent mating-type cassette; IMP:SGD.::GO:0031938; P:regulation of chromatin silencing at telomere; IMP:SGD.::GO:0034401; P:regulation of transcription by chromatin organization; IMP:SGD.::GO:0009301; P:snRNA transcription; IMP:SGD.::GO:0030435; P:sporulation resulting in formation of a cellular spore; IEA:UniProtKB-KW.
24Q9UIF9    1905   BAZ2A_HUMAN Bromodomain adjacent to zinc fing...928e-16     84     42     62GO:0005677; C:chromatin silencing complex; ISS:UniProtKB.::GO:0005730; C:nucleolus; ISS:UniProtKB.::GO:0033553; C:rDNA heterochromatin; ISS:UniProtKB.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0070577; F:histone acetyl-lysine binding; ISS:UniProtKB.::GO:0016922; F:ligand-dependent nuclear receptor binding; NAS:BHF-UCL.::GO:0003723; F:RNA binding; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006338; P:chromatin remodeling; NAS:UniProtKB.::GO:0000183; P:chromatin silencing at rDNA; ISS:UniProtKB.::GO:0006306; P:DNA methylation; ISS:UniProtKB.::GO:0016575; P:histone deacetylation; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; NAS:UniProtKB.
25P51123    2129   TAF1_DROME Transcription initiation factor TF...820.000000004     62.8     37     57GO:0005669; C:transcription factor TFIID complex; IDA:FlyBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0035174; F:histone serine kinase activity; IDA:FlyBase.::GO:0043565; F:sequence-specific DNA binding; IDA:FlyBase.::GO:0001129; F:TBP-class protein binding RNA polymerase II transcription factor activity involved in preinitiation complex assembly; IPI:FlyBase.::GO:0008134; F:transcription factor binding; IPI:FlyBase.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0016573; P:histone acetylation; IDA:FlyBase.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:FlyBase.::GO:0060261; P:positive regulation of transcription initiation from RNA polymerase II promoter; IDA:BHF-UCL.::GO:0046425; P:regulation of JAK-STAT cascade; IMP:FlyBase.::GO:0000117; P:regulation of transcription involved in G2/M-phase of mitotic cell cycle; IMP:FlyBase.
26Q91Y44    956   BRDT_MOUSE Bromodomain testis-specific protei...870.000000002     63.5     36     56GO:0005634; C:nucleus; IDA:MGI.
GO:0042393; F:histone binding; IDA:MGI.
GO:0006338; P:chromatin remodeling; IDA:MGI.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
27Q9Y7N0    578   BDF1_SCHPO SWR1 complex bromodomain subunit b...970.00000000001     70.1     36     60GO:0000812; C:Swr1 complex; IDA:PomBase.
28O95696    1058   BRD1_HUMAN Bromodomain-containing protein 1 O...900.00000000000001     80.1     41     62GO:0070776; C:MOZ/MORF histone acetyltransferase complex; IDA:UniProtKB.
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0043966; P:histone H3 acetylation; IDA:UniProtKB.
29P13709    2038   FSH_DROME Homeotic protein female sterile OS=...1420.00000000001     71.2     31     49GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0045892; P:negative regulation of transcription, DNA-dependent; IMP:FlyBase.::GO:0007362; P:terminal region determination; IMP:FlyBase.
30Q58F21    947   BRDT_HUMAN Bromodomain testis-specific protei...860.000000004     62.4     37     53GO:0005634; C:nucleus; IDA:HPA.
GO:0004674; F:protein serine/threonine kinase activity; TAS:ProtInc.::GO:0003713; F:transcription coactivator activity; TAS:ProtInc.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
31Q9ULD4    1205   BRPF3_HUMAN Bromodomain and PHD finger-contai...900.00000000000003     79     43     61GO:0005829; C:cytosol; TAS:Reactome.::GO:0005576; C:extracellular region; TAS:Reactome.::GO:0070776; C:MOZ/MORF histone acetyltransferase complex; IDA:UniProtKB.
GO:0005515; F:protein binding; IPI:IntAct.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0043966; P:histone H3 acetylation; IDA:UniProtKB.::GO:0030168; P:platelet activation; TAS:Reactome.::GO:0002576; P:platelet degranulation; TAS:Reactome.
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