Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
Home About FGC Use Cases Species List

UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YGR232W
Length:
228
Number of sequences:
5887
Description:
YGR232W NAS6 SGDID:S000003464, Chr VII from 953960-954646, Genome Release 64-1-1, Verified ORF, "Proteasome-interacting protein involved in the assembly of the base subcomplex of the 19S proteasomal regulatory particle (RP); ortholog of human oncoprotein gankyrin, which interacts with the Rb tumor suppressor and CDK4/6"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
1P50086    228   PSD10_YEAST Probable 26S proteasome regulator...2281e-168     471     100     100GO:0005829; C:cytosol; IDA:SGD.::GO:0005634; C:nucleus; IDA:SGD.
GO:0005515; F:protein binding; IPI:IntAct.
GO:0070682; P:proteasome regulatory particle assembly; IMP:SGD.::GO:0006508; P:proteolysis; IPI:SGD.
2O75832    226   PSD10_HUMAN 26S proteasome non-ATPase regulat...1520.0000000002     62     33     49GO:0015629; C:actin cytoskeleton; IDA:HPA.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0045111; C:intermediate filament cytoskeleton; IDA:HPA.::GO:0005654; C:nucleoplasm; TAS:Reactome.::GO:0005838; C:proteasome regulatory particle; TAS:ProtInc.
GO:0008134; F:transcription factor binding; IPI:UniProtKB.
GO:0031145; P:anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; TAS:Reactome.::GO:0002479; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; TAS:Reactome.::GO:0006915; P:apoptotic process; TAS:Reactome.::GO:0007253; P:cytoplasmic sequestering of NF-kappaB; IDA:UniProtKB.::GO:0006977; P:DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest; TAS:Reactome.::GO:0000082; P:G1/S transition of mitotic cell cycle; TAS:Reactome.::GO:0010467; P:gene expression; TAS:Reactome.::GO:0000216; P:M/G1 transition of mitotic cell cycle; TAS:Reactome.::GO:0016071; P:mRNA metabolic process; TAS:Reactome.::GO:0043066; P:negative regulation of apoptotic process; IDA:UniProtKB.::GO:0043518; P:negative regulation of DNA damage response, signal transduction by p53 class mediator; IDA:UniProtKB.::GO:0043409; P:negative regulation of MAPK cascade; IMP:UniProtKB.::GO:0032088; P:negative regulation of NF-kappaB transcription factor activity; IDA:UniProtKB.::GO:0090201; P:negative regulation of release of cytochrome c from mitochondria; IMP:UniProtKB.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.::GO:0051436; P:negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.::GO:0030307; P:positive regulation of cell growth; IDA:UniProtKB.::GO:0045737; P:positive regulation of cyclin-dependent protein kinase activity; IDA:UniProtKB.::GO:0032436; P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process; IDA:UniProtKB.::GO:0051437; P:positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.::GO:0070682; P:proteasome regulatory particle assembly; IMP:UniProtKB.::GO:0000209; P:protein polyubiquitination; TAS:Reactome.::GO:0006521; P:regulation of cellular amino acid metabolic process; TAS:Reactome.::GO:0000084; P:S phase of mitotic cell cycle; TAS:Reactome.::GO:0044281; P:small molecule metabolic process; TAS:Reactome.::GO:0016032; P:viral reproduction; TAS:Reactome.
3Q9Z2X3    231   PSD10_RAT 26S proteasome non-ATPase regulator...1520.000000007     57.4     33     48GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0007253; P:cytoplasmic sequestering of NF-kappaB; ISS:UniProtKB.::GO:0043066; P:negative regulation of apoptotic process; ISS:UniProtKB.::GO:0043518; P:negative regulation of DNA damage response, signal transduction by p53 class mediator; ISS:UniProtKB.::GO:0043409; P:negative regulation of MAPK cascade; ISS:UniProtKB.::GO:0032088; P:negative regulation of NF-kappaB transcription factor activity; ISS:UniProtKB.::GO:0090201; P:negative regulation of release of cytochrome c from mitochondria; ISS:UniProtKB.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0030307; P:positive regulation of cell growth; ISS:UniProtKB.::GO:0045737; P:positive regulation of cyclin-dependent protein kinase activity; ISS:UniProtKB.::GO:0032436; P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process; ISS:UniProtKB.::GO:0031398; P:positive regulation of protein ubiquitination; ISS:UniProtKB.::GO:0070682; P:proteasome regulatory particle assembly; ISS:UniProtKB.
4Q9Z2X2    231   PSD10_MOUSE 26S proteasome non-ATPase regulat...1520.00000000002     64.7     35     49GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0007253; P:cytoplasmic sequestering of NF-kappaB; ISS:UniProtKB.::GO:0043066; P:negative regulation of apoptotic process; ISS:UniProtKB.::GO:0043518; P:negative regulation of DNA damage response, signal transduction by p53 class mediator; ISS:UniProtKB.::GO:0043409; P:negative regulation of MAPK cascade; ISS:UniProtKB.::GO:0032088; P:negative regulation of NF-kappaB transcription factor activity; ISS:UniProtKB.::GO:0090201; P:negative regulation of release of cytochrome c from mitochondria; ISS:UniProtKB.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0030307; P:positive regulation of cell growth; ISS:UniProtKB.::GO:0045737; P:positive regulation of cyclin-dependent protein kinase activity; ISS:UniProtKB.::GO:0032436; P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process; ISS:UniProtKB.::GO:0031398; P:positive regulation of protein ubiquitination; ISS:UniProtKB.::GO:0070682; P:proteasome regulatory particle assembly; ISS:UniProtKB.
5Q10311    234   YD58_SCHPO Ankyrin repeat-containing protein ...820.0002     44.7     30     50GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.::GO:0005838; C:proteasome regulatory particle; ISS:PomBase.
GO:0043161; P:proteasomal ubiquitin-dependent protein catabolic process; NAS:PomBase.
6Q54HW1    232   PSD10_DICDI 26S proteasome non-ATPase regulat...2218e-21     91.7     32     48
7Q9J5H8    434   V023_FOWPN Putative ankyrin repeat protein FP...1978e-19     87.8     33     51
8Q12955    4377   ANK3_HUMAN Ankyrin-3 OS=Homo sapiens (Human)....1970.000008     50.1     30     44GO:0016323; C:basolateral plasma membrane; IDA:UniProtKB.::GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.
GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0045184; P:establishment of protein localization; IMP:UniProtKB.::GO:0007165; P:signal transduction; IEA:InterPro.
9P16157    1881   ANK1_HUMAN Ankyrin-1 OS=Homo sapiens (Human)....1840.000004     50.8     27     44GO:0016323; C:basolateral plasma membrane; NAS:UniProtKB.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0031430; C:M band; IEA:UniProtKB-SubCell.::GO:0016529; C:sarcoplasmic reticulum; IEA:UniProtKB-SubCell.::GO:0014731; C:spectrin-associated cytoskeleton; IDA:BHF-UCL.
GO:0008093; F:cytoskeletal adaptor activity; TAS:UniProtKB.::GO:0019899; F:enzyme binding; IPI:UniProtKB.::GO:0030507; F:spectrin binding; NAS:UniProtKB.::GO:0005200; F:structural constituent of cytoskeleton; TAS:ProtInc.
GO:0007411; P:axon guidance; TAS:Reactome.::GO:0007010; P:cytoskeleton organization; NAS:UniProtKB.::GO:0006887; P:exocytosis; NAS:UniProtKB.::GO:0045199; P:maintenance of epithelial cell apical/basal polarity; TAS:UniProtKB.::GO:0007165; P:signal transduction; IEA:InterPro.
10Q6PFX9    1320   TNKS1_MOUSE Tankyrase-1 OS=Mus musculus (Mous...2160.00006     47     25     40GO:0000775; C:chromosome, centromeric region; IEA:UniProtKB-SubCell.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0005643; C:nuclear pore; IEA:UniProtKB-SubCell.
GO:0003950; F:NAD+ ADP-ribosyltransferase activity; ISS:UniProtKB.
GO:0051028; P:mRNA transport; IEA:UniProtKB-KW.::GO:0090263; P:positive regulation of canonical Wnt receptor signaling pathway; ISS:UniProtKB.::GO:0070213; P:protein auto-ADP-ribosylation; ISS:UniProtKB.::GO:0000209; P:protein polyubiquitination; ISS:UniProtKB.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
11O95271    1327   TNKS1_HUMAN Tankyrase-1 OS=Homo sapiens (Huma...2160.00006     47.4     25     40GO:0000775; C:chromosome, centromeric region; IEA:UniProtKB-SubCell.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IDA:BHF-UCL.::GO:0000784; C:nuclear chromosome, telomeric region; IDA:BHF-UCL.::GO:0031965; C:nuclear membrane; TAS:BHF-UCL.::GO:0005643; C:nuclear pore; TAS:BHF-UCL.::GO:0000242; C:pericentriolar material; TAS:BHF-UCL.
GO:0003950; F:NAD+ ADP-ribosyltransferase activity; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0008270; F:zinc ion binding; IDA:BHF-UCL.
GO:0007052; P:mitotic spindle organization; TAS:BHF-UCL.::GO:0051028; P:mRNA transport; IEA:UniProtKB-KW.::GO:0043392; P:negative regulation of DNA binding; IDA:BHF-UCL.::GO:0018105; P:peptidyl-serine phosphorylation; IDA:MGI.::GO:0018107; P:peptidyl-threonine phosphorylation; IDA:MGI.::GO:0090263; P:positive regulation of canonical Wnt receptor signaling pathway; IMP:UniProtKB.::GO:0032212; P:positive regulation of telomere maintenance via telomerase; IDA:BHF-UCL.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.::GO:0070213; P:protein auto-ADP-ribosylation; IDA:UniProtKB.::GO:0070198; P:protein localization to chromosome, telomeric region; IMP:BHF-UCL.::GO:0070212; P:protein poly-ADP-ribosylation; IDA:BHF-UCL.::GO:0000209; P:protein polyubiquitination; IDA:UniProtKB.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0051225; P:spindle assembly; TAS:BHF-UCL.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
12Q5ZLC8    1073   ANR52_CHICK Serine/threonine-protein phosphat...2340.000009     49.7     25     38
13Q02357    1862   ANK1_MOUSE Ankyrin-1 OS=Mus musculus (Mouse)....1450.0008     43.9     29     44GO:0030863; C:cortical cytoskeleton; IDA:MGI.::GO:0016020; C:membrane; IDA:MGI.::GO:0016529; C:sarcoplasmic reticulum; IEA:UniProtKB-SubCell.::GO:0014731; C:spectrin-associated cytoskeleton; IMP:MGI.
GO:0048821; P:erythrocyte development; IMP:MGI.::GO:0015672; P:monovalent inorganic cation transport; IMP:MGI.::GO:0006779; P:porphyrin-containing compound biosynthetic process; IMP:MGI.::GO:0007165; P:signal transduction; IEA:InterPro.
14Q8Q0U0    360   Y045_METMA Putative ankyrin repeat protein MM...1370.09     37     31     48
15Q9Z148    1263   EHMT2_MOUSE Histone-lysine N-methyltransferas...2150.00003     48.5     27     40GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IDA:UniProtKB.
GO:0046976; F:histone methyltransferase activity (H3-K27 specific); IDA:UniProtKB.::GO:0046974; F:histone methyltransferase activity (H3-K9 specific); IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0010424; P:DNA methylation on cytosine within a CG sequence; IMP:MGI.::GO:0009566; P:fertilization; IMP:MGI.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IMP:MGI.::GO:0035265; P:organ growth; IMP:MGI.::GO:0000239; P:pachytene; IMP:MGI.::GO:0018027; P:peptidyl-lysine dimethylation; ISS:UniProtKB.::GO:0007286; P:spermatid development; IMP:MGI.::GO:0007130; P:synaptonemal complex assembly; IMP:MGI.
16Q502K3    1071   ANR52_DANRE Serine/threonine-protein phosphat...1840.000002     51.6     28     42
17Q96KQ7    1210   EHMT2_HUMAN Histone-lysine N-methyltransferas...2150.000002     51.6     27     40GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0046976; F:histone methyltransferase activity (H3-K27 specific); ISS:UniProtKB.::GO:0046974; F:histone methyltransferase activity (H3-K9 specific); ISS:UniProtKB.::GO:0002039; F:p53 binding; IPI:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006306; P:DNA methylation; ISS:UniProtKB.::GO:0018027; P:peptidyl-lysine dimethylation; IDA:UniProtKB.
18Q8NB46    1076   ANR52_HUMAN Serine/threonine-protein phosphat...1724.4     32     23     35
19Q54KA7    986   SECG_DICDI Ankyrin repeat, PH and SEC7 domain...1950.00000000008     64.7     28     42GO:0005829; C:cytosol; IDA:dictyBase.::GO:0005764; C:lysosome; IDA:dictyBase.
GO:0005086; F:ARF guanyl-nucleotide exchange factor activity; IEA:InterPro.::GO:0005543; F:phospholipid binding; IEA:InterPro.
GO:0031589; P:cell-substrate adhesion; IMP:dictyBase.::GO:0006935; P:chemotaxis; IMP:dictyBase.::GO:0032012; P:regulation of ARF protein signal transduction; IEA:InterPro.
20B2RXR6    993   ANR44_MOUSE Serine/threonine-protein phosphat...740.37     35.4     31     53
21Q29RM5    653   FEM1A_BOVIN Protein fem-1 homolog A OS=Bos ta...1480.000003     51.2     29     45GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005488; F:binding; IEA:InterPro.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.
GO:0051438; P:regulation of ubiquitin-protein ligase activity; ISS:UniProtKB.
22O15084    1053   ANR28_HUMAN Serine/threonine-protein phosphat...910.62     34.7     29     47GO:0005654; C:nucleoplasm; IEA:UniProtKB-SubCell.
GO:0005515; F:protein binding; IPI:IntAct.
23Q9BSK4    669   FEM1A_HUMAN Protein fem-1 homolog A OS=Homo s...1470.000002     51.6     29     46GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0031867; F:EP4 subtype prostaglandin E2 receptor binding; IPI:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.
GO:0050728; P:negative regulation of inflammatory response; IDA:UniProtKB.::GO:0051438; P:regulation of ubiquitin-protein ligase activity; ISS:UniProtKB.
24Q505D1    1053   ANR28_MOUSE Serine/threonine-protein phosphat...1980.00000001     58.2     26     42GO:0005654; C:nucleoplasm; IEA:UniProtKB-SubCell.
25Q8N8A2    993   ANR44_HUMAN Serine/threonine-protein phosphat...741.2     33.9     30     53
GO:0005515; F:protein binding; IPI:IntAct.
26Q54F46    803   WARA_DICDI Homeobox protein Wariai OS=Dictyos...1650.0006     44.3     26     39GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
GO:0009653; P:anatomical structure morphogenesis; IMP:dictyBase.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0045595; P:regulation of cell differentiation; IMP:dictyBase.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
27Q9H2K2    1166   TNKS2_HUMAN Tankyrase-2 OS=Homo sapiens (Huma...1280.002     42.4     34     48GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IDA:BHF-UCL.::GO:0000784; C:nuclear chromosome, telomeric region; IC:BHF-UCL.::GO:0005635; C:nuclear envelope; IDA:BHF-UCL.::GO:0000242; C:pericentriolar material; IDA:BHF-UCL.::GO:0048471; C:perinuclear region of cytoplasm; IDA:BHF-UCL.
GO:0019899; F:enzyme binding; IPI:UniProtKB.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0003950; F:NAD+ ADP-ribosyltransferase activity; IDA:UniProtKB.
GO:0090263; P:positive regulation of canonical Wnt receptor signaling pathway; IMP:UniProtKB.::GO:0032212; P:positive regulation of telomere maintenance via telomerase; IC:BHF-UCL.::GO:0070213; P:protein auto-ADP-ribosylation; IDA:UniProtKB.::GO:0070198; P:protein localization to chromosome, telomeric region; IMP:BHF-UCL.::GO:0000209; P:protein polyubiquitination; IDA:UniProtKB.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
28Q3UES3    1166   TNKS2_MOUSE Tankyrase-2 OS=Mus musculus (Mous...1280.008     40.8     32     45GO:0000781; C:chromosome, telomeric region; IEA:UniProtKB-SubCell.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0003950; F:NAD+ ADP-ribosyltransferase activity; ISS:UniProtKB.
GO:0035264; P:multicellular organism growth; IMP:MGI.::GO:0090263; P:positive regulation of canonical Wnt receptor signaling pathway; ISS:UniProtKB.::GO:0070213; P:protein auto-ADP-ribosylation; ISS:UniProtKB.::GO:0000209; P:protein polyubiquitination; ISS:UniProtKB.::GO:0040014; P:regulation of multicellular organism growth; IMP:MGI.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
29Q8C8R3    3898   ANK2_MOUSE Ankyrin-2 OS=Mus musculus (Mouse)....2190.002     42.7     27     39GO:0016324; C:apical plasma membrane; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005887; C:integral to plasma membrane; IDA:UniProtKB.::GO:0031430; C:M band; IEA:UniProtKB-SubCell.
GO:0005515; F:protein binding; IPI:MGI.
GO:0060048; P:cardiac muscle contraction; IMP:MGI.::GO:0034394; P:protein localization at cell surface; IMP:UniProtKB.::GO:0007165; P:signal transduction; IEA:InterPro.
30Q01484    3957   ANK2_HUMAN Ankyrin-2 OS=Homo sapiens (Human)....2190.002     42.4     27     39GO:0016324; C:apical plasma membrane; IEA:UniProtKB-SubCell.::GO:0016323; C:basolateral plasma membrane; IDA:UniProtKB.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0031430; C:M band; IEA:UniProtKB-SubCell.
GO:0019899; F:enzyme binding; IPI:UniProtKB.
GO:0007411; P:axon guidance; TAS:Reactome.::GO:0007165; P:signal transduction; IEA:InterPro.
31Q9ERK0    786   RIPK4_MOUSE Receptor-interacting serine/threo...643.3     32.3     30     59GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW.
records
Previous ‹‹ ›› Next Total records: 846 1 - 30
Elimate unknown annotation:
Filter for keyword on hit description:
Select upper E value:
Select lower bit score:
Select lower %idenity value:
Select lower %positive value:
Taxonomic division:
Lower limit on hit length:
Lower limit on alignment length::