Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YGR232W
Length:
228
Number of sequences:
5887
Description:
YGR232W NAS6 SGDID:S000003464, Chr VII from 953960-954646, Genome Release 64-1-1, Verified ORF, "Proteasome-interacting protein involved in the assembly of the base subcomplex of the 19S proteasomal regulatory particle (RP); ortholog of human oncoprotein gankyrin, which interacts with the Rb tumor suppressor and CDK4/6"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
91Q5R5V4    452   ILK_PONAB Integrin-linked protein kinase OS=P...1360.0001     46.2     29     46GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0009966; P:regulation of signal transduction; IEA:InterPro.
92Q13418    452   ILK_HUMAN Integrin-linked protein kinase OS=H...1360.0001     46.2     29     46GO:0005829; C:cytosol; TAS:Reactome.::GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; NAS:UniProtKB.::GO:0019901; F:protein kinase binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
GO:0034329; P:cell junction assembly; TAS:Reactome.::GO:0008283; P:cell proliferation; NAS:UniProtKB.::GO:0007160; P:cell-matrix adhesion; NAS:UniProtKB.::GO:0007229; P:integrin-mediated signaling pathway; NAS:UniProtKB.::GO:0090263; P:positive regulation of canonical Wnt receptor signaling pathway; IMP:UniProtKB.::GO:0042327; P:positive regulation of phosphorylation; IMP:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; IMP:UniProtKB.::GO:0034446; P:substrate adhesion-dependent cell spreading; IMP:UniProtKB.
93Q3SWY2    452   ILK_BOVIN Integrin-linked protein kinase OS=B...1360.0001     46.2     29     46GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0009966; P:regulation of signal transduction; IEA:InterPro.
94G0LXV8    1351   LATA_LATHA Alpha-latrotoxin-Lh1a OS=Latrodect...840.24     36.2     31     52GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0072556; C:other organism presynaptic membrane; IEA:UniProtKB-KW.
GO:0006887; P:exocytosis; IEA:UniProtKB-KW.
95B1AK53    854   ESPN_HUMAN Espin OS=Homo sapiens (Human). GN=...1460.29     35.8     27     39GO:0005903; C:brush border; ISS:UniProtKB.::GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0031941; C:filamentous actin; ISS:UniProtKB.::GO:0032420; C:stereocilium; IEA:UniProtKB-SubCell.
GO:0051015; F:actin filament binding; ISS:UniProtKB.::GO:0017124; F:SH3 domain binding; ISS:UniProtKB.
GO:0007605; P:sensory perception of sound; IEA:UniProtKB-KW.
96Q6AWW5    524   Y5262_ARATH Ankyrin repeat-containing protein...1770.061     37.7     24     38GO:0005783; C:endoplasmic reticulum; IDA:TAIR.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IDA:TAIR.
97Q8UVC1    1021   INVS_DANRE Inversin OS=Danio rerio (Zebrafish...1464.4     32     27     40GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.
GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.
GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
98Q91974    318   IKBA_CHICK NF-kappa-B inhibitor alpha OS=Gall...864.2     32     26     45GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0035419; P:activation of MAPK activity involved in innate immune response; TAS:Reactome.::GO:0007250; P:activation of NF-kappaB-inducing kinase activity; TAS:Reactome.::GO:0002755; P:MyD88-dependent toll-like receptor signaling pathway; TAS:Reactome.::GO:0048145; P:regulation of fibroblast proliferation; NAS:UniProtKB.::GO:0035681; P:toll-like receptor 15 signaling pathway; TAS:Reactome.::GO:0034134; P:toll-like receptor 2 signaling pathway; TAS:Reactome.::GO:0035682; P:toll-like receptor 21 signaling pathway; TAS:Reactome.::GO:0034138; P:toll-like receptor 3 signaling pathway; TAS:Reactome.::GO:0034142; P:toll-like receptor 4 signaling pathway; TAS:Reactome.::GO:0034146; P:toll-like receptor 5 signaling pathway; TAS:Reactome.::GO:0034154; P:toll-like receptor 7 signaling pathway; TAS:Reactome.
99O60733    806   PA2G6_HUMAN 85 kDa calcium-independent phosph...1820.025     39.3     24     39GO:0005813; C:centrosome; IDA:HPA.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
GO:0032049; P:cardiolipin biosynthetic process; IMP:UniProtKB.::GO:0008219; P:cell death; IEA:UniProtKB-KW.::GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.
100P25963    317   IKBA_HUMAN NF-kappa-B inhibitor alpha OS=Homo...606.4     31.2     33     47GO:0005829; C:cytosol; TAS:Reactome.::GO:0033256; C:I-kappaB/NF-kappaB complex; TAS:BHF-UCL.::GO:0005634; C:nucleus; IDA:UniProtKB.::GO:0005886; C:plasma membrane; IDA:HPA.
GO:0042802; F:identical protein binding; IPI:IntAct.::GO:0051059; F:NF-kappaB binding; IPI:UniProtKB.::GO:0008139; F:nuclear localization sequence binding; IPI:UniProtKB.::GO:0031625; F:ubiquitin protein ligase binding; IPI:UniProtKB.
GO:0006916; P:anti-apoptosis; TAS:Reactome.::GO:0006915; P:apoptotic process; TAS:ProtInc.::GO:0070417; P:cellular response to cold; NAS:BHF-UCL.::GO:0007253; P:cytoplasmic sequestering of NF-kappaB; IMP:BHF-UCL.::GO:0045087; P:innate immune response; TAS:Reactome.::GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW.::GO:0002755; P:MyD88-dependent toll-like receptor signaling pathway; TAS:Reactome.::GO:0043392; P:negative regulation of DNA binding; NAS:UniProtKB.::GO:0010888; P:negative regulation of lipid storage; IMP:BHF-UCL.::GO:0010745; P:negative regulation of macrophage derived foam cell differentiation; IMP:BHF-UCL.::GO:0032088; P:negative regulation of NF-kappaB transcription factor activity; IDA:MGI.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0032270; P:positive regulation of cellular protein metabolic process; IMP:BHF-UCL.::GO:0010875; P:positive regulation of cholesterol efflux; IMP:BHF-UCL.::GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; TAS:Reactome.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.::GO:0032481; P:positive regulation of type I interferon production; TAS:Reactome.::GO:0050852; P:T cell receptor signaling pathway; TAS:Reactome.::GO:0008063; P:Toll signaling pathway; TAS:Reactome.::GO:0034130; P:toll-like receptor 1 signaling pathway; TAS:Reactome.::GO:0034134; P:toll-like receptor 2 signaling pathway; TAS:Reactome.::GO:0034138; P:toll-like receptor 3 signaling pathway; TAS:Reactome.::GO:0034142; P:toll-like receptor 4 signaling pathway; TAS:Reactome.::GO:0035666; P:TRIF-dependent toll-like receptor signaling pathway; TAS:Reactome.
101Q99728    777   BARD1_HUMAN BRCA1-associated RING domain prot...882.2     33.1     32     49GO:0070531; C:BRCA1-A complex; IDA:UniProtKB.::GO:0031436; C:BRCA1-BARD1 complex; IDA:UniProtKB.::GO:0005737; C:cytoplasm; IDA:UniProtKB.
GO:0019900; F:kinase binding; NAS:UniProtKB.::GO:0046982; F:protein heterodimerization activity; IPI:UniProtKB.::GO:0042803; F:protein homodimerization activity; IPI:UniProtKB.::GO:0003723; F:RNA binding; IDA:MGI.::GO:0004842; F:ubiquitin-protein ligase activity; NAS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007050; P:cell cycle arrest; NAS:UniProtKB.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0043066; P:negative regulation of apoptotic process; IMP:UniProtKB.::GO:0031441; P:negative regulation of mRNA 3'-end processing; NAS:UniProtKB.::GO:0046826; P:negative regulation of protein export from nucleus; IDA:UniProtKB.::GO:0043065; P:positive regulation of apoptotic process; IMP:UniProtKB.::GO:0045732; P:positive regulation of protein catabolic process; NAS:UniProtKB.::GO:0085020; P:protein K6-linked ubiquitination; IDA:UniProtKB.::GO:0042325; P:regulation of phosphorylation; IMP:UniProtKB.::GO:0001894; P:tissue homeostasis; TAS:UniProtKB.
102Q5UPV1    728   YL271_MIMIV Putative ankyrin repeat protein L...625.8     31.6     29     55
GO:0006520; P:cellular amino acid metabolic process; IEA:InterPro.
103Q05753    435   AKRP_ARATH Ankyrin repeat domain-containing p...1430.00007     47     30     46GO:0009507; C:chloroplast; IDA:TAIR.
GO:0005515; F:protein binding; IPI:IntAct.
104Q8VHS6    583   ASB15_MOUSE Ankyrin repeat and SOCS box prote...1930.007     40.8     23     39
GO:0035556; P:intracellular signal transduction; IEA:InterPro.
105Q3KP44    613   ANR55_HUMAN Ankyrin repeat domain-containing ...1990.00000002     57     28     43
106Q5ZIJ9    954   MIB2_CHICK E3 ubiquitin-protein ligase MIB2 O...1790.6     34.7     21     46GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004842; F:ubiquitin-protein ligase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007219; P:Notch signaling pathway; IEA:UniProtKB-KW.
107Q6F6B3    1849   TANC1_RAT Protein TANC1 OS=Rattus norvegicus ...860.56     35     31     49GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.::GO:0014069; C:postsynaptic density; IEA:UniProtKB-SubCell.::GO:0045211; C:postsynaptic membrane; IEA:UniProtKB-KW.
GO:0005515; F:protein binding; IPI:IntAct.
108Q99466    2003   NOTC4_HUMAN Neurogenic locus notch homolog pr...1590.05     38.1     27     42GO:0009986; C:cell surface; IDA:UniProtKB.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0005789; C:endoplasmic reticulum membrane; TAS:Reactome.::GO:0005576; C:extracellular region; TAS:Reactome.::GO:0000139; C:Golgi membrane; TAS:Reactome.::GO:0005887; C:integral to plasma membrane; TAS:UniProtKB.::GO:0005654; C:nucleoplasm; TAS:Reactome.
GO:0005509; F:calcium ion binding; TAS:UniProtKB.::GO:0046982; F:protein heterodimerization activity; TAS:UniProtKB.::GO:0004872; F:receptor activity; TAS:UniProtKB.
GO:0001709; P:cell fate determination; TAS:UniProtKB.::GO:0009790; P:embryo development; ISS:UniProtKB.::GO:0030097; P:hemopoiesis; TAS:UniProtKB.::GO:0030879; P:mammary gland development; IDA:UniProtKB.::GO:0045602; P:negative regulation of endothelial cell differentiation; ISS:UniProtKB.::GO:0007220; P:Notch receptor processing; TAS:Reactome.::GO:0007219; P:Notch signaling pathway; TAS:Reactome.::GO:0001569; P:patterning of blood vessels; ISS:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; TAS:UniProtKB.::GO:0006367; P:transcription initiation from RNA polymerase II promoter; TAS:Reactome.
109Q5GIG6    834   TNI3K_MOUSE Serine/threonine-protein kinase T...1730.0000004     53.5     29     45GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
110P0CS66    776   AKR1_CRYNJ Palmitoyltransferase AKR1 OS=ATCC ...2110.000000002     60.5     28     42GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0016746; F:transferase activity, transferring acyl groups; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
111P0CS67    776   AKR1_CRYNB Palmitoyltransferase AKR1 OS=(Filo...2110.000000002     60.5     28     42GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0016746; F:transferase activity, transferring acyl groups; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
112Q495B1    522   AKD1A_HUMAN Ankyrin repeat and death domain-c...1200.005     41.2     23     48
GO:0007165; P:signal transduction; IEA:InterPro.
113O35516    2470   NOTC2_MOUSE Neurogenic locus notch homolog pr...1430.003     42.4     25     45GO:0009986; C:cell surface; ISS:UniProtKB.::GO:0005887; C:integral to plasma membrane; IC:UniProtKB.::GO:0005634; C:nucleus; IDA:UniProtKB.
GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0019899; F:enzyme binding; IPI:UniProtKB.::GO:0051059; F:NF-kappaB binding; IPI:UniProtKB.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW.
GO:0007050; P:cell cycle arrest; ISS:UniProtKB.::GO:0001709; P:cell fate determination; TAS:UniProtKB.::GO:0016049; P:cell growth; ISS:UniProtKB.::GO:0007368; P:determination of left/right symmetry; IMP:MGI.::GO:0030326; P:embryonic limb morphogenesis; IGI:MGI.::GO:0072104; P:glomerular capillary formation; IEP:UniProtKB.::GO:0072015; P:glomerular visceral epithelial cell development; IEP:UniProtKB.::GO:0006959; P:humoral immune response; IGI:MGI.::GO:0002437; P:inflammatory response to antigenic stimulus; IGI:MGI.::GO:0072602; P:interleukin-4 secretion; IGI:MGI.::GO:0002011; P:morphogenesis of an epithelial sheet; IMP:MGI.::GO:0008285; P:negative regulation of cell proliferation; ISS:UniProtKB.::GO:0007219; P:Notch signaling pathway; TAS:UniProtKB.::GO:0009887; P:organ morphogenesis; TAS:UniProtKB.::GO:0043065; P:positive regulation of apoptotic process; IGI:MGI.::GO:0045672; P:positive regulation of osteoclast differentiation; IDA:UniProtKB.::GO:0046579; P:positive regulation of Ras protein signal transduction; ISS:UniProtKB.::GO:0072014; P:proximal tubule development; IEP:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0042060; P:wound healing; IDA:UniProtKB.
114A6QPE7    395   ANR65_BOVIN Ankyrin repeat domain-containing ...1060.29     35.4     29     42
115Q5RF15    618   TNI3K_PONAB Serine/threonine-protein kinase T...2130.000006     50.1     28     42GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
116Q59H18    835   TNI3K_HUMAN Serine/threonine-protein kinase T...1890.000007     50.1     26     44GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0008022; F:protein C-terminus binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0031013; F:troponin I binding; IPI:UniProtKB.
117Q96NW4    1050   ANR27_HUMAN Ankyrin repeat domain-containing ...1570.012     40     27     43GO:0005769; C:early endosome; IDA:MGI.::GO:0005764; C:lysosome; IDA:LIFEdb.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0005085; F:guanyl-nucleotide exchange factor activity; IDA:MGI.
GO:0045022; P:early endosome to late endosome transport; IDA:MGI.
118Q4ULZ2    305   Y580_RICFE Putative ankyrin repeat protein RF...1310.001     42.7     28     45
119O70445    765   BARD1_MOUSE BRCA1-associated RING domain prot...881.4     33.5     32     49GO:0031436; C:BRCA1-BARD1 complex; ISS:UniProtKB.::GO:0005737; C:cytoplasm; ISS:UniProtKB.
GO:0046982; F:protein heterodimerization activity; ISS:UniProtKB.::GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0043066; P:negative regulation of apoptotic process; ISS:UniProtKB.::GO:0046826; P:negative regulation of protein export from nucleus; ISS:UniProtKB.::GO:0043065; P:positive regulation of apoptotic process; ISS:UniProtKB.::GO:0085020; P:protein K6-linked ubiquitination; ISS:UniProtKB.::GO:0042325; P:regulation of phosphorylation; ISS:UniProtKB.
120P31695    1964   NOTC4_MOUSE Neurogenic locus notch homolog pr...1450.0002     45.4     30     47GO:0009986; C:cell surface; ISS:UniProtKB.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0009790; P:embryo development; IMP:UniProtKB.::GO:0045602; P:negative regulation of endothelial cell differentiation; IMP:UniProtKB.::GO:0007219; P:Notch signaling pathway; TAS:UniProtKB.::GO:0001569; P:patterning of blood vessels; IMP:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
121Q876A6    757   AKR1_NAUCC Palmitoyltransferase AKR1 OS=Y-126...1730.00001     49.3     28     39GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0016746; F:transferase activity, transferring acyl groups; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
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