Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YGR232W
Length:
228
Number of sequences:
5887
Description:
YGR232W NAS6 SGDID:S000003464, Chr VII from 953960-954646, Genome Release 64-1-1, Verified ORF, "Proteasome-interacting protein involved in the assembly of the base subcomplex of the 19S proteasomal regulatory particle (RP); ortholog of human oncoprotein gankyrin, which interacts with the Rb tumor suppressor and CDK4/6"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
481Q9J5I3    700   V018_FOWPN Putative ankyrin repeat protein FP...1341.8     33.1     22     46
482P62775    118   MTPN_RAT Myotrophin OS=Rattus norvegicus (Rat...870.25     34.3     33     45GO:0030424; C:axon; IDA:RGD.::GO:0005829; C:cytosol; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:UniProtKB.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.
GO:0005515; F:protein binding; IPI:IntAct.
GO:0006584; P:catecholamine metabolic process; IEP:RGD.::GO:0021707; P:cerebellar granule cell differentiation; IEP:RGD.::GO:0010613; P:positive regulation of cardiac muscle hypertrophy; IMP:UniProtKB.::GO:0030307; P:positive regulation of cell growth; IDA:UniProtKB.::GO:0010557; P:positive regulation of macromolecule biosynthetic process; IDA:UniProtKB.::GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; IDA:UniProtKB.::GO:0051247; P:positive regulation of protein metabolic process; IDA:UniProtKB.::GO:2000812; P:regulation of barbed-end actin filament capping; ISS:UniProtKB.::GO:0043403; P:skeletal muscle tissue regeneration; IEP:RGD.::GO:0051146; P:striated muscle cell differentiation; IEP:RGD.
483P62774    118   MTPN_MOUSE Myotrophin OS=Mus musculus (Mouse)...870.25     34.3     33     45GO:0005829; C:cytosol; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.
GO:0010613; P:positive regulation of cardiac muscle hypertrophy; ISS:UniProtKB.::GO:0030307; P:positive regulation of cell growth; ISS:UniProtKB.::GO:0010557; P:positive regulation of macromolecule biosynthetic process; ISS:UniProtKB.::GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; ISS:UniProtKB.::GO:0051247; P:positive regulation of protein metabolic process; ISS:UniProtKB.::GO:2000812; P:regulation of barbed-end actin filament capping; ISS:UniProtKB.
484Q2QL82    1647   CTTB2_MICMU Cortactin-binding protein 2 OS=Mi...1730.0005     44.3     26     46
485Q55A55    986   Y9848_DICDI Probable serine/threonine-protein...1310.17     36.6     26     44
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
486Q07DX4    1663   CTTB2_NOMLE Cortactin-binding protein 2 OS=le...1740.001     43.1     27     45
487Q1RI12    694   Y921_RICBR Putative ankyrin repeat protein RB...1480.0005     44.3     26     45
488P58546    118   MTPN_HUMAN Myotrophin OS=Homo sapiens (Human)...610.36     33.9     34     48GO:0005829; C:cytosol; ISS:UniProtKB.::GO:0008290; C:F-actin capping protein complex; IDA:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.
GO:0016049; P:cell growth; IDA:UniProtKB.::GO:0010613; P:positive regulation of cardiac muscle hypertrophy; IMP:UniProtKB.::GO:0030307; P:positive regulation of cell growth; ISS:UniProtKB.::GO:0010557; P:positive regulation of macromolecule biosynthetic process; ISS:UniProtKB.::GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; ISS:UniProtKB.::GO:0051247; P:positive regulation of protein metabolic process; ISS:UniProtKB.::GO:2000812; P:regulation of barbed-end actin filament capping; IDA:UniProtKB.::GO:0016202; P:regulation of striated muscle tissue development; NAS:UniProtKB.::GO:0006417; P:regulation of translation; NAS:UniProtKB.
489Q863Z4    118   MTPN_CANFA Myotrophin OS=Canis familiaris (Do...610.36     33.9     34     48GO:0030424; C:axon; ISS:AgBase.::GO:0005829; C:cytosol; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.
GO:0010613; P:positive regulation of cardiac muscle hypertrophy; ISS:UniProtKB.::GO:0030307; P:positive regulation of cell growth; ISS:UniProtKB.::GO:0010557; P:positive regulation of macromolecule biosynthetic process; ISS:UniProtKB.::GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; ISS:UniProtKB.::GO:0051247; P:positive regulation of protein metabolic process; ISS:UniProtKB.::GO:2000812; P:regulation of barbed-end actin filament capping; ISS:UniProtKB.
490Q3T0F7    118   MTPN_BOVIN Myotrophin OS=Bos taurus (Bovine)....610.36     33.9     34     48GO:0030424; C:axon; ISS:AgBase.::GO:0005829; C:cytosol; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.
GO:0005515; F:protein binding; IPI:IntAct.
GO:0010613; P:positive regulation of cardiac muscle hypertrophy; ISS:UniProtKB.::GO:0030307; P:positive regulation of cell growth; ISS:UniProtKB.::GO:0010557; P:positive regulation of macromolecule biosynthetic process; ISS:UniProtKB.::GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; ISS:UniProtKB.::GO:0051247; P:positive regulation of protein metabolic process; ISS:UniProtKB.::GO:2000812; P:regulation of barbed-end actin filament capping; ISS:UniProtKB.
491P77736    201   YAHD_ECOLI Putative ankyrin repeat protein Ya...1870.0005     43.1     22     39
492P17442    1178   PHO81_YEAST Phosphate system positive regulat...1869     31.2     25     39GO:0005737; C:cytoplasm; IDA:SGD.::GO:0005634; C:nucleus; IDA:SGD.
GO:0004861; F:cyclin-dependent protein kinase inhibitor activity; TAS:SGD.::GO:0008081; F:phosphoric diester hydrolase activity; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0006629; P:lipid metabolic process; IEA:InterPro.::GO:0006796; P:phosphate-containing compound metabolic process; IMP:SGD.
493Q00653    900   NFKB2_HUMAN Nuclear factor NF-kappa-B p100 su...814.3     32.3     27     47GO:0033257; C:Bcl3/NF-kappaB2 complex; IDA:UniProtKB.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0005654; C:nucleoplasm; TAS:Reactome.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.::GO:0003713; F:transcription coactivator activity; TAS:ProtInc.
GO:0045087; P:innate immune response; TAS:Reactome.::GO:0002755; P:MyD88-dependent toll-like receptor signaling pathway; TAS:Reactome.::GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; TAS:Reactome.::GO:0032481; P:positive regulation of type I interferon production; TAS:Reactome.::GO:0008063; P:Toll signaling pathway; TAS:Reactome.::GO:0034130; P:toll-like receptor 1 signaling pathway; TAS:Reactome.::GO:0034134; P:toll-like receptor 2 signaling pathway; TAS:Reactome.::GO:0034138; P:toll-like receptor 3 signaling pathway; TAS:Reactome.::GO:0034142; P:toll-like receptor 4 signaling pathway; TAS:Reactome.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0035666; P:TRIF-dependent toll-like receptor signaling pathway; TAS:Reactome.
494Q8CG79    1128   ASPP2_MOUSE Apoptosis-stimulating of p53 prot...705.7     32     30     44GO:0005634; C:nucleus; ISS:UniProtKB.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.
GO:0017124; F:SH3 domain binding; IEA:UniProtKB-KW.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0007417; P:central nervous system development; IMP:MGI.::GO:0009792; P:embryo development ending in birth or egg hatching; IGI:MGI.::GO:0007507; P:heart development; IMP:MGI.::GO:0006917; P:induction of apoptosis; ISS:UniProtKB.::GO:0010212; P:response to ionizing radiation; IMP:MGI.
495Q2QLF8    1662   CTTB2_CALJA Cortactin-binding protein 2 OS=Ca...1740.001     43.1     27     44
496Q2IBF7    1663   CTTB2_GORGO Cortactin-binding protein 2 OS=Go...1740.001     43.5     27     45
497Q09YJ3    1642   CTTB2_MUNMU Cortactin-binding protein 2 OS=Mu...1730.002     42.7     25     46
498Q2QLG9    1655   CTTB2_OTOGA Cortactin-binding protein 2 OS=Ot...1338.1     31.2     23     41
499Q55FM5    120   MTPN_DICDI Myotrophin homolog OS=Dictyosteliu...860.007     38.9     28     44GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
500O00522    736   KRIT1_HUMAN Krev interaction trapped protein ...1650.01     40.4     27     47GO:0005911; C:cell-cell junction; IDA:UniProtKB.::GO:0005856; C:cytoskeleton; IEA:InterPro.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
GO:0005488; F:binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0005083; F:small GTPase regulator activity; TAS:ProtInc.
GO:0001525; P:angiogenesis; IEA:UniProtKB-KW.::GO:0045454; P:cell redox homeostasis; IMP:UniProtKB.::GO:0016525; P:negative regulation of angiogenesis; IMP:UniProtKB.::GO:2000352; P:negative regulation of endothelial cell apoptotic process; IMP:UniProtKB.::GO:0010596; P:negative regulation of endothelial cell migration; IMP:UniProtKB.::GO:0001937; P:negative regulation of endothelial cell proliferation; IMP:UniProtKB.::GO:2000114; P:regulation of establishment of cell polarity; IMP:UniProtKB.::GO:0007264; P:small GTPase mediated signal transduction; TAS:ProtInc.
501Q1RHT6    614   Y997_RICBR Putative ankyrin repeat protein RB...1650.32     35.4     24     45
GO:0016787; F:hydrolase activity; IEA:InterPro.
GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-KW.
502Q2T9W8    424   ANR61_BOVIN Ankyrin repeat domain-containing ...2210.13     36.6     23     39
503Q9D738    308   ASB12_MOUSE Ankyrin repeat and SOCS box prote...1672.3     32.7     27     37
GO:0035556; P:intracellular signal transduction; IEA:InterPro.
504Q1RIZ4    350   Y589_RICBR Putative ankyrin repeat protein RB...1480.0008     43.1     26     46
505Q6P686    214   OSTF1_RAT Osteoclast-stimulating factor 1 OS=...890.0008     42.7     27     52GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
506Q80UP3    929   DGKZ_MOUSE Diacylglycerol kinase zeta OS=Mus ...910.0009     43.5     31     42GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004143; F:diacylglycerol kinase activity; IEA:EC.::GO:0004857; F:enzyme inhibitor activity; IDA:MGI.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0007205; P:activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway; IEA:InterPro.::GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0046580; P:negative regulation of Ras protein signal transduction; IMP:MGI.
507Q8N6D5    301   ANR29_HUMAN Ankyrin repeat domain-containing ...1760.085     37     26     44
508Q62422    215   OSTF1_MOUSE Osteoclast-stimulating factor 1 O...890.0009     42.7     27     52GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0017124; F:SH3 domain binding; IDA:MGI.
509Q4UKY3    226   Y939_RICFE Putative ankyrin repeat protein RF...1260.0009     42.7     32     49
510Q07DZ5    1635   CTTB2_ORNAN Cortactin-binding protein 2 OS=Or...1270.17     36.6     31     47
511Q09YM8    1664   CTTB2_RABIT Cortactin-binding protein 2 OS=Or...2210.006     41.2     22     38
records
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