Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YGR217W
Length:
2039
Number of sequences:
5887
Description:
YGR217W CCH1 SGDID:S000003449, Chr VII from 924696-930815, Genome Release 64-1-1, Verified ORF, "Voltage-gated high-affinity calcium channel involved in calcium influx in response to some environmental stresses as well as exposure to mating pheromones; interacts and co-localizes with Mid1p, suggesting Cch1p and Mid1p function together"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
1P50077    2039   CCH1_YEAST Calcium-channel protein CCH1 OS=Sa...20390     4210     100     100GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IDA:SGD.
GO:0005245; F:voltage-gated calcium channel activity; ISS:SGD.
GO:0006950; P:response to stress; IEA:UniProtKB-KW.
2O14234    1854   CCH1_SCHPO Calcium-channel protein cch1 OS=Sc...1060.58     38.9     28     46GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005887; C:integral to plasma membrane; NAS:PomBase.::GO:0005891; C:voltage-gated calcium channel complex; IEA:InterPro.
GO:0005245; F:voltage-gated calcium channel activity; IEA:InterPro.
GO:0050850; P:positive regulation of calcium-mediated signaling; IMP:PomBase.::GO:0032516; P:positive regulation of phosphoprotein phosphatase activity; IMP:PomBase.
3Q8IZF0    1738   NALCN_HUMAN Sodium leak channel non-selective...5420.002     47     20     37GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0005272; F:sodium channel activity; IEA:UniProtKB-KW.::GO:0005244; F:voltage-gated ion channel activity; IEA:UniProtKB-KW.
4Q8BXR5    1738   NALCN_MOUSE Sodium leak channel non-selective...5420.002     47.4     20     37GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0005272; F:sodium channel activity; IEA:UniProtKB-KW.::GO:0005244; F:voltage-gated ion channel activity; IEA:UniProtKB-KW.
5Q6Q760    1738   NALCN_RAT Sodium leak channel non-selective p...5420.001     47.8     20     37GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0005272; F:sodium channel activity; IEA:UniProtKB-KW.::GO:0005244; F:voltage-gated ion channel activity; IEA:UniProtKB-KW.
6Q01815    2139   CAC1C_MOUSE Voltage-dependent L-type calcium ...2760.0000000003     69.7     25     42GO:0002095; C:caveolar macromolecular signaling complex; IDA:MGI.::GO:0043198; C:dendritic shaft; IDA:MGI.::GO:0005624; C:membrane fraction; IDA:MGI.::GO:0043025; C:neuronal cell body; IDA:MGI.::GO:0030315; C:T-tubule; TAS:MGI.::GO:0005891; C:voltage-gated calcium channel complex; TAS:MGI.
GO:0005515; F:protein binding; IPI:MGI.::GO:0005245; F:voltage-gated calcium channel activity; IDA:MGI.
GO:0007628; P:adult walking behavior; IGI:MGI.::GO:0017156; P:calcium ion-dependent exocytosis; IMP:MGI.::GO:0006874; P:cellular calcium ion homeostasis; IMP:MGI.::GO:0042593; P:glucose homeostasis; IMP:MGI.::GO:0030252; P:growth hormone secretion; IDA:MGI.::GO:0030073; P:insulin secretion; IMP:MGI.::GO:0008217; P:regulation of blood pressure; IMP:MGI.::GO:0046620; P:regulation of organ growth; IMP:MGI.::GO:0019229; P:regulation of vasoconstriction; IMP:MGI.::GO:0060083; P:smooth muscle contraction involved in micturition; IMP:MGI.::GO:0007268; P:synaptic transmission; IMP:MGI.::GO:0008542; P:visual learning; IMP:MGI.
7C9D7C2    1904   CAC1A_APIME Voltage-dependent calcium channel...750.5     39.3     24     52GO:0005891; C:voltage-gated calcium channel complex; IEA:InterPro.
GO:0005245; F:voltage-gated calcium channel activity; IEA:InterPro.
8P15381    2171   CAC1C_RABIT Voltage-dependent L-type calcium ...2760.00000000007     72     25     42GO:0014069; C:postsynaptic density; ISS:UniProtKB.::GO:0005891; C:voltage-gated calcium channel complex; ISS:UniProtKB.
GO:0005516; F:calmodulin binding; ISS:UniProtKB.::GO:0005245; F:voltage-gated calcium channel activity; ISS:UniProtKB.
GO:0007204; P:elevation of cytosolic calcium ion concentration; ISS:UniProtKB.
9O57483    1688   CAC1S_LITCT Voltage-dependent L-type calcium ...2770.32     40     20     41GO:0005891; C:voltage-gated calcium channel complex; IEA:InterPro.
GO:0005245; F:voltage-gated calcium channel activity; IEA:InterPro.
10P22002    2169   CAC1C_RAT Voltage-dependent L-type calcium ch...5720.000002     57     20     40GO:0005624; C:membrane fraction; IDA:RGD.::GO:0043025; C:neuronal cell body; IDA:UniProtKB.::GO:0014069; C:postsynaptic density; IDA:UniProtKB.::GO:0030315; C:T-tubule; IDA:RGD.::GO:0005891; C:voltage-gated calcium channel complex; IDA:RGD.
GO:0019904; F:protein domain specific binding; IPI:RGD.::GO:0051721; F:protein phosphatase 2A binding; IPI:RGD.::GO:0005245; F:voltage-gated calcium channel activity; IDA:RGD.
11Q25452    1687   CAC1M_MUSDO Muscle calcium channel subunit al...1115.4     35.8     23     45GO:0005891; C:voltage-gated calcium channel complex; IEA:InterPro.
GO:0005245; F:voltage-gated calcium channel activity; IEA:InterPro.
12P91645    1851   CAC1A_DROME Voltage-dependent calcium channel...2578.2     35.4     22     46GO:0016324; C:apical plasma membrane; IDA:FlyBase.::GO:0016323; C:basolateral plasma membrane; IDA:FlyBase.::GO:0048786; C:presynaptic active zone; IDA:FlyBase.::GO:0005891; C:voltage-gated calcium channel complex; NAS:FlyBase.
GO:0005245; F:voltage-gated calcium channel activity; IDA:FlyBase.
GO:0008344; P:adult locomotory behavior; IMP:FlyBase.::GO:0050908; P:detection of light stimulus involved in visual perception; IMP:FlyBase.::GO:0042045; P:epithelial fluid transport; IDA:FlyBase.::GO:0006887; P:exocytosis; IMP:FlyBase.::GO:0045433; P:male courtship behavior, veined wing generated song production; IMP:FlyBase.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0007269; P:neurotransmitter secretion; IMP:FlyBase.::GO:0007602; P:phototransduction; NAS:FlyBase.::GO:0045887; P:positive regulation of synaptic growth at neuromuscular junction; IMP:FlyBase.::GO:0002027; P:regulation of heart rate; IMP:FlyBase.::GO:0046928; P:regulation of neurotransmitter secretion; IGI:FlyBase.::GO:0007632; P:visual behavior; NAS:FlyBase.
13Q13936    2221   CAC1C_HUMAN Voltage-dependent L-type calcium ...5950.00000001     64.3     21     41GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0014069; C:postsynaptic density; IDA:UniProtKB.::GO:0005891; C:voltage-gated calcium channel complex; IDA:UniProtKB.
GO:0005516; F:calmodulin binding; IPI:UniProtKB.::GO:0005245; F:voltage-gated calcium channel activity; IDA:UniProtKB.
GO:0007411; P:axon guidance; TAS:Reactome.::GO:0060402; P:calcium ion transport into cytosol; TAS:BHF-UCL.::GO:0006112; P:energy reserve metabolic process; TAS:Reactome.::GO:0050796; P:regulation of insulin secretion; TAS:Reactome.::GO:0044281; P:small molecule metabolic process; TAS:Reactome.
14P22316    1852   CAC1S_CYPCA Dihydropyridine-sensitive L-type ...2934.8     36.2     22     40GO:0005891; C:voltage-gated calcium channel complex; IEA:InterPro.
GO:0005245; F:voltage-gated calcium channel activity; IEA:InterPro.
15Q9W0Y8    2821   SCN60_DROME Sodium channel protein 60E OS=Dro...890.12     41.2     27     48GO:0001518; C:voltage-gated sodium channel complex; IEA:InterPro.
GO:0005248; F:voltage-gated sodium channel activity; NAS:FlyBase.
GO:0042048; P:olfactory behavior; IMP:FlyBase.::GO:0007608; P:sensory perception of smell; IEA:UniProtKB-KW.
16Q02789    1880   CAC1S_MOUSE Voltage-dependent L-type calcium ...2780.0000001     61.6     22     42GO:0005891; C:voltage-gated calcium channel complex; IEA:InterPro.
GO:0005245; F:voltage-gated calcium channel activity; IEA:InterPro.
17P07293    1873   CAC1S_RABIT Voltage-dependent L-type calcium ...2780.00000006     62     22     42GO:0005891; C:voltage-gated calcium channel complex; IEA:InterPro.
GO:0005245; F:voltage-gated calcium channel activity; IEA:InterPro.
18Q00975    2339   CAC1B_HUMAN Voltage-dependent N-type calcium ...1908.8     35     25     44GO:0005891; C:voltage-gated calcium channel complex; TAS:ProtInc.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008022; F:protein C-terminus binding; IPI:UniProtKB.::GO:0005245; F:voltage-gated calcium channel activity; TAS:ProtInc.
GO:0051899; P:membrane depolarization; TAS:Reactome.::GO:0007268; P:synaptic transmission; TAS:Reactome.
19Q13698    1873   CAC1S_HUMAN Voltage-dependent L-type calcium ...973.5     36.6     26     48GO:0031674; C:I band; IDA:UniProtKB.::GO:0030315; C:T-tubule; IDA:UniProtKB.::GO:0005891; C:voltage-gated calcium channel complex; IDA:UniProtKB.
GO:0008331; F:high voltage-gated calcium channel activity; IDA:UniProtKB.
GO:0007411; P:axon guidance; TAS:Reactome.
20P35500    2131   SCNA_DROME Sodium channel protein para OS=Dro...1199.7     35     26     41GO:0001518; C:voltage-gated sodium channel complex; IEA:InterPro.
GO:0005248; F:voltage-gated sodium channel activity; IDA:FlyBase.
GO:0045433; P:male courtship behavior, veined wing generated song production; IMP:FlyBase.::GO:0007638; P:mechanosensory behavior; IMP:FlyBase.::GO:0046680; P:response to DDT; IDA:FlyBase.::GO:0001666; P:response to hypoxia; IDA:FlyBase.::GO:0046684; P:response to pyrethroid; IMP:FlyBase.::GO:0007268; P:synaptic transmission; TAS:FlyBase.
21Q14524    2016   SCN5A_HUMAN Sodium channel protein type 5 sub...866.9     35.4     29     49GO:0009986; C:cell surface; IDA:BHF-UCL.::GO:0042383; C:sarcolemma; IDA:BHF-UCL.::GO:0001518; C:voltage-gated sodium channel complex; IC:BHF-UCL.
GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0005248; F:voltage-gated sodium channel activity; IDA:UniProtKB.
GO:0008015; P:blood circulation; NAS:ProtInc.::GO:0061337; P:cardiac conduction; IMP:BHF-UCL.::GO:0071277; P:cellular response to calcium ion; IDA:UniProtKB.::GO:0045760; P:positive regulation of action potential; IDA:BHF-UCL.::GO:0060452; P:positive regulation of cardiac muscle contraction; IMP:BHF-UCL.::GO:0060371; P:regulation of atrial cardiomyocyte membrane depolarization; TAS:BHF-UCL.::GO:0060372; P:regulation of atrial cardiomyocyte membrane repolarization; TAS:BHF-UCL.::GO:0002027; P:regulation of heart rate; IMP:BHF-UCL.::GO:0060373; P:regulation of ventricular cardiomyocyte membrane depolarization; TAS:BHF-UCL.::GO:0060307; P:regulation of ventricular cardiomyocyte membrane repolarization; TAS:BHF-UCL.
22Q9R053    1765   SCNBA_MOUSE Sodium channel protein type 11 su...2433.7     36.6     18     42GO:0044299; C:C-fiber; IDA:MGI.::GO:0001518; C:voltage-gated sodium channel complex; IEA:InterPro.
GO:0005248; F:voltage-gated sodium channel activity; IDA:MGI.
23Q6QIY3    1958   SCNAA_MOUSE Sodium channel protein type 10 su...2126.3     35.8     20     42GO:0044299; C:C-fiber; IDA:MGI.::GO:0001518; C:voltage-gated sodium channel complex; IEA:InterPro.
GO:0005248; F:voltage-gated sodium channel activity; IDA:MGI.
24Q02294    2336   CAC1B_RAT Voltage-dependent N-type calcium ch...1874.6     36.2     25     42GO:0043679; C:axon terminus; IDA:RGD.::GO:0043198; C:dendritic shaft; IDA:RGD.::GO:0043025; C:neuronal cell body; IDA:RGD.::GO:0019717; C:synaptosome; IDA:RGD.::GO:0005891; C:voltage-gated calcium channel complex; IEA:InterPro.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0005245; F:voltage-gated calcium channel activity; IMP:RGD.
GO:0001956; P:positive regulation of neurotransmitter secretion; IMP:RGD.::GO:0045471; P:response to ethanol; IEP:RGD.::GO:0014070; P:response to organic cyclic compound; IDA:RGD.::GO:0033574; P:response to testosterone stimulus; IMP:RGD.
25P15389    2019   SCN5A_RAT Sodium channel protein type 5 subun...863.3     36.6     30     49GO:0001518; C:voltage-gated sodium channel complex; TAS:RGD.
GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0005248; F:voltage-gated sodium channel activity; ISS:UniProtKB.
GO:0071277; P:cellular response to calcium ion; ISS:UniProtKB.
26Q9JJV9    2019   SCN5A_MOUSE Sodium channel protein type 5 sub...863.6     36.6     30     49GO:0014704; C:intercalated disc; IDA:MGI.::GO:0030315; C:T-tubule; IDA:MGI.::GO:0001518; C:voltage-gated sodium channel complex; IC:MGI.
GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0005248; F:voltage-gated sodium channel activity; IDA:MGI.
GO:0071277; P:cellular response to calcium ion; ISS:UniProtKB.
27O55017    2327   CAC1B_MOUSE Voltage-dependent N-type calcium ...1875.3     35.8     25     42GO:0030425; C:dendrite; IDA:MGI.::GO:0043025; C:neuronal cell body; IDA:MGI.::GO:0005891; C:voltage-gated calcium channel complex; IDA:MGI.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:MGI.::GO:0005245; F:voltage-gated calcium channel activity; IMP:MGI.
GO:0007626; P:locomotory behavior; IMP:MGI.::GO:0007269; P:neurotransmitter secretion; IMP:MGI.::GO:0008217; P:regulation of blood pressure; IMP:MGI.::GO:0008016; P:regulation of heart contraction; IMP:MGI.::GO:0048265; P:response to pain; IMP:MGI.
28P27732    2203   CAC1D_RAT Voltage-dependent L-type calcium ch...700.44     39.7     26     56GO:0005891; C:voltage-gated calcium channel complex; IEA:InterPro.
GO:0005245; F:voltage-gated calcium channel activity; IEA:InterPro.
29Q24270    2516   CAC1D_DROME Voltage-dependent calcium channel...780.44     39.7     27     54GO:0016324; C:apical plasma membrane; IDA:FlyBase.::GO:0016323; C:basolateral plasma membrane; IDA:FlyBase.::GO:0005891; C:voltage-gated calcium channel complex; NAS:FlyBase.
GO:0005245; F:voltage-gated calcium channel activity; NAS:FlyBase.
GO:0042045; P:epithelial fluid transport; IDA:FlyBase.::GO:0006936; P:muscle contraction; TAS:FlyBase.
30Q02485    1146   CAC1S_RAT Voltage-dependent L-type calcium ch...2970.11     41.2     20     37GO:0005891; C:voltage-gated calcium channel complex; IDA:RGD.
GO:0005245; F:voltage-gated calcium channel activity; IDA:RGD.
GO:0001503; P:ossification; NAS:RGD.
31Q99250    2005   SCN2A_HUMAN Sodium channel protein type 2 sub...900.095     41.6     30     48GO:0033268; C:node of Ranvier; ISS:BHF-UCL.::GO:0001518; C:voltage-gated sodium channel complex; IEA:InterPro.
GO:0005248; F:voltage-gated sodium channel activity; TAS:ProtInc.
GO:0042552; P:myelination; ISS:BHF-UCL.
records
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