rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
1 | P50077 | 2039 | CCH1_YEAST Calcium-channel protein CCH1 OS=Sa... | 2039 | 0 | 4210 | 100 | 100 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IDA:SGD. | | | | | | | | | | GO:0005245; F:voltage-gated calcium channel activity; ISS:SGD. | | | | | | | | | | GO:0006950; P:response to stress; IEA:UniProtKB-KW. | 2 | O14234 | 1854 | CCH1_SCHPO Calcium-channel protein cch1 OS=Sc... | 106 | 0.58 | 38.9 | 28 | 46 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005887; C:integral to plasma membrane; NAS:PomBase.::GO:0005891; C:voltage-gated calcium channel complex; IEA:InterPro. | | | | | | | | | | GO:0005245; F:voltage-gated calcium channel activity; IEA:InterPro. | | | | | | | | | | GO:0050850; P:positive regulation of calcium-mediated signaling; IMP:PomBase.::GO:0032516; P:positive regulation of phosphoprotein phosphatase activity; IMP:PomBase. | 3 | Q8IZF0 | 1738 | NALCN_HUMAN Sodium leak channel non-selective... | 542 | 0.002 | 47 | 20 | 37 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005272; F:sodium channel activity; IEA:UniProtKB-KW.::GO:0005244; F:voltage-gated ion channel activity; IEA:UniProtKB-KW. | | | | | | | | | | | 4 | Q8BXR5 | 1738 | NALCN_MOUSE Sodium leak channel non-selective... | 542 | 0.002 | 47.4 | 20 | 37 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005272; F:sodium channel activity; IEA:UniProtKB-KW.::GO:0005244; F:voltage-gated ion channel activity; IEA:UniProtKB-KW. | | | | | | | | | | | 5 | Q6Q760 | 1738 | NALCN_RAT Sodium leak channel non-selective p... | 542 | 0.001 | 47.8 | 20 | 37 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005272; F:sodium channel activity; IEA:UniProtKB-KW.::GO:0005244; F:voltage-gated ion channel activity; IEA:UniProtKB-KW. | | | | | | | | | | | 6 | Q01815 | 2139 | CAC1C_MOUSE Voltage-dependent L-type calcium ... | 276 | 0.0000000003 | 69.7 | 25 | 42 | GO:0002095; C:caveolar macromolecular signaling complex; IDA:MGI.::GO:0043198; C:dendritic shaft; IDA:MGI.::GO:0005624; C:membrane fraction; IDA:MGI.::GO:0043025; C:neuronal cell body; IDA:MGI.::GO:0030315; C:T-tubule; TAS:MGI.::GO:0005891; C:voltage-gated calcium channel complex; TAS:MGI. | | | | | | | | | | GO:0005515; F:protein binding; IPI:MGI.::GO:0005245; F:voltage-gated calcium channel activity; IDA:MGI. | | | | | | | | | | GO:0007628; P:adult walking behavior; IGI:MGI.::GO:0017156; P:calcium ion-dependent exocytosis; IMP:MGI.::GO:0006874; P:cellular calcium ion homeostasis; IMP:MGI.::GO:0042593; P:glucose homeostasis; IMP:MGI.::GO:0030252; P:growth hormone secretion; IDA:MGI.::GO:0030073; P:insulin secretion; IMP:MGI.::GO:0008217; P:regulation of blood pressure; IMP:MGI.::GO:0046620; P:regulation of organ growth; IMP:MGI.::GO:0019229; P:regulation of vasoconstriction; IMP:MGI.::GO:0060083; P:smooth muscle contraction involved in micturition; IMP:MGI.::GO:0007268; P:synaptic transmission; IMP:MGI.::GO:0008542; P:visual learning; IMP:MGI. | 7 | C9D7C2 | 1904 | CAC1A_APIME Voltage-dependent calcium channel... | 75 | 0.5 | 39.3 | 24 | 52 | GO:0005891; C:voltage-gated calcium channel complex; IEA:InterPro. | | | | | | | | | | GO:0005245; F:voltage-gated calcium channel activity; IEA:InterPro. | | | | | | | | | | | 8 | P15381 | 2171 | CAC1C_RABIT Voltage-dependent L-type calcium ... | 276 | 0.00000000007 | 72 | 25 | 42 | GO:0014069; C:postsynaptic density; ISS:UniProtKB.::GO:0005891; C:voltage-gated calcium channel complex; ISS:UniProtKB. | | | | | | | | | | GO:0005516; F:calmodulin binding; ISS:UniProtKB.::GO:0005245; F:voltage-gated calcium channel activity; ISS:UniProtKB. | | | | | | | | | | GO:0007204; P:elevation of cytosolic calcium ion concentration; ISS:UniProtKB. | 9 | O57483 | 1688 | CAC1S_LITCT Voltage-dependent L-type calcium ... | 277 | 0.32 | 40 | 20 | 41 | GO:0005891; C:voltage-gated calcium channel complex; IEA:InterPro. | | | | | | | | | | GO:0005245; F:voltage-gated calcium channel activity; IEA:InterPro. | | | | | | | | | | | 10 | P22002 | 2169 | CAC1C_RAT Voltage-dependent L-type calcium ch... | 572 | 0.000002 | 57 | 20 | 40 | GO:0005624; C:membrane fraction; IDA:RGD.::GO:0043025; C:neuronal cell body; IDA:UniProtKB.::GO:0014069; C:postsynaptic density; IDA:UniProtKB.::GO:0030315; C:T-tubule; IDA:RGD.::GO:0005891; C:voltage-gated calcium channel complex; IDA:RGD. | | | | | | | | | | GO:0019904; F:protein domain specific binding; IPI:RGD.::GO:0051721; F:protein phosphatase 2A binding; IPI:RGD.::GO:0005245; F:voltage-gated calcium channel activity; IDA:RGD. | | | | | | | | | | | 11 | Q25452 | 1687 | CAC1M_MUSDO Muscle calcium channel subunit al... | 111 | 5.4 | 35.8 | 23 | 45 | GO:0005891; C:voltage-gated calcium channel complex; IEA:InterPro. | | | | | | | | | | GO:0005245; F:voltage-gated calcium channel activity; IEA:InterPro. | | | | | | | | | | | 12 | P91645 | 1851 | CAC1A_DROME Voltage-dependent calcium channel... | 257 | 8.2 | 35.4 | 22 | 46 | GO:0016324; C:apical plasma membrane; IDA:FlyBase.::GO:0016323; C:basolateral plasma membrane; IDA:FlyBase.::GO:0048786; C:presynaptic active zone; IDA:FlyBase.::GO:0005891; C:voltage-gated calcium channel complex; NAS:FlyBase. | | | | | | | | | | GO:0005245; F:voltage-gated calcium channel activity; IDA:FlyBase. | | | | | | | | | | GO:0008344; P:adult locomotory behavior; IMP:FlyBase.::GO:0050908; P:detection of light stimulus involved in visual perception; IMP:FlyBase.::GO:0042045; P:epithelial fluid transport; IDA:FlyBase.::GO:0006887; P:exocytosis; IMP:FlyBase.::GO:0045433; P:male courtship behavior, veined wing generated song production; IMP:FlyBase.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0007269; P:neurotransmitter secretion; IMP:FlyBase.::GO:0007602; P:phototransduction; NAS:FlyBase.::GO:0045887; P:positive regulation of synaptic growth at neuromuscular junction; IMP:FlyBase.::GO:0002027; P:regulation of heart rate; IMP:FlyBase.::GO:0046928; P:regulation of neurotransmitter secretion; IGI:FlyBase.::GO:0007632; P:visual behavior; NAS:FlyBase. | 13 | Q13936 | 2221 | CAC1C_HUMAN Voltage-dependent L-type calcium ... | 595 | 0.00000001 | 64.3 | 21 | 41 | GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0014069; C:postsynaptic density; IDA:UniProtKB.::GO:0005891; C:voltage-gated calcium channel complex; IDA:UniProtKB. | | | | | | | | | | GO:0005516; F:calmodulin binding; IPI:UniProtKB.::GO:0005245; F:voltage-gated calcium channel activity; IDA:UniProtKB. | | | | | | | | | | GO:0007411; P:axon guidance; TAS:Reactome.::GO:0060402; P:calcium ion transport into cytosol; TAS:BHF-UCL.::GO:0006112; P:energy reserve metabolic process; TAS:Reactome.::GO:0050796; P:regulation of insulin secretion; TAS:Reactome.::GO:0044281; P:small molecule metabolic process; TAS:Reactome. | 14 | P22316 | 1852 | CAC1S_CYPCA Dihydropyridine-sensitive L-type ... | 293 | 4.8 | 36.2 | 22 | 40 | GO:0005891; C:voltage-gated calcium channel complex; IEA:InterPro. | | | | | | | | | | GO:0005245; F:voltage-gated calcium channel activity; IEA:InterPro. | | | | | | | | | | | 15 | Q9W0Y8 | 2821 | SCN60_DROME Sodium channel protein 60E OS=Dro... | 89 | 0.12 | 41.2 | 27 | 48 | GO:0001518; C:voltage-gated sodium channel complex; IEA:InterPro. | | | | | | | | | | GO:0005248; F:voltage-gated sodium channel activity; NAS:FlyBase. | | | | | | | | | | GO:0042048; P:olfactory behavior; IMP:FlyBase.::GO:0007608; P:sensory perception of smell; IEA:UniProtKB-KW. | 16 | Q02789 | 1880 | CAC1S_MOUSE Voltage-dependent L-type calcium ... | 278 | 0.0000001 | 61.6 | 22 | 42 | GO:0005891; C:voltage-gated calcium channel complex; IEA:InterPro. | | | | | | | | | | GO:0005245; F:voltage-gated calcium channel activity; IEA:InterPro. | | | | | | | | | | | 17 | P07293 | 1873 | CAC1S_RABIT Voltage-dependent L-type calcium ... | 278 | 0.00000006 | 62 | 22 | 42 | GO:0005891; C:voltage-gated calcium channel complex; IEA:InterPro. | | | | | | | | | | GO:0005245; F:voltage-gated calcium channel activity; IEA:InterPro. | | | | | | | | | | | 18 | Q00975 | 2339 | CAC1B_HUMAN Voltage-dependent N-type calcium ... | 190 | 8.8 | 35 | 25 | 44 | GO:0005891; C:voltage-gated calcium channel complex; TAS:ProtInc. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008022; F:protein C-terminus binding; IPI:UniProtKB.::GO:0005245; F:voltage-gated calcium channel activity; TAS:ProtInc. | | | | | | | | | | GO:0051899; P:membrane depolarization; TAS:Reactome.::GO:0007268; P:synaptic transmission; TAS:Reactome. | 19 | Q13698 | 1873 | CAC1S_HUMAN Voltage-dependent L-type calcium ... | 97 | 3.5 | 36.6 | 26 | 48 | GO:0031674; C:I band; IDA:UniProtKB.::GO:0030315; C:T-tubule; IDA:UniProtKB.::GO:0005891; C:voltage-gated calcium channel complex; IDA:UniProtKB. | | | | | | | | | | GO:0008331; F:high voltage-gated calcium channel activity; IDA:UniProtKB. | | | | | | | | | | GO:0007411; P:axon guidance; TAS:Reactome. | 20 | P35500 | 2131 | SCNA_DROME Sodium channel protein para OS=Dro... | 119 | 9.7 | 35 | 26 | 41 | GO:0001518; C:voltage-gated sodium channel complex; IEA:InterPro. | | | | | | | | | | GO:0005248; F:voltage-gated sodium channel activity; IDA:FlyBase. | | | | | | | | | | GO:0045433; P:male courtship behavior, veined wing generated song production; IMP:FlyBase.::GO:0007638; P:mechanosensory behavior; IMP:FlyBase.::GO:0046680; P:response to DDT; IDA:FlyBase.::GO:0001666; P:response to hypoxia; IDA:FlyBase.::GO:0046684; P:response to pyrethroid; IMP:FlyBase.::GO:0007268; P:synaptic transmission; TAS:FlyBase. | 21 | Q14524 | 2016 | SCN5A_HUMAN Sodium channel protein type 5 sub... | 86 | 6.9 | 35.4 | 29 | 49 | GO:0009986; C:cell surface; IDA:BHF-UCL.::GO:0042383; C:sarcolemma; IDA:BHF-UCL.::GO:0001518; C:voltage-gated sodium channel complex; IC:BHF-UCL. | | | | | | | | | | GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0005248; F:voltage-gated sodium channel activity; IDA:UniProtKB. | | | | | | | | | | GO:0008015; P:blood circulation; NAS:ProtInc.::GO:0061337; P:cardiac conduction; IMP:BHF-UCL.::GO:0071277; P:cellular response to calcium ion; IDA:UniProtKB.::GO:0045760; P:positive regulation of action potential; IDA:BHF-UCL.::GO:0060452; P:positive regulation of cardiac muscle contraction; IMP:BHF-UCL.::GO:0060371; P:regulation of atrial cardiomyocyte membrane depolarization; TAS:BHF-UCL.::GO:0060372; P:regulation of atrial cardiomyocyte membrane repolarization; TAS:BHF-UCL.::GO:0002027; P:regulation of heart rate; IMP:BHF-UCL.::GO:0060373; P:regulation of ventricular cardiomyocyte membrane depolarization; TAS:BHF-UCL.::GO:0060307; P:regulation of ventricular cardiomyocyte membrane repolarization; TAS:BHF-UCL. | 22 | Q9R053 | 1765 | SCNBA_MOUSE Sodium channel protein type 11 su... | 243 | 3.7 | 36.6 | 18 | 42 | GO:0044299; C:C-fiber; IDA:MGI.::GO:0001518; C:voltage-gated sodium channel complex; IEA:InterPro. | | | | | | | | | | GO:0005248; F:voltage-gated sodium channel activity; IDA:MGI. | | | | | | | | | | | 23 | Q6QIY3 | 1958 | SCNAA_MOUSE Sodium channel protein type 10 su... | 212 | 6.3 | 35.8 | 20 | 42 | GO:0044299; C:C-fiber; IDA:MGI.::GO:0001518; C:voltage-gated sodium channel complex; IEA:InterPro. | | | | | | | | | | GO:0005248; F:voltage-gated sodium channel activity; IDA:MGI. | | | | | | | | | | | 24 | Q02294 | 2336 | CAC1B_RAT Voltage-dependent N-type calcium ch... | 187 | 4.6 | 36.2 | 25 | 42 | GO:0043679; C:axon terminus; IDA:RGD.::GO:0043198; C:dendritic shaft; IDA:RGD.::GO:0043025; C:neuronal cell body; IDA:RGD.::GO:0019717; C:synaptosome; IDA:RGD.::GO:0005891; C:voltage-gated calcium channel complex; IEA:InterPro. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0005245; F:voltage-gated calcium channel activity; IMP:RGD. | | | | | | | | | | GO:0001956; P:positive regulation of neurotransmitter secretion; IMP:RGD.::GO:0045471; P:response to ethanol; IEP:RGD.::GO:0014070; P:response to organic cyclic compound; IDA:RGD.::GO:0033574; P:response to testosterone stimulus; IMP:RGD. | 25 | P15389 | 2019 | SCN5A_RAT Sodium channel protein type 5 subun... | 86 | 3.3 | 36.6 | 30 | 49 | GO:0001518; C:voltage-gated sodium channel complex; TAS:RGD. | | | | | | | | | | GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0005248; F:voltage-gated sodium channel activity; ISS:UniProtKB. | | | | | | | | | | GO:0071277; P:cellular response to calcium ion; ISS:UniProtKB. | 26 | Q9JJV9 | 2019 | SCN5A_MOUSE Sodium channel protein type 5 sub... | 86 | 3.6 | 36.6 | 30 | 49 | GO:0014704; C:intercalated disc; IDA:MGI.::GO:0030315; C:T-tubule; IDA:MGI.::GO:0001518; C:voltage-gated sodium channel complex; IC:MGI. | | | | | | | | | | GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0005248; F:voltage-gated sodium channel activity; IDA:MGI. | | | | | | | | | | GO:0071277; P:cellular response to calcium ion; ISS:UniProtKB. | 27 | O55017 | 2327 | CAC1B_MOUSE Voltage-dependent N-type calcium ... | 187 | 5.3 | 35.8 | 25 | 42 | GO:0030425; C:dendrite; IDA:MGI.::GO:0043025; C:neuronal cell body; IDA:MGI.::GO:0005891; C:voltage-gated calcium channel complex; IDA:MGI. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:MGI.::GO:0005245; F:voltage-gated calcium channel activity; IMP:MGI. | | | | | | | | | | GO:0007626; P:locomotory behavior; IMP:MGI.::GO:0007269; P:neurotransmitter secretion; IMP:MGI.::GO:0008217; P:regulation of blood pressure; IMP:MGI.::GO:0008016; P:regulation of heart contraction; IMP:MGI.::GO:0048265; P:response to pain; IMP:MGI. | 28 | P27732 | 2203 | CAC1D_RAT Voltage-dependent L-type calcium ch... | 70 | 0.44 | 39.7 | 26 | 56 | GO:0005891; C:voltage-gated calcium channel complex; IEA:InterPro. | | | | | | | | | | GO:0005245; F:voltage-gated calcium channel activity; IEA:InterPro. | | | | | | | | | | | 29 | Q24270 | 2516 | CAC1D_DROME Voltage-dependent calcium channel... | 78 | 0.44 | 39.7 | 27 | 54 | GO:0016324; C:apical plasma membrane; IDA:FlyBase.::GO:0016323; C:basolateral plasma membrane; IDA:FlyBase.::GO:0005891; C:voltage-gated calcium channel complex; NAS:FlyBase. | | | | | | | | | | GO:0005245; F:voltage-gated calcium channel activity; NAS:FlyBase. | | | | | | | | | | GO:0042045; P:epithelial fluid transport; IDA:FlyBase.::GO:0006936; P:muscle contraction; TAS:FlyBase. | 30 | Q02485 | 1146 | CAC1S_RAT Voltage-dependent L-type calcium ch... | 297 | 0.11 | 41.2 | 20 | 37 | GO:0005891; C:voltage-gated calcium channel complex; IDA:RGD. | | | | | | | | | | GO:0005245; F:voltage-gated calcium channel activity; IDA:RGD. | | | | | | | | | | GO:0001503; P:ossification; NAS:RGD. | 31 | Q99250 | 2005 | SCN2A_HUMAN Sodium channel protein type 2 sub... | 90 | 0.095 | 41.6 | 30 | 48 | GO:0033268; C:node of Ranvier; ISS:BHF-UCL.::GO:0001518; C:voltage-gated sodium channel complex; IEA:InterPro. | | | | | | | | | | GO:0005248; F:voltage-gated sodium channel activity; TAS:ProtInc. | | | | | | | | | | GO:0042552; P:myelination; ISS:BHF-UCL. |