Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YGR209C
Length:
104
Number of sequences:
5887
Description:
YGR209C TRX2 SGDID:S000003441, Chr VII from 913227-912913, Genome Release 64-1-1, reverse complement, Verified ORF, "Cytoplasmic thioredoxin isoenzyme of the thioredoxin system which protects cells against oxidative and reductive stress, forms LMA1 complex with Pbi2p, acts as a cofactor for Tsa1p, required for ER-Golgi transport and vacuole inheritance"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
271P80284    513   PDI_HORVU Protein disulfide-isomerase OS=Hord...910.000001     49.7     33     53GO:0005788; C:endoplasmic reticulum lumen; IEA:UniProtKB-SubCell.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0003756; F:protein disulfide isomerase activity; IEA:EC.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.
272Q91W90    417   TXND5_MOUSE Thioredoxin domain-containing pro...920.000001     49.3     33     47GO:0005788; C:endoplasmic reticulum lumen; IDA:UniProtKB.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0016853; F:isomerase activity; IEA:InterPro.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.
273P21609    107   THIO_CLOLI Thioredoxin OS=Clostridium litoral...790.0000003     48.5     30     53
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0006810; P:transport; IEA:UniProtKB-KW.
274P27773    505   PDIA3_MOUSE Protein disulfide-isomerase A3 OS...650.000009     47     37     54GO:0005788; C:endoplasmic reticulum lumen; TAS:Reactome.::GO:0042470; C:melanosome; IEA:UniProtKB-SubCell.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0003756; F:protein disulfide isomerase activity; IEA:EC.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0043065; P:positive regulation of apoptotic process; IMP:MGI.
275Q92249    369   ERP38_NEUCR Protein disulfide-isomerase erp38...710.000003     48.1     39     52GO:0005788; C:endoplasmic reticulum lumen; IEA:UniProtKB-SubCell.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0003756; F:protein disulfide isomerase activity; IEA:EC.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0006950; P:response to stress; IEA:UniProtKB-KW.
276P17967    522   PDI_YEAST Protein disulfide-isomerase OS=Sacc...730.0002     42.4     32     51GO:0005788; C:endoplasmic reticulum lumen; IDA:SGD.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0003756; F:protein disulfide isomerase activity; IDA:SGD.::GO:0015035; F:protein disulfide oxidoreductase activity; IDA:SGD.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0006457; P:protein folding; IMP:SGD.
277Q8R4U2    509   PDIA1_CRIGR Protein disulfide-isomerase OS=Cr...610.000002     49.3     38     57GO:0005788; C:endoplasmic reticulum lumen; IEA:UniProtKB-SubCell.::GO:0042470; C:melanosome; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0003756; F:protein disulfide isomerase activity; IEA:EC.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.
278O32171    106   YUSE_BACSU Thioredoxin-like protein yusE OS=B...690.0000005     47.8     29     55
GO:0045454; P:cell redox homeostasis; IEA:InterPro.
279P04785    509   PDIA1_RAT Protein disulfide-isomerase OS=Ratt...610.000001     49.3     38     57GO:0005788; C:endoplasmic reticulum lumen; IEA:UniProtKB-SubCell.::GO:0042470; C:melanosome; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0003756; F:protein disulfide isomerase activity; IMP:RGD.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.::GO:0046982; F:protein heterodimerization activity; IPI:RGD.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.
280Q54EN4    513   PDI2_DICDI Protein disulfide-isomerase 2 OS=D...800.000001     49.3     35     53GO:0005788; C:endoplasmic reticulum lumen; IEA:UniProtKB-SubCell.::GO:0005615; C:extracellular space; IDA:dictyBase.::GO:0045335; C:phagocytic vesicle; IDA:dictyBase.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0003756; F:protein disulfide isomerase activity; ISS:dictyBase.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0006457; P:protein folding; ISS:dictyBase.::GO:0009617; P:response to bacterium; IEP:dictyBase.::GO:0019953; P:sexual reproduction; IEP:dictyBase.
281P34329    618   PDIA4_CAEEL Probable protein disulfide-isomer...810.036     35.8     25     44GO:0005788; C:endoplasmic reticulum lumen; IEA:UniProtKB-SubCell.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0003756; F:protein disulfide isomerase activity; IEA:EC.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0030968; P:endoplasmic reticulum unfolded protein response; IEP:WormBase.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0040010; P:positive regulation of growth rate; IMP:WormBase.::GO:0040018; P:positive regulation of multicellular organism growth; IMP:WormBase.::GO:0000003; P:reproduction; IMP:WormBase.
282Q53LQ0    512   PDI11_ORYSJ Protein disulfide isomerase-like ...910.00005     44.7     32     51GO:0005788; C:endoplasmic reticulum lumen; IDA:UniProtKB.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0003756; F:protein disulfide isomerase activity; IEA:EC.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0034975; P:protein folding in endoplasmic reticulum; IMP:UniProtKB.
283P29828    512   PDI_MEDSA Protein disulfide-isomerase OS=Medi...830.0001     43.5     30     49GO:0005788; C:endoplasmic reticulum lumen; IEA:UniProtKB-SubCell.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0003756; F:protein disulfide isomerase activity; IEA:EC.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.
284Q6DFS0    287   TMX2_XENTR Thioredoxin-related transmembrane ...730.000001     48.9     30     58GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.
285P11598    505   PDIA3_RAT Protein disulfide-isomerase A3 OS=R...650.00002     45.8     37     54GO:0005788; C:endoplasmic reticulum lumen; IEA:UniProtKB-SubCell.::GO:0042470; C:melanosome; IEA:UniProtKB-SubCell.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0003756; F:protein disulfide isomerase activity; IEA:EC.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.
286Q9XI01    501   PDI11_ARATH Protein disulfide isomerase-like ...700.001     40.4     34     51GO:0009507; C:chloroplast; IDA:TAIR.::GO:0005788; C:endoplasmic reticulum lumen; IEA:UniProtKB-SubCell.::GO:0000327; C:lytic vacuole within protein storage vacuole; IDA:TAIR.::GO:0016020; C:membrane; IDA:TAIR.::GO:0009505; C:plant-type cell wall; IDA:TAIR.::GO:0009579; C:thylakoid; IDA:TAIR.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0003756; F:protein disulfide isomerase activity; ISS:TAIR.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0009790; P:embryo development; IMP:TAIR.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0043067; P:regulation of programmed cell death; IMP:TAIR.::GO:0034976; P:response to endoplasmic reticulum stress; IEP:TAIR.::GO:0009651; P:response to salt stress; IEP:TAIR.::GO:0010043; P:response to zinc ion; IEP:TAIR.::GO:0048316; P:seed development; IMP:TAIR.
287O48773    440   PDI23_ARATH Protein disulfide-isomerase 2-3 O...740.00005     44.3     27     53GO:0005788; C:endoplasmic reticulum lumen; IEA:UniProtKB-SubCell.::GO:0005794; C:Golgi apparatus; IDA:TAIR.::GO:0005886; C:plasma membrane; IDA:TAIR.::GO:0005773; C:vacuole; IDA:TAIR.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0003756; F:protein disulfide isomerase activity; ISS:TAIR.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0034976; P:response to endoplasmic reticulum stress; IEP:TAIR.
288Q58E26    287   TMX2_XENLA Thioredoxin-related transmembrane ...730.000001     48.9     33     58GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.
289Q39591    129   DYL4_CHLRE Dynein 14 kDa light chain, flagell...1040.000001     46.6     23     49GO:0005929; C:cilium; IEA:UniProtKB-KW.::GO:0030286; C:dynein complex; IEA:UniProtKB-KW.::GO:0035086; C:flagellar axoneme; IEA:UniProtKB-SubCell.::GO:0005874; C:microtubule; IEA:UniProtKB-KW.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0003774; F:motor activity; IEA:UniProtKB-KW.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0006810; P:transport; IEA:UniProtKB-KW.
290Q84NN4    301   CDSP_ORYSJ Thioredoxin-like protein CDSP32, c...960.00004     44.3     30     51
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0016671; F:oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor; IDA:UniProtKB.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0006810; P:transport; IEA:UniProtKB-KW.
291Q9BS26    406   ERP44_HUMAN Endoplasmic reticulum resident pr...830.000002     48.5     30     55GO:0005788; C:endoplasmic reticulum lumen; IDA:UniProtKB.::GO:0005789; C:endoplasmic reticulum membrane; IDA:UniProtKB.::GO:0005793; C:endoplasmic reticulum-Golgi intermediate compartment; IDA:UniProtKB.
GO:0003756; F:protein disulfide isomerase activity; IDA:UniProtKB.
GO:0045454; P:cell redox homeostasis; TAS:UniProtKB.::GO:0009100; P:glycoprotein metabolic process; IDA:UniProtKB.::GO:0006457; P:protein folding; IDA:UniProtKB.::GO:0006986; P:response to unfolded protein; IDA:UniProtKB.
292P12244    508   GSBP_CHICK Dolichyl-diphosphooligosaccharide-...650.0005     41.6     35     55GO:0005788; C:endoplasmic reticulum lumen; IEA:UniProtKB-SubCell.
GO:0004579; F:dolichyl-diphosphooligosaccharide-protein glycotransferase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0016853; F:isomerase activity; IEA:InterPro.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.
293Q5RDG4    505   PDIA3_PONAB Protein disulfide-isomerase A3 OS...650.00002     46.2     37     54GO:0005788; C:endoplasmic reticulum lumen; IEA:UniProtKB-SubCell.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0003756; F:protein disulfide isomerase activity; IEA:EC.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.
294P30101    505   PDIA3_HUMAN Protein disulfide-isomerase A3 OS...650.00002     46.2     37     54GO:0005788; C:endoplasmic reticulum lumen; TAS:Reactome.::GO:0042470; C:melanosome; IEA:UniProtKB-SubCell.::GO:0045335; C:phagocytic vesicle; TAS:Reactome.
GO:0004197; F:cysteine-type endopeptidase activity; TAS:ProtInc.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0004629; F:phospholipase C activity; TAS:ProtInc.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0003756; F:protein disulfide isomerase activity; TAS:ProtInc.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
GO:0002479; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; TAS:Reactome.::GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0043687; P:post-translational protein modification; TAS:Reactome.::GO:0006457; P:protein folding; TAS:Reactome.::GO:0006606; P:protein import into nucleus; TAS:ProtInc.::GO:0018279; P:protein N-linked glycosylation via asparagine; TAS:Reactome.::GO:0006621; P:protein retention in ER lumen; TAS:ProtInc.::GO:0007165; P:signal transduction; TAS:ProtInc.
295Q4VIT4    505   PDIA3_CHLAE Protein disulfide-isomerase A3 OS...650.00002     46.2     37     54GO:0005788; C:endoplasmic reticulum lumen; IEA:UniProtKB-SubCell.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0003756; F:protein disulfide isomerase activity; IEA:EC.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.
296O22229    529   TRXB3_ARATH NADPH-dependent thioredoxin reduc...710.000002     48.5     28     63GO:0009570; C:chloroplast stroma; IDA:TAIR.
GO:0008047; F:enzyme activator activity; IDA:UniProtKB.::GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0016671; F:oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004791; F:thioredoxin-disulfide reductase activity; IDA:UniProtKB.
GO:0045454; P:cell redox homeostasis; IDA:UniProtKB.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0042744; P:hydrogen peroxide catabolic process; IMP:TAIR.::GO:0010380; P:regulation of chlorophyll biosynthetic process; IMP:UniProtKB.::GO:0010581; P:regulation of starch biosynthetic process; IMP:UniProtKB.::GO:0019430; P:removal of superoxide radicals; IEA:InterPro.::GO:0006810; P:transport; IEA:UniProtKB-KW.
297Q9MAU6    447   PDI22_ARATH Protein disulfide-isomerase like ...740.00006     44.3     27     50GO:0005788; C:endoplasmic reticulum lumen; IEA:UniProtKB-SubCell.::GO:0009505; C:plant-type cell wall; IDA:TAIR.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0003756; F:protein disulfide isomerase activity; ISS:TAIR.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0034976; P:response to endoplasmic reticulum stress; IEP:TAIR.
298Q8N427    588   TXND3_HUMAN Thioredoxin domain-containing pro...1020.000003     48.5     24     45GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0015630; C:microtubule cytoskeleton; IDA:HPA.
GO:0005524; F:ATP binding; IEA:InterPro.::GO:0004550; F:nucleoside diphosphate kinase activity; IEA:InterPro.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0006241; P:CTP biosynthetic process; IEA:InterPro.::GO:0006183; P:GTP biosynthetic process; IEA:InterPro.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0007283; P:spermatogenesis; IEA:UniProtKB-KW.::GO:0006228; P:UTP biosynthetic process; IEA:InterPro.
299Q86IA3    363   PDI1_DICDI Protein disulfide-isomerase 1 OS=D...790.00003     45.1     34     51GO:0005788; C:endoplasmic reticulum lumen; IEA:UniProtKB-SubCell.::GO:0042175; C:nuclear outer membrane-endoplasmic reticulum membrane network; IDA:dictyBase.::GO:0045335; C:phagocytic vesicle; IDA:dictyBase.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0003756; F:protein disulfide isomerase activity; IGI:dictyBase.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0006457; P:protein folding; ISS:dictyBase.
300Q5R5L3    793   DJC10_PONAB DnaJ homolog subfamily C member 1...580.89     31.6     22     47GO:0005788; C:endoplasmic reticulum lumen; IEA:UniProtKB-SubCell.::GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0031072; F:heat shock protein binding; IEA:InterPro.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.::GO:0051082; F:unfolded protein binding; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0006457; P:protein folding; IEA:InterPro.
301Q8IXB1    793   DJC10_HUMAN DnaJ homolog subfamily C member 1...580.89     31.6     22     47GO:0034663; C:endoplasmic reticulum chaperone complex; IDA:UniProtKB.::GO:0005788; C:endoplasmic reticulum lumen; IEA:UniProtKB-SubCell.::GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
GO:0001671; F:ATPase activator activity; ISS:UniProtKB.::GO:0051117; F:ATPase binding; IPI:UniProtKB.::GO:0051087; F:chaperone binding; IDA:UniProtKB.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0031072; F:heat shock protein binding; IEA:InterPro.::GO:0051787; F:misfolded protein binding; IDA:UniProtKB.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.::GO:0051082; F:unfolded protein binding; IEA:InterPro.
GO:0070059; P:apoptosis in response to endoplasmic reticulum stress; IDA:UniProtKB.::GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0030433; P:ER-associated protein catabolic process; IMP:UniProtKB.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0001933; P:negative regulation of protein phosphorylation; IDA:UniProtKB.::GO:0006457; P:protein folding; IEA:InterPro.::GO:0034976; P:response to endoplasmic reticulum stress; IDA:UniProtKB.
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