Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YGR206W
Length:
101
Number of sequences:
5887
Description:
YGR206W MVB12 SGDID:S000003438, Chr VII from 910432-910737, Genome Release 64-1-1, Verified ORF, "ESCRT-I subunit required to stabilize oligomers of the ESCRT-I core complex (Stp22p, Vps28p, Srn2p), which is involved in ubiquitin-dependent sorting of proteins into the endosome; deletion mutant is sensitive to rapamycin and nystatin"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
1P42939    101   MVB12_YEAST Multivesicular body sorting facto...1013e-70     211     100     100GO:0005829; C:cytosol; IDA:SGD.::GO:0000813; C:ESCRT I complex; IDA:SGD.::GO:0031902; C:late endosome membrane; IEA:UniProtKB-SubCell.
GO:0043130; F:ubiquitin binding; IDA:SGD.
GO:0032509; P:endosome transport via multivesicular body sorting pathway; IC:SGD.::GO:0031333; P:negative regulation of protein complex assembly; IMP:SGD.::GO:0006623; P:protein targeting to vacuole; IMP:SGD.
2Q28BL7    757   PO2F1_XENTR POU domain, class 2, transcriptio...500.11     34.3     32     48GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005667; C:transcription factor complex; ISS:UniProtKB.
GO:0043565; F:sequence-specific DNA binding; ISS:UniProtKB.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0007219; P:Notch signaling pathway; ISS:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0060019; P:radial glial cell differentiation; ISS:UniProtKB.::GO:0042981; P:regulation of apoptotic process; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
3P16143    758   PO2F1_XENLA POU domain, class 2, transcriptio...500.18     33.5     32     48GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0005667; C:transcription factor complex; ISS:UniProtKB.
GO:0043565; F:sequence-specific DNA binding; IDA:UniProtKB.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0007219; P:Notch signaling pathway; IMP:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0060019; P:radial glial cell differentiation; IMP:UniProtKB.::GO:0042981; P:regulation of apoptotic process; IMP:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
4P31369    498   PDM2A_DROME POU domain protein 2, isoform A O...720.39     32.7     28     42GO:0005634; C:nucleus; IC:UniProtKB.
GO:0001077; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; IDA:FlyBase.::GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
GO:0007417; P:central nervous system development; IMP:UniProtKB.::GO:0007398; P:ectoderm development; IMP:UniProtKB.::GO:0014019; P:neuroblast development; IMP:FlyBase.
5P20913    105   HM19_XENLA Homeotic protein NRL-19 OS=Xenopus...480.42     31.6     31     48GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
6P20263    352   PO5F1_MOUSE POU domain, class 5, transcriptio...480.43     32.3     35     54GO:0005737; C:cytoplasm; IDA:MGI.::GO:0005625; C:soluble fraction; IDA:MGI.::GO:0005667; C:transcription factor complex; IDA:MGI.::GO:0017053; C:transcriptional repressor complex; IDA:MGI.
GO:0003682; F:chromatin binding; IDA:MGI.::GO:0043565; F:sequence-specific DNA binding; IDA:MGI.::GO:0000981; F:sequence-specific DNA binding RNA polymerase II transcription factor activity; IDA:BHF-UCL.::GO:0003714; F:transcription corepressor activity; IDA:MGI.::GO:0008134; F:transcription factor binding; IPI:UniProtKB.::GO:0044212; F:transcription regulatory region DNA binding; IDA:UniProtKB.::GO:0031625; F:ubiquitin protein ligase binding; IPI:BHF-UCL.
GO:0001712; P:ectodermal cell fate commitment; IDA:MGI.::GO:0001711; P:endodermal cell fate commitment; IDA:MGI.::GO:0030718; P:germ-line stem cell maintenance; IMP:MGI.::GO:0001710; P:mesodermal cell fate commitment; IDA:MGI.::GO:0042789; P:mRNA transcription from RNA polymerase II promoter; IDA:BHF-UCL.::GO:0045955; P:negative regulation of calcium ion-dependent exocytosis; IDA:MGI.::GO:0045892; P:negative regulation of transcription, DNA-dependent; IDA:MGI.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:MGI.::GO:0009786; P:regulation of asymmetric cell division; IEP:BHF-UCL.::GO:0032526; P:response to retinoic acid; IDA:MGI.::GO:0001829; P:trophectodermal cell differentiation; IGI:MGI.
7P20914    105   PO3F3_XENLA POU domain, class 3, transcriptio...470.54     31.2     32     47GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
8Q29087    131   PO3F3_PIG POU domain, class 3, transcription ...470.6     31.6     32     47GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0043565; F:sequence-specific DNA binding; ISS:UniProtKB.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
GO:0072218; P:metanephric ascending thin limb development; ISS:UniProtKB.::GO:0072240; P:metanephric DCT cell differentiation; ISS:UniProtKB.::GO:0072227; P:metanephric macula densa development; ISS:UniProtKB.::GO:0072233; P:metanephric thick ascending limb development; ISS:UniProtKB.::GO:0043066; P:negative regulation of apoptotic process; ISS:UniProtKB.::GO:0045892; P:negative regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0007399; P:nervous system development; IEA:UniProtKB-KW.::GO:0008284; P:positive regulation of cell proliferation; ISS:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
9Q06416    359   P5F1B_HUMAN Putative POU domain, class 5, tra...480.68     32     33     54GO:0005634; C:nucleus; TAS:UniProtKB.
GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:UniProtKB.
GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
10Q9DAC9    329   PO5F2_MOUSE POU domain, class 5, transcriptio...480.7     32     33     52GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
11Q9VK71    893   PDM2B_DROME POU domain protein 2, isoform B O...720.77     32     28     40GO:0005634; C:nucleus; IMP:UniProtKB.
GO:0001077; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; IDA:FlyBase.::GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
GO:0007417; P:central nervous system development; IMP:UniProtKB.::GO:0007398; P:ectoderm development; IMP:UniProtKB.::GO:0014019; P:neuroblast development; IMP:FlyBase.
12Q9NQV6    1147   PRD10_HUMAN PR domain zinc finger protein 10 ...780.8     31.6     29     45GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
13Q5RAX9    1117   PRD10_PONAB PR domain zinc finger protein 10 ...780.84     31.6     29     45GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
14P56225    335   PO5F2_RAT POU domain, class 5, transcription ...480.94     31.6     33     52GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0007126; P:meiosis; IEA:UniProtKB-KW.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0007283; P:spermatogenesis; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
15Q7YR49    360   PO5F1_PANTR POU domain, class 5, transcriptio...480.95     31.6     33     52GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
16Q01860    360   PO5F1_HUMAN POU domain, class 5, transcriptio...480.95     31.6     33     52GO:0005829; C:cytosol; IDA:UniProtKB.::GO:0005654; C:nucleoplasm; IDA:BHF-UCL.::GO:0005667; C:transcription factor complex; IDA:BHF-UCL.
GO:0035198; F:miRNA binding; IDA:UniProtKB.::GO:0043565; F:sequence-specific DNA binding; IDA:MGI.::GO:0000981; F:sequence-specific DNA binding RNA polymerase II transcription factor activity; ISS:BHF-UCL.::GO:0008134; F:transcription factor binding; IPI:BHF-UCL.::GO:0044212; F:transcription regulatory region DNA binding; IDA:BHF-UCL.::GO:0031625; F:ubiquitin protein ligase binding; IPI:BHF-UCL.
GO:0001824; P:blastocyst development; ISS:BHF-UCL.::GO:0003130; P:BMP signaling pathway involved in heart induction; IMP:BHF-UCL.::GO:0060913; P:cardiac cell fate determination; IDA:BHF-UCL.::GO:0060795; P:cell fate commitment involved in formation of primary germ layers; IMP:BHF-UCL.::GO:0001714; P:endodermal cell fate specification; IDA:MGI.::GO:0042789; P:mRNA transcription from RNA polymerase II promoter; ISS:BHF-UCL.::GO:0060965; P:negative regulation of gene silencing by miRNA; IMP:UniProtKB.::GO:0035413; P:positive regulation of catenin import into nucleus; IDA:BHF-UCL.::GO:0060391; P:positive regulation of SMAD protein import into nucleus; IDA:BHF-UCL.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:MGI.::GO:0009786; P:regulation of asymmetric cell division; ISS:BHF-UCL.::GO:0090081; P:regulation of heart induction by regulation of canonical Wnt receptor signaling pathway; IMP:BHF-UCL.::GO:0090308; P:regulation of methylation-dependent chromatin silencing; IDA:BHF-UCL.::GO:0009611; P:response to wounding; IEP:UniProtKB.::GO:0035019; P:somatic stem cell maintenance; IDA:UniProtKB.
17Q5TM49    360   PO5F1_MACMU POU domain, class 5, transcriptio...481.1     31.2     33     52
18A2BID7    1121   PRD10_DANRE PR domain zinc finger protein 10 ...781.2     31.2     29     46GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
19Q9TSV5    360   PO5F1_PIG POU domain, class 5, transcription ...481.2     31.2     33     52
20O97552    360   PO5F1_BOVIN POU domain, class 5, transcriptio...481.3     31.2     33     52GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
21P56224    438   P3F3A_DANRE POU domain, class 3, transcriptio...411.7     30.8     34     49GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
22Q24705    471   PDM2_DROVI POU domain protein 2 OS=Drosophila...721.8     30.8     28     43GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
23P16241    427   CF1A_DROME POU domain protein CF1A OS=Drosoph...411.9     30.8     34     49GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0001077; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; IDA:FlyBase.::GO:0000980; F:RNA polymerase II distal enhancer sequence-specific DNA binding; IDA:FlyBase.
GO:0035284; P:brain segmentation; IMP:FlyBase.::GO:0048813; P:dendrite morphogenesis; TAS:FlyBase.::GO:0007425; P:epithelial cell fate determination, open tracheal system; TAS:FlyBase.::GO:0008045; P:motor axon guidance; IMP:FlyBase.::GO:0007422; P:peripheral nervous system development; IMP:FlyBase.::GO:0048814; P:regulation of dendrite morphogenesis; IMP:FlyBase.
24P20268    380   HM06_CAEEL Homeobox protein ceh-6 OS=Caenorha...472.2     30.4     32     47GO:0005737; C:cytoplasm; IDA:WormBase.::GO:0005634; C:nucleus; IDA:WormBase.::GO:0005625; C:soluble fraction; IDA:WormBase.
GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
GO:0010171; P:body morphogenesis; IMP:WormBase.::GO:0030154; P:cell differentiation; IMP:WormBase.::GO:0007588; P:excretion; IMP:WormBase.::GO:0040007; P:growth; IMP:WormBase.::GO:0040011; P:locomotion; IMP:WormBase.::GO:0018996; P:molting cycle, collagen and cuticulin-based cuticle; IMP:WormBase.::GO:0002119; P:nematode larval development; IMP:WormBase.::GO:0040010; P:positive regulation of growth rate; IMP:WormBase.::GO:0000003; P:reproduction; IMP:WormBase.::GO:0030104; P:water homeostasis; IMP:WormBase.
25Q29076    745   PO2F1_PIG POU domain, class 2, transcription ...412.2     30.4     29     51GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
26B4F6U4    1173   PRD10_XENTR PR domain zinc finger protein 10 ...782.5     30.4     28     46GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
27P79745    443   P3F3B_DANRE POU domain, class 3, transcriptio...412.5     30.4     34     49GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
28P20264    500   PO3F3_HUMAN POU domain, class 3, transcriptio...412.5     30.4     34     49GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0043565; F:sequence-specific DNA binding; ISS:UniProtKB.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.
GO:0072218; P:metanephric ascending thin limb development; ISS:UniProtKB.::GO:0072240; P:metanephric DCT cell differentiation; ISS:UniProtKB.::GO:0072227; P:metanephric macula densa development; ISS:UniProtKB.::GO:0072233; P:metanephric thick ascending limb development; ISS:UniProtKB.::GO:0043066; P:negative regulation of apoptotic process; ISS:UniProtKB.::GO:0045892; P:negative regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0008284; P:positive regulation of cell proliferation; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
29Q63262    497   PO3F3_RAT POU domain, class 3, transcription ...412.6     30.4     34     49GO:0005634; C:nucleus; IMP:UniProtKB.
GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; IDA:MGI.::GO:0043565; F:sequence-specific DNA binding; ISS:UniProtKB.
GO:0072218; P:metanephric ascending thin limb development; ISS:UniProtKB.::GO:0072240; P:metanephric DCT cell differentiation; ISS:UniProtKB.::GO:0072227; P:metanephric macula densa development; ISS:UniProtKB.::GO:0072233; P:metanephric thick ascending limb development; ISS:UniProtKB.::GO:0043066; P:negative regulation of apoptotic process; ISS:UniProtKB.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IGI:MGI.::GO:0007399; P:nervous system development; IEA:UniProtKB-KW.::GO:0008284; P:positive regulation of cell proliferation; ISS:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:RGD.
30A1L0Z1    360   PO3F4_XENTR POU domain, class 3, transcriptio...472.6     30     32     47GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
31P31361    497   PO3F3_MOUSE POU domain, class 3, transcriptio...412.6     30     34     49GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0071837; F:HMG box domain binding; IPI:UniProtKB.::GO:0043565; F:sequence-specific DNA binding; IDA:UniProtKB.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
GO:0021799; P:cerebral cortex radially oriented cell migration; IGI:MGI.::GO:0021869; P:forebrain ventricular zone progenitor cell division; IGI:MGI.::GO:0072218; P:metanephric ascending thin limb development; IMP:UniProtKB.::GO:0072240; P:metanephric DCT cell differentiation; IMP:UniProtKB.::GO:0072227; P:metanephric macula densa development; IMP:UniProtKB.::GO:0072233; P:metanephric thick ascending limb development; IMP:UniProtKB.::GO:0043066; P:negative regulation of apoptotic process; IMP:UniProtKB.::GO:0045892; P:negative regulation of transcription, DNA-dependent; IDA:UniProtKB.::GO:0008284; P:positive regulation of cell proliferation; IMP:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IGI:MGI.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
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