UniProt_SwissProt BLAST: Single locus

Species:

Saccharomyces cerevisiae S288C

Locus:

YGR204W

Length:

946

Number of sequences:

5887

Description:

YGR204W ADE3 SGDID:S000003436, Chr VII from 905934-908774, Genome Release 64-1-1, Verified ORF, "Cytoplasmic trifunctional enzyme C1-tetrahydrofolate synthase, involved in single carbon metabolism and required for biosynthesis of purines, thymidylate, methionine, and histidine; null mutation causes auxotrophy for adenine and histidine"

rec.	Subject	Hit Length	Description	Align.Len	E value	Bit score	% ident.	% pos.	GO associations
301	Q97CL3	536	FTHS_THEVO Formate--tetrahydrofolate ligase O...	613	4e-115	370	40	55
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004329; F:formate-tetrahydrofolate ligase activity; IEA:EC.
									GO:0009396; P:folic acid-containing compound biosynthetic process; IEA:InterPro.::GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW.
302	A0PXN0	556	FTHS_CLONN Formate--tetrahydrofolate ligase O...	628	6e-115	370	36	54
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004329; F:formate-tetrahydrofolate ligase activity; IEA:EC.
									GO:0009396; P:folic acid-containing compound biosynthetic process; IEA:InterPro.::GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW.
303	A1SQH3	559	FTHS_NOCSJ Formate--tetrahydrofolate ligase O...	628	2e-114	369	38	54
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004329; F:formate-tetrahydrofolate ligase activity; IEA:EC.
									GO:0009396; P:folic acid-containing compound biosynthetic process; IEA:InterPro.::GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW.
304	Q9HI67	536	FTHS_THEAC Formate--tetrahydrofolate ligase O...	613	2e-114	368	39	55
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004329; F:formate-tetrahydrofolate ligase activity; IEA:EC.
									GO:0009396; P:folic acid-containing compound biosynthetic process; IEA:InterPro.::GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW.
305	Q160C2	558	FTHS_ROSDO Formate--tetrahydrofolate ligase O...	148	1e-33	140	51	73
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004329; F:formate-tetrahydrofolate ligase activity; IEA:EC.
									GO:0009396; P:folic acid-containing compound biosynthetic process; IEA:InterPro.::GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW.
306	Q72GY9	543	FTHS_THET2 Formate--tetrahydrofolate ligase O...	611	7e-111	359	39	55
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004329; F:formate-tetrahydrofolate ligase activity; IEA:EC.
									GO:0009396; P:folic acid-containing compound biosynthetic process; IEA:InterPro.::GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW.
307	Q5FJY2	558	FTHS1_LACAC Formate--tetrahydrofolate ligase ...	630	4e-109	355	37	56
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004329; F:formate-tetrahydrofolate ligase activity; IEA:EC.
									GO:0009396; P:folic acid-containing compound biosynthetic process; IEA:InterPro.::GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW.
308	Q8RHF4	544	FTHS_FUSNN Formate--tetrahydrofolate ligase O...	630	3e-107	349	37	52
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004329; F:formate-tetrahydrofolate ligase activity; IEA:EC.
									GO:0009396; P:folic acid-containing compound biosynthetic process; IEA:InterPro.::GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW.
309	Q6KZM3	535	FTHS_PICTO Formate--tetrahydrofolate ligase O...	596	4e-106	346	36	55
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004329; F:formate-tetrahydrofolate ligase activity; IEA:EC.
									GO:0009396; P:folic acid-containing compound biosynthetic process; IEA:InterPro.::GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW.
310	A9NE95	527	FTHS_ACHLI Formate--tetrahydrofolate ligase O...	607	6e-105	342	38	53
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004329; F:formate-tetrahydrofolate ligase activity; IEA:EC.
									GO:0009396; P:folic acid-containing compound biosynthetic process; IEA:InterPro.::GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW.
311	Q9PQS1	521	FTHS_UREPA Formate--tetrahydrofolate ligase O...	597	7e-87	293	34	52
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004329; F:formate-tetrahydrofolate ligase activity; IEA:EC.
									GO:0009396; P:folic acid-containing compound biosynthetic process; IEA:InterPro.::GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW.
312	Q73RS2	293	FOLD_TREDE Bifunctional protein FolD OS=Trepo...	301	1e-78	263	45	64
									GO:0004477; F:methenyltetrahydrofolate cyclohydrolase activity; IEA:EC.::GO:0004488; F:methylenetetrahydrofolate dehydrogenase (NADP+) activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro.
									GO:0009396; P:folic acid-containing compound biosynthetic process; IEA:InterPro.::GO:0000105; P:histidine biosynthetic process; IEA:UniProtKB-KW.::GO:0009086; P:methionine biosynthetic process; IEA:UniProtKB-KW.::GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW.::GO:0006164; P:purine nucleotide biosynthetic process; IEA:UniProtKB-KW.
313	Q2RIB4	280	FOLD_MOOTA Bifunctional protein FolD OS=Moore...	298	1e-78	263	46	63
									GO:0004477; F:methenyltetrahydrofolate cyclohydrolase activity; IEA:EC.::GO:0004488; F:methylenetetrahydrofolate dehydrogenase (NADP+) activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro.
									GO:0009396; P:folic acid-containing compound biosynthetic process; IEA:InterPro.::GO:0000105; P:histidine biosynthetic process; IEA:UniProtKB-KW.::GO:0009086; P:methionine biosynthetic process; IEA:UniProtKB-KW.::GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW.::GO:0006164; P:purine nucleotide biosynthetic process; IEA:UniProtKB-KW.
314	Q92BZ4	284	FOLD_LISIN Bifunctional protein FolD OS=Liste...	298	1e-76	258	47	64
									GO:0004477; F:methenyltetrahydrofolate cyclohydrolase activity; IEA:EC.::GO:0004488; F:methylenetetrahydrofolate dehydrogenase (NADP+) activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro.
									GO:0009396; P:folic acid-containing compound biosynthetic process; IEA:InterPro.::GO:0000105; P:histidine biosynthetic process; IEA:UniProtKB-KW.::GO:0009086; P:methionine biosynthetic process; IEA:UniProtKB-KW.::GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW.::GO:0006164; P:purine nucleotide biosynthetic process; IEA:UniProtKB-KW.
315	B9EAY2	282	FOLD_MACCJ Bifunctional protein FolD OS=Macro...	301	2e-76	257	44	64
									GO:0004477; F:methenyltetrahydrofolate cyclohydrolase activity; IEA:EC.::GO:0004488; F:methylenetetrahydrofolate dehydrogenase (NADP+) activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro.
									GO:0009396; P:folic acid-containing compound biosynthetic process; IEA:InterPro.::GO:0000105; P:histidine biosynthetic process; IEA:UniProtKB-KW.::GO:0009086; P:methionine biosynthetic process; IEA:UniProtKB-KW.::GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW.::GO:0006164; P:purine nucleotide biosynthetic process; IEA:UniProtKB-KW.
316	C1L2R6	284	FOLD_LISMC Bifunctional protein FolD OS=Liste...	296	2e-76	257	46	64
									GO:0004477; F:methenyltetrahydrofolate cyclohydrolase activity; IEA:EC.::GO:0004488; F:methylenetetrahydrofolate dehydrogenase (NADP+) activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro.
									GO:0009396; P:folic acid-containing compound biosynthetic process; IEA:InterPro.::GO:0000105; P:histidine biosynthetic process; IEA:UniProtKB-KW.::GO:0009086; P:methionine biosynthetic process; IEA:UniProtKB-KW.::GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW.::GO:0006164; P:purine nucleotide biosynthetic process; IEA:UniProtKB-KW.
317	B8DFW8	284	FOLD_LISMH Bifunctional protein FolD OS=Liste...	296	3e-76	256	46	64
									GO:0004477; F:methenyltetrahydrofolate cyclohydrolase activity; IEA:EC.::GO:0004488; F:methylenetetrahydrofolate dehydrogenase (NADP+) activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro.
									GO:0009396; P:folic acid-containing compound biosynthetic process; IEA:InterPro.::GO:0000105; P:histidine biosynthetic process; IEA:UniProtKB-KW.::GO:0009086; P:methionine biosynthetic process; IEA:UniProtKB-KW.::GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW.::GO:0006164; P:purine nucleotide biosynthetic process; IEA:UniProtKB-KW.
318	Q8Y7C5	284	FOLD_LISMO Bifunctional protein FolD OS=Liste...	296	3e-76	256	46	64
									GO:0004477; F:methenyltetrahydrofolate cyclohydrolase activity; IEA:EC.::GO:0004488; F:methylenetetrahydrofolate dehydrogenase (NADP+) activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro.
									GO:0009396; P:folic acid-containing compound biosynthetic process; IEA:InterPro.::GO:0000105; P:histidine biosynthetic process; IEA:UniProtKB-KW.::GO:0009086; P:methionine biosynthetic process; IEA:UniProtKB-KW.::GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW.::GO:0006164; P:purine nucleotide biosynthetic process; IEA:UniProtKB-KW.
319	A8FF15	283	FOLD_BACP2 Bifunctional protein FolD OS=Bacil...	300	4e-76	256	46	63
									GO:0004477; F:methenyltetrahydrofolate cyclohydrolase activity; IEA:EC.::GO:0004488; F:methylenetetrahydrofolate dehydrogenase (NADP+) activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro.
									GO:0009396; P:folic acid-containing compound biosynthetic process; IEA:InterPro.::GO:0000105; P:histidine biosynthetic process; IEA:UniProtKB-KW.::GO:0009086; P:methionine biosynthetic process; IEA:UniProtKB-KW.::GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW.::GO:0006164; P:purine nucleotide biosynthetic process; IEA:UniProtKB-KW.
320	Q8EUQ1	530	FTHS_MYCPE Formate--tetrahydrofolate ligase O...	579	5e-76	264	31	48
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004329; F:formate-tetrahydrofolate ligase activity; IEA:EC.
									GO:0009396; P:folic acid-containing compound biosynthetic process; IEA:InterPro.::GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW.
321	A7Z6J9	283	FOLD_BACA2 Bifunctional protein FolD OS=Bacil...	300	5e-76	256	44	63
									GO:0004477; F:methenyltetrahydrofolate cyclohydrolase activity; IEA:EC.::GO:0004488; F:methylenetetrahydrofolate dehydrogenase (NADP+) activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro.
									GO:0009396; P:folic acid-containing compound biosynthetic process; IEA:InterPro.::GO:0000105; P:histidine biosynthetic process; IEA:UniProtKB-KW.::GO:0009086; P:methionine biosynthetic process; IEA:UniProtKB-KW.::GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW.::GO:0006164; P:purine nucleotide biosynthetic process; IEA:UniProtKB-KW.
322	A5GAM5	280	FOLD_GEOUR Bifunctional protein FolD OS=Geoba...	296	6e-76	255	45	61
									GO:0004477; F:methenyltetrahydrofolate cyclohydrolase activity; IEA:EC.::GO:0004488; F:methylenetetrahydrofolate dehydrogenase (NADP+) activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro.
									GO:0009396; P:folic acid-containing compound biosynthetic process; IEA:InterPro.::GO:0000105; P:histidine biosynthetic process; IEA:UniProtKB-KW.::GO:0009086; P:methionine biosynthetic process; IEA:UniProtKB-KW.::GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW.::GO:0006164; P:purine nucleotide biosynthetic process; IEA:UniProtKB-KW.
323	Q71ZW2	284	FOLD_LISMF Bifunctional protein FolD OS=Liste...	296	6e-76	256	46	64
									GO:0004477; F:methenyltetrahydrofolate cyclohydrolase activity; IEA:EC.::GO:0004488; F:methylenetetrahydrofolate dehydrogenase (NADP+) activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro.
									GO:0009396; P:folic acid-containing compound biosynthetic process; IEA:InterPro.::GO:0000105; P:histidine biosynthetic process; IEA:UniProtKB-KW.::GO:0009086; P:methionine biosynthetic process; IEA:UniProtKB-KW.::GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW.::GO:0006164; P:purine nucleotide biosynthetic process; IEA:UniProtKB-KW.
324	B9M769	280	FOLD_GEOSF Bifunctional protein FolD OS=Geoba...	296	7e-76	255	45	61
									GO:0004477; F:methenyltetrahydrofolate cyclohydrolase activity; IEA:EC.::GO:0004488; F:methylenetetrahydrofolate dehydrogenase (NADP+) activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro.
									GO:0009396; P:folic acid-containing compound biosynthetic process; IEA:InterPro.::GO:0000105; P:histidine biosynthetic process; IEA:UniProtKB-KW.::GO:0009086; P:methionine biosynthetic process; IEA:UniProtKB-KW.::GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW.::GO:0006164; P:purine nucleotide biosynthetic process; IEA:UniProtKB-KW.
325	Q65HI8	284	FOLD_BACLD Bifunctional protein FolD OS=Bacil...	301	8e-76	255	45	62
									GO:0004477; F:methenyltetrahydrofolate cyclohydrolase activity; IEA:EC.::GO:0004488; F:methylenetetrahydrofolate dehydrogenase (NADP+) activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro.
									GO:0009396; P:folic acid-containing compound biosynthetic process; IEA:InterPro.::GO:0000105; P:histidine biosynthetic process; IEA:UniProtKB-KW.::GO:0009086; P:methionine biosynthetic process; IEA:UniProtKB-KW.::GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW.::GO:0006164; P:purine nucleotide biosynthetic process; IEA:UniProtKB-KW.
326	Q2RWY4	296	FOLD_RHORT Bifunctional protein FolD OS=Rhodo...	300	2e-75	254	47	61
									GO:0004477; F:methenyltetrahydrofolate cyclohydrolase activity; IEA:EC.::GO:0004488; F:methylenetetrahydrofolate dehydrogenase (NADP+) activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro.
									GO:0009396; P:folic acid-containing compound biosynthetic process; IEA:InterPro.::GO:0000105; P:histidine biosynthetic process; IEA:UniProtKB-KW.::GO:0009086; P:methionine biosynthetic process; IEA:UniProtKB-KW.::GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW.::GO:0006164; P:purine nucleotide biosynthetic process; IEA:UniProtKB-KW.
327	P54382	283	FOLD_BACSU Bifunctional protein FolD OS=Bacil...	300	2e-75	254	45	61
									GO:0004477; F:methenyltetrahydrofolate cyclohydrolase activity; IEA:EC.::GO:0004488; F:methylenetetrahydrofolate dehydrogenase (NADP+) activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro.
									GO:0009396; P:folic acid-containing compound biosynthetic process; IEA:InterPro.::GO:0000105; P:histidine biosynthetic process; IEA:UniProtKB-KW.::GO:0009086; P:methionine biosynthetic process; IEA:UniProtKB-KW.::GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW.::GO:0006164; P:purine nucleotide biosynthetic process; IEA:UniProtKB-KW.
328	C0ZC05	284	FOLD_BREBN Bifunctional protein FolD OS=Brevi...	302	4e-75	253	46	62
									GO:0004477; F:methenyltetrahydrofolate cyclohydrolase activity; IEA:EC.::GO:0004488; F:methylenetetrahydrofolate dehydrogenase (NADP+) activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro.
									GO:0009396; P:folic acid-containing compound biosynthetic process; IEA:InterPro.::GO:0000105; P:histidine biosynthetic process; IEA:UniProtKB-KW.::GO:0009086; P:methionine biosynthetic process; IEA:UniProtKB-KW.::GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW.::GO:0006164; P:purine nucleotide biosynthetic process; IEA:UniProtKB-KW.
329	Q39WH4	285	FOLD2_GEOMG Bifunctional protein FolD 2 OS=Ge...	297	6e-75	253	47	61
									GO:0004477; F:methenyltetrahydrofolate cyclohydrolase activity; IEA:EC.::GO:0004488; F:methylenetetrahydrofolate dehydrogenase (NADP+) activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro.
									GO:0009396; P:folic acid-containing compound biosynthetic process; IEA:InterPro.::GO:0000105; P:histidine biosynthetic process; IEA:UniProtKB-KW.::GO:0009086; P:methionine biosynthetic process; IEA:UniProtKB-KW.::GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW.::GO:0006164; P:purine nucleotide biosynthetic process; IEA:UniProtKB-KW.
330	Q49WI7	285	FOLD_STAS1 Bifunctional protein FolD OS=DSM 2...	297	2e-74	251	44	64
									GO:0004477; F:methenyltetrahydrofolate cyclohydrolase activity; IEA:EC.::GO:0004488; F:methylenetetrahydrofolate dehydrogenase (NADP+) activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro.
									GO:0009396; P:folic acid-containing compound biosynthetic process; IEA:InterPro.::GO:0000105; P:histidine biosynthetic process; IEA:UniProtKB-KW.::GO:0009086; P:methionine biosynthetic process; IEA:UniProtKB-KW.::GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW.::GO:0006164; P:purine nucleotide biosynthetic process; IEA:UniProtKB-KW.
331	Q74EU7	285	FOLD2_GEOSL Bifunctional protein FolD 2 OS=Ge...	293	3e-74	251	46	62
									GO:0004477; F:methenyltetrahydrofolate cyclohydrolase activity; IEA:EC.::GO:0004488; F:methylenetetrahydrofolate dehydrogenase (NADP+) activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro.
									GO:0009396; P:folic acid-containing compound biosynthetic process; IEA:InterPro.::GO:0000105; P:histidine biosynthetic process; IEA:UniProtKB-KW.::GO:0009086; P:methionine biosynthetic process; IEA:UniProtKB-KW.::GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW.::GO:0006164; P:purine nucleotide biosynthetic process; IEA:UniProtKB-KW.

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