Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YGR195W
Length:
246
Number of sequences:
5887
Description:
YGR195W SKI6 SGDID:S000003427, Chr VII from 888882-889622, Genome Release 64-1-1, Verified ORF, "Exosome non-catalytic core component; involved in 3'-5' RNA processing and degradation in both the nucleus and the cytoplasm; has similarity to E. coli RNase PH and to human hRrp41p (EXOSC4)"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
1P46948    246   RRP41_YEAST Exosome complex component SKI6 OS...2466e-179     498     100     100GO:0000177; C:cytoplasmic exosome (RNase complex); IDA:SGD.::GO:0000176; C:nuclear exosome (RNase complex); IDA:SGD.::GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
GO:0005515; F:protein binding; IPI:IntAct.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
GO:0000467; P:exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); IMP:SGD.::GO:0070651; P:nonfunctional rRNA decay; IC:SGD.::GO:0071028; P:nuclear mRNA surveillance; IMP:SGD.::GO:0071039; P:nuclear polyadenylation-dependent CUT catabolic process; IMP:SGD.::GO:0071042; P:nuclear polyadenylation-dependent mRNA catabolic process; IC:SGD.::GO:0071038; P:nuclear polyadenylation-dependent tRNA catabolic process; IDA:SGD.::GO:0070478; P:nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay; IMP:SGD.::GO:0070481; P:nuclear-transcribed mRNA catabolic process, non-stop decay; IC:SGD.::GO:0071051; P:polyadenylation-dependent snoRNA 3'-end processing; IMP:SGD.::GO:0034473; P:U1 snRNA 3'-end processing; IMP:SGD.::GO:0034475; P:U4 snRNA 3'-end processing; IMP:SGD.::GO:0034476; P:U5 snRNA 3'-end processing; IMP:SGD.
2O42872    242   RRP41_SCHPO Exosome complex component ski6 OS...2442e-58     192     39     63GO:0000177; C:cytoplasmic exosome (RNase complex); ISS:PomBase.::GO:0005829; C:cytosol; IDA:PomBase.::GO:0000176; C:nuclear exosome (RNase complex); ISS:PomBase.::GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.::GO:0005816; C:spindle pole body; IDA:PomBase.
GO:0000175; F:3'-5'-exoribonuclease activity; ISS:PomBase.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
GO:0000467; P:exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); ISS:PomBase.::GO:0070651; P:nonfunctional rRNA decay; ISS:PomBase.::GO:0071042; P:nuclear polyadenylation-dependent mRNA catabolic process; ISS:PomBase.::GO:0071035; P:nuclear polyadenylation-dependent rRNA catabolic process; ISS:PomBase.::GO:0071038; P:nuclear polyadenylation-dependent tRNA catabolic process; ISS:PomBase.::GO:0070478; P:nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay; ISS:PomBase.::GO:0070481; P:nuclear-transcribed mRNA catabolic process, non-stop decay; ISS:PomBase.
3Q921I9    245   EXOS4_MOUSE Exosome complex component RRP41 O...2407e-46     159     36     58GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0000178; C:exosome (RNase complex); ISS:UniProtKB.::GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
GO:0005515; F:protein binding; IPI:MGI.
GO:0071044; P:histone mRNA catabolic process; ISS:UniProtKB.
4Q9NPD3    245   EXOS4_HUMAN Exosome complex component RRP41 O...2376e-45     157     36     57GO:0005829; C:cytosol; TAS:Reactome.::GO:0000178; C:exosome (RNase complex); IDA:UniProtKB.::GO:0005730; C:nucleolus; NAS:UniProtKB.::GO:0035327; C:transcriptionally active chromatin; IMP:UniProtKB.
GO:0000175; F:3'-5'-exoribonuclease activity; NAS:UniProtKB.::GO:0017091; F:AU-rich element binding; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0051607; P:defense response to virus; IMP:MGI.::GO:0045006; P:DNA deamination; IDA:UniProtKB.::GO:0043928; P:exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay; TAS:Reactome.::GO:0071044; P:histone mRNA catabolic process; IMP:UniProtKB.::GO:0000460; P:maturation of 5.8S rRNA; IMP:UniProtKB.::GO:0071028; P:nuclear mRNA surveillance; IMP:UniProtKB.::GO:0030307; P:positive regulation of cell growth; IMP:UniProtKB.
5Q7YRA3    245   EXOS4_BOVIN Exosome complex component RRP41 O...2401e-44     155     35     58GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0000178; C:exosome (RNase complex); ISS:UniProtKB.::GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
GO:0004527; F:exonuclease activity; IEA:UniProtKB-KW.
GO:0071044; P:histone mRNA catabolic process; ISS:UniProtKB.
6O29757    258   ECX1_ARCFU Probable exosome complex exonuclea...2335e-33     125     34     55GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0000178; C:exosome (RNase complex); IEA:UniProtKB-KW.
GO:0016896; F:exoribonuclease activity, producing 5'-phosphomonoesters; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:InterPro.
GO:0006396; P:RNA processing; IEA:InterPro.
7Q17533    240   EXOS4_CAEEL Putative exosome complex componen...2332e-30     118     30     54GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0000178; C:exosome (RNase complex); IEA:UniProtKB-KW.::GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
GO:0010171; P:body morphogenesis; IMP:WormBase.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0008406; P:gonad development; IMP:WormBase.::GO:0040007; P:growth; IMP:WormBase.::GO:0002119; P:nematode larval development; IMP:WormBase.::GO:0040010; P:positive regulation of growth rate; IMP:WormBase.::GO:0040018; P:positive regulation of multicellular organism growth; IMP:WormBase.::GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
8A9A5C9    244   ECX1_NITMS Probable exosome complex exonuclea...2233e-30     118     34     53GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0000178; C:exosome (RNase complex); IEA:UniProtKB-KW.
GO:0016896; F:exoribonuclease activity, producing 5'-phosphomonoesters; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:InterPro.
GO:0006396; P:RNA processing; IEA:InterPro.
9A8WQQ5    240   EXOS4_CAEBR Putative exosome complex componen...2333e-30     118     30     54GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0000178; C:exosome (RNase complex); IEA:UniProtKB-KW.::GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
10C5A2B9    249   ECX1_THEGJ Probable exosome complex exonuclea...2403e-29     115     33     52GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0000178; C:exosome (RNase complex); IEA:UniProtKB-KW.
GO:0016896; F:exoribonuclease activity, producing 5'-phosphomonoesters; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:InterPro.
GO:0006396; P:RNA processing; IEA:InterPro.
11Q5JIR6    249   ECX1_PYRKO Probable exosome complex exonuclea...2443e-29     115     32     52GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0000178; C:exosome (RNase complex); IEA:UniProtKB-KW.
GO:0016896; F:exoribonuclease activity, producing 5'-phosphomonoesters; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:InterPro.
GO:0006396; P:RNA processing; IEA:InterPro.
12O26779    240   ECX1_METTH Probable exosome complex exonuclea...2275e-29     114     31     52GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0000178; C:exosome (RNase complex); IEA:UniProtKB-KW.
GO:0016896; F:exoribonuclease activity, producing 5'-phosphomonoesters; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:InterPro.
GO:0006396; P:RNA processing; IEA:InterPro.
13Q97BZ5    248   ECX1_THEVO Probable exosome complex exonuclea...2291e-28     114     31     52GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0000178; C:exosome (RNase complex); IEA:UniProtKB-KW.
GO:0016896; F:exoribonuclease activity, producing 5'-phosphomonoesters; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:InterPro.
GO:0006396; P:RNA processing; IEA:InterPro.
14Q9V119    249   ECX1_PYRAB Probable exosome complex exonuclea...2431e-28     114     33     51GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0000178; C:exosome (RNase complex); IEA:UniProtKB-KW.
GO:0000175; F:3'-5'-exoribonuclease activity; IEA:HAMAP.::GO:0016896; F:exoribonuclease activity, producing 5'-phosphomonoesters; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:InterPro.
GO:0006401; P:RNA catabolic process; IEA:HAMAP.::GO:0006396; P:RNA processing; IEA:InterPro.
15Q8U0L9    250   ECX1_PYRFU Probable exosome complex exonuclea...2431e-28     113     33     51GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0000178; C:exosome (RNase complex); IEA:UniProtKB-KW.
GO:0016896; F:exoribonuclease activity, producing 5'-phosphomonoesters; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:InterPro.
GO:0006396; P:RNA processing; IEA:InterPro.
16B6YSI2    249   ECX1_THEON Probable exosome complex exonuclea...2322e-28     113     33     51GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0000178; C:exosome (RNase complex); IEA:UniProtKB-KW.
GO:0016896; F:exoribonuclease activity, producing 5'-phosphomonoesters; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:InterPro.
GO:0006396; P:RNA processing; IEA:InterPro.
17Q9HIP2    248   ECX1_THEAC Probable exosome complex exonuclea...2324e-28     112     30     51GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0000178; C:exosome (RNase complex); IEA:UniProtKB-KW.
GO:0016896; F:exoribonuclease activity, producing 5'-phosphomonoesters; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:InterPro.
GO:0006396; P:RNA processing; IEA:InterPro.
18O59223    249   ECX1_PYRHO Probable exosome complex exonuclea...2432e-27     110     33     51GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0000178; C:exosome (RNase complex); IEA:UniProtKB-KW.
GO:0016896; F:exoribonuclease activity, producing 5'-phosphomonoesters; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:InterPro.
GO:0006396; P:RNA processing; IEA:InterPro.
19Q8TYC1    239   ECX1_METKA Probable exosome complex exonuclea...1958e-27     108     35     53GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0000178; C:exosome (RNase complex); IEA:UniProtKB-KW.
GO:0016896; F:exoribonuclease activity, producing 5'-phosphomonoesters; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:InterPro.
GO:0006396; P:RNA processing; IEA:InterPro.
20Q8PTT8    493   ECX1_METMA Probable exosome complex exonuclea...2431e-26     110     31     51GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0000178; C:exosome (RNase complex); IEA:UniProtKB-KW.
GO:0016896; F:exoribonuclease activity, producing 5'-phosphomonoesters; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:InterPro.
GO:0006396; P:RNA processing; IEA:InterPro.
21Q975G8    243   ECX1_SULTO Probable exosome complex exonuclea...2292e-26     107     31     53GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0000178; C:exosome (RNase complex); IEA:UniProtKB-KW.
GO:0016896; F:exoribonuclease activity, producing 5'-phosphomonoesters; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:InterPro.
GO:0006396; P:RNA processing; IEA:InterPro.
22A2BKC0    255   ECX1_HYPBU Probable exosome complex exonuclea...2274e-26     107     31     52GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0000178; C:exosome (RNase complex); IEA:UniProtKB-KW.
GO:0016896; F:exoribonuclease activity, producing 5'-phosphomonoesters; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:InterPro.
GO:0006396; P:RNA processing; IEA:InterPro.
23B1Y978    246   ECX1_THENV Probable exosome complex exonuclea...2174e-25     104     34     52GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0000178; C:exosome (RNase complex); IEA:UniProtKB-KW.
GO:0016896; F:exoribonuclease activity, producing 5'-phosphomonoesters; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:InterPro.
GO:0006396; P:RNA processing; IEA:InterPro.
24Q4JB27    243   ECX1_SULAC Probable exosome complex exonuclea...1698e-25     103     39     56GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0000178; C:exosome (RNase complex); IEA:UniProtKB-KW.
GO:0016896; F:exoribonuclease activity, producing 5'-phosphomonoesters; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:InterPro.
GO:0006396; P:RNA processing; IEA:InterPro.
25A0RXU1    243   ECX1_CENSY Probable exosome complex exonuclea...2234e-24     101     31     55GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0000178; C:exosome (RNase complex); IEA:UniProtKB-KW.
GO:0016896; F:exoribonuclease activity, producing 5'-phosphomonoesters; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:InterPro.
GO:0006396; P:RNA processing; IEA:InterPro.
26Q9UXC2    248   ECX1_SULSO Probable exosome complex exonuclea...2278e-24     100     31     51GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0000178; C:exosome (RNase complex); IEA:UniProtKB-KW.
GO:0016896; F:exoribonuclease activity, producing 5'-phosphomonoesters; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:InterPro.
GO:0006396; P:RNA processing; IEA:InterPro.
27Q9YC03    246   ECX1_AERPE Probable exosome complex exonuclea...2292e-23     99.4     30     49GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0000178; C:exosome (RNase complex); IEA:UniProtKB-KW.
GO:0016896; F:exoribonuclease activity, producing 5'-phosphomonoesters; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:InterPro.
GO:0006396; P:RNA processing; IEA:InterPro.
28Q6P0I8    271   EXOS6_DANRE Exosome complex component MTR3 OS...2141e-22     97.8     28     48GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0000178; C:exosome (RNase complex); ISS:UniProtKB.::GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
29A1RST0    246   ECX1_PYRIL Probable exosome complex exonuclea...2171e-22     97.4     32     51GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0000178; C:exosome (RNase complex); IEA:UniProtKB-KW.
GO:0016896; F:exoribonuclease activity, producing 5'-phosphomonoesters; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:InterPro.
GO:0006396; P:RNA processing; IEA:InterPro.
30A3MUP1    246   ECX1_PYRCJ Probable exosome complex exonuclea...2265e-22     95.5     33     52GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0000178; C:exosome (RNase complex); IEA:UniProtKB-KW.
GO:0016896; F:exoribonuclease activity, producing 5'-phosphomonoesters; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:InterPro.
GO:0006396; P:RNA processing; IEA:InterPro.
31Q8ZVM9    246   ECX1_PYRAE Probable exosome complex exonuclea...2267e-19     86.7     31     51GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0000178; C:exosome (RNase complex); IEA:UniProtKB-KW.
GO:0016896; F:exoribonuclease activity, producing 5'-phosphomonoesters; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:InterPro.
GO:0006396; P:RNA processing; IEA:InterPro.
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