UniProt_SwissProt BLAST: Single locus

Species:

Saccharomyces cerevisiae S288C

Locus:

YGR193C

Length:

410

Number of sequences:

5887

Description:

YGR193C PDX1 SGDID:S000003425, Chr VII from 885741-884509, Genome Release 64-1-1, reverse complement, Verified ORF, "Dihydrolipoamide dehydrogenase (E3)-binding protein (E3BP) of the mitochondrial pyruvate dehydrogenase (PDH) complex, plays a structural role in the complex by binding and positioning E3 to the dihydrolipoamide acetyltransferase (E2) core"

rec.	Subject	Hit Length	Description	Align.Len	E value	Bit score	% ident.	% pos.	GO associations
61	P11181	482	ODB2_BOVIN Lipoamide acyltransferase componen...	162	0.0001	47.8	29	45
									GO:0048037; F:cofactor binding; IEA:InterPro.::GO:0043754; F:dihydrolipoyllysine-residue (2-methylpropanoyl)transferase activity; IEA:EC.
									GO:0046949; P:fatty-acyl-CoA biosynthetic process; IEA:InterPro.
62	P21883	442	ODP2_BACSU Dihydrolipoyllysine-residue acetyl...	198	0.0002	47	26	46
									GO:0004742; F:dihydrolipoyllysine-residue acetyltransferase activity; IEA:EC.
									GO:0006096; P:glycolysis; IEA:UniProtKB-KW.
63	Q8K9N2	393	ODO2_BUCAP Dihydrolipoyllysine-residue succin...	59	0.0007	45.1	37	63	GO:0045252; C:oxoglutarate dehydrogenase complex; IEA:InterPro.
									GO:0004149; F:dihydrolipoyllysine-residue succinyltransferase activity; IEA:EC.
									GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW.
64	P20708	399	ODO2_AZOVI Dihydrolipoyllysine-residue succin...	57	0.001	44.7	37	63	GO:0045252; C:oxoglutarate dehydrogenase complex; IEA:InterPro.
									GO:0004149; F:dihydrolipoyllysine-residue succinyltransferase activity; IEA:EC.
									GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW.
65	P11961	428	ODP2_GEOSE Dihydrolipoyllysine-residue acetyl...	178	0.001	44.3	25	43
									GO:0004742; F:dihydrolipoyllysine-residue acetyltransferase activity; IEA:EC.
									GO:0006096; P:glycolysis; IEA:UniProtKB-KW.
66	Q9I3D2	409	ODO2_PSEAE Dihydrolipoyllysine-residue succin...	57	0.002	43.5	39	61	GO:0045252; C:oxoglutarate dehydrogenase complex; IEA:InterPro.
									GO:0004149; F:dihydrolipoyllysine-residue succinyltransferase activity; IEA:EC.
									GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW.
67	Q8GCY1	411	ODO2_BARVB Dihydrolipoyllysine-residue succin...	178	0.004	42.7	28	46	GO:0045252; C:oxoglutarate dehydrogenase complex; IEA:InterPro.
									GO:0004149; F:dihydrolipoyllysine-residue succinyltransferase activity; IEA:EC.
									GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW.
68	P52993	416	ODO2_CUPNH Dihydrolipoyllysine-residue succin...	65	0.004	42.7	31	65	GO:0045252; C:oxoglutarate dehydrogenase complex; IEA:InterPro.
									GO:0004149; F:dihydrolipoyllysine-residue succinyltransferase activity; IEA:EC.
									GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW.
69	Q6ABX9	452	ODP2_LEIXX Dihydrolipoyllysine-residue acetyl...	70	0.005	42.7	34	60
									GO:0004742; F:dihydrolipoyllysine-residue acetyltransferase activity; IEA:EC.
									GO:0006096; P:glycolysis; IEA:UniProtKB-KW.
70	Q8H107	464	ODO2B_ARATH Dihydrolipoyllysine-residue succi...	145	0.005	42.7	28	50	GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.::GO:0045252; C:oxoglutarate dehydrogenase complex; IEA:InterPro.
									GO:0004149; F:dihydrolipoyllysine-residue succinyltransferase activity; IEA:EC.
									GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW.
71	P37942	424	ODB2_BACSU Lipoamide acyltransferase componen...	177	0.005	42.7	25	44
									GO:0043754; F:dihydrolipoyllysine-residue (2-methylpropanoyl)transferase activity; IEA:EC.
									GO:0006096; P:glycolysis; IEA:UniProtKB-KW.
72	P57389	420	ODO2_BUCAI Dihydrolipoyllysine-residue succin...	58	0.006	42.4	33	57	GO:0045252; C:oxoglutarate dehydrogenase complex; IEA:InterPro.
									GO:0004149; F:dihydrolipoyllysine-residue succinyltransferase activity; IEA:EC.
									GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW.
73	Q4L6C3	423	ODO2_STAHJ Dihydrolipoyllysine-residue succin...	107	0.007	42	30	54	GO:0045252; C:oxoglutarate dehydrogenase complex; IEA:InterPro.
									GO:0004149; F:dihydrolipoyllysine-residue succinyltransferase activity; IEA:EC.
									GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW.
74	P35489	544	ODP2_ACHLA Dihydrolipoyllysine-residue acetyl...	75	0.089	38.5	28	53
									GO:0004742; F:dihydrolipoyllysine-residue acetyltransferase activity; IEA:EC.
									GO:0006096; P:glycolysis; IEA:UniProtKB-KW.
75	Q89AJ6	410	ODO2_BUCBP Dihydrolipoyllysine-residue succin...	221	0.01	41.6	23	43	GO:0045252; C:oxoglutarate dehydrogenase complex; IEA:InterPro.
									GO:0004149; F:dihydrolipoyllysine-residue succinyltransferase activity; IEA:EC.
									GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW.
76	Q90512	409	ODO2_TAKRU Dihydrolipoyllysine-residue succin...	89	0.019	40.8	31	54	GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.::GO:0045252; C:oxoglutarate dehydrogenase complex; IEA:InterPro.
									GO:0004149; F:dihydrolipoyllysine-residue succinyltransferase activity; IEA:EC.
									GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW.
77	P36957	453	ODO2_HUMAN Dihydrolipoyllysine-residue succin...	76	0.03	40	33	59	GO:0005759; C:mitochondrial matrix; TAS:Reactome.::GO:0005634; C:nucleus; IDA:HPA.
									GO:0004149; F:dihydrolipoyllysine-residue succinyltransferase activity; IEA:EC.
									GO:0006554; P:lysine catabolic process; TAS:Reactome.::GO:0006099; P:tricarboxylic acid cycle; TAS:Reactome.
78	Q01205	454	ODO2_RAT Dihydrolipoyllysine-residue succinyl...	73	0.03	40	32	58	GO:0005792; C:microsome; IDA:RGD.::GO:0005739; C:mitochondrion; IDA:RGD.::GO:0045252; C:oxoglutarate dehydrogenase complex; IDA:RGD.::GO:0005886; C:plasma membrane; IDA:RGD.
									GO:0051087; F:chaperone binding; IPI:RGD.::GO:0004149; F:dihydrolipoyllysine-residue succinyltransferase activity; IDA:RGD.::GO:0031072; F:heat shock protein binding; IPI:RGD.
									GO:0006103; P:2-oxoglutarate metabolic process; IDA:RGD.::GO:0006734; P:NADH metabolic process; IDA:RGD.::GO:0006099; P:tricarboxylic acid cycle; IC:RGD.
79	P11179	455	ODO2_BOVIN Dihydrolipoyllysine-residue succin...	73	0.031	40	32	58	GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.::GO:0045252; C:oxoglutarate dehydrogenase complex; IEA:InterPro.
									GO:0004149; F:dihydrolipoyllysine-residue succinyltransferase activity; IEA:EC.
									GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW.
80	Q9D2G2	454	ODO2_MOUSE Dihydrolipoyllysine-residue succin...	73	0.031	40	32	58	GO:0005739; C:mitochondrion; IDA:MGI.
									GO:0004149; F:dihydrolipoyllysine-residue succinyltransferase activity; IEA:EC.
									GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW.
81	Q9N0F1	455	ODO2_PIG Dihydrolipoyllysine-residue succinyl...	73	0.033	40	32	58	GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.::GO:0045252; C:oxoglutarate dehydrogenase complex; IEA:InterPro.
									GO:0004149; F:dihydrolipoyllysine-residue succinyltransferase activity; IEA:EC.
									GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW.
82	Q59695	370	ACOC_PSEPU Dihydrolipoyllysine-residue acetyl...	49	0.089	38.5	37	59
									GO:0004742; F:dihydrolipoyllysine-residue acetyltransferase activity; IEA:EC.
									GO:0045150; P:acetoin catabolic process; IEA:UniProtKB-KW.
83	Q86AD5	413	Y1564_DICDI Pyruvate dehydrogenase complex su...	41	0.092	38.5	49	61	GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.::GO:0045254; C:pyruvate dehydrogenase complex; ISS:dictyBase.
									GO:0016746; F:transferase activity, transferring acyl groups; IEA:InterPro.
									GO:0006086; P:acetyl-CoA biosynthetic process from pyruvate; ISS:dictyBase.::GO:0006096; P:glycolysis; IEA:UniProtKB-KW.
84	P09062	423	ODB2_PSEPU Lipoamide acyltransferase componen...	264	0.11	38.1	22	42
									GO:0043754; F:dihydrolipoyllysine-residue (2-methylpropanoyl)transferase activity; IEA:EC.
									GO:0006096; P:glycolysis; IEA:UniProtKB-KW.
85	P65633	553	ODO2_MYCTU Dihydrolipoyllysine-residue succin...	72	1.1	35	29	51	GO:0005829; C:cytosol; IDA:MTBBASE.::GO:0005886; C:plasma membrane; IDA:MTBBASE.::GO:0045254; C:pyruvate dehydrogenase complex; IDA:MTBBASE.
									GO:0016209; F:antioxidant activity; IEA:UniProtKB-KW.::GO:0004148; F:dihydrolipoyl dehydrogenase activity; IDA:MTBBASE.::GO:0004149; F:dihydrolipoyllysine-residue succinyltransferase activity; IEA:EC.::GO:0031405; F:lipoic acid binding; IDA:MTBBASE.::GO:0005515; F:protein binding; IPI:MTBBASE.
									GO:0045454; P:cell redox homeostasis; IDA:MTBBASE.::GO:0040007; P:growth; IMP:MTBBASE.::GO:0009405; P:pathogenesis; IDA:MTBBASE.::GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW.
86	P65634	553	ODO2_MYCBO Dihydrolipoyllysine-residue succin...	72	1.1	35	29	51
									GO:0004149; F:dihydrolipoyllysine-residue succinyltransferase activity; IEA:EC.
									GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW.
87	Q9FLQ4	464	ODO2A_ARATH Dihydrolipoyllysine-residue succi...	114	0.3	37	25	46	GO:0022626; C:cytosolic ribosome; IDA:TAIR.::GO:0005739; C:mitochondrion; IDA:TAIR.::GO:0045252; C:oxoglutarate dehydrogenase complex; IEA:InterPro.
									GO:0004149; F:dihydrolipoyllysine-residue succinyltransferase activity; IEA:EC.::GO:0008270; F:zinc ion binding; IDA:TAIR.
									GO:0006979; P:response to oxidative stress; IDA:TAIR.::GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW.
88	Q89AQ9	410	ODP2_BUCBP Dihydrolipoyllysine-residue acetyl...	159	1	35	25	43
									GO:0004742; F:dihydrolipoyllysine-residue acetyltransferase activity; IEA:EC.
									GO:0006096; P:glycolysis; IEA:UniProtKB-KW.
89	O94681	452	ODO2_SCHPO Probable dihydrolipoyllysine-resid...	106	1.6	34.7	29	42	GO:0042645; C:mitochondrial nucleoid; ISS:PomBase.::GO:0009353; C:mitochondrial oxoglutarate dehydrogenase complex; IC:PomBase.
									GO:0004149; F:dihydrolipoyllysine-residue succinyltransferase activity; ISS:PomBase.::GO:0016491; F:oxidoreductase activity; NAS:PomBase.
									GO:0006103; P:2-oxoglutarate metabolic process; ISS:PomBase.::GO:0006099; P:tricarboxylic acid cycle; ISS:PomBase.
90	P27747	374	ACOC_CUPNH Dihydrolipoyllysine-residue acetyl...	58	2.1	34.3	36	52
									GO:0004742; F:dihydrolipoyllysine-residue acetyltransferase activity; IEA:EC.
									GO:0045150; P:acetoin catabolic process; IEA:UniProtKB-KW.
91	Q58628	567	PYCB_METJA Pyruvate carboxylase subunit B OS=...	62	3	33.9	35	56
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0008948; F:oxaloacetate decarboxylase activity; IEA:InterPro.::GO:0004736; F:pyruvate carboxylase activity; IEA:EC.
									GO:0006094; P:gluconeogenesis; IEA:UniProtKB-KW.::GO:0006814; P:sodium ion transport; IEA:InterPro.

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