Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YGR188C
Length:
1021
Number of sequences:
5887
Description:
YGR188C BUB1 SGDID:S000003420, Chr VII from 875109-872044, Genome Release 64-1-1, reverse complement, Verified ORF, "Protein kinase involved in the cell cycle checkpoint into anaphase; forms complex with Mad1p and Bub3p crucial to preventing cell cycle progression into anaphase in the presence of spindle damage; CDC28-mediated phosphorylation at Bub1p-T566 is important for its degradation in anaphase and adaptation of the checkpoint to prolonged mitotic arrest, but not to its kinase activity or chromosome segregation function; associates with centromere DNA via Skp1p"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
361B6A7Q3    468   CDK14_RABIT Cyclin-dependent kinase 14 OS=Ory...1400.044     41.2     30     51GO:0000308; C:cytoplasmic cyclin-dependent protein kinase holoenzyme complex; ISS:UniProtKB.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; ISS:UniProtKB.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0000086; P:G2/M transition of mitotic cell cycle; ISS:UniProtKB.::GO:0060828; P:regulation of canonical Wnt receptor signaling pathway; ISS:UniProtKB.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
362Q8WXR4    1341   MYO3B_HUMAN Myosin-IIIb OS=Homo sapiens (Huma...2190.044     41.6     22     40GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0016459; C:myosin complex; IEA:UniProtKB-KW.
GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003774; F:motor activity; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0050896; P:response to stimulus; IEA:UniProtKB-KW.::GO:0007601; P:visual perception; IEA:UniProtKB-KW.
363O74426    338   PPK33_SCHPO Serine/threonine-protein kinase p...1420.045     40.8     29     45
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; TAS:PomBase.
GO:0007165; P:signal transduction; NAS:PomBase.
364Q8BN21    503   VRK2_MOUSE Serine/threonine-protein kinase VR...1890.045     41.2     20     41GO:0005789; C:endoplasmic reticulum membrane; ISS:UniProtKB.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005624; C:membrane fraction; IDA:MGI.::GO:0031966; C:mitochondrial membrane; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IDA:MGI.
GO:0046777; P:protein autophosphorylation; IDA:MGI.::GO:2000659; P:regulation of interleukin-1-mediated signaling pathway; ISS:UniProtKB.::GO:0043408; P:regulation of MAPK cascade; ISS:UniProtKB.::GO:0006979; P:response to oxidative stress; ISS:UniProtKB.
365Q6FP74    773   CBK1_CANGA Serine/threonine-protein kinase CB...1370.046     41.6     24     45
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
366Q2QY53    438   CIPKW_ORYSJ CBL-interacting protein kinase 32...1370.046     41.2     24     48
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0007165; P:signal transduction; IEA:InterPro.
367Q54DC8    1224   Y2350_DICDI Probable serine/threonine-protein...1440.047     41.6     27     44
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
368A2YBX5    589   G11A_ORYSI Protein kinase G11A OS=Oryza sativ...1370.047     41.2     28     47
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
369Q12701    592   KSG1_SCHPO Serine/threonine-protein kinase ks...1350.048     41.2     29     43GO:0005737; C:cytoplasm; IDA:PomBase.
GO:0004676; F:3-phosphoinositide-dependent protein kinase activity; ISS:PomBase.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:PomBase.
GO:0030437; P:ascospore formation; IMP:PomBase.::GO:0031505; P:fungal-type cell wall organization; IMP:PomBase.::GO:0031137; P:regulation of conjugation with cellular fusion; IMP:PomBase.::GO:0007165; P:signal transduction; IC:PomBase.
370O61122    478   SVKA_DICDI Serine/threonine-protein kinase sv...660.048     41.2     33     52GO:0030479; C:actin cortical patch; IEA:UniProtKB-SubCell.::GO:0005813; C:centrosome; IDA:dictyBase.::GO:0032154; C:cleavage furrow; IDA:dictyBase.
GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IMP:UniProtKB.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0006972; P:hyperosmotic response; IEP:dictyBase.::GO:0051781; P:positive regulation of cell division; IMP:UniProtKB.::GO:0046777; P:protein autophosphorylation; IDA:dictyBase.::GO:0032956; P:regulation of actin cytoskeleton organization; IMP:UniProtKB.::GO:0010590; P:regulation of cytokinetic cell separation; IMP:dictyBase.::GO:0031156; P:regulation of sorocarp development; IMP:dictyBase.::GO:0007165; P:signal transduction; ISS:dictyBase.
371Q6VZ17    626   HUNKB_XENLA Hormonally up-regulated neu tumor...1580.048     41.2     22     41
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
372P53739    893   FPK1_YEAST Flippase kinase 1 OS=Saccharomyces...2350.05     41.2     22     39GO:0005737; C:cytoplasm; IDA:SGD.::GO:0005886; C:plasma membrane; IDA:SGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IMP:SGD.
GO:0006869; P:lipid transport; IEA:UniProtKB-KW.::GO:0046777; P:protein autophosphorylation; IDA:SGD.::GO:0019236; P:response to pheromone; IMP:SGD.
373P25389    1037   KCC4_YEAST Probable serine/threonine-protein ...2370.05     41.2     22     42GO:0032174; C:cellular bud neck septin collar; IDA:SGD.::GO:0000131; C:incipient cellular bud site; IDA:SGD.::GO:0005886; C:plasma membrane; IDA:UniProtKB.::GO:0005940; C:septin ring; IDA:SGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0070300; F:phosphatidic acid binding; IDA:UniProtKB.::GO:0005546; F:phosphatidylinositol-4,5-bisphosphate binding; IDA:UniProtKB.::GO:0001786; F:phosphatidylserine binding; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0007117; P:budding cell bud growth; IMP:SGD.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0008360; P:regulation of cell shape; IEA:UniProtKB-KW.::GO:0000135; P:septin checkpoint; IGI:SGD.::GO:0000921; P:septin ring assembly; IMP:SGD.
374Q8VZJ9    411   Y4330_ARATH Probable leucine-rich repeat rece...1380.05     40.8     25     46GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0009555; P:pollen development; IMP:TAIR.
375Q39238    688   TSL_ARATH Serine/threonine-protein kinase TOU...2640.052     41.2     23     40GO:0009507; C:chloroplast; IDA:TAIR.::GO:0005634; C:nucleus; IDA:TAIR.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0042802; F:identical protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; IDA:TAIR.
376Q2QMI0    454   CIPK4_ORYSJ CBL-interacting protein kinase 4 ...1430.052     40.8     29     43
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0007165; P:signal transduction; IEA:InterPro.
377Q60855    656   RIPK1_MOUSE Receptor-interacting serine/threo...1410.055     41.2     26     47
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW.::GO:2001243; P:negative regulation of intrinsic apoptotic signaling pathway; IMP:UniProtKB.::GO:0042327; P:positive regulation of phosphorylation; IMP:UniProtKB.::GO:0007165; P:signal transduction; IEA:InterPro.
378P31034    718   CBK1_KLULA Serine/threonine-protein kinase CB...1370.056     41.2     25     44
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
379Q93VD3    482   CIPKN_ARATH CBL-interacting serine/threonine-...1370.058     40.8     26     47GO:0005829; C:cytosol; IDA:TAIR.::GO:0005634; C:nucleus; IDA:TAIR.::GO:0005886; C:plasma membrane; IPI:TAIR.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005267; F:potassium channel activity; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; IDA:TAIR.
GO:0010107; P:potassium ion import; IMP:TAIR.::GO:0007584; P:response to nutrient; IMP:TAIR.::GO:0009414; P:response to water deprivation; IMP:TAIR.::GO:0007165; P:signal transduction; IEA:InterPro.::GO:0010118; P:stomatal movement; IMP:TAIR.
380B5DE93    1239   CDK12_XENTR Cyclin-dependent kinase 12 OS=Xen...1550.058     41.2     27     46GO:0019908; C:nuclear cyclin-dependent protein kinase holoenzyme complex; ISS:UniProtKB.::GO:0016607; C:nuclear speck; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; ISS:UniProtKB.
GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0070816; P:phosphorylation of RNA polymerase II C-terminal domain; ISS:UniProtKB.::GO:0043405; P:regulation of MAP kinase activity; ISS:UniProtKB.::GO:0008380; P:RNA splicing; ISS:UniProtKB.
381Q64FQ2    525   PID2_ARATH Protein kinase PINOID 2 OS=Arabido...1770.058     40.8     25     39
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0009734; P:auxin mediated signaling pathway; IEA:UniProtKB-KW.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
382Q23551    7158   UNC22_CAEEL Twitchin OS=Caenorhabditis elegan...2360.06     41.2     25     39GO:0031672; C:A band; IDA:WormBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0040011; P:locomotion; IMP:WormBase.::GO:0040015; P:negative regulation of multicellular organism growth; IMP:WormBase.::GO:0040027; P:negative regulation of vulval development; IMP:WormBase.::GO:0040018; P:positive regulation of multicellular organism growth; IMP:WormBase.::GO:0000003; P:reproduction; IMP:WormBase.
383Q2L6W9    476   SAX1_CAEEL Serine/threonine-protein kinase sa...1360.06     40.8     24     46GO:0030424; C:axon; IDA:WormBase.::GO:0005737; C:cytoplasm; IDA:WormBase.::GO:0030425; C:dendrite; IDA:WormBase.::GO:0005634; C:nucleus; IDA:WormBase.
GO:0005524; F:ATP binding; ISS:WormBase.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; ISS:WormBase.
GO:0030031; P:cell projection assembly; IMP:WormBase.::GO:0007163; P:establishment or maintenance of cell polarity; IMP:WormBase.::GO:0030308; P:negative regulation of cell growth; IMP:WormBase.::GO:0031175; P:neuron projection development; IMP:WormBase.::GO:0008360; P:regulation of cell shape; IMP:WormBase.
384Q55FS2    1105   STK4L_DICDI Serine/threonine-protein kinase 4...1500.061     41.2     23     46GO:0005737; C:cytoplasm; ISS:dictyBase.::GO:0005634; C:nucleus; ISS:dictyBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; ISS:dictyBase.
GO:0006915; P:apoptotic process; ISS:dictyBase.::GO:0008283; P:cell proliferation; ISS:dictyBase.::GO:0007165; P:signal transduction; ISS:dictyBase.
385P25323    295   MYLKA_DICDI Myosin light chain kinase A OS=Di...1410.062     40.4     27     49GO:0005737; C:cytoplasm; IDA:dictyBase.
GO:0030898; F:actin-dependent ATPase activity; IDA:dictyBase.::GO:0005524; F:ATP binding; IC:dictyBase.::GO:0004687; F:myosin light chain kinase activity; IDA:dictyBase.
GO:0019933; P:cAMP-mediated signaling; IDA:dictyBase.::GO:0019934; P:cGMP-mediated signaling; IDA:dictyBase.::GO:0000910; P:cytokinesis; IMP:dictyBase.::GO:0046777; P:protein autophosphorylation; IDA:dictyBase.::GO:0050920; P:regulation of chemotaxis; IMP:dictyBase.
386Q8G4G1    757   PKNA2_BIFLO Probable serine/threonine-protein...1450.063     40.8     27     43
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008658; F:penicillin binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
387Q5KQF5    451   CIPKM_ORYSJ CBL-interacting protein kinase 22...660.063     40.8     32     52
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0007165; P:signal transduction; IEA:InterPro.
388P38938    1338   CEK1_SCHPO Serine/threonine-protein kinase ce...1440.064     41.2     26     49GO:0005829; C:cytosol; IDA:PomBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; TAS:PomBase.::GO:0004871; F:signal transducer activity; IEA:InterPro.
GO:0051519; P:activation of bipolar cell growth; IMP:PomBase.::GO:0007346; P:regulation of mitotic cell cycle; IGI:PomBase.
389P25390    1331   SSK22_YEAST Serine/threonine-protein kinase S...1380.064     41.2     22     49
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004709; F:MAP kinase kinase kinase activity; ISS:SGD.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0000161; P:MAPK cascade involved in osmosensory signaling pathway; IMP:SGD.
390Q9ZV15    583   CDPKK_ARATH Calcium-dependent protein kinase ...2350.064     40.8     23     39GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
391Q754N7    719   CBK1_ASHGO Serine/threonine-protein kinase CB...690.064     40.8     32     51
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
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