UniProt_SwissProt BLAST: Single locus

Species:

Saccharomyces cerevisiae S288C

Locus:

YGR175C

Length:

496

Number of sequences:

5887

Description:

YGR175C ERG1 SGDID:S000003407, Chr VII from 848423-846933, Genome Release 64-1-1, reverse complement, Verified ORF, "Squalene epoxidase, catalyzes the epoxidation of squalene to 2,3-oxidosqualene; plays an essential role in the ergosterol-biosynthesis pathway and is the specific target of the antifungal drug terbinafine"

rec.	Subject	Hit Length	Description	Align.Len	E value	Bit score	% ident.	% pos.	GO associations
91	Q9VMQ5	477	COQ6_DROME Putative ubiquinone biosynthesis m...	54	1.4	35	35	52
									GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0016709; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen; IEA:InterPro.
									GO:0006744; P:ubiquinone biosynthetic process; IEA:UniProtKB-KW.
92	Q9D826	390	SOX_MOUSE Peroxisomal sarcosine oxidase OS=Mu...	37	1.4	35	49	65	GO:0005777; C:peroxisome; IDA:HGNC.
									GO:0050031; F:L-pipecolate oxidase activity; ISS:UniProtKB.::GO:0008115; F:sarcosine oxidase activity; ISS:UniProtKB.
									GO:0033514; P:L-lysine catabolic process to acetyl-CoA via L-pipecolate; ISS:UniProtKB.::GO:0046653; P:tetrahydrofolate metabolic process; IEA:InterPro.
93	Q8R1S0	469	COQ6_MOUSE Ubiquinone biosynthesis monooxygen...	85	1.6	35	24	51
									GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0016709; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen; IEA:InterPro.
									GO:0006744; P:ubiquinone biosynthetic process; IEA:UniProtKB-KW.
94	P09820	435	FIXC_RHIME Protein fixC OS=meliloti). GN=fixC...	31	1.8	34.7	52	71
									GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
									GO:0009399; P:nitrogen fixation; IEA:UniProtKB-KW.
95	Q8BXR9	959	OSBL6_MOUSE Oxysterol-binding protein-related...	123	1.9	35	26	43
									GO:0005543; F:phospholipid binding; IEA:InterPro.
									GO:0006869; P:lipid transport; IEA:UniProtKB-KW.
96	Q6L0M1	397	GGR_PICTO Digeranylgeranylglycerophospholipid...	33	2	34.7	48	64
									GO:0045550; F:geranylgeranyl reductase activity; IEA:InterPro.::GO:0016628; F:oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor; IEA:InterPro.
									GO:0046467; P:membrane lipid biosynthetic process; IEA:InterPro.::GO:0008654; P:phospholipid biosynthetic process; IEA:UniProtKB-KW.
97	Q9M9Y8	595	CRTSO_ARATH Prolycopene isomerase, chloroplas...	31	2	34.7	55	74	GO:0031969; C:chloroplast membrane; IEA:UniProtKB-SubCell.
									GO:0046608; F:carotenoid isomerase activity; IGI:TAIR.
									GO:0016117; P:carotenoid biosynthetic process; IGI:TAIR.::GO:0009662; P:etioplast organization; IMP:TAIR.
98	Q31JE7	674	MNMC_THICR tRNA 5-methylaminomethyl-2-thiouri...	41	2	34.7	44	63	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0016645; F:oxidoreductase activity, acting on the CH-NH group of donors; IEA:InterPro.::GO:0004808; F:tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity; IEA:EC.
99	A1JI37	466	STHA_YERE8 Soluble pyridine nucleotide transh...	31	2.1	34.7	48	71	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0003957; F:NAD(P)+ transhydrogenase (B-specific) activity; IEA:EC.
									GO:0045454; P:cell redox homeostasis; IEA:InterPro.
100	B1JQ50	466	STHA_YERPY Soluble pyridine nucleotide transh...	31	2.1	34.7	48	71	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0003957; F:NAD(P)+ transhydrogenase (B-specific) activity; IEA:EC.
									GO:0045454; P:cell redox homeostasis; IEA:InterPro.
101	Q66G61	466	STHA_YERPS Soluble pyridine nucleotide transh...	31	2.1	34.7	48	71	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0003957; F:NAD(P)+ transhydrogenase (B-specific) activity; IEA:EC.
									GO:0045454; P:cell redox homeostasis; IEA:InterPro.
102	A4TRG4	466	STHA_YERPP Soluble pyridine nucleotide transh...	31	2.1	34.7	48	71	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0003957; F:NAD(P)+ transhydrogenase (B-specific) activity; IEA:EC.
									GO:0045454; P:cell redox homeostasis; IEA:InterPro.
103	Q1CNP4	466	STHA_YERPN Soluble pyridine nucleotide transh...	31	2.1	34.7	48	71	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0003957; F:NAD(P)+ transhydrogenase (B-specific) activity; IEA:EC.
									GO:0045454; P:cell redox homeostasis; IEA:InterPro.
104	A9R6N5	466	STHA_YERPG Soluble pyridine nucleotide transh...	31	2.1	34.7	48	71	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0003957; F:NAD(P)+ transhydrogenase (B-specific) activity; IEA:EC.
									GO:0045454; P:cell redox homeostasis; IEA:InterPro.
105	Q8ZA97	466	STHA_YERPE Soluble pyridine nucleotide transh...	31	2.1	34.7	48	71	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0003957; F:NAD(P)+ transhydrogenase (B-specific) activity; IEA:EC.
									GO:0045454; P:cell redox homeostasis; IEA:InterPro.
106	B2JZF3	466	STHA_YERPB Soluble pyridine nucleotide transh...	31	2.1	34.7	48	71	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0003957; F:NAD(P)+ transhydrogenase (B-specific) activity; IEA:EC.
									GO:0045454; P:cell redox homeostasis; IEA:InterPro.
107	Q1CBU5	466	STHA_YERPA Soluble pyridine nucleotide transh...	31	2.1	34.7	48	71	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0003957; F:NAD(P)+ transhydrogenase (B-specific) activity; IEA:EC.
									GO:0045454; P:cell redox homeostasis; IEA:InterPro.
108	A7FD10	466	STHA_YERP3 Soluble pyridine nucleotide transh...	31	2.1	34.7	48	71	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0003957; F:NAD(P)+ transhydrogenase (B-specific) activity; IEA:EC.
									GO:0045454; P:cell redox homeostasis; IEA:InterPro.
109	Q18006	384	SOX_CAEEL Putative sarcosine oxidase OS=Caeno...	31	2.2	34.3	42	65	GO:0005777; C:peroxisome; ISS:UniProtKB.
									GO:0050031; F:L-pipecolate oxidase activity; ISS:UniProtKB.::GO:0008115; F:sarcosine oxidase activity; ISS:UniProtKB.
									GO:0033514; P:L-lysine catabolic process to acetyl-CoA via L-pipecolate; ISS:UniProtKB.
110	Q5BLE8	607	RETST_DANRE Putative all-trans-retinol 13,14-...	30	2.2	34.7	50	80	GO:0005789; C:endoplasmic reticulum membrane; IBA:RefGenome.
									GO:0051786; F:all-trans-retinol 13,14-reductase activity; IDA:ZFIN.
									GO:0042572; P:retinol metabolic process; IBA:RefGenome.
111	A8GL77	465	STHA_SERP5 Soluble pyridine nucleotide transh...	31	2.2	34.7	48	71	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0003957; F:NAD(P)+ transhydrogenase (B-specific) activity; IEA:EC.
									GO:0045454; P:cell redox homeostasis; IEA:InterPro.
112	P37747	367	GLF_ECOLI UDP-galactopyranose mutase OS=Esche...	31	2.3	34.3	42	68
									GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0008767; F:UDP-galactopyranose mutase activity; IDA:EcoCyc.
									GO:0009103; P:lipopolysaccharide biosynthetic process; IEA:UniProtKB-KW.
113	Q2T2K1	654	MNMC_BURTA tRNA 5-methylaminomethyl-2-thiouri...	87	2.4	34.7	32	43	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016645; F:oxidoreductase activity, acting on the CH-NH group of donors; IEA:InterPro.::GO:0004808; F:tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity; IEA:EC.
114	Q48A14	466	STHA_COLP3 Soluble pyridine nucleotide transh...	36	2.7	34.3	44	61	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0003957; F:NAD(P)+ transhydrogenase (B-specific) activity; IEA:EC.
									GO:0045454; P:cell redox homeostasis; IEA:InterPro.
115	Q53208	435	FIXC_RHISN Protein fixC OS=Rhizobium sp. (str...	31	2.9	34.3	52	71
									GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
									GO:0009399; P:nitrogen fixation; IEA:UniProtKB-KW.::GO:0008033; P:tRNA processing; IEA:InterPro.
116	Q9F131	394	3HBH1_PSEAC 3-hydroxybenzoate 6-hydroxylase 1...	54	3.2	33.9	33	57
									GO:0018669; F:3-hydroxybenzoate 6-monooxygenase activity; IEA:EC.
									GO:0019439; P:aromatic compound catabolic process; IEA:UniProtKB-KW.
117	A0PW28	473	HEM1_MYCUA Glutamyl-tRNA reductase OS=Mycobac...	54	3.2	33.9	37	56
									GO:0008883; F:glutamyl-tRNA reductase activity; IEA:EC.::GO:0050661; F:NADP binding; IEA:InterPro.
									GO:0006779; P:porphyrin-containing compound biosynthetic process; IEA:UniProtKB-KW.
118	Q54PQ8	1135	XPO5_DICDI Exportin-5 OS=Dictyostelium discoi...	123	3.8	33.9	24	49	GO:0005829; C:cytosol; ISS:dictyBase.::GO:0005635; C:nuclear envelope; ISS:dictyBase.
									GO:0008565; F:protein transporter activity; ISS:dictyBase.::GO:0000049; F:tRNA binding; ISS:dictyBase.
									GO:0006611; P:protein export from nucleus; ISS:dictyBase.
119	Q0V5K1	482	KMO_PHANO Kynurenine 3-monooxygenase OS=(Glum...	75	4.1	33.5	33	48	GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.
									GO:0004502; F:kynurenine 3-monooxygenase activity; IEA:EC.
									GO:0019363; P:pyridine nucleotide biosynthetic process; IEA:UniProtKB-KW.
120	Q54EN1	495	COQ6_DICDI Ubiquinone biosynthesis monooxygen...	79	4.1	33.5	29	54
									GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0016709; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen; IEA:InterPro.
									GO:0006744; P:ubiquinone biosynthetic process; IEA:UniProtKB-KW.
121	Q7NBE9	328	FENR_MYCGA Ferredoxin--NADP reductase OS=Myco...	66	4.3	33.5	38	48
									GO:0004324; F:ferredoxin-NADP+ reductase activity; IEA:EC.::GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0000166; F:nucleotide binding; IEA:InterPro.

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