Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
Home About FGC Use Cases Species List

UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YGR175C
Length:
496
Number of sequences:
5887
Description:
YGR175C ERG1 SGDID:S000003407, Chr VII from 848423-846933, Genome Release 64-1-1, reverse complement, Verified ORF, "Squalene epoxidase, catalyzes the epoxidation of squalene to 2,3-oxidosqualene; plays an essential role in the ergosterol-biosynthesis pathway and is the specific target of the antifungal drug terbinafine"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
1P32476    496   ERG1_YEAST Squalene monooxygenase OS=Saccharo...4960     1018     100     100GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005811; C:lipid particle; IDA:SGD.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell.
GO:0008144; F:drug binding; IMP:SGD.::GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0004506; F:squalene monooxygenase activity; IDA:SGD.
GO:0006696; P:ergosterol biosynthetic process; IMP:SGD.
2O13306    489   ERG1_CANGA Squalene monooxygenase OS=NRRL Y-6...4880     874     85     93GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell.
GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0004506; F:squalene monooxygenase activity; IEA:EC.
3Q75F69    497   ERG1_ASHGO Squalene monooxygenase OS=Y-1056) ...4870     676     65     79GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell.
GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0004506; F:squalene monooxygenase activity; IEA:EC.
4Q92206    496   ERG1_CANAL Squalene monooxygenase OS=Candida ...4966e-173     503     52     68GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IDA:CGD.
GO:0003857; F:3-hydroxyacyl-CoA dehydrogenase activity; IEA:InterPro.::GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0004506; F:squalene monooxygenase activity; IDA:CGD.
GO:0035690; P:cellular response to drug; IMP:CGD.::GO:0006696; P:ergosterol biosynthetic process; IMP:CGD.::GO:0006631; P:fatty acid metabolic process; IEA:InterPro.::GO:0030448; P:hyphal growth; IMP:CGD.::GO:0051668; P:localization within membrane; IMP:CGD.
5Q9C1W3    457   ERG1_SCHPO Probable squalene monooxygenase OS...4726e-105     328     38     55GO:0005789; C:endoplasmic reticulum membrane; ISS:PomBase.::GO:0000329; C:fungal-type vacuole membrane; IDA:PomBase.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell.
GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0004506; F:squalene monooxygenase activity; ISS:PomBase.
GO:0006696; P:ergosterol biosynthetic process; ISS:PomBase.
6P52019    572   ERG1_MOUSE Squalene monooxygenase OS=Mus musc...4801e-95     307     36     55GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell.
GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0004506; F:squalene monooxygenase activity; IEA:EC.
7P52020    573   ERG1_RAT Squalene monooxygenase OS=Rattus nor...4802e-94     304     36     55GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005792; C:microsome; IDA:RGD.
GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0004506; F:squalene monooxygenase activity; IDA:RGD.
GO:0006725; P:cellular aromatic compound metabolic process; IDA:RGD.::GO:0008203; P:cholesterol metabolic process; IMP:RGD.::GO:0010033; P:response to organic substance; IDA:RGD.
8Q14534    574   ERG1_HUMAN Squalene monooxygenase OS=Homo sap...4801e-93     302     37     55GO:0005789; C:endoplasmic reticulum membrane; TAS:Reactome.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005792; C:microsome; NAS:UniProtKB.
GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0004506; F:squalene monooxygenase activity; NAS:UniProtKB.
GO:0006695; P:cholesterol biosynthetic process; TAS:Reactome.
9O48651    539   ERG1_PANGI Squalene monooxygenase OS=Panax gi...4451e-78     261     38     51GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0004506; F:squalene monooxygenase activity; IEA:EC.
10O65726    518   ERG12_BRANA Squalene monooxygenase 1,2 OS=Bra...4865e-51     187     28     47GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0004506; F:squalene monooxygenase activity; IEA:EC.
11O65402    517   ERG12_ARATH Squalene monooxygenase 1,2 OS=Ara...4462e-50     185     29     48GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0004506; F:squalene monooxygenase activity; IEA:EC.
12O65727    506   ERG11_BRANA Squalene monooxygenase 1,1 OS=Bra...4322e-49     182     29     48GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0004506; F:squalene monooxygenase activity; IEA:EC.
13O65404    516   ERG11_ARATH Squalene monooxygenase 1,1 OS=Ara...4632e-49     182     28     48GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0004506; F:squalene monooxygenase activity; IEA:EC.
14O65403    516   ERG13_ARATH Squalene monooxygenase 2 OS=Arabi...4472e-47     176     27     47GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0004506; F:squalene monooxygenase activity; IEA:EC.
15C5A6E5    395   GGR_THEGJ Digeranylgeranylglycerophospholipid...380.003     43.5     45     71
GO:0045550; F:geranylgeranyl reductase activity; IEA:InterPro.::GO:0016628; F:oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor; IEA:InterPro.
GO:0046467; P:membrane lipid biosynthetic process; IEA:InterPro.::GO:0008654; P:phospholipid biosynthetic process; IEA:UniProtKB-KW.
16Q7Q6A7    486   KMO_ANOGA Kynurenine 3-monooxygenase OS=Anoph...4100.003     43.5     20     37GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005741; C:mitochondrial outer membrane; ISS:UniProtKB.
GO:0004502; F:kynurenine 3-monooxygenase activity; ISS:UniProtKB.
GO:0019674; P:NAD metabolic process; ISS:UniProtKB.::GO:0019363; P:pyridine nucleotide biosynthetic process; IEA:UniProtKB-KW.
17O01884    451   COQ6_CAEEL Probable ubiquinone biosynthesis m...3960.004     43.1     20     37
GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0016709; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen; IEA:InterPro.
GO:0008340; P:determination of adult lifespan; IMP:WormBase.::GO:0006744; P:ubiquinone biosynthetic process; IMP:WormBase.
18A0M4X2    447   KMO_GRAFK Kynurenine 3-monooxygenase OS=Grame...4180.005     43.1     21     34
GO:0004502; F:kynurenine 3-monooxygenase activity; IEA:EC.
GO:0019363; P:pyridine nucleotide biosynthetic process; IEA:UniProtKB-KW.
19Q5JE27    395   GGR_PYRKO Digeranylgeranylglycerophospholipid...380.007     42.4     42     71
GO:0045550; F:geranylgeranyl reductase activity; IEA:InterPro.::GO:0016628; F:oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor; IEA:InterPro.
GO:0046467; P:membrane lipid biosynthetic process; IEA:InterPro.::GO:0008654; P:phospholipid biosynthetic process; IEA:UniProtKB-KW.
20Q8S4R4    615   CRTSO_SOLLC Prolycopene isomerase, chloroplas...390.033     40.4     49     72GO:0031969; C:chloroplast membrane; IEA:UniProtKB-SubCell.
GO:0016853; F:isomerase activity; IEA:UniProtKB-KW.
GO:0016117; P:carotenoid biosynthetic process; IEA:UniProtKB-KW.
21Q2VEX9    615   CRTSO_DAUCA Prolycopene isomerase, chloroplas...410.049     40     49     66GO:0031969; C:chloroplast membrane; IEA:UniProtKB-SubCell.
GO:0016853; F:isomerase activity; IEA:UniProtKB-KW.
GO:0016117; P:carotenoid biosynthetic process; IEA:UniProtKB-KW.
22Q9U641    510   CMFB_DICDI Conditioned medium factor receptor...4540.073     39.3     23     39GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0016491; F:oxidoreductase activity; IEA:InterPro.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW.
23Q86PM2    476   KMO_AEDAE Kynurenine 3-monooxygenase OS=Aedes...2230.099     38.9     23     37GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005741; C:mitochondrial outer membrane; ISS:UniProtKB.
GO:0004502; F:kynurenine 3-monooxygenase activity; IDA:UniProtKB.
GO:0019674; P:NAD metabolic process; IDA:UniProtKB.::GO:0019363; P:pyridine nucleotide biosynthetic process; IEA:UniProtKB-KW.
24Q52QW3    587   CRTS1_ONCHC Prolycopene isomerase 1, chloropl...500.12     38.9     46     64GO:0031969; C:chloroplast membrane; IEA:UniProtKB-SubCell.
GO:0016853; F:isomerase activity; IEA:UniProtKB-KW.
GO:0016117; P:carotenoid biosynthetic process; IEA:UniProtKB-KW.
25Q52QW2    587   CRTS2_ONCHC Prolycopene isomerase 2, chloropl...500.12     38.5     46     64GO:0031969; C:chloroplast membrane; IEA:UniProtKB-SubCell.
GO:0016853; F:isomerase activity; IEA:UniProtKB-KW.
GO:0016117; P:carotenoid biosynthetic process; IEA:UniProtKB-KW.
26Q6CZB1    468   STHA_ERWCT Soluble pyridine nucleotide transh...380.13     38.5     42     66GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.::GO:0003957; F:NAD(P)+ transhydrogenase (B-specific) activity; IEA:EC.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.
27Q83SQ7    428   FIXC_SHIFL Protein fixC OS=Shigella flexneri....310.13     38.5     52     77
GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW.
28P68644    428   FIXC_ECOLI Protein fixC OS=Escherichia coli (...310.13     38.5     52     77
GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
GO:0009437; P:carnitine metabolic process; IEP:EcoliWiki.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW.
29P68645    428   FIXC_ECOL6 Protein fixC OS=Escherichia coli O...310.13     38.5     52     77
GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW.
30Q7AHT0    428   FIXC_ECO57 Protein fixC OS=Escherichia coli O...310.14     38.5     52     77
GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW.
31Q8ZRW9    428   FIXC_SALTY Protein fixC OS=Salmonella typhimu...310.14     38.1     52     77
GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW.
records
Previous ‹‹ ›› Next Total records: 150 1 - 30
Elimate unknown annotation:
Filter for keyword on hit description:
Select upper E value:
Select lower bit score:
Select lower %idenity value:
Select lower %positive value:
Taxonomic division:
Lower limit on hit length:
Lower limit on alignment length::