rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
1 | P39935 | 952 | IF4F1_YEAST Eukaryotic initiation factor 4F s... | 952 | 0 | 1964 | 100 | 100 | GO:0010494; C:cytoplasmic stress granule; IDA:SGD.::GO:0016281; C:eukaryotic translation initiation factor 4F complex; IMP:SGD.::GO:0005739; C:mitochondrion; IDA:SGD.::GO:0005840; C:ribosome; TAS:SGD. | | | | | | | | | | GO:0005515; F:protein binding; IPI:IntAct.::GO:0003743; F:translation initiation factor activity; TAS:SGD. | | | | | | | | | | GO:0006417; P:regulation of translation; IEA:UniProtKB-KW.::GO:0042273; P:ribosomal large subunit biogenesis; IMP:SGD.::GO:0016070; P:RNA metabolic process; IEA:InterPro.::GO:0034063; P:stress granule assembly; IMP:SGD. | 2 | P39936 | 914 | IF4F2_YEAST Eukaryotic initiation factor 4F s... | 565 | 0 | 733 | 68 | 78 | GO:0010494; C:cytoplasmic stress granule; IDA:SGD.::GO:0016281; C:eukaryotic translation initiation factor 4F complex; IGI:SGD.::GO:0005840; C:ribosome; TAS:SGD. | | | | | | | | | | GO:0005515; F:protein binding; IPI:IntAct.::GO:0003743; F:translation initiation factor activity; TAS:SGD. | | | | | | | | | | GO:0006417; P:regulation of translation; IEA:UniProtKB-KW.::GO:0016070; P:RNA metabolic process; IEA:InterPro.::GO:0034063; P:stress granule assembly; IMP:SGD. | 3 | Q10475 | 1403 | IF4G_SCHPO Eukaryotic translation initiation ... | 353 | 1e-68 | 254 | 42 | 59 | GO:0005829; C:cytosol; IDA:PomBase.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005515; F:protein binding; IPI:PomBase.::GO:0005198; F:structural molecule activity; TAS:PomBase.::GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0002183; P:cytoplasmic translational initiation; NAS:PomBase.::GO:0042273; P:ribosomal large subunit biogenesis; ISS:PomBase.::GO:0016070; P:RNA metabolic process; IEA:InterPro. | 4 | Q80XI3 | 1579 | IF4G3_MOUSE Eukaryotic translation initiation... | 296 | 1e-32 | 141 | 33 | 52 | | | | | | | | | | | GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007128; P:meiotic prophase I; IMP:MGI.::GO:0001934; P:positive regulation of protein phosphorylation; IMP:MGI.::GO:0045727; P:positive regulation of translation; IMP:MGI.::GO:0016070; P:RNA metabolic process; IEA:InterPro.::GO:0007283; P:spermatogenesis; IMP:MGI. | 5 | O43432 | 1585 | IF4G3_HUMAN Eukaryotic translation initiation... | 296 | 3e-32 | 139 | 33 | 52 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0016281; C:eukaryotic translation initiation factor 4F complex; TAS:ProtInc. | | | | | | | | | | GO:0005488; F:binding; IEA:InterPro.::GO:0000339; F:RNA cap binding; TAS:ProtInc.::GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.::GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW.::GO:0006446; P:regulation of translational initiation; TAS:ProtInc.::GO:0016070; P:RNA metabolic process; IEA:InterPro. | 6 | Q04637 | 1599 | IF4G1_HUMAN Eukaryotic translation initiation... | 310 | 1e-31 | 137 | 33 | 49 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0016281; C:eukaryotic translation initiation factor 4F complex; TAS:ProtInc. | | | | | | | | | | GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0003743; F:translation initiation factor activity; TAS:UniProtKB. | | | | | | | | | | GO:0008219; P:cell death; IEA:UniProtKB-KW.::GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.::GO:0008286; P:insulin receptor signaling pathway; TAS:Reactome.::GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW.::GO:0000184; P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; TAS:Reactome.::GO:0000289; P:nuclear-transcribed mRNA poly(A) tail shortening; TAS:Reactome.::GO:0006446; P:regulation of translational initiation; IMP:UniProtKB. | 7 | Q6NZJ6 | 1600 | IF4G1_MOUSE Eukaryotic translation initiation... | 310 | 2e-31 | 137 | 34 | 49 | GO:0005737; C:cytoplasm; IDA:MGI. | | | | | | | | | | GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0016070; P:RNA metabolic process; IEA:InterPro. | 8 | Q76E23 | 1727 | IF4G1_ARATH Eukaryotic translation initiation... | 490 | 1e-26 | 121 | 27 | 43 | | | | | | | | | | | GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006417; P:regulation of translation; IEA:UniProtKB-KW.::GO:0016070; P:RNA metabolic process; IEA:InterPro. | 9 | Q62448 | 906 | IF4G2_MOUSE Eukaryotic translation initiation... | 303 | 1e-21 | 104 | 29 | 51 | GO:0016281; C:eukaryotic translation initiation factor 4F complex; ISS:UniProtKB. | | | | | | | | | | GO:0005515; F:protein binding; IPI:IntAct.::GO:0003743; F:translation initiation factor activity; IDA:UniProtKB. | | | | | | | | | | GO:0006446; P:regulation of translational initiation; IDA:UniProtKB.::GO:0016070; P:RNA metabolic process; IEA:InterPro. | 10 | P79398 | 907 | IF4G2_RABIT Eukaryotic translation initiation... | 304 | 2e-21 | 104 | 29 | 51 | GO:0016281; C:eukaryotic translation initiation factor 4F complex; ISS:UniProtKB. | | | | | | | | | | GO:0003743; F:translation initiation factor activity; IDA:UniProtKB. | | | | | | | | | | GO:0006446; P:regulation of translational initiation; IDA:UniProtKB.::GO:0016070; P:RNA metabolic process; IEA:InterPro. | 11 | Q03387 | 788 | IF41_WHEAT Eukaryotic initiation factor iso-4... | 294 | 2e-21 | 104 | 28 | 49 | | | | | | | | | | | GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0016070; P:RNA metabolic process; IEA:InterPro. | 12 | Q5R7J9 | 907 | IF4G2_PONAB Eukaryotic translation initiation... | 304 | 2e-21 | 104 | 30 | 52 | GO:0016281; C:eukaryotic translation initiation factor 4F complex; ISS:UniProtKB. | | | | | | | | | | GO:0003743; F:translation initiation factor activity; ISS:UniProtKB. | | | | | | | | | | GO:0006446; P:regulation of translational initiation; ISS:UniProtKB.::GO:0016070; P:RNA metabolic process; IEA:InterPro. | 13 | P78344 | 907 | IF4G2_HUMAN Eukaryotic translation initiation... | 304 | 2e-21 | 104 | 30 | 52 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0016281; C:eukaryotic translation initiation factor 4F complex; IDA:UniProtKB. | | | | | | | | | | GO:0005515; F:protein binding; IPI:IntAct.::GO:0003743; F:translation initiation factor activity; IDA:UniProtKB. | | | | | | | | | | GO:0007050; P:cell cycle arrest; TAS:ProtInc.::GO:0008219; P:cell death; TAS:ProtInc.::GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.::GO:0006446; P:regulation of translational initiation; IDA:UniProtKB.::GO:0016070; P:RNA metabolic process; IEA:InterPro. | 14 | Q95L46 | 907 | IF4G2_BOVIN Eukaryotic translation initiation... | 304 | 2e-21 | 104 | 30 | 52 | GO:0016281; C:eukaryotic translation initiation factor 4F complex; ISS:UniProtKB. | | | | | | | | | | GO:0003743; F:translation initiation factor activity; ISS:UniProtKB. | | | | | | | | | | GO:0006446; P:regulation of translational initiation; ISS:UniProtKB.::GO:0016070; P:RNA metabolic process; IEA:InterPro. | 15 | P41110 | 1402 | IF4G1_RABIT Eukaryotic translation initiation... | 313 | 3e-20 | 100 | 29 | 46 | | | | | | | | | | | GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0016070; P:RNA metabolic process; IEA:InterPro. | 16 | Q553R3 | 1377 | IF4G_DICDI Eukaryotic translation initiation ... | 335 | 2e-19 | 98.2 | 26 | 47 | GO:0016281; C:eukaryotic translation initiation factor 4F complex; ISS:dictyBase. | | | | | | | | | | GO:0003743; F:translation initiation factor activity; ISS:dictyBase. | | | | | | | | | | GO:0006446; P:regulation of translational initiation; ISS:dictyBase.::GO:0016070; P:RNA metabolic process; IEA:InterPro. | 17 | C7G046 | 2079 | Y6969_DICDI von Willebrand factor A domain-co... | 250 | 0.00000000002 | 72 | 27 | 48 | | | | | | | | | | | GO:0005488; F:binding; IEA:InterPro. | | | | | | | | | | GO:0016070; P:RNA metabolic process; IEA:InterPro. | 18 | Q5Z5Q3 | 711 | C3H43_ORYSJ Zinc finger CCCH domain-containin... | 201 | 0.00003 | 51.6 | 28 | 45 | | | | | | | | | | | GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0016070; P:RNA metabolic process; IEA:InterPro. | 19 | Q8VE62 | 400 | PAIP1_MOUSE Polyadenylate-binding protein-int... | 302 | 0.00003 | 50.8 | 24 | 42 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0016070; P:RNA metabolic process; IEA:InterPro. | 20 | Q9H074 | 479 | PAIP1_HUMAN Polyadenylate-binding protein-int... | 305 | 0.0003 | 48.1 | 24 | 43 | GO:0005829; C:cytosol; TAS:Reactome. | | | | | | | | | | GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0003723; F:RNA binding; TAS:ProtInc.::GO:0008494; F:translation activator activity; IDA:UniProtKB. | | | | | | | | | | GO:0048255; P:mRNA stabilization; TAS:UniProtKB.::GO:0000289; P:nuclear-transcribed mRNA poly(A) tail shortening; TAS:Reactome.::GO:0006413; P:translational initiation; TAS:ProtInc. | 21 | Q8SVP8 | 627 | IF4G_ENCCU Probable eukaryotic translation in... | 59 | 0.1 | 40 | 39 | 56 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006417; P:regulation of translation; IEA:UniProtKB-KW.::GO:0016070; P:RNA metabolic process; IEA:InterPro. | 22 | Q9BXK5 | 485 | B2L13_HUMAN Bcl-2-like protein 13 OS=Homo sap... | 101 | 0.46 | 37.7 | 26 | 47 | GO:0016021; C:integral to membrane; IDA:UniProtKB.::GO:0031966; C:mitochondrial membrane; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008656; F:cysteine-type endopeptidase activator activity involved in apoptotic process; NAS:UniProtKB. | | | | | | | | | | GO:0006917; P:induction of apoptosis; NAS:UniProtKB. | 23 | C4V8K5 | 598 | IF4G_NOSCE Probable eukaryotic translation in... | 217 | 4.9 | 34.7 | 22 | 42 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006417; P:regulation of translation; IEA:UniProtKB-KW.::GO:0016070; P:RNA metabolic process; IEA:InterPro. | 24 | O70437 | 552 | SMAD4_RAT Mothers against decapentaplegic hom... | 65 | 5.5 | 34.3 | 31 | 45 | | | | | | | | | | | | | | | | | | | | | GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 25 | P97471 | 551 | SMAD4_MOUSE Mothers against decapentaplegic h... | 65 | 5.5 | 34.3 | 31 | 45 | | | | | | | | | | | GO:0003682; F:chromatin binding; IDA:MGI.::GO:0005518; F:collagen binding; IPI:MGI.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:MGI. | | | | | | | | | | GO:0008283; P:cell proliferation; IMP:MGI.::GO:0048589; P:developmental growth; IMP:MGI.::GO:0007492; P:endoderm development; IMP:MGI.::GO:0048859; P:formation of anatomical boundary; IMP:MGI.::GO:0001702; P:gastrulation with mouth forming second; IMP:MGI.::GO:0001701; P:in utero embryonic development; IMP:MGI.::GO:0007498; P:mesoderm development; IMP:MGI.::GO:0072133; P:metanephric mesenchyme morphogenesis; IMP:UniProtKB.::GO:0060548; P:negative regulation of cell death; IMP:UniProtKB.::GO:0008285; P:negative regulation of cell proliferation; IGI:MGI.::GO:0072134; P:nephrogenic mesenchyme morphogenesis; IMP:UniProtKB.::GO:0014033; P:neural crest cell differentiation; IMP:MGI.::GO:0048663; P:neuron fate commitment; IMP:MGI.::GO:0060021; P:palate development; IMP:BHF-UCL.::GO:0010718; P:positive regulation of epithelial to mesenchymal transition; IMP:BHF-UCL.::GO:0010862; P:positive regulation of pathway-restricted SMAD protein phosphorylation; IMP:BHF-UCL.::GO:0060391; P:positive regulation of SMAD protein import into nucleus; IMP:BHF-UCL.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:MGI.::GO:0051098; P:regulation of binding; IDA:MGI.::GO:0051797; P:regulation of hair follicle development; IMP:MGI.::GO:0048733; P:sebaceous gland development; IMP:MGI.::GO:0032525; P:somite rostral/caudal axis specification; IMP:MGI.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 26 | Q1HE26 | 553 | SMAD4_BOVIN Mothers against decapentaplegic h... | 65 | 6.8 | 34.3 | 31 | 45 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005667; C:transcription factor complex; IEA:InterPro. | | | | | | | | | | GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro. | | | | | | | | | | GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0007179; P:transforming growth factor beta receptor signaling pathway; IEA:InterPro. | 27 | O88799 | 5376 | ZAN_MOUSE Zonadhesin OS=Mus musculus (Mouse).... | 278 | 7.8 | 34.3 | 24 | 35 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0007155; P:cell adhesion; IEA:UniProtKB-KW. | 28 | B0KL24 | 626 | THIC_PSEPG Phosphomethylpyrimidine synthase O... | 70 | 8.2 | 33.9 | 33 | 46 | | | | | | | | | | | GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0016829; F:lyase activity; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009228; P:thiamine biosynthetic process; IEA:UniProtKB-KW. | 29 | Q13485 | 552 | SMAD4_HUMAN Mothers against decapentaplegic h... | 65 | 8.7 | 33.9 | 31 | 43 | GO:0032444; C:activin responsive factor complex; IDA:BHF-UCL.::GO:0005813; C:centrosome; IDA:HPA.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0071141; C:SMAD protein complex; IDA:UniProtKB. | | | | | | | | | | GO:0000987; F:core promoter proximal region sequence-specific DNA binding; IDA:UniProtKB.::GO:0070411; F:I-SMAD binding; IPI:BHF-UCL.::GO:0042803; F:protein homodimerization activity; IPI:BHF-UCL.::GO:0070412; F:R-SMAD binding; IPI:BHF-UCL.::GO:0030616; F:transforming growth factor beta receptor, common-partner cytoplasmic mediator activity; IDA:BHF-UCL. | | | | | | | | | | GO:0030509; P:BMP signaling pathway; IDA:BHF-UCL.::GO:0030308; P:negative regulation of cell growth; IDA:BHF-UCL.::GO:0042177; P:negative regulation of protein catabolic process; IMP:BHF-UCL.::GO:0045892; P:negative regulation of transcription, DNA-dependent; IDA:BHF-UCL.::GO:0060021; P:palate development; ISS:BHF-UCL.::GO:0030513; P:positive regulation of BMP signaling pathway; IMP:BHF-UCL.::GO:0010718; P:positive regulation of epithelial to mesenchymal transition; ISS:BHF-UCL.::GO:0010862; P:positive regulation of pathway-restricted SMAD protein phosphorylation; ISS:BHF-UCL.::GO:0060391; P:positive regulation of SMAD protein import into nucleus; ISS:BHF-UCL.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.::GO:0030511; P:positive regulation of transforming growth factor beta receptor signaling pathway; IDA:BHF-UCL.::GO:0032909; P:regulation of transforming growth factor beta2 production; IMP:BHF-UCL.::GO:0001666; P:response to hypoxia; IMP:BHF-UCL.::GO:0071559; P:response to transforming growth factor beta stimulus; IDA:UniProtKB.::GO:0007183; P:SMAD protein complex assembly; IDA:BHF-UCL.::GO:0060395; P:SMAD protein signal transduction; IDA:BHF-UCL.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0007179; P:transforming growth factor beta receptor signaling pathway; IDA:BHF-UCL. | 30 | Q008X6 | 6872 | R1AB_WBV24 Replicase polyprotein 1ab OS=White... | 194 | 10 | 33.9 | 21 | 36 | GO:0033644; C:host cell membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004197; F:cysteine-type endopeptidase activity; IEA:InterPro.::GO:0004519; F:endonuclease activity; IEA:UniProtKB-KW.::GO:0016896; F:exoribonuclease activity, producing 5'-phosphomonoesters; IEA:InterPro.::GO:0004386; F:helicase activity; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0008168; F:methyltransferase activity; IEA:InterPro.::GO:0003968; F:RNA-directed RNA polymerase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW.::GO:0032774; P:RNA biosynthetic process; IEA:UniProtKB-KW. |