UniProt_SwissProt BLAST: Single locus

Species:

Saccharomyces cerevisiae S288C

Locus:

YGR158C

Length:

250

Number of sequences:

5887

Description:

YGR158C MTR3 SGDID:S000003390, Chr VII from 806021-805269, Genome Release 64-1-1, reverse complement, Verified ORF, "Exosome non-catalytic core component; involved in 3'-5' RNA processing and degradation in both the nucleus and the cytoplasm; has similarity to E. coli RNase PH and to human hMtr3p (EXOSC6)"

rec.	Subject	Hit Length	Description	Align.Len	E value	Bit score	% ident.	% pos.	GO associations
1	P48240	250	MTR3_YEAST Exosome complex component MTR3 OS=...	250	0	520	100	100	GO:0000177; C:cytoplasmic exosome (RNase complex); IDA:SGD.::GO:0000176; C:nuclear exosome (RNase complex); IDA:SGD.::GO:0005730; C:nucleolus; IDA:SGD.
									GO:0005515; F:protein binding; IPI:IntAct.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
									GO:0000467; P:exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); IMP:SGD.::GO:0070651; P:nonfunctional rRNA decay; IC:SGD.::GO:0071028; P:nuclear mRNA surveillance; IMP:SGD.::GO:0071039; P:nuclear polyadenylation-dependent CUT catabolic process; IMP:SGD.::GO:0071042; P:nuclear polyadenylation-dependent mRNA catabolic process; IC:SGD.::GO:0071035; P:nuclear polyadenylation-dependent rRNA catabolic process; IMP:SGD.::GO:0071038; P:nuclear polyadenylation-dependent tRNA catabolic process; IDA:SGD.::GO:0070478; P:nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay; IC:SGD.::GO:0070481; P:nuclear-transcribed mRNA catabolic process, non-stop decay; IC:SGD.::GO:0071051; P:polyadenylation-dependent snoRNA 3'-end processing; IMP:SGD.::GO:0034475; P:U4 snRNA 3'-end processing; IMP:SGD.
2	B1Y978	246	ECX1_THENV Probable exosome complex exonuclea...	180	0.00000001	57.4	28	47	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0000178; C:exosome (RNase complex); IEA:UniProtKB-KW.
									GO:0016896; F:exoribonuclease activity, producing 5'-phosphomonoesters; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:InterPro.
									GO:0006396; P:RNA processing; IEA:InterPro.
3	Q6P0I8	271	EXOS6_DANRE Exosome complex component MTR3 OS...	272	0.00000002	57	23	39	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0000178; C:exosome (RNase complex); ISS:UniProtKB.::GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
									GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
									GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
4	Q8U0L9	250	ECX1_PYRFU Probable exosome complex exonuclea...	168	0.00000007	55.5	25	43	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0000178; C:exosome (RNase complex); IEA:UniProtKB-KW.
									GO:0016896; F:exoribonuclease activity, producing 5'-phosphomonoesters; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:InterPro.
									GO:0006396; P:RNA processing; IEA:InterPro.
5	A1RST0	246	ECX1_PYRIL Probable exosome complex exonuclea...	177	0.0000001	54.3	28	46	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0000178; C:exosome (RNase complex); IEA:UniProtKB-KW.
									GO:0016896; F:exoribonuclease activity, producing 5'-phosphomonoesters; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:InterPro.
									GO:0006396; P:RNA processing; IEA:InterPro.
6	Q9V119	249	ECX1_PYRAB Probable exosome complex exonuclea...	168	0.0000001	54.3	24	43	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0000178; C:exosome (RNase complex); IEA:UniProtKB-KW.
									GO:0000175; F:3'-5'-exoribonuclease activity; IEA:HAMAP.::GO:0016896; F:exoribonuclease activity, producing 5'-phosphomonoesters; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:InterPro.
									GO:0006401; P:RNA catabolic process; IEA:HAMAP.::GO:0006396; P:RNA processing; IEA:InterPro.
7	O59223	249	ECX1_PYRHO Probable exosome complex exonuclea...	168	0.0000002	54.3	24	43	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0000178; C:exosome (RNase complex); IEA:UniProtKB-KW.
									GO:0016896; F:exoribonuclease activity, producing 5'-phosphomonoesters; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:InterPro.
									GO:0006396; P:RNA processing; IEA:InterPro.
8	B6YSI2	249	ECX1_THEON Probable exosome complex exonuclea...	170	0.0000003	53.9	25	44	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0000178; C:exosome (RNase complex); IEA:UniProtKB-KW.
									GO:0016896; F:exoribonuclease activity, producing 5'-phosphomonoesters; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:InterPro.
									GO:0006396; P:RNA processing; IEA:InterPro.
9	Q5JIR6	249	ECX1_PYRKO Probable exosome complex exonuclea...	170	0.0000003	53.5	24	44	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0000178; C:exosome (RNase complex); IEA:UniProtKB-KW.
									GO:0016896; F:exoribonuclease activity, producing 5'-phosphomonoesters; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:InterPro.
									GO:0006396; P:RNA processing; IEA:InterPro.
10	Q28F19	270	EXOS6_XENTR Exosome complex component MTR3 OS...	238	0.0000004	53.5	25	41	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0000178; C:exosome (RNase complex); ISS:UniProtKB.::GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
									GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
									GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
11	Q8ZVM9	246	ECX1_PYRAE Probable exosome complex exonuclea...	159	0.0000004	53.1	28	48	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0000178; C:exosome (RNase complex); IEA:UniProtKB-KW.
									GO:0016896; F:exoribonuclease activity, producing 5'-phosphomonoesters; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:InterPro.
									GO:0006396; P:RNA processing; IEA:InterPro.
12	A4WM67	246	ECX1_PYRAR Probable exosome complex exonuclea...	159	0.0000004	53.1	28	48	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0000178; C:exosome (RNase complex); IEA:UniProtKB-KW.
									GO:0016896; F:exoribonuclease activity, producing 5'-phosphomonoesters; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:InterPro.
									GO:0006396; P:RNA processing; IEA:InterPro.
13	A3MUP1	246	ECX1_PYRCJ Probable exosome complex exonuclea...	159	0.0000005	52.8	28	48	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0000178; C:exosome (RNase complex); IEA:UniProtKB-KW.
									GO:0016896; F:exoribonuclease activity, producing 5'-phosphomonoesters; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:InterPro.
									GO:0006396; P:RNA processing; IEA:InterPro.
14	Q9UXC2	248	ECX1_SULSO Probable exosome complex exonuclea...	181	0.000002	51.2	24	46	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0000178; C:exosome (RNase complex); IEA:UniProtKB-KW.
									GO:0016896; F:exoribonuclease activity, producing 5'-phosphomonoesters; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:InterPro.
									GO:0006396; P:RNA processing; IEA:InterPro.
15	C5A2B9	249	ECX1_THEGJ Probable exosome complex exonuclea...	170	0.000002	51.2	22	45	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0000178; C:exosome (RNase complex); IEA:UniProtKB-KW.
									GO:0016896; F:exoribonuclease activity, producing 5'-phosphomonoesters; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:InterPro.
									GO:0006396; P:RNA processing; IEA:InterPro.
16	A2BKC0	255	ECX1_HYPBU Probable exosome complex exonuclea...	169	0.000007	49.7	27	41	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0000178; C:exosome (RNase complex); IEA:UniProtKB-KW.
									GO:0016896; F:exoribonuclease activity, producing 5'-phosphomonoesters; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:InterPro.
									GO:0006396; P:RNA processing; IEA:InterPro.
17	Q975G8	243	ECX1_SULTO Probable exosome complex exonuclea...	181	0.00002	48.1	22	48	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0000178; C:exosome (RNase complex); IEA:UniProtKB-KW.
									GO:0016896; F:exoribonuclease activity, producing 5'-phosphomonoesters; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:InterPro.
									GO:0006396; P:RNA processing; IEA:InterPro.
18	Q9YC03	246	ECX1_AERPE Probable exosome complex exonuclea...	187	0.00003	47.8	24	42	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0000178; C:exosome (RNase complex); IEA:UniProtKB-KW.
									GO:0016896; F:exoribonuclease activity, producing 5'-phosphomonoesters; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:InterPro.
									GO:0006396; P:RNA processing; IEA:InterPro.
19	Q8TYC1	239	ECX1_METKA Probable exosome complex exonuclea...	170	0.00003	47.4	24	42	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0000178; C:exosome (RNase complex); IEA:UniProtKB-KW.
									GO:0016896; F:exoribonuclease activity, producing 5'-phosphomonoesters; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:InterPro.
									GO:0006396; P:RNA processing; IEA:InterPro.
20	A9A5C9	244	ECX1_NITMS Probable exosome complex exonuclea...	181	0.00004	47.4	23	43	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0000178; C:exosome (RNase complex); IEA:UniProtKB-KW.
									GO:0016896; F:exoribonuclease activity, producing 5'-phosphomonoesters; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:InterPro.
									GO:0006396; P:RNA processing; IEA:InterPro.
21	A8WQQ5	240	EXOS4_CAEBR Putative exosome complex componen...	159	0.0008	43.5	25	40	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0000178; C:exosome (RNase complex); IEA:UniProtKB-KW.::GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
									GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
									GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
22	Q7YRA3	245	EXOS4_BOVIN Exosome complex component RRP41 O...	186	0.001	42.7	25	41	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0000178; C:exosome (RNase complex); ISS:UniProtKB.::GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
									GO:0004527; F:exonuclease activity; IEA:UniProtKB-KW.
									GO:0071044; P:histone mRNA catabolic process; ISS:UniProtKB.
23	Q921I9	245	EXOS4_MOUSE Exosome complex component RRP41 O...	186	0.001	42.7	24	40	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0000178; C:exosome (RNase complex); ISS:UniProtKB.::GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
									GO:0005515; F:protein binding; IPI:MGI.
									GO:0071044; P:histone mRNA catabolic process; ISS:UniProtKB.
24	Q9NPD3	245	EXOS4_HUMAN Exosome complex component RRP41 O...	186	0.001	42.7	25	41	GO:0005829; C:cytosol; TAS:Reactome.::GO:0000178; C:exosome (RNase complex); IDA:UniProtKB.::GO:0005730; C:nucleolus; NAS:UniProtKB.::GO:0035327; C:transcriptionally active chromatin; IMP:UniProtKB.
									GO:0000175; F:3'-5'-exoribonuclease activity; NAS:UniProtKB.::GO:0017091; F:AU-rich element binding; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:UniProtKB.
									GO:0051607; P:defense response to virus; IMP:MGI.::GO:0045006; P:DNA deamination; IDA:UniProtKB.::GO:0043928; P:exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay; TAS:Reactome.::GO:0071044; P:histone mRNA catabolic process; IMP:UniProtKB.::GO:0000460; P:maturation of 5.8S rRNA; IMP:UniProtKB.::GO:0071028; P:nuclear mRNA surveillance; IMP:UniProtKB.::GO:0030307; P:positive regulation of cell growth; IMP:UniProtKB.
25	Q17533	240	EXOS4_CAEEL Putative exosome complex componen...	153	0.002	42	27	41	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0000178; C:exosome (RNase complex); IEA:UniProtKB-KW.::GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
									GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
									GO:0010171; P:body morphogenesis; IMP:WormBase.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0008406; P:gonad development; IMP:WormBase.::GO:0040007; P:growth; IMP:WormBase.::GO:0002119; P:nematode larval development; IMP:WormBase.::GO:0040010; P:positive regulation of growth rate; IMP:WormBase.::GO:0040018; P:positive regulation of multicellular organism growth; IMP:WormBase.::GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
26	O29757	258	ECX1_ARCFU Probable exosome complex exonuclea...	168	0.009	40	22	42	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0000178; C:exosome (RNase complex); IEA:UniProtKB-KW.
									GO:0016896; F:exoribonuclease activity, producing 5'-phosphomonoesters; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:InterPro.
									GO:0006396; P:RNA processing; IEA:InterPro.
27	Q97BZ5	248	ECX1_THEVO Probable exosome complex exonuclea...	168	0.02	38.9	22	43	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0000178; C:exosome (RNase complex); IEA:UniProtKB-KW.
									GO:0016896; F:exoribonuclease activity, producing 5'-phosphomonoesters; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:InterPro.
									GO:0006396; P:RNA processing; IEA:InterPro.
28	Q9HIP2	248	ECX1_THEAC Probable exosome complex exonuclea...	233	0.022	38.9	20	41	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0000178; C:exosome (RNase complex); IEA:UniProtKB-KW.
									GO:0016896; F:exoribonuclease activity, producing 5'-phosphomonoesters; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:InterPro.
									GO:0006396; P:RNA processing; IEA:InterPro.
29	Q4JB27	243	ECX1_SULAC Probable exosome complex exonuclea...	108	0.036	38.1	24	52	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0000178; C:exosome (RNase complex); IEA:UniProtKB-KW.
									GO:0016896; F:exoribonuclease activity, producing 5'-phosphomonoesters; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:InterPro.
									GO:0006396; P:RNA processing; IEA:InterPro.
30	Q9P7R3	257	MTR3_SCHPO Exosome complex component mtr3 OS=...	147	0.23	35.8	22	44	GO:0000177; C:cytoplasmic exosome (RNase complex); ISS:PomBase.::GO:0005829; C:cytosol; IDA:PomBase.::GO:0000176; C:nuclear exosome (RNase complex); ISS:PomBase.::GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
									GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
									GO:0000467; P:exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); ISS:PomBase.::GO:0070651; P:nonfunctional rRNA decay; ISS:PomBase.::GO:0071042; P:nuclear polyadenylation-dependent mRNA catabolic process; ISS:PomBase.::GO:0071035; P:nuclear polyadenylation-dependent rRNA catabolic process; ISS:PomBase.::GO:0071038; P:nuclear polyadenylation-dependent tRNA catabolic process; ISS:PomBase.::GO:0070478; P:nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay; ISS:PomBase.::GO:0070481; P:nuclear-transcribed mRNA catabolic process, non-stop decay; ISS:PomBase.
31	P46948	246	RRP41_YEAST Exosome complex component SKI6 OS...	128	0.79	34.3	25	42	GO:0000177; C:cytoplasmic exosome (RNase complex); IDA:SGD.::GO:0000176; C:nuclear exosome (RNase complex); IDA:SGD.::GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
									GO:0005515; F:protein binding; IPI:IntAct.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
									GO:0000467; P:exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); IMP:SGD.::GO:0070651; P:nonfunctional rRNA decay; IC:SGD.::GO:0071028; P:nuclear mRNA surveillance; IMP:SGD.::GO:0071039; P:nuclear polyadenylation-dependent CUT catabolic process; IMP:SGD.::GO:0071042; P:nuclear polyadenylation-dependent mRNA catabolic process; IC:SGD.::GO:0071038; P:nuclear polyadenylation-dependent tRNA catabolic process; IDA:SGD.::GO:0070478; P:nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay; IMP:SGD.::GO:0070481; P:nuclear-transcribed mRNA catabolic process, non-stop decay; IC:SGD.::GO:0071051; P:polyadenylation-dependent snoRNA 3'-end processing; IMP:SGD.::GO:0034473; P:U1 snRNA 3'-end processing; IMP:SGD.::GO:0034475; P:U4 snRNA 3'-end processing; IMP:SGD.::GO:0034476; P:U5 snRNA 3'-end processing; IMP:SGD.

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