UniProt_SwissProt BLAST: Single locus

Species:

Saccharomyces cerevisiae S288C

Locus:

YGR155W

Length:

507

Number of sequences:

5887

Description:

YGR155W CYS4 SGDID:S000003387, Chr VII from 798543-800066, Genome Release 64-1-1, Verified ORF, "Cystathionine beta-synthase, catalyzes synthesis of cystathionine from serine and homocysteine, the first committed step in cysteine biosynthesis; responsible for hydrogen sulfide generation; mutations in human ortholog cause homocystinuria"

rec.	Subject	Hit Length	Description	Align.Len	E value	Bit score	% ident.	% pos.	GO associations
121	Q8CNK9	422	ILVA_STAES L-threonine dehydratase biosynthet...	165	0.042	40	27	44
									GO:0004794; F:L-threonine ammonia-lyase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
									GO:0009097; P:isoleucine biosynthetic process; IEA:UniProtKB-KW.::GO:0006566; P:threonine metabolic process; ISS:UniProtKB.
122	Q5HMF5	422	ILVA_STAEQ L-threonine dehydratase biosynthet...	165	0.042	40	27	44
									GO:0004794; F:L-threonine ammonia-lyase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
									GO:0009097; P:isoleucine biosynthetic process; IEA:UniProtKB-KW.::GO:0006566; P:threonine metabolic process; ISS:UniProtKB.
123	A1RVT1	420	TRPB_PYRIL Tryptophan synthase beta chain OS=...	111	0.05	39.7	27	47
									GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0004834; F:tryptophan synthase activity; IEA:EC.
124	P46493	513	ILVA_HAEIN L-threonine dehydratase biosynthet...	104	0.054	39.7	28	47
									GO:0004794; F:L-threonine ammonia-lyase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
									GO:0009097; P:isoleucine biosynthetic process; IEA:UniProtKB-KW.::GO:0006566; P:threonine metabolic process; ISS:UniProtKB.
125	P0CF23	338	SDH1_YEASX L-serine dehydratase OS=Saccharomy...	199	0.058	39.3	23	42	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0003941; F:L-serine ammonia-lyase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
									GO:0006520; P:cellular amino acid metabolic process; IEA:InterPro.::GO:0006094; P:gluconeogenesis; IEA:UniProtKB-KW.
126	A4WKQ9	409	TRPB_PYRAR Tryptophan synthase beta chain OS=...	111	0.065	39.3	26	50
									GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0004834; F:tryptophan synthase activity; IEA:EC.
127	Q57647	265	Y188_METJA Uncharacterized protein MJ0188 OS=...	79	4.7	33.1	28	51
									GO:0003824; F:catalytic activity; IEA:InterPro.::GO:0003677; F:DNA binding; IEA:InterPro.
128	A0R220	360	THRC_MYCS2 Threonine synthase OS=Mycobacteriu...	118	0.072	39.3	31	48
									GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0004795; F:threonine synthase activity; IEA:EC.
									GO:0009088; P:threonine biosynthetic process; IEA:UniProtKB-KW.
129	Q10725	326	FSDH_BURPI Phenylserine dehydratase OS=Burkho...	188	0.082	38.9	23	41
									GO:0016829; F:lyase activity; IDA:UniProtKB.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
130	Q57564	509	Y100_METJA Uncharacterized protein MJ0100 OS=...	84	0.14	38.5	26	50
									GO:0003824; F:catalytic activity; IEA:InterPro.
131	Q9HLK8	485	IMDH_THEAC Inosine-5'-monophosphate dehydroge...	102	0.15	38.5	23	51
									GO:0003938; F:IMP dehydrogenase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
									GO:0006177; P:GMP biosynthetic process; IEA:UniProtKB-KW.
132	P55664	332	Y4TJ_RHISN Putative threonine dehydratase OS=...	114	0.18	37.7	29	46
									GO:0004794; F:L-threonine ammonia-lyase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
									GO:0009097; P:isoleucine biosynthetic process; IEA:UniProtKB-KW.
133	O23193	236	CBSX1_ARATH CBS domain-containing protein CBS...	59	1.8	34.3	39	58	GO:0009507; C:chloroplast; IDA:TAIR.
									GO:0045454; P:cell redox homeostasis; IDA:TAIR.
134	P20506	514	ILVA_SALTY L-Threonine dehydratase biosynthet...	118	0.21	37.7	29	47
									GO:0004794; F:L-threonine ammonia-lyase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
									GO:0009097; P:isoleucine biosynthetic process; IEA:UniProtKB-KW.::GO:0006566; P:threonine metabolic process; ISS:UniProtKB.
135	Q75TH5	459	SDHD_GEOSE Probable D-serine dehydratase OS=G...	112	0.25	37.7	25	48
									GO:0008721; F:D-serine ammonia-lyase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
									GO:0046416; P:D-amino acid metabolic process; IEA:InterPro.
136	P74193	382	THRC_SYNY3 Threonine synthase OS=Synechocysti...	78	0.27	37.4	32	50
									GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0004795; F:threonine synthase activity; IEA:EC.
									GO:0009088; P:threonine biosynthetic process; IEA:UniProtKB-KW.
137	Q75TC9	441	SDHD_GEOKA Probable D-serine dehydratase OS=G...	112	0.28	37.4	25	48
									GO:0008721; F:D-serine ammonia-lyase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
									GO:0046416; P:D-amino acid metabolic process; IEA:InterPro.
138	O27520	429	TRPB2_METTH Tryptophan synthase beta chain 2 ...	273	0.3	37.4	22	38
									GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0004834; F:tryptophan synthase activity; IEA:EC.
139	P36007	326	SRY1_YEAST Threo-3-hydroxyaspartate ammonia-l...	117	0.34	37	29	44
									GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0030848; F:threo-3-hydroxyaspartate ammonia-lyase activity; IMP:SGD.
									GO:0042219; P:cellular modified amino acid catabolic process; IDA:SGD.
140	A5IZD7	170	APT_MYCAP Adenine phosphoribosyltransferase O...	96	0.39	35.8	32	45	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0003999; F:adenine phosphoribosyltransferase activity; IEA:EC.
									GO:0006168; P:adenine salvage; IEA:InterPro.::GO:0006166; P:purine ribonucleoside salvage; IEA:UniProtKB-KW.
141	Q57368	299	CORC_HAEIN Magnesium and cobalt efflux protei...	60	0.4	36.6	37	60
									GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.
									GO:0006810; P:transport; IEA:UniProtKB-KW.
142	Q76EQ0	333	SRR_RAT Serine racemase OS=Rattus norvegicus ...	297	0.42	36.6	27	42	GO:0045177; C:apical part of cell; IDA:RGD.::GO:0005737; C:cytoplasm; IDA:RGD.::GO:0005886; C:plasma membrane; IDA:RGD.
									GO:0005524; F:ATP binding; IDA:UniProtKB.::GO:0008721; F:D-serine ammonia-lyase activity; IEA:EC.::GO:0003941; F:L-serine ammonia-lyase activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IDA:UniProtKB.::GO:0042803; F:protein homodimerization activity; IPI:UniProtKB.::GO:0030170; F:pyridoxal phosphate binding; IDA:UniProtKB.::GO:0030378; F:serine racemase activity; IDA:UniProtKB.
									GO:0007568; P:aging; IEP:RGD.::GO:0007420; P:brain development; IEP:RGD.::GO:0006563; P:L-serine metabolic process; IDA:UniProtKB.::GO:0042493; P:response to drug; IEP:RGD.::GO:0043278; P:response to morphine; IEP:RGD.
143	P04968	514	ILVA_ECOLI L-threonine dehydratase biosynthet...	118	0.42	37	29	45	GO:0005737; C:cytoplasm; IC:EcoliWiki.
									GO:0016597; F:amino acid binding; IDA:EcoliWiki.::GO:0004794; F:L-threonine ammonia-lyase activity; IDA:EcoCyc.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
									GO:0009097; P:isoleucine biosynthetic process; IDA:EcoCyc.::GO:0006566; P:threonine metabolic process; IDA:UniProtKB.
144	B7IHA8	420	TRPB_THEAB Tryptophan synthase beta chain OS=...	341	0.56	36.6	23	40
									GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0004834; F:tryptophan synthase activity; IEA:EC.
145	Q39469	590	THD1_CICAR Threonine dehydratase biosynthetic...	228	0.57	36.6	25	43	GO:0009507; C:chloroplast; IEA:UniProtKB-SubCell.
									GO:0004794; F:L-threonine ammonia-lyase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
									GO:0009097; P:isoleucine biosynthetic process; IEA:UniProtKB-KW.
146	P0A0X9	208	RS4_XANCP 30S ribosomal protein S4 OS=LMG 568...	137	0.59	35.8	29	46	GO:0015935; C:small ribosomal subunit; IEA:InterPro.
									GO:0019843; F:rRNA binding; IEA:UniProtKB-KW.::GO:0003735; F:structural constituent of ribosome; IEA:InterPro.
									GO:0006412; P:translation; IEA:InterPro.
147	B0RU59	208	RS4_XANCB 30S ribosomal protein S4 OS=Xanthom...	137	0.59	35.8	29	46	GO:0015935; C:small ribosomal subunit; IEA:InterPro.
									GO:0019843; F:rRNA binding; IEA:UniProtKB-KW.::GO:0003735; F:structural constituent of ribosome; IEA:InterPro.
									GO:0006412; P:translation; IEA:InterPro.
148	Q4URG2	208	RS4_XANC8 30S ribosomal protein S4 OS=Xanthom...	137	0.59	35.8	29	46	GO:0015935; C:small ribosomal subunit; IEA:InterPro.
									GO:0019843; F:rRNA binding; IEA:UniProtKB-KW.::GO:0003735; F:structural constituent of ribosome; IEA:InterPro.
									GO:0006412; P:translation; IEA:InterPro.
149	Q3BWW0	208	RS4_XANC5 30S ribosomal protein S4 OS=Xanthom...	137	0.59	35.8	29	46	GO:0015935; C:small ribosomal subunit; IEA:InterPro.
									GO:0019843; F:rRNA binding; IEA:UniProtKB-KW.::GO:0003735; F:structural constituent of ribosome; IEA:InterPro.
									GO:0006412; P:translation; IEA:InterPro.
150	P0A0Y0	208	RS4_XANAC 30S ribosomal protein S4 OS=Xanthom...	137	0.59	35.8	29	46	GO:0015935; C:small ribosomal subunit; IEA:InterPro.
									GO:0019843; F:rRNA binding; IEA:UniProtKB-KW.::GO:0003735; F:structural constituent of ribosome; IEA:InterPro.
									GO:0006412; P:translation; IEA:InterPro.
151	Q88TY1	436	SDHD_LACPL Probable D-serine dehydratase OS=L...	266	0.62	36.2	21	39
									GO:0008721; F:D-serine ammonia-lyase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
									GO:0046416; P:D-amino acid metabolic process; IEA:InterPro.

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