Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YGR155W
Length:
507
Number of sequences:
5887
Description:
YGR155W CYS4 SGDID:S000003387, Chr VII from 798543-800066, Genome Release 64-1-1, Verified ORF, "Cystathionine beta-synthase, catalyzes synthesis of cystathionine from serine and homocysteine, the first committed step in cysteine biosynthesis; responsible for hydrogen sulfide generation; mutations in human ortholog cause homocystinuria"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
1P32582    507   CBS_YEAST Cystathionine beta-synthase OS=Sacc...5070     1027     100     100GO:0005739; C:mitochondrion; IDA:SGD.
GO:0004122; F:cystathionine beta-synthase activity; IDA:SGD.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
GO:0006535; P:cysteine biosynthetic process from serine; IDA:SGD.::GO:0019343; P:cysteine biosynthetic process via cystathionine; IMP:SGD.::GO:0070814; P:hydrogen sulfide biosynthetic process; IDA:SGD.::GO:0019346; P:transsulfuration; IMP:SGD.::GO:0007089; P:traversing start control point of mitotic cell cycle; IMP:SGD.
2P46794    498   CBS_DICDI Cystathionine beta-synthase OS=Dict...4942e-130     395     48     63GO:0005737; C:cytoplasm; ISS:dictyBase.
GO:0004122; F:cystathionine beta-synthase activity; ISS:dictyBase.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
GO:0006535; P:cysteine biosynthetic process from serine; IEA:InterPro.::GO:0019343; P:cysteine biosynthetic process via cystathionine; IEA:InterPro.
3Q91WT9    561   CBS_MOUSE Cystathionine beta-synthase OS=Mus ...4342e-129     395     47     65
GO:0004122; F:cystathionine beta-synthase activity; IMP:MGI.
GO:0001974; P:blood vessel remodeling; IMP:MGI.::GO:0060351; P:cartilage development involved in endochondral bone morphogenesis; IMP:MGI.::GO:0021587; P:cerebellum morphogenesis; IMP:MGI.::GO:0006535; P:cysteine biosynthetic process from serine; IEA:InterPro.::GO:0019343; P:cysteine biosynthetic process via cystathionine; IEA:InterPro.::GO:0001958; P:endochondral ossification; IMP:MGI.::GO:0070814; P:hydrogen sulfide biosynthetic process; ISS:UniProtKB.::GO:0060135; P:maternal process involved in female pregnancy; IMP:MGI.::GO:0050880; P:regulation of blood vessel size; IMP:MGI.::GO:0030823; P:regulation of cGMP metabolic process; IMP:MGI.::GO:0043506; P:regulation of JUN kinase activity; IMP:MGI.::GO:0051593; P:response to folic acid; IMP:MGI.::GO:0006801; P:superoxide metabolic process; IMP:MGI.
4Q58H57    551   CBS_MACFA Cystathionine beta-synthase OS=Maca...4353e-128     391     47     66GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0004122; F:cystathionine beta-synthase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
GO:0006535; P:cysteine biosynthetic process from serine; IEA:InterPro.::GO:0019343; P:cysteine biosynthetic process via cystathionine; IEA:InterPro.::GO:0070814; P:hydrogen sulfide biosynthetic process; ISS:UniProtKB.
5P32232    561   CBS_RAT Cystathionine beta-synthase OS=Rattus...4345e-128     391     47     65GO:0005625; C:soluble fraction; IDA:RGD.
GO:0004122; F:cystathionine beta-synthase activity; IDA:RGD.::GO:0030170; F:pyridoxal phosphate binding; TAS:RGD.
GO:0071456; P:cellular response to hypoxia; IDA:UniProtKB.::GO:0006535; P:cysteine biosynthetic process from serine; TAS:RGD.::GO:0019343; P:cysteine biosynthetic process via cystathionine; IEA:InterPro.::GO:0070814; P:hydrogen sulfide biosynthetic process; IDA:UniProtKB.::GO:0043066; P:negative regulation of apoptotic process; IDA:UniProtKB.::GO:0019346; P:transsulfuration; IDA:RGD.
6P35520    551   CBS_HUMAN Cystathionine beta-synthase OS=Homo...4354e-126     386     47     65GO:0005829; C:cytosol; IDA:UniProtKB.::GO:0005730; C:nucleolus; IDA:HPA.
GO:0004122; F:cystathionine beta-synthase activity; IDA:UniProtKB.::GO:0020037; F:heme binding; IDA:UniProtKB.::GO:0072341; F:modified amino acid binding; IDA:UniProtKB.::GO:0042803; F:protein homodimerization activity; IDA:UniProtKB.::GO:0030170; F:pyridoxal phosphate binding; IDA:UniProtKB.::GO:0031625; F:ubiquitin protein ligase binding; IPI:UniProtKB.
GO:0006535; P:cysteine biosynthetic process from serine; IEA:InterPro.::GO:0019343; P:cysteine biosynthetic process via cystathionine; IEA:InterPro.::GO:0043418; P:homocysteine catabolic process; IDA:UniProtKB.::GO:0070814; P:hydrogen sulfide biosynthetic process; IDA:UniProtKB.::GO:0019448; P:L-cysteine catabolic process; IDA:UniProtKB.::GO:0006565; P:L-serine catabolic process; IDA:UniProtKB.::GO:0019346; P:transsulfuration; TAS:Reactome.
7Q9N0V7    551   CBS_RABIT Cystathionine beta-synthase OS=Oryc...4349e-122     375     47     66GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0004122; F:cystathionine beta-synthase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
GO:0006535; P:cysteine biosynthetic process from serine; IEA:InterPro.::GO:0019343; P:cysteine biosynthetic process via cystathionine; IEA:InterPro.::GO:0070814; P:hydrogen sulfide biosynthetic process; ISS:UniProtKB.
8Q7D8W0    464   Y1077_MYCTU Putative cystathionine beta-synth...5057e-67     229     34     50GO:0005737; C:cytoplasm; IEA:InterPro.::GO:0005576; C:extracellular region; IDA:MTBBASE.::GO:0005886; C:plasma membrane; IDA:MTBBASE.
GO:0004122; F:cystathionine beta-synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
GO:0019343; P:cysteine biosynthetic process via cystathionine; IEA:InterPro.
9P56067    306   CYSM_HELPY Cysteine synthase OS=pylori). GN=c...3125e-60     206     38     58
GO:0004124; F:cysteine synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
GO:0006535; P:cysteine biosynthetic process from serine; IEA:InterPro.
10Q8CMT6    310   CYSK_STAES Cysteine synthase OS=Staphylococcu...3135e-58     201     39     58
GO:0004124; F:cysteine synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
GO:0006535; P:cysteine biosynthetic process from serine; IEA:InterPro.
11Q5HRP1    310   CYSK_STAEQ Cysteine synthase OS=Staphylococcu...3135e-58     201     39     58
GO:0004124; F:cysteine synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
GO:0006535; P:cysteine biosynthetic process from serine; IEA:InterPro.
12P63872    310   CYSK_STAAW Cysteine synthase OS=Staphylococcu...3146e-58     200     38     59
GO:0004124; F:cysteine synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
GO:0006535; P:cysteine biosynthetic process from serine; IEA:InterPro.
13Q6GBX5    310   CYSK_STAAS Cysteine synthase OS=Staphylococcu...3146e-58     200     38     59
GO:0004124; F:cysteine synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
GO:0006535; P:cysteine biosynthetic process from serine; IEA:InterPro.
14Q6GJF8    310   CYSK_STAAR Cysteine synthase OS=Staphylococcu...3146e-58     200     38     59
GO:0004124; F:cysteine synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
GO:0006535; P:cysteine biosynthetic process from serine; IEA:InterPro.
15P63871    310   CYSK_STAAN Cysteine synthase OS=Staphylococcu...3146e-58     200     38     59
GO:0004124; F:cysteine synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
GO:0006535; P:cysteine biosynthetic process from serine; IEA:InterPro.
16P63870    310   CYSK_STAAM Cysteine synthase OS=Staphylococcu...3146e-58     200     38     59
GO:0004124; F:cysteine synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
GO:0006535; P:cysteine biosynthetic process from serine; IEA:InterPro.
17Q5HIG2    310   CYSK_STAAC Cysteine synthase OS=Staphylococcu...3146e-58     200     38     59
GO:0004124; F:cysteine synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
GO:0006535; P:cysteine biosynthetic process from serine; IEA:InterPro.
18O05393    307   MCCA_BACSU O-acetylserine dependent cystathio...3155e-57     197     38     57
GO:0016829; F:lyase activity; IEA:UniProtKB-KW.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
GO:0006535; P:cysteine biosynthetic process from serine; IEA:InterPro.
19Q5XAQ3    313   CYSK_STRP6 Cysteine synthase OS=Streptococcus...3202e-54     191     39     57
GO:0004124; F:cysteine synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
GO:0006535; P:cysteine biosynthetic process from serine; IEA:InterPro.
20Q9ZMW6    305   CYSM_HELPJ Cysteine synthase OS=Helicobacter ...3122e-53     188     39     59
GO:0004124; F:cysteine synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
GO:0006535; P:cysteine biosynthetic process from serine; IEA:InterPro.
21Q00834    325   CYSK_SPIOL Cysteine synthase OS=Spinacia oler...3453e-53     188     38     54GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004124; F:cysteine synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
GO:0006535; P:cysteine biosynthetic process from serine; IEA:InterPro.
22P47998    322   CYSK1_ARATH Cysteine synthase OS=Arabidopsis ...3375e-53     187     38     52GO:0048046; C:apoplast; IDA:TAIR.::GO:0009570; C:chloroplast stroma; IDA:TAIR.::GO:0005829; C:cytosol; IDA:TAIR.::GO:0005634; C:nucleus; IDA:TAIR.::GO:0005777; C:peroxisome; IDA:TAIR.::GO:0005886; C:plasma membrane; IDA:TAIR.::GO:0005774; C:vacuolar membrane; IDA:TAIR.
GO:0004124; F:cysteine synthase activity; IDA:TAIR.::GO:0005515; F:protein binding; IPI:TAIR.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
GO:0007568; P:aging; IMP:TAIR.::GO:0006535; P:cysteine biosynthetic process from serine; TAS:TAIR.::GO:0046686; P:response to cadmium ion; IDA:TAIR.
23Q43317    325   CYSK_CITLA Cysteine synthase OS=Citrullus lan...3141e-52     186     41     59GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0047458; F:beta-pyrazolylalanine synthase activity; IEA:EC.::GO:0004124; F:cysteine synthase activity; IEA:EC.::GO:0050461; F:L-mimosine synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
GO:0006535; P:cysteine biosynthetic process from serine; IEA:InterPro.
24P38076    325   CYSK_WHEAT Cysteine synthase OS=Triticum aest...3272e-52     186     38     53GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004124; F:cysteine synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
GO:0006535; P:cysteine biosynthetic process from serine; IEA:InterPro.
25Q9XEA8    325   CYSK2_ORYSJ Cysteine synthase OS=Oryza sativa...3292e-52     186     41     57GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004124; F:cysteine synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
GO:0006535; P:cysteine biosynthetic process from serine; IEA:InterPro.
26O34476    311   CYSM_BACSU Probable cysteine synthase OS=Baci...3222e-51     183     39     58
GO:0004124; F:cysteine synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
GO:0006535; P:cysteine biosynthetic process from serine; IEA:InterPro.
27Q9XEA6    321   CYSK1_ORYSJ Cysteine synthase OS=Oryza sativa...3272e-50     181     37     53
GO:0004124; F:cysteine synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
GO:0006535; P:cysteine biosynthetic process from serine; IEA:InterPro.
28O23735    324   CYSK2_BRAJU Cysteine synthase OS=Brassica jun...3382e-50     181     37     51GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004124; F:cysteine synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
GO:0006535; P:cysteine biosynthetic process from serine; IEA:InterPro.
29Q43725    430   CYSKM_ARATH Cysteine synthase, mitochondrial ...3182e-50     183     40     58GO:0009570; C:chloroplast stroma; IDA:TAIR.::GO:0005739; C:mitochondrion; IDA:TAIR.
GO:0005524; F:ATP binding; IDA:TAIR.::GO:0004124; F:cysteine synthase activity; IDA:TAIR.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016740; F:transferase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IDA:TAIR.
GO:0006535; P:cysteine biosynthetic process from serine; IEA:InterPro.::GO:0048868; P:pollen tube development; IMP:TAIR.
30O23733    322   CYSK1_BRAJU Cysteine synthase OS=Brassica jun...3243e-50     180     40     56GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004124; F:cysteine synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
GO:0006535; P:cysteine biosynthetic process from serine; IEA:InterPro.
31P73410    312   CYSK_SYNY3 Cysteine synthase OS=Synechocystis...3147e-50     179     39     57
GO:0004124; F:cysteine synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
GO:0006535; P:cysteine biosynthetic process from serine; IEA:InterPro.
records
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