UniProt_SwissProt BLAST: Single locus

Species:

Saccharomyces cerevisiae S288C

Locus:

YGR145W

Length:

707

Number of sequences:

5887

Description:

YGR145W ENP2 SGDID:S000003377, Chr VII from 781767-783890, Genome Release 64-1-1, Verified ORF, "Essential nucleolar protein, required for biogenesis of the small ribosomal subunit; contains WD repeats, interacts with Mpp10p and Bfr2p, and has homology to Spb1p"

rec.	Subject	Hit Length	Description	Align.Len	E value	Bit score	% ident.	% pos.	GO associations
1	P48234	707	NOL10_YEAST Ribosome biogenesis protein ENP2 ...	707	0	1461	100	100	GO:0030686; C:90S preribosome; IDA:SGD.::GO:0005730; C:nucleolus; IDA:SGD.
									GO:0042274; P:ribosomal small subunit biogenesis; IMP:SGD.::GO:0006364; P:rRNA processing; IPI:SGD.
2	O74879	634	NOL10_SCHPO Ribosome biogenesis protein enp2 ...	614	0	580	49	67	GO:0030686; C:90S preribosome; ISS:PomBase.::GO:0005829; C:cytosol; IDA:PomBase.::GO:0005730; C:nucleolus; ISS:PomBase.
									GO:0042274; P:ribosomal small subunit biogenesis; ISS:PomBase.::GO:0006364; P:rRNA processing; ISS:PomBase.
3	Q9BSC4	688	NOL10_HUMAN Nucleolar protein 10 OS=Homo sapi...	539	1e-157	479	46	65	GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
4	Q66H99	688	NOL10_RAT Nucleolar protein 10 OS=Rattus norv...	539	2e-157	478	46	64	GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
5	Q5RJG1	687	NOL10_MOUSE Nucleolar protein 10 OS=Mus muscu...	539	5e-156	474	46	64	GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
6	Q802W4	722	NOL10_DANRE Nucleolar protein 10 OS=Danio rer...	556	5e-155	473	44	64	GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
7	Q7T0Q5	689	NOL10_XENLA Nucleolar protein 10 OS=Xenopus l...	525	4e-153	467	45	65	GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
8	Q6NVM6	686	NOL10_XENTR Nucleolar protein 10 OS=Xenopus t...	522	2e-149	457	45	65	GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
9	Q9WVA3	326	BUB3_MOUSE Mitotic checkpoint protein BUB3 OS...	79	0.028	40.8	27	48	GO:0000777; C:condensed chromosome kinetochore; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007126; P:meiosis; IEA:UniProtKB-KW.::GO:0000070; P:mitotic sister chromatid segregation; IMP:MGI.::GO:0051983; P:regulation of chromosome segregation; IDA:UniProtKB.::GO:0071173; P:spindle assembly checkpoint; IDA:UniProtKB.
10	Q1JQB2	326	BUB3_BOVIN Mitotic checkpoint protein BUB3 OS...	79	0.028	40.8	27	48	GO:0000777; C:condensed chromosome kinetochore; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007126; P:meiosis; IEA:UniProtKB-KW.::GO:0051983; P:regulation of chromosome segregation; ISS:UniProtKB.::GO:0071173; P:spindle assembly checkpoint; ISS:UniProtKB.
11	Q5RB58	328	BUB3_PONAB Mitotic checkpoint protein BUB3 OS...	79	0.028	40.8	27	48	GO:0000777; C:condensed chromosome kinetochore; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007059; P:chromosome segregation; IEA:UniProtKB-KW.::GO:0007126; P:meiosis; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0051983; P:regulation of chromosome segregation; ISS:UniProtKB.::GO:0071173; P:spindle assembly checkpoint; ISS:UniProtKB.
12	O43684	328	BUB3_HUMAN Mitotic checkpoint protein BUB3 OS...	79	0.03	40.8	27	48	GO:0000777; C:condensed chromosome kinetochore; IEA:UniProtKB-SubCell.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0005634; C:nucleus; IDA:HPA.
									GO:0005515; F:protein binding; IPI:UniProtKB.
									GO:0031145; P:anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; TAS:Reactome.::GO:0008608; P:attachment of spindle microtubules to kinetochore; IDA:UniProtKB.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007126; P:meiosis; IEA:UniProtKB-KW.::GO:0007094; P:mitotic cell cycle spindle assembly checkpoint; TAS:Reactome.::GO:0000236; P:mitotic prometaphase; TAS:Reactome.::GO:0051436; P:negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.
13	Q2GXT0	484	YTM1_CHAGB Ribosome biogenesis protein YTM1 O...	134	0.096	39.7	25	43	GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.::GO:0005654; C:nucleoplasm; IEA:UniProtKB-SubCell.
									GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
14	Q9UTN4	509	PFS2_SCHPO Polyadenylation factor subunit 2 O...	112	0.099	39.7	29	49	GO:0005829; C:cytosol; IDA:PomBase.::GO:0005847; C:mRNA cleavage and polyadenylation specificity factor complex; IDA:PomBase.
									GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0000070; P:mitotic sister chromatid segregation; IMP:PomBase.::GO:0006379; P:mRNA cleavage; ISS:PomBase.::GO:0006378; P:mRNA polyadenylation; ISS:PomBase.::GO:2000045; P:regulation of G1/S transition of mitotic cell cycle; IMP:PomBase.
15	Q9Z1Z2	350	STRAP_MOUSE Serine-threonine kinase receptor-...	111	0.16	38.5	24	44	GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW.
									GO:0005102; F:receptor binding; IDA:MGI.
									GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:MGI.::GO:0030512; P:negative regulation of transforming growth factor beta receptor signaling pathway; IDA:MGI.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
16	Q5XJS5	323	THOC6_DANRE THO complex subunit 6 homolog OS=...	131	0.19	38.1	24	45
									GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
									GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0051028; P:mRNA transport; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
17	Q5ZL33	350	STRAP_CHICK Serine-threonine kinase receptor-...	90	0.19	38.5	26	53	GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW.
									GO:0005102; F:receptor binding; ISS:AgBase.
									GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; ISS:AgBase.::GO:0030512; P:negative regulation of transforming growth factor beta receptor signaling pathway; ISS:AgBase.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
18	Q5E959	350	STRAP_BOVIN Serine-threonine kinase receptor-...	111	0.24	38.1	24	43	GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW.
									GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
19	Q6FT96	711	MDV1_CANGA Mitochondrial division protein 1 O...	127	0.26	38.1	26	42	GO:0005741; C:mitochondrial outer membrane; IEA:UniProtKB-SubCell.
20	Q5XIG8	350	STRAP_RAT Serine-threonine kinase receptor-as...	111	0.26	37.7	24	43	GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW.
									GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
21	Q5ZMV7	313	WDR82_CHICK WD repeat-containing protein 82 O...	95	0.28	37.7	26	49	GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
22	P49178	380	GBB_MAIZE Guanine nucleotide-binding protein ...	99	0.28	37.7	29	44
									GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW.
23	Q6BVZ3	504	PFS2_DEBHA Polyadenylation factor subunit 2 O...	68	0.29	38.1	34	54	GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007059; P:chromosome segregation; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
24	Q9BVA0	655	KTNB1_HUMAN Katanin p80 WD40-containing subun...	164	0.29	38.1	24	40	GO:0008352; C:katanin complex; TAS:UniProtKB.::GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IDA:HPA.::GO:0000922; C:spindle pole; IEA:UniProtKB-SubCell.
									GO:0008017; F:microtubule binding; NAS:UniProtKB.::GO:0046982; F:protein heterodimerization activity; IPI:UniProtKB.
									GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0007026; P:negative regulation of microtubule depolymerization; IMP:UniProtKB.::GO:0031117; P:positive regulation of microtubule depolymerization; IMP:UniProtKB.::GO:0006605; P:protein targeting; NAS:UniProtKB.
25	P26309	610	CDC20_YEAST APC/C activator protein CDC20 OS=...	99	0.29	38.1	25	49	GO:0005680; C:anaphase-promoting complex; IPI:SGD.::GO:0033597; C:mitotic checkpoint complex; IDA:SGD.
									GO:0010997; F:anaphase-promoting complex binding; IDA:SGD.::GO:0097027; F:ubiquitin-protein ligase activator activity; IDA:SGD.
									GO:0051487; P:activation of anaphase-promoting complex activity involved in meiotic cell cycle; IMP:SGD.::GO:0007092; P:activation of mitotic anaphase-promoting complex activity; IMP:SGD.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0008054; P:cyclin catabolic process; IMP:SGD.::GO:0007133; P:meiotic anaphase I; IMP:SGD.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0031577; P:spindle checkpoint; IPI:SGD.
26	Q9Y3F4	350	STRAP_HUMAN Serine-threonine kinase receptor-...	111	0.32	37.7	24	43	GO:0030054; C:cell junction; IDA:HPA.::GO:0005739; C:mitochondrion; IDA:HPA.::GO:0005886; C:plasma membrane; IDA:HPA.::GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW.
									GO:0005515; F:protein binding; IPI:IntAct.
									GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
27	H9L451	392	BAMB_SALTY Outer membrane protein assembly fa...	116	0.53	37	28	46
28	O22785	525	PR19B_ARATH Pre-mRNA-processing factor 19 hom...	192	1.3	35.8	22	44	GO:0005618; C:cell wall; IDA:TAIR.::GO:0009507; C:chloroplast; IDA:TAIR.::GO:0080008; C:CUL4 RING ubiquitin ligase complex; ISS:TAIR.::GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW.
									GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0004842; F:ubiquitin-protein ligase activity; IEA:InterPro.
									GO:0042742; P:defense response to bacterium; IGI:TAIR.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0045087; P:innate immune response; IEA:UniProtKB-KW.::GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
29	Q8YRI1	1526	YY46_NOSS1 Uncharacterized WD repeat-containi...	163	8.5	33.5	21	44
30	P49695	742	PKWA_THECU Probable serine/threonine-protein ...	117	0.65	37	21	45
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
31	Q8BFQ4	313	WDR82_MOUSE WD repeat-containing protein 82 O...	95	0.7	36.6	25	49	GO:0000785; C:chromatin; ISS:UniProtKB.::GO:0072357; C:PTW/PP1 phosphatase complex; ISS:UniProtKB.

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