rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
421 | A6NI72 | 391 | NCF1B_HUMAN Putative neutrophil cytosol facto... | 54 | 2.6 | 32.7 | 28 | 59 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0035091; F:phosphatidylinositol binding; IEA:InterPro. | | | | | | | | | | GO:0007154; P:cell communication; IEA:InterPro. | 422 | Q96DR7 | 871 | ARHGQ_HUMAN Rho guanine nucleotide exchange f... | 66 | 0.12 | 37 | 29 | 52 | GO:0005622; C:intracellular; IEA:InterPro.::GO:0001726; C:ruffle; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro. | | | | | | | | | | GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro. | 423 | P42687 | 497 | SPK1_DUGTI Tyrosine-protein kinase SPK-1 OS=D... | 67 | 0.13 | 37 | 34 | 55 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC. | | | | | | | | | | | 424 | Q2HDI2 | 1214 | MYO1_CHAGB Myosin-1 OS=6347 / NRRL 1970) (Soi... | 50 | 0.14 | 37 | 32 | 60 | GO:0030479; C:actin cortical patch; IEA:UniProtKB-SubCell.::GO:0016459; C:myosin complex; IEA:UniProtKB-KW. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003774; F:motor activity; IEA:InterPro. | | | | | | | | | | | 425 | Q64355 | 560 | EFS_MOUSE Embryonal Fyn-associated substrate ... | 118 | 0.14 | 37 | 30 | 44 | | | | | | | | | | | GO:0017124; F:SH3 domain binding; IDA:MGI. | | | | | | | | | | GO:0007155; P:cell adhesion; IEA:UniProtKB-KW. | 426 | Q8C0D4 | 838 | RHG12_MOUSE Rho GTPase-activating protein 12 ... | 75 | 0.15 | 37 | 28 | 53 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro. | | | | | | | | | | GO:0007165; P:signal transduction; IEA:InterPro. | 427 | Q6CP77 | 357 | SHO1_KLULA High osmolarity signaling protein ... | 53 | 0.16 | 36.6 | 40 | 62 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006950; P:response to stress; IEA:UniProtKB-KW. | 428 | O43586 | 416 | PPIP1_HUMAN Proline-serine-threonine phosphat... | 49 | 0.16 | 36.6 | 33 | 57 | GO:0032154; C:cleavage furrow; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0030027; C:lamellipodium; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016491; F:oxidoreductase activity; IEA:InterPro. | | | | | | | | | | GO:0007155; P:cell adhesion; TAS:ProtInc.::GO:0045087; P:innate immune response; TAS:Reactome.::GO:0035872; P:nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway; TAS:Reactome. | 429 | B5VMS9 | 1265 | SDC25_YEAS6 Guanine nucleotide exchange facto... | 66 | 0.16 | 37 | 35 | 47 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0051056; P:regulation of small GTPase mediated signal transduction; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. | 430 | B3LTF3 | 1252 | SDC25_YEAS1 Guanine nucleotide exchange facto... | 66 | 0.16 | 37 | 35 | 47 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0051056; P:regulation of small GTPase mediated signal transduction; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. | 431 | Q5FVW6 | 328 | SKAP2_XENTR Src kinase-associated phosphoprot... | 69 | 0.16 | 36.2 | 28 | 43 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005543; F:phospholipid binding; IEA:InterPro. | | | | | | | | | | GO:0042113; P:B cell activation; IEA:UniProtKB-KW. | 432 | Q5U4T3 | 771 | RHG26_XENLA Rho GTPase-activating protein 26 ... | 51 | 0.17 | 36.6 | 37 | 51 | GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008093; F:cytoskeletal adaptor activity; IEA:InterPro.::GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0017124; F:SH3 domain binding; IEA:InterPro. | | | | | | | | | | GO:0046847; P:filopodium assembly; IEA:InterPro.::GO:0007165; P:signal transduction; IEA:InterPro. | 433 | Q1LYG0 | 1119 | SPD2A_DANRE SH3 and PX domain-containing prot... | 53 | 0.17 | 36.6 | 32 | 60 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0042995; C:cell projection; IEA:UniProtKB-KW.::GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0002102; C:podosome; ISS:UniProtKB. | | | | | | | | | | GO:0035091; F:phosphatidylinositol binding; IEA:InterPro. | | | | | | | | | | GO:0007154; P:cell communication; IEA:InterPro.::GO:0006801; P:superoxide metabolic process; ISS:UniProtKB. | 434 | O43281 | 561 | EFS_HUMAN Embryonal Fyn-associated substrate ... | 61 | 0.18 | 36.6 | 33 | 51 | GO:0005737; C:cytoplasm; TAS:ProtInc. | | | | | | | | | | GO:0017124; F:SH3 domain binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.::GO:0035556; P:intracellular signal transduction; TAS:ProtInc. | 435 | C8ZCV7 | 1252 | SDC25_YEAS8 Guanine nucleotide exchange facto... | 66 | 0.18 | 36.6 | 35 | 47 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0051056; P:regulation of small GTPase mediated signal transduction; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. | 436 | Q9QX74 | 1474 | SHAN2_RAT SH3 and multiple ankyrin repeat dom... | 49 | 0.19 | 36.6 | 33 | 57 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0060170; C:cilium membrane; IDA:BHF-UCL.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0030426; C:growth cone; IDA:RGD.::GO:0043025; C:neuronal cell body; IDA:RGD.::GO:0014069; C:postsynaptic density; IDA:RGD.::GO:0045211; C:postsynaptic membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0035255; F:ionotropic glutamate receptor binding; ISS:BHF-UCL.::GO:0008022; F:protein C-terminus binding; IPI:RGD.::GO:0017124; F:SH3 domain binding; IPI:RGD. | | | | | | | | | | GO:0007420; P:brain development; IEP:RGD. | 437 | Q80U22 | 1514 | RUSC2_MOUSE Iporin OS=Mus musculus (Mouse). G... | 50 | 0.2 | 36.6 | 36 | 44 | GO:0005829; C:cytosol; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | | 438 | B9M1G0 | 908 | IF2_GEOSF Translation initiation factor IF-2 ... | 104 | 0.21 | 36.6 | 31 | 39 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.::GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW. | | | | | | | | | | | 439 | Q07533 | 885 | CYK3_YEAST Cytokinesis protein 3 OS=Saccharom... | 53 | 0.22 | 36.2 | 40 | 55 | GO:0000142; C:cellular bud neck contractile ring; IDA:SGD. | | | | | | | | | | | | | | | | | | | | GO:0071937; P:barrier septum assembly involved in cell cycle cytokinesis; IPI:SGD. | 440 | O77506 | 263 | LASP1_RABIT LIM and SH3 domain protein 1 OS=O... | 51 | 0.22 | 35.8 | 31 | 57 | GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006811; P:ion transport; IEA:UniProtKB-KW. | 441 | Q9US59 | 140 | SKB5_SCHPO Shk1 kinase-binding protein 5 OS=S... | 51 | 0.22 | 35 | 33 | 53 | GO:0005783; C:endoplasmic reticulum; IDA:PomBase. | | | | | | | | | | GO:0019901; F:protein kinase binding; IDA:UniProtKB. | | | | | | | | | | | 442 | A7A0P0 | 1252 | SDC25_YEAS7 Guanine nucleotide exchange facto... | 66 | 0.24 | 36.2 | 35 | 47 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0051056; P:regulation of small GTPase mediated signal transduction; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. | 443 | A0AUJ5 | 3491 | POLG_BVY3 Genome polyprotein OS=(BVY). GN= ... | 52 | 0.24 | 36.2 | 37 | 52 | GO:0019028; C:viral capsid; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0004197; F:cysteine-type endopeptidase activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0016706; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors; IEA:InterPro.::GO:0016702; F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen; IEA:UniProtKB-KW.::GO:0003723; F:RNA binding; IEA:InterPro.::GO:0003968; F:RNA-directed RNA polymerase activity; IEA:UniProtKB-KW.::GO:0005198; F:structural molecule activity; IEA:InterPro. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW.::GO:0018144; P:RNA-protein covalent cross-linking; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:InterPro.::GO:0019079; P:viral genome replication; IEA:InterPro. | 444 | Q80Z38 | 1476 | SHAN2_MOUSE SH3 and multiple ankyrin repeat d... | 49 | 0.24 | 36.2 | 33 | 57 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0030426; C:growth cone; IEA:UniProtKB-SubCell.::GO:0001917; C:photoreceptor inner segment; IDA:BHF-UCL.::GO:0001750; C:photoreceptor outer segment; IDA:BHF-UCL.::GO:0005886; C:plasma membrane; IDA:BHF-UCL.::GO:0014069; C:postsynaptic density; IEA:UniProtKB-SubCell.::GO:0045211; C:postsynaptic membrane; IEA:UniProtKB-KW.::GO:0019717; C:synaptosome; IDA:BHF-UCL. | | | | | | | | | | GO:0035255; F:ionotropic glutamate receptor binding; IPI:BHF-UCL.::GO:0017124; F:SH3 domain binding; IEA:UniProtKB-KW. | | | | | | | | | | | 445 | Q5ZJ81 | 403 | SHLB2_CHICK Endophilin-B2 OS=Gallus gallus (C... | 51 | 0.26 | 35.8 | 35 | 53 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008093; F:cytoskeletal adaptor activity; IEA:InterPro.::GO:0017124; F:SH3 domain binding; IEA:InterPro. | | | | | | | | | | GO:0046847; P:filopodium assembly; IEA:InterPro.::GO:0007165; P:signal transduction; IEA:InterPro. | 446 | Q8VCM2 | 349 | NOXO1_MOUSE NADPH oxidase organizer 1 OS=Mus ... | 46 | 0.26 | 35.8 | 28 | 57 | | | | | | | | | | | GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.::GO:0016176; F:superoxide-generating NADPH oxidase activator activity; IDA:MGI. | | | | | | | | | | GO:0007154; P:cell communication; IEA:InterPro.::GO:0022617; P:extracellular matrix disassembly; ISS:UniProtKB.::GO:0006801; P:superoxide metabolic process; IDA:MGI. | 447 | Q9UPX8 | 1470 | SHAN2_HUMAN SH3 and multiple ankyrin repeat d... | 49 | 0.26 | 36.2 | 33 | 57 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0060170; C:cilium membrane; ISS:BHF-UCL.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0014069; C:postsynaptic density; IEA:UniProtKB-SubCell.::GO:0045211; C:postsynaptic membrane; IEA:UniProtKB-KW.::GO:0019717; C:synaptosome; ISS:BHF-UCL. | | | | | | | | | | GO:0030160; F:GKAP/Homer scaffold activity; NAS:UniProtKB.::GO:0035255; F:ionotropic glutamate receptor binding; ISS:BHF-UCL.::GO:0017124; F:SH3 domain binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0035556; P:intracellular signal transduction; NAS:UniProtKB. | 448 | Q5XGP7 | 330 | SKA2A_XENLA Src kinase-associated phosphoprot... | 65 | 0.26 | 35.8 | 29 | 45 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005543; F:phospholipid binding; IEA:InterPro. | | | | | | | | | | GO:0042113; P:B cell activation; IEA:UniProtKB-KW. | 449 | Q63767 | 968 | BCAR1_RAT Breast cancer anti-estrogen resista... | 59 | 0.27 | 36.2 | 32 | 51 | GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005925; C:focal adhesion; IDA:UniProtKB.::GO:0005624; C:membrane fraction; ISS:UniProtKB.::GO:0001726; C:ruffle; ISS:UniProtKB. | | | | | | | | | | GO:0017124; F:SH3 domain binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007015; P:actin filament organization; ISS:UniProtKB.::GO:0050853; P:B cell receptor signaling pathway; ISS:UniProtKB.::GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.::GO:0016477; P:cell migration; ISS:UniProtKB.::GO:0007173; P:epidermal growth factor receptor signaling pathway; IDA:UniProtKB.::GO:0007186; P:G-protein coupled receptor signaling pathway; ISS:UniProtKB.::GO:0008286; P:insulin receptor signaling pathway; IDA:UniProtKB.::GO:0007229; P:integrin-mediated signaling pathway; ISS:UniProtKB.::GO:0048011; P:nerve growth factor receptor signaling pathway; IDA:UniProtKB.::GO:0048008; P:platelet-derived growth factor receptor signaling pathway; ISS:UniProtKB.::GO:0030335; P:positive regulation of cell migration; ISS:UniProtKB. | 450 | P16885 | 1265 | PLCG2_HUMAN 1-phosphatidylinositol 4,5-bispho... | 55 | 0.28 | 36.2 | 35 | 58 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005886; C:plasma membrane; IDA:UniProtKB. | | | | | | | | | | GO:0004435; F:phosphatidylinositol phospholipase C activity; IDA:UniProtKB.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0050853; P:B cell receptor signaling pathway; ISS:UniProtKB.::GO:0019722; P:calcium-mediated signaling; NAS:UniProtKB.::GO:0006661; P:phosphatidylinositol biosynthetic process; IDA:UniProtKB.::GO:0009395; P:phospholipid catabolic process; IEA:InterPro.::GO:0030168; P:platelet activation; TAS:Reactome.::GO:0051209; P:release of sequestered calcium ion into cytosol; IDA:UniProtKB.::GO:0050852; P:T cell receptor signaling pathway; ISS:UniProtKB.::GO:0016055; P:Wnt receptor signaling pathway; TAS:UniProtKB. | 451 | Q6DII7 | 345 | SKAP1_XENTR Src kinase-associated phosphoprot... | 58 | 0.29 | 35.8 | 29 | 55 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005543; F:phospholipid binding; IEA:InterPro. | | | | | | | | | | |