Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YGR136W
Length:
241
Number of sequences:
5887
Description:
YGR136W LSB1 SGDID:S000003368, Chr VII from 762428-763153, Genome Release 64-1-1, Verified ORF, "Protein containing an N-terminal SH3 domain; binds Las17p, which is a homolog of human Wiskott-Aldrich Syndrome protein involved in actin patch assembly and actin polymerization"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
391O77774    392   NCF1_BOVIN Neutrophil cytosol factor 1 OS=Bos...560.79     34.3     29     55GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0035091; F:phosphatidylinositol binding; ISS:UniProtKB.
GO:0007154; P:cell communication; IEA:InterPro.::GO:0006612; P:protein targeting to membrane; ISS:UniProtKB.
392Q96RU3    617   FNBP1_HUMAN Formin-binding protein 1 OS=Homo ...600.048     38.5     33     58GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell.::GO:0016023; C:cytoplasmic membrane-bounded vesicle; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005764; C:lysosome; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0042802; F:identical protein binding; IPI:IntAct.::GO:0008289; F:lipid binding; IEA:UniProtKB-KW.
GO:0006897; P:endocytosis; IEA:UniProtKB-KW.
393Q99MZ8    263   LASP1_RAT LIM and SH3 domain protein 1 OS=Rat...650.05     37.7     32     52GO:0030864; C:cortical actin cytoskeleton; IDA:UniProtKB.
GO:0015075; F:ion transmembrane transporter activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
394Q9NR46    395   SHLB2_HUMAN Endophilin-B2 OS=Homo sapiens (Hu...510.05     38.1     37     53GO:0005737; C:cytoplasm; IDA:HGNC.::GO:0005634; C:nucleus; IDA:HPA.
GO:0008093; F:cytoskeletal adaptor activity; IEA:InterPro.::GO:0017124; F:SH3 domain binding; IEA:InterPro.
GO:0046847; P:filopodium assembly; IEA:InterPro.::GO:0007165; P:signal transduction; IEA:InterPro.
395Q7Z6B7    1085   SRGP1_HUMAN SLIT-ROBO Rho GTPase-activating p...840.051     38.5     29     49GO:0005829; C:cytosol; TAS:Reactome.
GO:0007411; P:axon guidance; TAS:Reactome.
396Q8TC17    118   GRAPL_HUMAN GRB2-related adapter protein-like...500.051     36.2     30     56
397Q61792    263   LASP1_MOUSE LIM and SH3 domain protein 1 OS=M...650.051     37.7     32     52GO:0030864; C:cortical actin cytoskeleton; ISS:UniProtKB.::GO:0005925; C:focal adhesion; IDA:MGI.
GO:0051015; F:actin filament binding; IDA:MGI.::GO:0015075; F:ion transmembrane transporter activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
398Q7ZYG4    214   OSTF1_XENLA Osteoclast-stimulating factor 1 O...480.055     37.4     33     56GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
399Q8CIQ7    2027   DOCK3_MOUSE Dedicator of cytokinesis protein ...580.056     38.1     38     53GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:InterPro.::GO:0051020; F:GTPase binding; IEA:InterPro.::GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW.::GO:0017124; F:SH3 domain binding; IEA:UniProtKB-KW.
400Q55CE0    677   MKCF_DICDI Probable serine/threonine-protein ...510.057     38.1     31     59
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
401Q91Z69    1062   SRGP1_MOUSE SLIT-ROBO Rho GTPase-activating p...840.057     38.1     29     49GO:0005622; C:intracellular; IEA:InterPro.
GO:0005100; F:Rho GTPase activator activity; IDA:MGI.::GO:0017048; F:Rho GTPase binding; IDA:MGI.
GO:0016477; P:cell migration; IDA:MGI.::GO:0007266; P:Rho protein signal transduction; IDA:MGI.
402Q3B7M5    260   LASP1_BOVIN LIM and SH3 domain protein 1 OS=B...650.059     37.7     32     52GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006811; P:ion transport; IEA:UniProtKB-KW.
403Q5ZJJ9    202   OSTF1_CHICK Osteoclast-stimulating factor 1 O...480.061     37.4     33     56GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
404Q6P686    214   OSTF1_RAT Osteoclast-stimulating factor 1 OS=...480.064     37.4     33     54GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
405Q5R5W0    261   LASP1_PONAB LIM and SH3 domain protein 1 OS=P...650.066     37.4     32     52GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006811; P:ion transport; IEA:UniProtKB-KW.
406Q62422    215   OSTF1_MOUSE Osteoclast-stimulating factor 1 O...480.067     37.4     33     54GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0017124; F:SH3 domain binding; IDA:MGI.
407Q14847    261   LASP1_HUMAN LIM and SH3 domain protein 1 OS=H...650.068     37.4     32     52GO:0030864; C:cortical actin cytoskeleton; ISS:UniProtKB.
GO:0015075; F:ion transmembrane transporter activity; ISS:UniProtKB.::GO:0005070; F:SH3/SH2 adaptor activity; TAS:ProtInc.::GO:0008270; F:zinc ion binding; IEA:InterPro.
408Q8R3V5    400   SHLB2_MOUSE Endophilin-B2 OS=Mus musculus (Mo...510.075     37.7     37     53GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0008093; F:cytoskeletal adaptor activity; IEA:InterPro.::GO:0017124; F:SH3 domain binding; IEA:InterPro.
GO:0046847; P:filopodium assembly; IEA:InterPro.::GO:0007165; P:signal transduction; IEA:InterPro.
409Q5PPJ9    404   SHLB2_RAT Endophilin-B2 OS=Rattus norvegicus ...510.078     37.4     37     53GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0008093; F:cytoskeletal adaptor activity; IEA:InterPro.::GO:0017124; F:SH3 domain binding; IEA:InterPro.
GO:0046847; P:filopodium assembly; IEA:InterPro.::GO:0007165; P:signal transduction; IEA:InterPro.
410Q08DK5    395   SHLB2_BOVIN Endophilin-B2 OS=Bos taurus (Bovi...510.086     37.4     37     53GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0008093; F:cytoskeletal adaptor activity; IEA:InterPro.::GO:0017124; F:SH3 domain binding; IEA:InterPro.
GO:0046847; P:filopodium assembly; IEA:InterPro.::GO:0007165; P:signal transduction; IEA:InterPro.
411Q8N2Y8    1516   RUSC2_HUMAN Iporin OS=Homo sapiens (Human). G...500.089     37.7     36     46GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.
412Q8TE67    593   ES8L3_HUMAN Epidermal growth factor receptor ...730.094     37.4     30     53GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
413O75044    1071   FNBP2_HUMAN SLIT-ROBO Rho GTPase-activating p...740.1     37.4     28     50GO:0005829; C:cytosol; TAS:Reactome.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
GO:0007411; P:axon guidance; TAS:Reactome.::GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.
414Q62415    1087   ASPP1_MOUSE Apoptosis-stimulating of p53 prot...530.1     37.4     32     53GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0006917; P:induction of apoptosis; ISS:UniProtKB.
415Q91Z67    1071   FNBP2_MOUSE SLIT-ROBO Rho GTPase-activating p...740.1     37.4     28     50GO:0005743; C:mitochondrial inner membrane; IDA:MGI.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
GO:0007165; P:signal transduction; IEA:InterPro.
416Q80TY0    616   FNBP1_MOUSE Formin-binding protein 1 OS=Mus m...600.11     37.4     33     58GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell.::GO:0016023; C:cytoplasmic membrane-bounded vesicle; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005764; C:lysosome; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0008289; F:lipid binding; IEA:UniProtKB-KW.
GO:0006897; P:endocytosis; IEA:UniProtKB-KW.
417Q8R511    616   FNBP1_RAT Formin-binding protein 1 OS=Rattus ...600.11     37     33     58GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell.::GO:0016023; C:cytoplasmic membrane-bounded vesicle; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005764; C:lysosome; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0008289; F:lipid binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0006897; P:endocytosis; IEA:UniProtKB-KW.::GO:0007399; P:nervous system development; IDA:RGD.
418P38822    633   BZZ1_YEAST Protein BZZ1 OS=Saccharomyces cere...520.11     37     37     58GO:0030479; C:actin cortical patch; IDA:SGD.::GO:0043332; C:mating projection tip; IDA:SGD.
GO:0005515; F:protein binding; IPI:IntAct.
GO:0007015; P:actin filament organization; IPI:SGD.::GO:0006897; P:endocytosis; IGI:SGD.::GO:0009651; P:response to salt stress; IGI:SGD.
419Q7TNR9    484   ARHG4_MOUSE Rho guanine nucleotide exchange f...400.12     37     35     65GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0030676; F:Rac guanyl-nucleotide exchange factor activity; ISS:UniProtKB.
GO:0046847; P:filopodium assembly; ISS:UniProtKB.::GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0030032; P:lamellipodium assembly; ISS:UniProtKB.::GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro.
420P14598    390   NCF1_HUMAN Neutrophil cytosol factor 1 OS=Hom...542.5     32.7     28     59GO:0005829; C:cytosol; TAS:ProtInc.::GO:0043020; C:NADPH oxidase complex; TAS:BHF-UCL.::GO:0032010; C:phagolysosome; TAS:Reactome.::GO:0005625; C:soluble fraction; TAS:ProtInc.
GO:0009055; F:electron carrier activity; TAS:UniProtKB.::GO:0005525; F:GTP binding; TAS:ProtInc.::GO:0003924; F:GTPase activity; TAS:ProtInc.::GO:0035091; F:phosphatidylinositol binding; IDA:UniProtKB.::GO:0017124; F:SH3 domain binding; IPI:BHF-UCL.
GO:0002479; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; TAS:Reactome.::GO:0007154; P:cell communication; IEA:InterPro.::GO:0006968; P:cellular defense response; TAS:ProtInc.::GO:0045087; P:innate immune response; TAS:BHF-UCL.::GO:0006612; P:protein targeting to membrane; IDA:UniProtKB.::GO:0042554; P:superoxide anion generation; TAS:BHF-UCL.
421A6NI72    391   NCF1B_HUMAN Putative neutrophil cytosol facto...542.6     32.7     28     59GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.
GO:0007154; P:cell communication; IEA:InterPro.
records
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