Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YGR136W
Length:
241
Number of sequences:
5887
Description:
YGR136W LSB1 SGDID:S000003368, Chr VII from 762428-763153, Genome Release 64-1-1, Verified ORF, "Protein containing an N-terminal SH3 domain; binds Las17p, which is a homolog of human Wiskott-Aldrich Syndrome protein involved in actin patch assembly and actin polymerization"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
31Q96HL8    342   SH3Y1_HUMAN SH3 domain-containing YSC84-like ...520.000000002     60.5     54     65
32Q3UTJ2    1180   SRBS2_MOUSE Sorbin and SH3 domain-containing ...520.0006     44.3     37     56GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.::GO:0030018; C:Z disc; IEA:UniProtKB-SubCell.
GO:0008270; F:zinc ion binding; IEA:InterPro.
33Q5RAQ2    342   SH3Y1_PONAB SH3 domain-containing YSC84-like ...520.000000002     60.5     54     65
34O35413    1196   SRBS2_RAT Sorbin and SH3 domain-containing pr...520.0006     44.3     37     56GO:0043025; C:neuronal cell body; IDA:RGD.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.::GO:0014069; C:postsynaptic density; IDA:RGD.
GO:0008270; F:zinc ion binding; IEA:InterPro.
35P0CR79    660   HSE1_CRYNB Class E vacuolar protein-sorting m...580.000000002     60.8     43     64GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.
GO:0006886; P:intracellular protein transport; IEA:InterPro.
36O94875    1100   SRBS2_HUMAN Sorbin and SH3 domain-containing ...520.0004     45.1     38     56GO:0015629; C:actin cytoskeleton; TAS:ProtInc.::GO:0005622; C:intracellular; IEA:InterPro.::GO:0005634; C:nucleus; NAS:UniProtKB.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.::GO:0030018; C:Z disc; NAS:UniProtKB.
GO:0008093; F:cytoskeletal adaptor activity; TAS:ProtInc.::GO:0005200; F:structural constituent of cytoskeleton; TAS:ProtInc.::GO:0008307; F:structural constituent of muscle; TAS:ProtInc.::GO:0008270; F:zinc ion binding; IEA:InterPro.
37Q13588    217   GRAP_HUMAN GRB2-related adapter protein OS=Ho...500.18     35.8     30     56GO:0005829; C:cytosol; TAS:Reactome.
GO:0005070; F:SH3/SH2 adaptor activity; TAS:ProtInc.
GO:0007267; P:cell-cell signaling; TAS:ProtInc.::GO:0007265; P:Ras protein signal transduction; TAS:ProtInc.
38Q15811    1721   ITSN1_HUMAN Intersectin-1 OS=Homo sapiens (Hu...880.026     39.3     32     51GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005905; C:coated pit; IDA:UniProtKB.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0030027; C:lamellipodium; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IDA:UniProtKB.::GO:0045202; C:synapse; IEA:UniProtKB-KW.::GO:0019717; C:synaptosome; IEA:UniProtKB-SubCell.
GO:0005509; F:calcium ion binding; NAS:UniProtKB.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0070064; F:proline-rich region binding; IPI:UniProtKB.::GO:0032947; F:protein complex scaffold; IDA:UniProtKB.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro.
GO:0006915; P:apoptotic process; TAS:Reactome.::GO:0008624; P:induction of apoptosis by extracellular signals; TAS:Reactome.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.::GO:0048488; P:synaptic vesicle endocytosis; TAS:ProtInc.
39P0CR78    660   HSE1_CRYNJ Class E vacuolar protein-sorting m...580.000000002     60.5     43     64GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.
GO:0006886; P:intracellular protein transport; IEA:InterPro.
40Q6DFH5    335   SH3Y1_XENLA SH3 domain-containing YSC84-like ...500.000000003     60.1     58     64
41B0BNA1    340   SH3Y1_RAT SH3 domain-containing YSC84-like pr...520.000000003     59.7     54     65
42Q5BBL4    581   HSE1_EMENI Class E vacuolar protein-sorting m...570.000000003     60.1     46     61GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.
GO:0006886; P:intracellular protein transport; IEA:InterPro.
43O08641    340   SH3Y1_MOUSE SH3 domain-containing YSC84-like ...520.000000003     59.7     54     65
GO:0005515; F:protein binding; IPI:IntAct.
44Q9CX99    217   GRAP_MOUSE GRB2-related adapter protein OS=Mu...500.18     35.8     30     56
45Q6BNP6    512   HSE1_DEBHA Class E vacuolar protein-sorting m...660.000000005     59.3     44     58GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.
GO:0006886; P:intracellular protein transport; IEA:InterPro.
46Q4WHP5    584   HSE1_ASPFU Class E vacuolar protein-sorting m...580.000000005     59.3     43     62GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.
GO:0006886; P:intracellular protein transport; IEA:InterPro.
47Q0CJU8    597   HSE1_ASPTN Class E vacuolar protein-sorting m...580.000000006     59.3     43     62GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.
GO:0006886; P:intracellular protein transport; IEA:InterPro.
48O75886    525   STAM2_HUMAN Signal transducing adapter molecu...500.000000006     59.3     46     74GO:0005829; C:cytosol; TAS:Reactome.::GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IDA:HPA.
GO:0005515; F:protein binding; IPI:IntAct.
GO:0016044; P:cellular membrane organization; TAS:Reactome.::GO:0016197; P:endosome transport; TAS:Reactome.::GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.::GO:0006886; P:intracellular protein transport; IEA:InterPro.::GO:0042059; P:negative regulation of epidermal growth factor receptor signaling pathway; TAS:Reactome.
49O42287    1270   ITSN1_XENLA Intersectin-1 OS=Xenopus laevis (...860.006     41.2     33     53GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0012505; C:endomembrane system; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-KW.::GO:0045202; C:synapse; IEA:UniProtKB-KW.::GO:0019717; C:synaptosome; IEA:UniProtKB-SubCell.
GO:0005509; F:calcium ion binding; IEA:InterPro.
GO:0006897; P:endocytosis; IEA:UniProtKB-KW.
50Q0U6X7    618   HSE1_PHANO Class E vacuolar protein-sorting m...580.000000007     58.9     45     59GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.
GO:0006886; P:intracellular protein transport; IEA:InterPro.
51A1DFN5    603   HSE1_NEOFI Class E vacuolar protein-sorting m...580.000000007     58.9     43     62GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.
GO:0006886; P:intracellular protein transport; IEA:InterPro.
52A1CEK6    599   HSE1_ASPCL Class E vacuolar protein-sorting m...580.000000007     58.9     43     62GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.
GO:0006886; P:intracellular protein transport; IEA:InterPro.
53A2QW93    611   HSE1_ASPNC Class E vacuolar protein-sorting m...580.000000007     58.9     43     62GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.
GO:0006886; P:intracellular protein transport; IEA:InterPro.
54Q6YKA8    211   DRK_DROSI Protein E(sev)2B OS=Drosophila simu...500.27     35.4     32     60GO:0005886; C:plasma membrane; ISS:UniProtKB.
GO:0005070; F:SH3/SH2 adaptor activity; ISS:UniProtKB.::GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW.
55Q08012    211   DRK_DROME Protein enhancer of sevenless 2B OS...500.27     35.4     32     60GO:0005886; C:plasma membrane; IDA:UniProtKB.
GO:0005118; F:sevenless binding; IPI:FlyBase.::GO:0005070; F:SH3/SH2 adaptor activity; NAS:UniProtKB.::GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW.
GO:0007015; P:actin filament organization; IMP:FlyBase.::GO:0007256; P:activation of JNKK activity; NAS:UniProtKB.::GO:0008595; P:anterior/posterior axis specification, embryo; TAS:FlyBase.::GO:0001700; P:embryonic development via the syncytial blastoderm; IMP:FlyBase.::GO:0007476; P:imaginal disc-derived wing morphogenesis; IMP:FlyBase.::GO:0007175; P:negative regulation of epidermal growth factor-activated receptor activity; IGI:FlyBase.::GO:0008355; P:olfactory learning; IMP:FlyBase.::GO:0045678; P:positive regulation of R7 cell differentiation; IGI:FlyBase.::GO:0007265; P:Ras protein signal transduction; IPI:FlyBase.::GO:0008360; P:regulation of cell shape; IMP:FlyBase.::GO:0045500; P:sevenless signaling pathway; IGI:FlyBase.::GO:0007614; P:short-term memory; IMP:FlyBase.::GO:0008293; P:torso signaling pathway; TAS:FlyBase.
56Q9JLQ0    637   CD2AP_MOUSE CD2-associated protein OS=Mus mus...540.035     38.9     28     59GO:0005829; C:cytosol; TAS:Reactome.::GO:0005886; C:plasma membrane; IDA:MGI.::GO:0001726; C:ruffle; IEA:UniProtKB-SubCell.
GO:0017124; F:SH3 domain binding; IEA:UniProtKB-KW.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.
57Q9WVE9    1217   ITSN1_RAT Intersectin-1 OS=Rattus norvegicus ...500.13     37     38     58GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0012505; C:endomembrane system; IEA:UniProtKB-SubCell.::GO:0030027; C:lamellipodium; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-KW.::GO:0045202; C:synapse; IEA:UniProtKB-KW.::GO:0019717; C:synaptosome; IEA:UniProtKB-SubCell.
GO:0005509; F:calcium ion binding; IEA:InterPro.
GO:0006897; P:endocytosis; IEA:UniProtKB-KW.::GO:0006887; P:exocytosis; TAS:RGD.
58P38753    452   HSE1_YEAST Class E vacuolar protein-sorting m...520.00000001     58.2     46     62GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.::GO:0033565; C:ESCRT-0 complex; IPI:SGD.
GO:0043130; F:ubiquitin binding; IDA:SGD.
GO:0045324; P:late endosome to vacuole transport; IMP:SGD.::GO:0006623; P:protein targeting to vacuole; IMP:SGD.
59Q7S6J4    745   HSE1_NEUCR Class E vacuolar protein-sorting m...610.00000001     58.5     46     56GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.
GO:0006886; P:intracellular protein transport; IEA:InterPro.
60Q9Z0R4    1714   ITSN1_MOUSE Intersectin-1 OS=Mus musculus (Mo...500.15     37     38     58GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0030139; C:endocytic vesicle; IDA:MGI.::GO:0012505; C:endomembrane system; IEA:UniProtKB-SubCell.::GO:0030027; C:lamellipodium; IDA:MGI.::GO:0016020; C:membrane; IEA:UniProtKB-KW.::GO:0045202; C:synapse; IEA:UniProtKB-KW.::GO:0019717; C:synaptosome; IEA:UniProtKB-SubCell.
GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0019209; F:kinase activator activity; IDA:MGI.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro.
GO:0006897; P:endocytosis; IEA:UniProtKB-KW.::GO:0043524; P:negative regulation of neuron apoptotic process; IMP:MGI.::GO:0051897; P:positive regulation of protein kinase B signaling cascade; IDA:MGI.::GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IDA:MGI.
61Q8R1B0    408   STAC2_MOUSE SH3 and cysteine-rich domain-cont...520.00000002     57.8     44     75
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0035556; P:intracellular signal transduction; IEA:InterPro.
records
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