rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
1 | P53281 | 241 | LSB1_YEAST LAS seventeen-binding protein 1 OS... | 241 | 1e-170 | 477 | 100 | 100 | GO:0030479; C:actin cortical patch; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IDA:SGD. | | | | | | | | | | GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | | 2 | Q06449 | 215 | PIN3_YEAST [PSI+] inducibility protein 3 OS=S... | 244 | 2e-63 | 203 | 54 | 65 | GO:0030479; C:actin cortical patch; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IDA:SGD. | | | | | | | | | | GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | GO:0030036; P:actin cytoskeleton organization; IPI:SGD. | 3 | Q5HYK7 | 790 | SH319_HUMAN SH3 domain-containing protein 19 ... | 51 | 0.001 | 43.1 | 33 | 61 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005794; C:Golgi apparatus; IDA:HPA.::GO:0005634; C:nucleus; IDA:HPA.::GO:0005886; C:plasma membrane; IDA:BHF-UCL. | | | | | | | | | | GO:0070064; F:proline-rich region binding; IPI:BHF-UCL. | | | | | | | | | | GO:0016044; P:cellular membrane organization; TAS:Reactome.::GO:0007010; P:cytoskeleton organization; IMP:UniProtKB.::GO:0051044; P:positive regulation of membrane protein ectodomain proteolysis; IMP:BHF-UCL.::GO:0006892; P:post-Golgi vesicle-mediated transport; TAS:Reactome.::GO:0022604; P:regulation of cell morphogenesis; IMP:UniProtKB. | 4 | O74749 | 373 | HSE1_SCHPO Class E vacuolar protein-sorting m... | 69 | 0.0000000000007 | 70.5 | 49 | 59 | GO:0005829; C:cytosol; IDA:PomBase.::GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.::GO:0033565; C:ESCRT-0 complex; IPI:PomBase.::GO:0005794; C:Golgi apparatus; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase. | | | | | | | | | | | | | | | | | | | | GO:0031321; P:ascospore-type prospore assembly; IGI:PomBase.::GO:0033554; P:cellular response to stress; IEP:PomBase.::GO:0006900; P:membrane budding; IC:PomBase.::GO:0043328; P:protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway; IMP:PomBase. | 5 | Q91X43 | 789 | SH319_MOUSE SH3 domain-containing protein 19 ... | 49 | 0.012 | 40.4 | 33 | 61 | | | | | | | | | | | | | | | | | | | | | GO:0007010; P:cytoskeleton organization; ISS:UniProtKB.::GO:0022604; P:regulation of cell morphogenesis; ISS:UniProtKB. | 6 | P29355 | 228 | SEM5_CAEEL Sex muscle abnormal protein 5 OS=C... | 80 | 0.021 | 38.9 | 26 | 48 | | | | | | | | | | | | | | | | | | | | | GO:0016477; P:cell migration; IMP:WormBase.::GO:0008340; P:determination of adult lifespan; IMP:WormBase.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0040035; P:hermaphrodite genitalia development; IMP:WormBase.::GO:0019915; P:lipid storage; IMP:WormBase.::GO:0030539; P:male genitalia development; IMP:WormBase.::GO:0007517; P:muscle organ development; IMP:WormBase.::GO:0040015; P:negative regulation of multicellular organism growth; IMP:WormBase.::GO:0002119; P:nematode larval development; IMP:WormBase.::GO:0040010; P:positive regulation of growth rate; IMP:WormBase.::GO:0006898; P:receptor-mediated endocytosis; IMP:WormBase.::GO:0031344; P:regulation of cell projection organization; IMP:WormBase.::GO:0040028; P:regulation of vulval development; IMP:WormBase.::GO:0032940; P:secretion by cell; IMP:WormBase. | 7 | O43125 | 296 | CSH3_SCHPO Protein csh3 OS=Schizosaccharomyce... | 186 | 0.000000000009 | 66.6 | 33 | 44 | GO:0005737; C:cytoplasm; IDA:PomBase. | | | | | | | | | | | | | | | | | | | | GO:0030036; P:actin cytoskeleton organization; ISS:PomBase. | 8 | Q07883 | 217 | GRB2_CHICK Growth factor receptor-bound prote... | 50 | 0.00004 | 47 | 44 | 64 | GO:0005768; C:endosome; ISS:UniProtKB.::GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | | | | | | | | | | | | 9 | O75791 | 330 | GRAP2_HUMAN GRB2-related adapter protein 2 OS... | 52 | 1 | 33.9 | 29 | 56 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005768; C:endosome; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:UniProtKB. | | | | | | | | | | GO:0005070; F:SH3/SH2 adaptor activity; TAS:ProtInc. | | | | | | | | | | GO:0007267; P:cell-cell signaling; TAS:ProtInc.::GO:0007265; P:Ras protein signal transduction; TAS:ProtInc.::GO:0031295; P:T cell costimulation; TAS:Reactome.::GO:0050852; P:T cell receptor signaling pathway; TAS:Reactome. | 10 | Q60631 | 217 | GRB2_MOUSE Growth factor receptor-bound prote... | 50 | 0.00003 | 47.4 | 44 | 64 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005768; C:endosome; ISS:UniProtKB.::GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; ISS:UniProtKB.::GO:0005886; C:plasma membrane; IDA:MGI.::GO:0012506; C:vesicle membrane; IDA:MGI. | | | | | | | | | | GO:0046875; F:ephrin receptor binding; IPI:UniProtKB.::GO:0019904; F:protein domain specific binding; IPI:MGI.::GO:0019903; F:protein phosphatase binding; IPI:UniProtKB.::GO:0005070; F:SH3/SH2 adaptor activity; IDA:MGI. | | | | | | | | | | GO:0048646; P:anatomical structure formation involved in morphogenesis; IMP:MGI.::GO:0060670; P:branching involved in embryonic placenta morphogenesis; IMP:MGI.::GO:0030154; P:cell differentiation; IMP:MGI.::GO:0030838; P:positive regulation of actin filament polymerization; IGI:MGI.::GO:0007265; P:Ras protein signal transduction; TAS:MGI.::GO:0043408; P:regulation of MAPK cascade; IGI:MGI. | 11 | P62994 | 217 | GRB2_RAT Growth factor receptor-bound protein... | 50 | 0.00003 | 47.4 | 44 | 64 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005768; C:endosome; ISS:UniProtKB.::GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; ISS:UniProtKB.::GO:0043234; C:protein complex; IDA:RGD. | | | | | | | | | | GO:0005154; F:epidermal growth factor receptor binding; ISS:UniProtKB.::GO:0043560; F:insulin receptor substrate binding; IPI:RGD.::GO:0001784; F:phosphotyrosine binding; IPI:RGD.::GO:0019904; F:protein domain specific binding; IPI:RGD. | | | | | | | | | | GO:0007568; P:aging; IPI:RGD.::GO:0051291; P:protein heterooligomerization; IDA:RGD.::GO:0007265; P:Ras protein signal transduction; TAS:RGD. | 12 | Q5R4J7 | 217 | GRB2_PONAB Growth factor receptor-bound prote... | 50 | 0.00003 | 47.4 | 44 | 64 | GO:0005768; C:endosome; ISS:UniProtKB.::GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | | | | | | | | | | | | 13 | P62993 | 217 | GRB2_HUMAN Growth factor receptor-bound prote... | 50 | 0.00003 | 47.4 | 44 | 64 | GO:0005829; C:cytosol; TAS:HGNC.::GO:0005768; C:endosome; IDA:UniProtKB.::GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0070436; C:Grb2-EGFR complex; IDA:BHF-UCL.::GO:0005634; C:nucleus; IDA:UniProtKB. | | | | | | | | | | GO:0046875; F:ephrin receptor binding; IPI:UniProtKB.::GO:0005154; F:epidermal growth factor receptor binding; IPI:UniProtKB.::GO:0043560; F:insulin receptor substrate binding; IPI:UniProtKB.::GO:0005168; F:neurotrophin TRKA receptor binding; IPI:UniProtKB.::GO:0019901; F:protein kinase binding; IPI:BHF-UCL.::GO:0005070; F:SH3/SH2 adaptor activity; TAS:UniProtKB. | | | | | | | | | | GO:0007411; P:axon guidance; TAS:Reactome.::GO:0007267; P:cell-cell signaling; TAS:UniProtKB.::GO:0071479; P:cellular response to ionizing radiation; IMP:BHF-UCL.::GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:UniProtKB.::GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.::GO:0008286; P:insulin receptor signaling pathway; IPI:UniProtKB.::GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW.::GO:0050900; P:leukocyte migration; TAS:Reactome.::GO:0042059; P:negative regulation of epidermal growth factor receptor signaling pathway; TAS:Reactome.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0030168; P:platelet activation; TAS:Reactome.::GO:2000379; P:positive regulation of reactive oxygen species metabolic process; IMP:BHF-UCL.::GO:0007265; P:Ras protein signal transduction; TAS:UniProtKB.::GO:0031623; P:receptor internalization; IMP:BHF-UCL.::GO:0042770; P:signal transduction in response to DNA damage; IMP:BHF-UCL.::GO:0031295; P:T cell costimulation; TAS:Reactome. | 14 | Q6FN49 | 450 | HSE1_CANGA Class E vacuolar protein-sorting m... | 52 | 0.00000000003 | 66.2 | 54 | 67 | GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006886; P:intracellular protein transport; IEA:InterPro. | 15 | P87379 | 229 | GRB2A_XENLA Growth factor receptor-bound prot... | 50 | 0.00003 | 47.4 | 44 | 64 | GO:0005768; C:endosome; ISS:UniProtKB.::GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0005154; F:epidermal growth factor receptor binding; ISS:UniProtKB.::GO:0043560; F:insulin receptor substrate binding; ISS:UniProtKB. | | | | | | | | | | GO:0007143; P:female meiosis; IDA:UniProtKB.::GO:0008286; P:insulin receptor signaling pathway; ISS:UniProtKB.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW. | 16 | O89100 | 322 | GRAP2_MOUSE GRB2-related adaptor protein 2 OS... | 52 | 1.6 | 33.5 | 29 | 56 | GO:0005768; C:endosome; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0005515; F:protein binding; IPI:MGI. | | | | | | | | | | | 17 | Q66II3 | 229 | GRB2_XENTR Growth factor receptor-bound prote... | 50 | 0.00004 | 47 | 44 | 64 | GO:0005768; C:endosome; ISS:UniProtKB.::GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0005154; F:epidermal growth factor receptor binding; ISS:UniProtKB.::GO:0043560; F:insulin receptor substrate binding; ISS:UniProtKB. | | | | | | | | | | GO:0008286; P:insulin receptor signaling pathway; ISS:UniProtKB.::GO:0007126; P:meiosis; IEA:UniProtKB-KW.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW. | 18 | A4RF61 | 718 | HSE1_MAGO7 Class E vacuolar protein-sorting m... | 51 | 0.00000000005 | 65.5 | 55 | 65 | GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006886; P:intracellular protein transport; IEA:InterPro. | 19 | Q6C2N2 | 685 | HSE1_YARLI Class E vacuolar protein-sorting m... | 56 | 0.00000000005 | 65.5 | 50 | 64 | GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006886; P:intracellular protein transport; IEA:InterPro. | 20 | Q6GPJ9 | 229 | GRB2B_XENLA Growth factor receptor-bound prot... | 50 | 0.00003 | 47.4 | 44 | 64 | GO:0005768; C:endosome; ISS:UniProtKB.::GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0005154; F:epidermal growth factor receptor binding; ISS:UniProtKB.::GO:0043560; F:insulin receptor substrate binding; ISS:UniProtKB. | | | | | | | | | | GO:0007143; P:female meiosis; IDA:UniProtKB.::GO:0008286; P:insulin receptor signaling pathway; ISS:UniProtKB.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW. | 21 | Q92783 | 540 | STAM1_HUMAN Signal transducing adapter molecu... | 55 | 0.0000000002 | 63.9 | 44 | 71 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005070; F:SH3/SH2 adaptor activity; TAS:ProtInc. | | | | | | | | | | GO:0016044; P:cellular membrane organization; TAS:Reactome.::GO:0016197; P:endosome transport; TAS:Reactome.::GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.::GO:0006886; P:intracellular protein transport; IEA:InterPro.::GO:0042059; P:negative regulation of epidermal growth factor receptor signaling pathway; TAS:Reactome. | 22 | Q2GT05 | 713 | HSE1_CHAGB Class E vacuolar protein-sorting m... | 166 | 0.051 | 38.1 | 30 | 43 | GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006886; P:intracellular protein transport; IEA:InterPro. | 23 | Q6CVA8 | 508 | HSE1_KLULA Class E vacuolar protein-sorting m... | 71 | 0.0000000002 | 63.5 | 42 | 56 | GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006886; P:intracellular protein transport; IEA:InterPro. | 24 | P32793 | 468 | YSC84_YEAST Protein YSC84 OS=Saccharomyces ce... | 77 | 0.0000000002 | 63.2 | 43 | 64 | GO:0030479; C:actin cortical patch; IDA:SGD. | | | | | | | | | | GO:0051015; F:actin filament binding; IDA:SGD. | | | | | | | | | | GO:0051666; P:actin cortical patch localization; IMP:SGD.::GO:0051017; P:actin filament bundle assembly; IDA:SGD.::GO:0006897; P:endocytosis; IGI:SGD. | 25 | P70297 | 548 | STAM1_MOUSE Signal transducing adapter molecu... | 55 | 0.0000000003 | 63.2 | 42 | 71 | GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005515; F:protein binding; IPI:MGI. | | | | | | | | | | GO:0006886; P:intracellular protein transport; IEA:InterPro. | 26 | A6QLK6 | 217 | GRAP_BOVIN GRB2-related adapter protein OS=Bo... | 50 | 0.16 | 36.2 | 30 | 56 | | | | | | | | | | | | | | | | | | | | | | 27 | O93436 | 468 | STAM2_CHICK Signal transducing adapter molecu... | 82 | 0.0000000006 | 62 | 37 | 60 | GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006886; P:intracellular protein transport; IEA:InterPro. | 28 | Q3SZ01 | 341 | SH3Y1_BOVIN SH3 domain-containing YSC84-like ... | 52 | 0.0000000007 | 61.6 | 54 | 65 | | | | | | | | | | | | | | | | | | | | | | 29 | Q1E878 | 612 | HSE1_COCIM Class E vacuolar protein-sorting m... | 58 | 0.0000000009 | 61.6 | 45 | 62 | GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006886; P:intracellular protein transport; IEA:InterPro. | 30 | Q75DS3 | 443 | HSE1_ASHGO Class E vacuolar protein-sorting m... | 71 | 0.0000000009 | 61.6 | 41 | 58 | GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006886; P:intracellular protein transport; IEA:InterPro. | 31 | Q96HL8 | 342 | SH3Y1_HUMAN SH3 domain-containing YSC84-like ... | 52 | 0.000000002 | 60.5 | 54 | 65 | | | | | | | | | | | | | | | | | | | | | |