Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YGR135W
Length:
258
Number of sequences:
5887
Description:
YGR135W PRE9 SGDID:S000003367, Chr VII from 761392-762168, Genome Release 64-1-1, Verified ORF, "Alpha 3 subunit of the 20S proteasome, the only nonessential 20S subunit; may be replaced by the alpha 4 subunit (Pre6p) under stress conditions to create a more active proteasomal isoform"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
91Q5V2X8    260   PSA1_HALMA Proteasome subunit alpha 1 OS=B-18...2115e-45     157     41     62GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0019773; C:proteasome core complex, alpha-subunit complex; IEA:InterPro.
GO:0004298; F:threonine-type endopeptidase activity; IEA:UniProtKB-KW.
GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
92P24495    234   PSA2_XENLA Proteasome subunit alpha type-2 OS...2396e-45     157     37     57GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0019773; C:proteasome core complex, alpha-subunit complex; IEA:InterPro.
GO:0004298; F:threonine-type endopeptidase activity; IEA:UniProtKB-KW.
GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
93Q0J006    249   PSA7B_ORYSJ Proteasome subunit alpha type-7-B...2036e-45     157     40     64GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0019773; C:proteasome core complex, alpha-subunit complex; IEA:InterPro.
GO:0004298; F:threonine-type endopeptidase activity; IEA:UniProtKB-KW.
GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
94A2Z3I9    249   PSA7B_ORYSI Proteasome subunit alpha type-7-B...2036e-45     157     40     64GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0019773; C:proteasome core complex, alpha-subunit complex; IEA:InterPro.
GO:0004298; F:threonine-type endopeptidase activity; IEA:UniProtKB-KW.
GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
95Q8TAA3    256   PSA7L_HUMAN Proteasome subunit alpha type-7-l...2401e-44     156     36     57GO:0005829; C:cytosol; TAS:Reactome.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0019773; C:proteasome core complex, alpha-subunit complex; IEA:InterPro.
GO:0004298; F:threonine-type endopeptidase activity; IEA:UniProtKB-KW.
GO:0031145; P:anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; TAS:Reactome.::GO:0002479; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; TAS:Reactome.::GO:0006915; P:apoptotic process; TAS:Reactome.::GO:0006977; P:DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest; TAS:Reactome.::GO:0010467; P:gene expression; TAS:Reactome.::GO:0000216; P:M/G1 transition of mitotic cell cycle; TAS:Reactome.::GO:0016071; P:mRNA metabolic process; TAS:Reactome.::GO:0051437; P:positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.::GO:0000209; P:protein polyubiquitination; TAS:Reactome.::GO:0042981; P:regulation of apoptotic process; TAS:Reactome.::GO:0006521; P:regulation of cellular amino acid metabolic process; TAS:Reactome.::GO:0000084; P:S phase of mitotic cell cycle; TAS:Reactome.::GO:0044281; P:small molecule metabolic process; TAS:Reactome.::GO:0016032; P:viral reproduction; TAS:Reactome.
96A4YCU9    240   PSA_METS5 Proteasome subunit alpha OS=Metallo...1952e-44     155     41     63GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0019773; C:proteasome core complex, alpha-subunit complex; IEA:InterPro.
GO:0004298; F:threonine-type endopeptidase activity; IEA:UniProtKB-KW.
GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
97Q55G04    241   PSA5_DICDI Proteasome subunit alpha type-5 OS...2292e-44     155     39     60GO:0005737; C:cytoplasm; IPI:dictyBase.::GO:0005634; C:nucleus; IPI:dictyBase.::GO:0019773; C:proteasome core complex, alpha-subunit complex; IEA:InterPro.
GO:0004298; F:threonine-type endopeptidase activity; IEA:UniProtKB-KW.
GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
98Q9XZJ4    244   PSA6_DROME Proteasome subunit alpha type-6 OS...1944e-44     155     39     61GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0019773; C:proteasome core complex, alpha-subunit complex; IEA:InterPro.
GO:0004298; F:threonine-type endopeptidase activity; IEA:UniProtKB-KW.
GO:0006974; P:response to DNA damage stimulus; IMP:FlyBase.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
99P57697    253   PSA_HALSA Proteasome subunit alpha OS=(Haloba...1945e-44     155     42     62GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0019773; C:proteasome core complex, alpha-subunit complex; IEA:InterPro.
GO:0004298; F:threonine-type endopeptidase activity; IEA:UniProtKB-KW.
GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
100B0R2T2    253   PSA_HALS3 Proteasome subunit alpha OS=Halobac...1945e-44     155     42     62GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0019773; C:proteasome core complex, alpha-subunit complex; IEA:InterPro.
GO:0004298; F:threonine-type endopeptidase activity; IEA:UniProtKB-KW.
GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
101O73672    234   PSA2_CARAU Proteasome subunit alpha type-2 OS...2396e-44     154     36     58GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0019773; C:proteasome core complex, alpha-subunit complex; IEA:InterPro.
GO:0004298; F:threonine-type endopeptidase activity; IEA:UniProtKB-KW.
GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
102P48004    254   PSA7_RAT Proteasome subunit alpha type-7 OS=R...2391e-43     154     36     57GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0019773; C:proteasome core complex, alpha-subunit complex; IEA:InterPro.
GO:0004298; F:threonine-type endopeptidase activity; IEA:UniProtKB-KW.
GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
103Q9NDA2    247   PSA7_TRYBB Proteasome subunit alpha type-7 OS...2002e-43     153     37     60GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0019773; C:proteasome core complex, alpha-subunit complex; IEA:InterPro.
GO:0004298; F:threonine-type endopeptidase activity; IEA:UniProtKB-KW.
GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
104P34064    241   PSA5_RAT Proteasome subunit alpha type-5 OS=R...2392e-43     153     36     59GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0019773; C:proteasome core complex, alpha-subunit complex; IEA:InterPro.
GO:0004298; F:threonine-type endopeptidase activity; IEA:UniProtKB-KW.
GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
105Q975G5    242   PSA_SULTO Proteasome subunit alpha OS=Sulfolo...1953e-43     152     38     61GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0019773; C:proteasome core complex, alpha-subunit complex; IEA:InterPro.
GO:0004298; F:threonine-type endopeptidase activity; IEA:UniProtKB-KW.
GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
106Q9PVY6    248   PSA7A_XENLA Proteasome subunit alpha type-7-A...2333e-43     152     36     58GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0019773; C:proteasome core complex, alpha-subunit complex; IEA:InterPro.
GO:0004298; F:threonine-type endopeptidase activity; IEA:UniProtKB-KW.
GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
107Q9PVQ1    247   PSA7B_XENLA Proteasome subunit alpha type-7-B...2333e-43     152     36     58GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0019773; C:proteasome core complex, alpha-subunit complex; IEA:InterPro.
GO:0004298; F:threonine-type endopeptidase activity; IEA:UniProtKB-KW.
GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
108P23639    250   PSA2_YEAST Proteasome component Y7 OS=Sacchar...2134e-43     152     38     62GO:0005739; C:mitochondrion; IC:SGD.::GO:0042175; C:nuclear outer membrane-endoplasmic reticulum membrane network; IC:SGD.::GO:0005634; C:nucleus; IC:SGD.::GO:0019773; C:proteasome core complex, alpha-subunit complex; IDA:SGD.::GO:0034515; C:proteasome storage granule; IDA:SGD.
GO:0005515; F:protein binding; IPI:IntAct.::GO:0004298; F:threonine-type endopeptidase activity; IEA:UniProtKB-KW.
GO:0043161; P:proteasomal ubiquitin-dependent protein catabolic process; IDA:SGD.::GO:0010499; P:proteasomal ubiquitin-independent protein catabolic process; IDA:SGD.
109Q9XZG5    246   PSA5_TRYBB Proteasome subunit alpha type-5 OS...2267e-43     152     36     58GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0019773; C:proteasome core complex, alpha-subunit complex; IEA:InterPro.
GO:0004298; F:threonine-type endopeptidase activity; IEA:UniProtKB-KW.
GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
110O13268    249   PSA7_CHICK Proteasome subunit alpha type-7 OS...2155e-42     149     37     59GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0019773; C:proteasome core complex, alpha-subunit complex; IEA:InterPro.
GO:0004298; F:threonine-type endopeptidase activity; IEA:UniProtKB-KW.
GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
111P40303    254   PSA7_YEAST Proteasome component PRE6 OS=Sacch...2045e-42     150     35     61GO:0005739; C:mitochondrion; IDA:SGD.::GO:0042175; C:nuclear outer membrane-endoplasmic reticulum membrane network; IDA:SGD.::GO:0005634; C:nucleus; IDA:SGD.::GO:0019773; C:proteasome core complex, alpha-subunit complex; IDA:SGD.::GO:0034515; C:proteasome storage granule; IDA:SGD.
GO:0005515; F:protein binding; IPI:IntAct.::GO:0004298; F:threonine-type endopeptidase activity; IEA:UniProtKB-KW.
GO:0043161; P:proteasomal ubiquitin-dependent protein catabolic process; IDA:SGD.::GO:0010499; P:proteasomal ubiquitin-independent protein catabolic process; IDA:SGD.
112O81149    237   PSA5A_ARATH Proteasome subunit alpha type-5-A...2395e-42     149     34     58GO:0022626; C:cytosolic ribosome; IDA:TAIR.::GO:0005634; C:nucleus; IDA:TAIR.::GO:0005886; C:plasma membrane; IDA:TAIR.::GO:0019773; C:proteasome core complex, alpha-subunit complex; IEA:InterPro.::GO:0005774; C:vacuolar membrane; IDA:TAIR.
GO:0004540; F:ribonuclease activity; IDA:TAIR.::GO:0004298; F:threonine-type endopeptidase activity; IEA:UniProtKB-KW.
GO:0046686; P:response to cadmium ion; IEP:TAIR.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
113Q9UT97    247   PSA5_SCHPO Probable proteasome subunit alpha ...2089e-42     149     39     60GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.::GO:0019773; C:proteasome core complex, alpha-subunit complex; ISS:PomBase.
GO:0004298; F:threonine-type endopeptidase activity; IEA:UniProtKB-KW.
GO:0043161; P:proteasomal ubiquitin-dependent protein catabolic process; NAS:PomBase.::GO:0007346; P:regulation of mitotic cell cycle; IC:PomBase.
114Q95005    253   PSA7_CAEEL Proteasome subunit alpha type-7 OS...2372e-41     148     34     59GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0019773; C:proteasome core complex, alpha-subunit complex; IEA:InterPro.
GO:0005515; F:protein binding; IPI:IntAct.::GO:0004298; F:threonine-type endopeptidase activity; IEA:UniProtKB-KW.
GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0040007; P:growth; IMP:WormBase.::GO:0040011; P:locomotion; IMP:WormBase.::GO:0002119; P:nematode larval development; IMP:WormBase.::GO:0040010; P:positive regulation of growth rate; IMP:WormBase.::GO:0000003; P:reproduction; IMP:WormBase.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
115Q42134    237   PSA5B_ARATH Proteasome subunit alpha type-5-B...2392e-41     147     34     58GO:0022626; C:cytosolic ribosome; IDA:TAIR.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0019773; C:proteasome core complex, alpha-subunit complex; IEA:InterPro.
GO:0004540; F:ribonuclease activity; IDA:TAIR.::GO:0004298; F:threonine-type endopeptidase activity; IEA:UniProtKB-KW.
GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
116P60901    246   PSA6_RAT Proteasome subunit alpha type-6 OS=R...1963e-41     147     37     58GO:0016363; C:nuclear matrix; ISS:BHF-UCL.::GO:0005844; C:polysome; ISS:BHF-UCL.::GO:0019773; C:proteasome core complex, alpha-subunit complex; ISS:BHF-UCL.::GO:0030017; C:sarcomere; IDA:BHF-UCL.
GO:0003723; F:RNA binding; ISS:BHF-UCL.::GO:0004298; F:threonine-type endopeptidase activity; IEA:UniProtKB-KW.
GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; ISS:BHF-UCL.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
117P60900    246   PSA6_HUMAN Proteasome subunit alpha type-6 OS...1963e-41     147     37     58GO:0005829; C:cytosol; TAS:Reactome.::GO:0005739; C:mitochondrion; IDA:HPA.::GO:0016363; C:nuclear matrix; ISS:BHF-UCL.::GO:0005654; C:nucleoplasm; TAS:Reactome.::GO:0005844; C:polysome; IDA:BHF-UCL.::GO:0019773; C:proteasome core complex, alpha-subunit complex; IDA:BHF-UCL.::GO:0030017; C:sarcomere; ISS:BHF-UCL.
GO:0051059; F:NF-kappaB binding; IPI:BHF-UCL.::GO:0035639; F:purine ribonucleoside triphosphate binding; NAS:BHF-UCL.::GO:0003723; F:RNA binding; NAS:UniProtKB.::GO:0004298; F:threonine-type endopeptidase activity; IEA:UniProtKB-KW.
GO:0031145; P:anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; TAS:Reactome.::GO:0002479; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; TAS:Reactome.::GO:0006915; P:apoptotic process; TAS:Reactome.::GO:0006977; P:DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest; TAS:Reactome.::GO:0000082; P:G1/S transition of mitotic cell cycle; TAS:Reactome.::GO:0010467; P:gene expression; TAS:Reactome.::GO:0000216; P:M/G1 transition of mitotic cell cycle; TAS:Reactome.::GO:0016071; P:mRNA metabolic process; TAS:Reactome.::GO:0051436; P:negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.::GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; IMP:BHF-UCL.::GO:0051437; P:positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.::GO:0000209; P:protein polyubiquitination; TAS:Reactome.::GO:0042981; P:regulation of apoptotic process; TAS:Reactome.::GO:0006521; P:regulation of cellular amino acid metabolic process; TAS:Reactome.::GO:0050727; P:regulation of inflammatory response; IC:BHF-UCL.::GO:0000084; P:S phase of mitotic cell cycle; TAS:Reactome.::GO:0044281; P:small molecule metabolic process; TAS:Reactome.::GO:0016032; P:viral reproduction; TAS:Reactome.
118Q2YDE4    246   PSA6_BOVIN Proteasome subunit alpha type-6 OS...1963e-41     147     37     58
GO:0004298; F:threonine-type endopeptidase activity; IEA:UniProtKB-KW.
GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
119Q9QUM9    246   PSA6_MOUSE Proteasome subunit alpha type-6 OS...1964e-41     147     37     58GO:0016363; C:nuclear matrix; IDA:BHF-UCL.::GO:0005844; C:polysome; ISS:BHF-UCL.::GO:0019773; C:proteasome core complex, alpha-subunit complex; ISS:BHF-UCL.::GO:0030017; C:sarcomere; ISS:BHF-UCL.
GO:0003723; F:RNA binding; IDA:BHF-UCL.::GO:0004298; F:threonine-type endopeptidase activity; IEA:UniProtKB-KW.
GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; ISS:BHF-UCL.::GO:0007519; P:skeletal muscle tissue development; NAS:BHF-UCL.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
120Q10329    259   PSA7_SCHPO Probable proteasome subunit alpha ...2025e-41     147     37     62GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.::GO:0019773; C:proteasome core complex, alpha-subunit complex; IDA:PomBase.
GO:0004298; F:threonine-type endopeptidase activity; IEA:UniProtKB-KW.
GO:0043161; P:proteasomal ubiquitin-dependent protein catabolic process; ISS:PomBase.::GO:0007346; P:regulation of mitotic cell cycle; IC:PomBase.
121Q9V2V5    249   PSA2_HALVD Proteasome subunit alpha 2 OS=1474...1847e-41     147     41     61GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0019773; C:proteasome core complex, alpha-subunit complex; IDA:UniProtKB.
GO:0004298; F:threonine-type endopeptidase activity; IEA:UniProtKB-KW.
GO:0010498; P:proteasomal protein catabolic process; IDA:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
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