Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YGR123C
Length:
513
Number of sequences:
5887
Description:
YGR123C PPT1 SGDID:S000003355, Chr VII from 738203-736662, Genome Release 64-1-1, reverse complement, Verified ORF, "Protein serine/threonine phosphatase with similarity to human phosphatase PP5; present in both the nucleus and cytoplasm; expressed during logarithmic growth; computational analyses suggest roles in phosphate metabolism and rRNA processing"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
121Q9CQR6    305   PPP6_MOUSE Serine/threonine-protein phosphata...2663e-55     193     39     58
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
122O00743    305   PPP6_HUMAN Serine/threonine-protein phosphata...2643e-55     193     40     58GO:0005829; C:cytosol; IDA:MGI.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004722; F:protein serine/threonine phosphatase activity; IDA:MGI.
GO:0000082; P:G1/S transition of mitotic cell cycle; TAS:ProtInc.::GO:0006470; P:protein dephosphorylation; IDA:MGI.
123P48463    309   PP2AA_CHICK Serine/threonine-protein phosphat...2664e-55     193     37     55GO:0000775; C:chromosome, centromeric region; IEA:UniProtKB-SubCell.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0000922; C:spindle pole; IEA:UniProtKB-SubCell.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004721; F:phosphoprotein phosphatase activity; IEA:UniProtKB-KW.::GO:0046982; F:protein heterodimerization activity; ISS:UniProtKB.
124Q9M9W3    318   PP19_ARATH Serine/threonine-protein phosphata...2595e-55     193     40     56
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004722; F:protein serine/threonine phosphatase activity; IDA:TAIR.
125P62716    309   PP2AB_RAT Serine/threonine-protein phosphatas...2665e-55     192     38     55GO:0000775; C:chromosome, centromeric region; IEA:UniProtKB-SubCell.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0000922; C:spindle pole; IEA:UniProtKB-SubCell.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0008022; F:protein C-terminus binding; IPI:RGD.::GO:0046982; F:protein heterodimerization activity; ISS:UniProtKB.::GO:0004722; F:protein serine/threonine phosphatase activity; IDA:RGD.
GO:0046580; P:negative regulation of Ras protein signal transduction; IDA:RGD.::GO:0006470; P:protein dephosphorylation; IDA:RGD.
126P62715    309   PP2AB_MOUSE Serine/threonine-protein phosphat...2665e-55     192     38     55GO:0000775; C:chromosome, centromeric region; IEA:UniProtKB-SubCell.::GO:0005737; C:cytoplasm; IDA:MGI.::GO:0005634; C:nucleus; TAS:MGI.::GO:0000159; C:protein phosphatase type 2A complex; IDA:MGI.::GO:0000922; C:spindle pole; IEA:UniProtKB-SubCell.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0043066; P:negative regulation of apoptotic process; IMP:MGI.::GO:0043161; P:proteasomal ubiquitin-dependent protein catabolic process; IMP:MGI.::GO:0010468; P:regulation of gene expression; IMP:MGI.::GO:0046677; P:response to antibiotic; IMP:MGI.::GO:0042542; P:response to hydrogen peroxide; IMP:MGI.
127P62714    309   PP2AB_HUMAN Serine/threonine-protein phosphat...2665e-55     192     38     55GO:0000775; C:chromosome, centromeric region; IEA:UniProtKB-SubCell.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0000159; C:protein phosphatase type 2A complex; TAS:UniProtKB.::GO:0000922; C:spindle pole; IEA:UniProtKB-SubCell.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.::GO:0006470; P:protein dephosphorylation; TAS:UniProtKB.
128P12982    302   PP12_DROME Serine/threonine-protein phosphata...2525e-55     192     39     58GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005700; C:polytene chromosome; IDA:FlyBase.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0017018; F:myosin phosphatase activity; IDA:FlyBase.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0008344; P:adult locomotory behavior; IMP:FlyBase.::GO:0007411; P:axon guidance; IMP:FlyBase.::GO:0030261; P:chromosome condensation; IMP:FlyBase.::GO:0007080; P:mitotic metaphase plate congression; IMP:FlyBase.::GO:0000022; P:mitotic spindle elongation; IMP:FlyBase.::GO:0008355; P:olfactory learning; IMP:FlyBase.::GO:0048477; P:oogenesis; IMP:FlyBase.::GO:0006911; P:phagocytosis, engulfment; IMP:FlyBase.::GO:0006470; P:protein dephosphorylation; IMP:FlyBase.::GO:0051225; P:spindle assembly; IMP:FlyBase.::GO:0008542; P:visual learning; IMP:FlyBase.
129P11493    293   PP2AB_PIG Serine/threonine-protein phosphatas...2665e-55     192     38     55GO:0000775; C:chromosome, centromeric region; IEA:UniProtKB-SubCell.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0000922; C:spindle pole; IEA:UniProtKB-SubCell.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004721; F:phosphoprotein phosphatase activity; IEA:UniProtKB-KW.
130P11611    309   PP2AB_RABIT Serine/threonine-protein phosphat...2665e-55     192     38     55GO:0000775; C:chromosome, centromeric region; IEA:UniProtKB-SubCell.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0000922; C:spindle pole; IEA:UniProtKB-SubCell.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004721; F:phosphoprotein phosphatase activity; IEA:UniProtKB-KW.
131Q0P594    309   PP2AB_BOVIN Serine/threonine-protein phosphat...2666e-55     192     38     55GO:0000775; C:chromosome, centromeric region; IEA:UniProtKB-SubCell.::GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0000922; C:spindle pole; IEA:UniProtKB-SubCell.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004721; F:phosphoprotein phosphatase activity; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.
132A0DJ90    303   PPX2_PARTE Serine/threonine-protein phosphata...2671e-54     191     37     56
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004721; F:phosphoprotein phosphatase activity; IEA:UniProtKB-KW.
133P48457    549   PP2B_EMENI Serine/threonine-protein phosphata...2822e-54     197     39     55
GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004721; F:phosphoprotein phosphatase activity; IEA:UniProtKB-KW.
134P48454    512   PP2BC_HUMAN Serine/threonine-protein phosphat...3062e-54     196     37     55GO:0005829; C:cytosol; TAS:Reactome.
GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004721; F:phosphoprotein phosphatase activity; IEA:UniProtKB-KW.
GO:0008633; P:activation of pro-apoptotic gene products; TAS:Reactome.::GO:0008629; P:induction of apoptosis by intracellular signals; TAS:Reactome.
135P23636    322   PP2A2_SCHPO Major serine/threonine-protein ph...2402e-54     191     42     58GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004721; F:phosphoprotein phosphatase activity; TAS:PomBase.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0045930; P:negative regulation of mitotic cell cycle; IGI:PomBase.::GO:0006470; P:protein dephosphorylation; IMP:PomBase.::GO:0007165; P:signal transduction; NAS:PomBase.
136Q6FM81    309   PP4C_CANGA Serine/threonine-protein phosphata...2683e-54     191     38     56GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004721; F:phosphoprotein phosphatase activity; IEA:UniProtKB-KW.
137P67777    309   PP2AA_RABIT Serine/threonine-protein phosphat...2663e-54     190     37     55GO:0000775; C:chromosome, centromeric region; IEA:UniProtKB-SubCell.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0000922; C:spindle pole; IEA:UniProtKB-SubCell.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004721; F:phosphoprotein phosphatase activity; IEA:UniProtKB-KW.::GO:0046982; F:protein heterodimerization activity; ISS:UniProtKB.
GO:0007126; P:meiosis; IEA:UniProtKB-KW.
138P67776    309   PP2AA_PIG Serine/threonine-protein phosphatas...2663e-54     190     37     55GO:0000775; C:chromosome, centromeric region; IEA:UniProtKB-SubCell.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0000922; C:spindle pole; IEA:UniProtKB-SubCell.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004721; F:phosphoprotein phosphatase activity; IEA:UniProtKB-KW.::GO:0046982; F:protein heterodimerization activity; ISS:UniProtKB.
GO:0007126; P:meiosis; IEA:UniProtKB-KW.
139P67775    309   PP2AA_HUMAN Serine/threonine-protein phosphat...2663e-54     190     37     55GO:0000775; C:chromosome, centromeric region; IEA:UniProtKB-SubCell.::GO:0005829; C:cytosol; TAS:UniProtKB.::GO:0005739; C:mitochondrion; NAS:UniProtKB.::GO:0005634; C:nucleus; NAS:UniProtKB.::GO:0000159; C:protein phosphatase type 2A complex; IDA:UniProtKB.::GO:0005625; C:soluble fraction; NAS:UniProtKB.::GO:0000922; C:spindle pole; IEA:UniProtKB-SubCell.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004721; F:phosphoprotein phosphatase activity; IEA:UniProtKB-KW.
GO:0006672; P:ceramide metabolic process; NAS:UniProtKB.::GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.::GO:0000188; P:inactivation of MAPK activity; NAS:UniProtKB.::GO:0006917; P:induction of apoptosis; TAS:UniProtKB.::GO:0007126; P:meiosis; IEA:UniProtKB-KW.::GO:0030308; P:negative regulation of cell growth; NAS:UniProtKB.::GO:0010719; P:negative regulation of epithelial to mesenchymal transition; IMP:BHF-UCL.::GO:0042518; P:negative regulation of tyrosine phosphorylation of Stat3 protein; NAS:UniProtKB.::GO:0000184; P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; TAS:Reactome.::GO:0071902; P:positive regulation of protein serine/threonine kinase activity; IMP:BHF-UCL.::GO:0006470; P:protein dephosphorylation; TAS:UniProtKB.::GO:0030155; P:regulation of cell adhesion; NAS:UniProtKB.::GO:0006275; P:regulation of DNA replication; NAS:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; NAS:UniProtKB.::GO:0030111; P:regulation of Wnt receptor signaling pathway; NAS:UniProtKB.::GO:0008380; P:RNA splicing; NAS:UniProtKB.::GO:0019932; P:second-messenger-mediated signaling; NAS:UniProtKB.
140P67774    309   PP2AA_BOVIN Serine/threonine-protein phosphat...2663e-54     190     37     55GO:0000775; C:chromosome, centromeric region; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0000922; C:spindle pole; IEA:UniProtKB-SubCell.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004721; F:phosphoprotein phosphatase activity; IEA:UniProtKB-KW.::GO:0046982; F:protein heterodimerization activity; ISS:UniProtKB.
GO:0007126; P:meiosis; IEA:UniProtKB-KW.
141P63331    309   PP2AA_RAT Serine/threonine-protein phosphatas...2664e-54     190     37     55GO:0000775; C:chromosome, centromeric region; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0000922; C:spindle pole; IEA:UniProtKB-SubCell.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0008022; F:protein C-terminus binding; IPI:RGD.::GO:0046982; F:protein heterodimerization activity; ISS:UniProtKB.::GO:0004722; F:protein serine/threonine phosphatase activity; IDA:RGD.
GO:0007126; P:meiosis; IEA:UniProtKB-KW.::GO:0006470; P:protein dephosphorylation; IDA:RGD.::GO:0070208; P:protein heterotrimerization; IMP:MGI.::GO:0031952; P:regulation of protein autophosphorylation; IMP:MGI.::GO:0042176; P:regulation of protein catabolic process; IMP:MGI.::GO:0010469; P:regulation of receptor activity; IMP:MGI.
142P63330    309   PP2AA_MOUSE Serine/threonine-protein phosphat...2664e-54     190     37     55GO:0000775; C:chromosome, centromeric region; IDA:UniProtKB.::GO:0005829; C:cytosol; IDA:MGI.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IDA:MGI.::GO:0000159; C:protein phosphatase type 2A complex; IDA:MGI.::GO:0000922; C:spindle pole; IEA:UniProtKB-SubCell.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0008022; F:protein C-terminus binding; IPI:MGI.::GO:0046982; F:protein heterodimerization activity; ISS:UniProtKB.::GO:0004722; F:protein serine/threonine phosphatase activity; TAS:MGI.
GO:0007126; P:meiosis; IEA:UniProtKB-KW.::GO:0007498; P:mesoderm development; IMP:MGI.::GO:0006470; P:protein dephosphorylation; TAS:MGI.::GO:0051726; P:regulation of cell cycle; TAS:MGI.
143O82734    324   PP18_ARATH Serine/threonine-protein phosphata...2934e-54     191     36     54
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004722; F:protein serine/threonine phosphatase activity; IDA:TAIR.
144Q05547    302   PP13_DROME Serine/threonine-protein phosphata...2485e-54     190     39     58
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004722; F:protein serine/threonine phosphatase activity; IDA:FlyBase.
GO:0006470; P:protein dephosphorylation; IDA:FlyBase.
145P48452    521   PP2BA_BOVIN Serine/threonine-protein phosphat...2825e-54     195     38     56GO:0005829; C:cytosol; TAS:Reactome.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0033192; F:calmodulin-dependent protein phosphatase activity; TAS:UniProtKB.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
146Q08209    521   PP2BA_HUMAN Serine/threonine-protein phosphat...2825e-54     195     38     56GO:0005955; C:calcineurin complex; NAS:UniProtKB.::GO:0005737; C:cytoplasm; IDA:HPA.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0005634; C:nucleus; IDA:HPA.
GO:0005509; F:calcium ion binding; NAS:UniProtKB.::GO:0005516; F:calmodulin binding; IDA:UniProtKB.::GO:0033192; F:calmodulin-dependent protein phosphatase activity; TAS:UniProtKB.::GO:0008144; F:drug binding; IDA:UniProtKB.::GO:0019899; F:enzyme binding; IDA:UniProtKB.::GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
GO:0035690; P:cellular response to drug; IDA:UniProtKB.::GO:0006470; P:protein dephosphorylation; NAS:UniProtKB.::GO:0042110; P:T cell activation; TAS:UniProtKB.
147P63329    521   PP2BA_RAT Serine/threonine-protein phosphatas...2836e-54     195     38     57GO:0005955; C:calcineurin complex; IDA:RGD.::GO:0005829; C:cytosol; IDA:RGD.::GO:0016020; C:membrane; IDA:RGD.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005625; C:soluble fraction; IDA:RGD.
GO:0004723; F:calcium-dependent protein serine/threonine phosphatase activity; IDA:RGD.::GO:0005516; F:calmodulin binding; IDA:RGD.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0046982; F:protein heterodimerization activity; IDA:RGD.
GO:0071333; P:cellular response to glucose stimulus; IMP:BHF-UCL.::GO:0045955; P:negative regulation of calcium ion-dependent exocytosis; IC:BHF-UCL.::GO:0046676; P:negative regulation of insulin secretion; IMP:BHF-UCL.::GO:0006470; P:protein dephosphorylation; IDA:RGD.::GO:0001975; P:response to amphetamine; IEP:RGD.
148P63328    521   PP2BA_MOUSE Serine/threonine-protein phosphat...2836e-54     195     38     57GO:0005955; C:calcineurin complex; IDA:MGI.::GO:0005829; C:cytosol; IDA:MGI.::GO:0005792; C:microsome; IDA:MGI.::GO:0005739; C:mitochondrion; IDA:MGI.::GO:0005634; C:nucleus; IDA:MGI.::GO:0030018; C:Z disc; IDA:MGI.
GO:0004723; F:calcium-dependent protein serine/threonine phosphatase activity; TAS:Reactome.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0033173; P:calcineurin-NFAT signaling cascade; IDA:MGI.::GO:0006816; P:calcium ion transport; IMP:MGI.::GO:0000082; P:G1/S transition of mitotic cell cycle; IMP:MGI.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IGI:MGI.::GO:0006606; P:protein import into nucleus; IDA:MGI.::GO:0060079; P:regulation of excitatory postsynaptic membrane potential; IGI:MGI.::GO:0050804; P:regulation of synaptic transmission; IMP:MGI.::GO:0006950; P:response to stress; IDA:MGI.::GO:0048741; P:skeletal muscle fiber development; IMP:MGI.::GO:0014883; P:transition between fast and slow fiber; IDA:MGI.
149Q05681    558   PP2B_NEUCR Serine/threonine-protein phosphata...3126e-54     196     38     53
GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004721; F:phosphoprotein phosphatase activity; IEA:UniProtKB-KW.
150P23635    309   PP2A1_SCHPO Minor serine/threonine-protein ph...2297e-54     189     42     57GO:0005634; C:nucleus; IDA:PomBase.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004721; F:phosphoprotein phosphatase activity; TAS:PomBase.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0006470; P:protein dephosphorylation; IMP:PomBase.::GO:2000765; P:regulation of cytoplasmic translation; ISS:PomBase.::GO:0007346; P:regulation of mitotic cell cycle; IMP:PomBase.::GO:0007165; P:signal transduction; NAS:PomBase.
151Q9Y0B7    305   PP4C_DICDI Serine/threonine-protein phosphata...2422e-53     188     40     58GO:0005737; C:cytoplasm; IDA:dictyBase.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0030289; C:protein phosphatase 4 complex; IDA:dictyBase.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004722; F:protein serine/threonine phosphatase activity; IDA:dictyBase.
GO:0050920; P:regulation of chemotaxis; IGI:dictyBase.::GO:0031156; P:regulation of sorocarp development; IMP:dictyBase.
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