Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YGR108W
Length:
471
Number of sequences:
5887
Description:
YGR108W CLB1 SGDID:S000003340, Chr VII from 703636-705051, Genome Release 64-1-1, Verified ORF, "B-type cyclin involved in cell cycle progression; activates Cdc28p to promote the transition from G2 to M phase; accumulates during G2 and M, then targeted via a destruction box motif for ubiquitin-mediated degradation by the proteasome"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
121O42575    408   CCNE3_XENLA G1/S-specific cyclin-E3 OS=Xenopu...1371e-16     85.1     36     61GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0019901; F:protein kinase binding; IEA:InterPro.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0000079; P:regulation of cyclin-dependent protein kinase activity; IEA:InterPro.
122P50756    408   CCNE1_XENLA G1/S-specific cyclin-E1 OS=Xenopu...1372e-16     84.7     36     61GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0019901; F:protein kinase binding; IEA:InterPro.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0000079; P:regulation of cyclin-dependent protein kinase activity; IEA:InterPro.
123Q91780    408   CCNE2_XENLA G1/S-specific cyclin-E2 OS=Xenopu...1372e-16     84.7     36     61GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0019901; F:protein kinase binding; IEA:InterPro.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0000079; P:regulation of cyclin-dependent protein kinase activity; IEA:InterPro.
124Q59YH3    693   CG11_CANAL G1/S-specific cyclin CCN1 OS=Candi...2152e-16     85.5     31     47GO:0005634; C:nucleus; IEA:InterPro.
GO:0016538; F:cyclin-dependent protein kinase regulator activity; ISS:CGD.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0035690; P:cellular response to drug; IMP:CGD.::GO:0000082; P:G1/S transition of mitotic cell cycle; IMP:CGD.::GO:0030448; P:hyphal growth; IMP:CGD.::GO:0030011; P:maintenance of cell polarity; IMP:CGD.::GO:0000079; P:regulation of cyclin-dependent protein kinase activity; IMP:CGD.
125P0CY18    698   CG11_CANAX G1/S-specific cyclin CLN1 OS=Candi...2152e-16     85.5     31     47GO:0005634; C:nucleus; IEA:InterPro.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.
126C4YR54    698   CG11_CANAW G1/S-specific cyclin CCN1 OS=Candi...2152e-16     85.5     31     47GO:0005634; C:nucleus; IEA:InterPro.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.
127O15995    424   CCNE_HEMPU G1/S-specific cyclin-E OS=pulcherr...1372e-16     84.7     33     60GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0019901; F:protein kinase binding; IEA:InterPro.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0000079; P:regulation of cyclin-dependent protein kinase activity; IEA:InterPro.
128P24864    410   CCNE1_HUMAN G1/S-specific cyclin-E1 OS=Homo s...984e-16     84     44     65GO:0005829; C:cytosol; TAS:Reactome.::GO:0005654; C:nucleoplasm; TAS:Reactome.
GO:0050681; F:androgen receptor binding; NAS:UniProtKB.::GO:0003713; F:transcription coactivator activity; NAS:UniProtKB.
GO:0030521; P:androgen receptor signaling pathway; NAS:UniProtKB.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0045893; P:positive regulation of transcription, DNA-dependent; NAS:UniProtKB.::GO:0000079; P:regulation of cyclin-dependent protein kinase activity; IEA:InterPro.::GO:0000083; P:regulation of transcription involved in G1/S phase of mitotic cell cycle; TAS:Reactome.
129P49707    407   CCNE1_CHICK G1/S-specific cyclin-E1 OS=Gallus...1065e-16     83.6     41     63GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0019901; F:protein kinase binding; IEA:InterPro.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0000079; P:regulation of cyclin-dependent protein kinase activity; IEA:InterPro.
130Q9LM91    265   CCB25_ARATH Cyclin-B2-5 OS=Arabidopsis thalia...1778e-16     80.9     28     50GO:0005634; C:nucleus; IEA:InterPro.
GO:0019901; F:protein kinase binding; IEA:InterPro.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0000079; P:regulation of cyclin-dependent protein kinase activity; IEA:InterPro.
131P39949    411   CCNE1_RAT G1/S-specific cyclin-E1 OS=Rattus n...980.000000000000002     81.6     41     65GO:0005813; C:centrosome; IDA:RGD.::GO:0005634; C:nucleus; IDA:RGD.
GO:0019901; F:protein kinase binding; IPI:RGD.
GO:0001547; P:antral ovarian follicle growth; IEP:RGD.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0031670; P:cellular response to nutrient; IEP:RGD.::GO:0001889; P:liver development; IEP:RGD.::GO:0031100; P:organ regeneration; IEP:RGD.::GO:0045597; P:positive regulation of cell differentiation; IDA:RGD.::GO:0000079; P:regulation of cyclin-dependent protein kinase activity; IEA:InterPro.::GO:0051412; P:response to corticosterone stimulus; IEP:RGD.::GO:0034097; P:response to cytokine stimulus; IEP:RGD.::GO:0042493; P:response to drug; IEP:RGD.::GO:0032355; P:response to estradiol stimulus; IEP:RGD.::GO:0045471; P:response to ethanol; IEP:RGD.::GO:0051597; P:response to methylmercury; IEP:RGD.::GO:0010243; P:response to organic nitrogen; IEP:RGD.::GO:0032570; P:response to progesterone stimulus; IEP:RGD.::GO:0014074; P:response to purine-containing compound; IEP:RGD.::GO:0033197; P:response to vitamin E; IEP:RGD.
132Q61457    408   CCNE1_MOUSE G1/S-specific cyclin-E1 OS=Mus mu...990.000000000000003     80.9     40     66GO:0000307; C:cyclin-dependent protein kinase holoenzyme complex; IPI:MGI.::GO:0005634; C:nucleus; IDA:MGI.
GO:0016538; F:cyclin-dependent protein kinase regulator activity; IDA:MGI.::GO:0016301; F:kinase activity; IDA:MGI.::GO:0019901; F:protein kinase binding; IPI:MGI.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0006270; P:DNA-dependent DNA replication initiation; IMP:MGI.::GO:0006468; P:protein phosphorylation; IDA:MGI.::GO:0000079; P:regulation of cyclin-dependent protein kinase activity; IEA:InterPro.::GO:0016055; P:Wnt receptor signaling pathway; IDA:MGI.
133Q8MUK3    518   CCNE_CAEBR G1/S-specific cyclin-E OS=Caenorha...1190.0000000000001     76.3     39     56GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0016538; F:cyclin-dependent protein kinase regulator activity; ISS:UniProtKB.::GO:0019901; F:protein kinase binding; IEA:InterPro.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0000082; P:G1/S transition of mitotic cell cycle; ISS:UniProtKB.::GO:0000079; P:regulation of cyclin-dependent protein kinase activity; IEA:InterPro.::GO:0007088; P:regulation of mitosis; ISS:UniProtKB.
134P55169    292   CCND1_CHICK G1/S-specific cyclin-D1 OS=Gallus...1620.0000000000003     73.6     27     52GO:0000307; C:cyclin-dependent protein kinase holoenzyme complex; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0019901; F:protein kinase binding; IEA:InterPro.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0000082; P:G1/S transition of mitotic cell cycle; ISS:UniProtKB.::GO:0031571; P:mitotic cell cycle G1/S transition DNA damage checkpoint; ISS:UniProtKB.::GO:0045737; P:positive regulation of cyclin-dependent protein kinase activity; ISS:UniProtKB.::GO:0001934; P:positive regulation of protein phosphorylation; ISS:UniProtKB.::GO:0070141; P:response to UV-A; ISS:UniProtKB.
135P25322    295   CCND1_MOUSE G1/S-specific cyclin-D1 OS=Mus mu...1790.000000000002     71.6     26     51GO:0000307; C:cyclin-dependent protein kinase holoenzyme complex; IPI:UniProtKB.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.::GO:0005654; C:nucleoplasm; TAS:Reactome.
GO:0016538; F:cyclin-dependent protein kinase regulator activity; IDA:MGI.::GO:0004672; F:protein kinase activity; IDA:MGI.::GO:0019901; F:protein kinase binding; IPI:UniProtKB.
GO:0060070; P:canonical Wnt receptor signaling pathway; IMP:MGI.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0030968; P:endoplasmic reticulum unfolded protein response; IDA:MGI.::GO:0045444; P:fat cell differentiation; IDA:MGI.::GO:0000082; P:G1/S transition of mitotic cell cycle; ISS:UniProtKB.::GO:0007595; P:lactation; IMP:MGI.::GO:0060749; P:mammary gland alveolus development; IMP:MGI.::GO:0033598; P:mammary gland epithelial cell proliferation; IGI:MGI.::GO:0031571; P:mitotic cell cycle G1/S transition DNA damage checkpoint; ISS:UniProtKB.::GO:0030857; P:negative regulation of epithelial cell differentiation; IGI:MGI.::GO:0030178; P:negative regulation of Wnt receptor signaling pathway; IMP:MGI.::GO:0045737; P:positive regulation of cyclin-dependent protein kinase activity; ISS:UniProtKB.::GO:0033601; P:positive regulation of mammary gland epithelial cell proliferation; IGI:MGI.::GO:0001934; P:positive regulation of protein phosphorylation; ISS:UniProtKB.::GO:0000320; P:re-entry into mitotic cell cycle; IDA:MGI.::GO:0070141; P:response to UV-A; ISS:UniProtKB.
136Q10PQ9    469   CCSDS_ORYSJ Cyclin-SDS-like OS=Oryza sativa s...1510.000000000002     72.8     32     54GO:0005634; C:nucleus; IEA:InterPro.
GO:0019901; F:protein kinase binding; IEA:InterPro.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0000079; P:regulation of cyclin-dependent protein kinase activity; IEA:InterPro.
137Q14094    377   CCNI_HUMAN Cyclin-I OS=Homo sapiens (Human). ...1080.000000000002     72.4     35     56
GO:0007283; P:spermatogenesis; NAS:UniProtKB.
138O01501    524   CCNE_CAEEL G1/S-specific cyclin-E OS=Caenorha...1090.000000000002     72.8     35     61GO:0000307; C:cyclin-dependent protein kinase holoenzyme complex; ISS:WormBase.::GO:0005634; C:nucleus; IDA:UniProtKB.
GO:0016538; F:cyclin-dependent protein kinase regulator activity; IDA:UniProtKB.::GO:0019901; F:protein kinase binding; IEA:InterPro.
GO:0010171; P:body morphogenesis; IMP:WormBase.::GO:0000910; P:cytokinesis; IMP:WormBase.::GO:0042023; P:DNA endoreduplication; IMP:WormBase.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0000082; P:G1/S transition of mitotic cell cycle; IDA:UniProtKB.::GO:0007281; P:germ cell development; IMP:WormBase.::GO:0051729; P:germline cell cycle switching, mitotic to meiotic cell cycle; IMP:WormBase.::GO:0040007; P:growth; IMP:WormBase.::GO:0040035; P:hermaphrodite genitalia development; IMP:WormBase.::GO:0071850; P:mitotic cell cycle arrest; IGI:WormBase.::GO:0002119; P:nematode larval development; IMP:WormBase.::GO:0008284; P:positive regulation of cell proliferation; IMP:WormBase.::GO:0045737; P:positive regulation of cyclin-dependent protein kinase activity; ISS:WormBase.::GO:0040026; P:positive regulation of vulval development; IMP:WormBase.::GO:0010608; P:posttranscriptional regulation of gene expression; IMP:WormBase.::GO:0006468; P:protein phosphorylation; IMP:WormBase.::GO:0007088; P:regulation of mitosis; IDA:UniProtKB.
139P42753    376   CCD31_ARATH Cyclin-D3-1 OS=Arabidopsis thalia...1630.000000000003     71.6     29     52GO:0005634; C:nucleus; IDA:TAIR.
GO:0005515; F:protein binding; IPI:IntAct.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0000082; P:G1/S transition of mitotic cell cycle; IMP:TAIR.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0042127; P:regulation of cell proliferation; IGI:TAIR.::GO:0009741; P:response to brassinosteroid stimulus; IGI:TAIR.::GO:0009735; P:response to cytokinin stimulus; IMP:TAIR.::GO:0009744; P:response to sucrose stimulus; IEP:TAIR.
140P39948    295   CCND1_RAT G1/S-specific cyclin-D1 OS=Rattus n...1790.000000000004     70.1     26     51GO:0000307; C:cyclin-dependent protein kinase holoenzyme complex; ISS:UniProtKB.::GO:0005737; C:cytoplasm; IDA:RGD.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IDA:RGD.
GO:0019901; F:protein kinase binding; IPI:RGD.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0000082; P:G1/S transition of mitotic cell cycle; ISS:UniProtKB.::GO:0033327; P:Leydig cell differentiation; IMP:RGD.::GO:0001889; P:liver development; IEP:RGD.::GO:0031571; P:mitotic cell cycle G1/S transition DNA damage checkpoint; ISS:UniProtKB.::GO:0031100; P:organ regeneration; IEP:RGD.::GO:0045737; P:positive regulation of cyclin-dependent protein kinase activity; ISS:UniProtKB.::GO:0001934; P:positive regulation of protein phosphorylation; ISS:UniProtKB.::GO:0051592; P:response to calcium ion; IEP:RGD.::GO:0051412; P:response to corticosterone stimulus; IEP:RGD.::GO:0042493; P:response to drug; IEP:RGD.::GO:0043627; P:response to estrogen stimulus; IEP:RGD.::GO:0045471; P:response to ethanol; IEP:RGD.::GO:0010039; P:response to iron ion; IEP:RGD.::GO:0032026; P:response to magnesium ion; IEP:RGD.::GO:0014070; P:response to organic cyclic compound; IEP:RGD.::GO:0010243; P:response to organic nitrogen; IDA:RGD.::GO:0070141; P:response to UV-A; ISS:UniProtKB.::GO:0033197; P:response to vitamin E; IEP:RGD.::GO:0010165; P:response to X-ray; IEP:RGD.
141Q2KI22    295   CCND1_BOVIN G1/S-specific cyclin-D1 OS=Bos ta...1710.000000000005     69.7     27     53GO:0000307; C:cyclin-dependent protein kinase holoenzyme complex; ISS:UniProtKB.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0000082; P:G1/S transition of mitotic cell cycle; ISS:UniProtKB.::GO:0031571; P:mitotic cell cycle G1/S transition DNA damage checkpoint; ISS:UniProtKB.::GO:0045737; P:positive regulation of cyclin-dependent protein kinase activity; ISS:UniProtKB.::GO:0001934; P:positive regulation of protein phosphorylation; ISS:UniProtKB.::GO:0070141; P:response to UV-A; ISS:UniProtKB.
142Q90459    291   CCND1_DANRE G1/S-specific cyclin-D1 OS=Danio ...1830.000000000009     69.3     25     48GO:0005634; C:nucleus; IEA:InterPro.
GO:0019901; F:protein kinase binding; IEA:InterPro.
GO:0048593; P:camera-type eye morphogenesis; IMP:ZFIN.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0000082; P:G1/S transition of mitotic cell cycle; ISS:UniProtKB.::GO:0031571; P:mitotic cell cycle G1/S transition DNA damage checkpoint; ISS:UniProtKB.::GO:0000079; P:regulation of cyclin-dependent protein kinase activity; IEA:InterPro.
143Q9Z2V9    377   CCNI_MOUSE Cyclin-I OS=Mus musculus (Mouse). ...1070.000000000009     70.1     35     55
GO:0051726; P:regulation of cell cycle; TAS:MGI.
144Q8WNW2    288   CCND2_PIG G1/S-specific cyclin-D2 OS=Sus scro...1520.00000000002     68.2     27     50
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.
145Q0P5D3    289   CCND2_BOVIN G1/S-specific cyclin-D2 OS=Bos ta...1520.00000000002     68.2     27     49
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.
146Q64HP0    295   CCND1_CANFA G1/S-specific cyclin-D1 OS=Canis ...1460.00000000003     67.8     27     53GO:0000307; C:cyclin-dependent protein kinase holoenzyme complex; ISS:UniProtKB.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0000082; P:G1/S transition of mitotic cell cycle; ISS:UniProtKB.::GO:0031571; P:mitotic cell cycle G1/S transition DNA damage checkpoint; ISS:UniProtKB.::GO:0045737; P:positive regulation of cyclin-dependent protein kinase activity; ISS:UniProtKB.::GO:0001934; P:positive regulation of protein phosphorylation; ISS:UniProtKB.::GO:0070141; P:response to UV-A; ISS:UniProtKB.
147Q5SCB5    374   CCND_OSTTA Cyclin-D OS=Ostreococcus tauri. GN...2500.00000000005     67.8     26     41GO:0005634; C:nucleus; IEA:InterPro.
GO:0019901; F:protein kinase binding; IEA:InterPro.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0000079; P:regulation of cyclin-dependent protein kinase activity; IEA:InterPro.
148Q04827    288   CCND2_RAT G1/S-specific cyclin-D2 OS=Rattus n...1520.00000000006     66.6     26     49
GO:0019901; F:protein kinase binding; IPI:RGD.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0032869; P:cellular response to insulin stimulus; IEP:RGD.::GO:0000082; P:G1/S transition of mitotic cell cycle; IMP:RGD.::GO:0001889; P:liver development; IEP:RGD.::GO:0001541; P:ovarian follicle development; IEP:RGD.::GO:0050679; P:positive regulation of epithelial cell proliferation; IMP:RGD.::GO:0045664; P:regulation of neuron differentiation; IEP:RGD.::GO:0051591; P:response to cAMP; IEP:RGD.::GO:0032355; P:response to estradiol stimulus; IEP:RGD.::GO:0045471; P:response to ethanol; IEP:RGD.::GO:0014070; P:response to organic cyclic compound; IEP:RGD.::GO:0033574; P:response to testosterone stimulus; IEP:RGD.::GO:0007283; P:spermatogenesis; IEP:RGD.
149P30280    289   CCND2_MOUSE G1/S-specific cyclin-D2 OS=Mus mu...1520.00000000006     66.6     26     49
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.
150P25009    359   PUC1_SCHPO Cyclin puc1 OS=Schizosaccharomyces...1390.00000000007     67.4     34     51GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.
GO:0016538; F:cyclin-dependent protein kinase regulator activity; NAS:PomBase.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0000079; P:regulation of cyclin-dependent protein kinase activity; NAS:PomBase.::GO:0007096; P:regulation of exit from mitosis; IMP:PomBase.
151P50755    291   CCND1_XENLA G1/S-specific cyclin-D1 OS=Xenopu...1660.00000000009     66.2     26     49GO:0005634; C:nucleus; IEA:InterPro.
GO:0019901; F:protein kinase binding; IEA:InterPro.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0000082; P:G1/S transition of mitotic cell cycle; ISS:UniProtKB.::GO:0031571; P:mitotic cell cycle G1/S transition DNA damage checkpoint; ISS:UniProtKB.::GO:0000079; P:regulation of cyclin-dependent protein kinase activity; IEA:InterPro.
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